Calcium phosphate scaffolds combined with bone morphogenetic proteins or mesenchymal stem cells in bone tissue engineering.

abstract：OBJECTIVE:Parkinson's disease (PD) is featured with motor disorder and nonmotor manifestations including psychological symptoms, autonomic nervous system dysfunction, and paresthesia, which results in great inconvenience to the patients' life. The apolipoprotein (Apo) superfamily, as a group of potentially modifiable b...

journal_title：Chinese medical journal

authors： Li L,Liu MS,Li GQ,Tang J,Liao Y,Zheng Y,Guo TL,Kang X,Yuan MT

更新日期：2017-11-05 00:00:00

abstract：BACKGROUND:Pelizaeus-Merzbacher disease (PMD) is a rare X-linked recessive disorder with symptoms including nystagmus, impaired motor development, ataxia, and progressive spasticity. The proteolipid protein 1 (PLP1) gene is the only pathogenic gene of PMD. Duplication of the PLP1 gene is the most frequent gene defect, ...

journal_title：Chinese medical journal

authors： Wang JM,Wu Y,Wang HF,Deng YH,Yang YL,Qin J,Li XY,Wu XR,Jiang YW

更新日期：2008-09-05 00:00:00

abstract：:The model was established in male rabbits with experimental atherosclerosis, which was induced by diet cholesterol (0.5 g per day for 8 weeks), by means of intravenous injection of one unit of pituitrin (P.P.). To evaluate the effects of aspirin, heparin and viper venom (VV) on this model, 26 male rabbits were divided...

journal_title：Chinese medical journal

authors： Zhang W,Wang P,Chen Z,Fan Y

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:The duration of viral shedding and the transmission of 2009 H1N1 influenza among individuals, especially among the younger population with mild illness, are not well understood now. The aim of this study was to determine the viral shedding of the young adult patients with mild 2009 H1N1 influenza in China. ...

journal_title：Chinese medical journal

authors： Jia N,Gao Y,Suo JJ,Xie LJ,Yan ZQ,Xing YB,He L,Liu YX

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:A satisfactory animal model of breast cancer metastasizing to bone is unavailable. In this study, we used human breast cancer stem-like cells and human bone to build a novel "human-source" model of human breast cancer skeletal metastasis. METHODS:Human breast cancer stem-like cells, the CD44+/CD24-/lower su...

journal_title：Chinese medical journal

authors： Ling LJ,Wang S,Liu XA,Shen EC,Ding Q,Lu C,Xu J,Cao QH,Zhu HQ,Wang F

更新日期：2008-10-20 00:00:00

abstract：OBJECTIVE:To evaluate the effects of nitric oxide inhibitor on prostacyclin (PGI2) biosynthesis and the role of PGI2 in hyperhemodynamics of portal hypertension. METHODS:Sprague Dawley rats were divided into four groups: intrahepatic portal hypertension (IHPH) by injection of CCl4, prehepatic portal hypertension (PHPH...

journal_title：Chinese medical journal

authors： Cao H,Wu Z,Zhou J,Chen Z,Kuang Y

更新日期：1999-06-01 00:00:00

abstract：:The radiographic measurement of the prevertebral soft tissue of cervical vertebrae was performed in 87 normal adults. According to the results of the measurement, 10 mm and 20 mm were used as the upper limit normal values of the retropharyngeal and retrotracheal space respectively. We conclude that although the widene...

journal_title：Chinese medical journal

authors： Dai LY,Jia LS

更新日期：1994-06-01 00:00:00

abstract：OBJECTIVE:To investigate the relationship between vascular endothelial growth factor C (VEGF-C) expression, VEGFR-3 expression, lymphangiogenesis and angiogenesis in human non-small cell lung cancer (NSCLC). METHODS:Seventy-six NSCLC samples were stained for VEGF-C, VEGFR-3 and CD34 with immunohistochemical methods. A...

journal_title：Chinese medical journal

authors： Li Q,Dong X,Gu W,Qiu X,Wang E

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:We assessed whether the CaNa2 EDTA could improve the accumulation of protoporphyrin IX (PpIX) and photosensitisation in HEp-2 cells as well as the depth of treatment of skin cancers on the topical 5-Aminolaevulinic acid (5-ALA) PDT. METHODS:HEp-2 cells were incubated with 5-ALA (0-1 mmol/L) and CaNa2EDTA (0...

journal_title：Chinese medical journal

authors： Liu HF,Xu SZ,Zhang CR

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:Methylmalonic acidemia (MMA) is a multifactorial autosomal recessive inborn error of organic acid metabolism, often presenting with neurological symptoms. As neurological disorders are often related to white matter injury, diffusion tensor imaging (DTI) is an excellent tool for assessment of white matter inj...

journal_title：Chinese medical journal

authors： Gao Y,Guan WY,Wang J,Zhang YZ,Li YH,Han LS

更新日期：2009-04-20 00:00:00

abstract：BACKGROUND:Combination therapy is an effective method to reduce the blood pressure (BP) for patients with hypertension. This study was performed to evaluate the efficacy and safety of benazepril/lercanidipine compared with benazepril alone in patients with mild-to-moderate hypertension. METHODS:One hundred and eighty-...

journal_title：Chinese medical journal

authors： Chen T,Chen GH,Yang TS,Zhong ZY,An WS,Zhang XX,Li JD

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:To analyse the relationship between age and treatment with captopril after acute myocardial infarction (AMI). METHODS:In a randomized trial, 822 patients with a first AMI received conventional medical treatment, including intravenous thrombolytic therapy and oral aspirin or metoprolol, and then were randomly...

journal_title：Chinese medical journal

authors： Cai X,Shen W,Gong L

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:The baseline characteristics of patients in a multinational trial are possibly related to cardiovascular outcome. This study compared the baseline characteristics of patients recruited in China with those recruited in other countries. METHODS:A total of 508 Chinese hypertensive men and 728 women over the ag...

journal_title：Chinese medical journal

authors： Liu LS,Wang JG,Shu-Ping M,Wang W,Lu FH,Zhang LQ,Banya W,Peters R,Beckett N,Fletcher A,Bulpitt CJ

更新日期：2008-08-20 00:00:00

abstract：:Osteoarthritis (OA) models in bipedal rats were used to study the immune response, including the changes of IgG, antibody dependent cytotoxicity tests toward articular chondrocytes and the matrix. The results revealed significant difference between the bipedal and the quadruped rats. Immunological studies have proved ...

journal_title：Chinese medical journal

authors： Chen YP,Yang Y,Chen BX

更新日期：1991-03-01 00:00:00

abstract：BACKGROUND:Mesenteric artery thrombosis is prone to occur at specific arterial regions with different fluid flow patterns, yet mechanistic links between blood flow and vascular function remain unclear. This study aimd to investigate the role of blood flow in regulation of vascular function and gene expression in rats. ...

journal_title：Chinese medical journal

authors： Xia S,Deng CS

更新日期：2009-05-20 00:00:00

abstract：Background:The role of postradiation systemic therapy in non-small cell lung cancer (NSCLC) patients with brain metastasis (BM) was controversial. Thus, we explored the role of Radiation Therapy Oncology Group recursive partitioning analysis (RTOG-RPA) and graded prognostic assessment (GPA) in identifying population wh...

journal_title：Chinese medical journal

authors： Liu S,Chen P,Liu YW,Gu XN,Qiu XG,Li B

更新日期：2018-05-20 00:00:00

abstract：:Thallium-201 dipyridamole test (Tl-201DT) has high sensitivity and specificity in the assessment of coronary disease (CAD), but is not always available. We proposed impedance cardiography DT (IDT)instead. To determine the characteristic changes of impedance cardiogram (ICG) in patients with typical angina and to compa...

journal_title：Chinese medical journal

authors： Chen G,Mao HY,Wei KQ,Zhang DC,Guo QG

更新日期：1989-02-01 00:00:00

abstract：BACKGROUND:Alpha 2A adrenergic receptor (AR) is a subtype of α2 AR belonging to G protein-coupled receptors, and exerts a variety of biological effects. Recent studies have demonstrated that the α2A AR activation was closely related with inflammatory reaction. The present study aimed to investigate the influence of α2A...

journal_title：Chinese medical journal

authors： Lin Y,Zhu X,Yao WZ,Yang YL,A LT,Chen L

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:To characterize the mRNA expression of CXC chemokine IL-8, CC chemokine monocyte chemothractant protein-1 (MCP-1) and regulated on activation, normal T cell expressed and secreted (RANTES), and a newly defined DC chemokine DC-CK1 as well as the expression of IL-8 receptor, MCP-1 receptor and RANTES receptor i...

journal_title：Chinese medical journal

authors： Zhu K,Shen Q,Ulrich M,Zheng M

更新日期：2000-12-01 00:00:00

abstract：OBJECTIVE:To examine the effect of selective head cooling (SHC) on brain cell membrane activity involving ATPase, phospholipase A2, content of total membrane phospholipids during postischemic reperfusion, so as to elucidate the possible underlying mechanism on resuscitating effect of SHC. MATERIALS AND METHODS:Complet...

journal_title：Chinese medical journal

authors： Duan M,Li D,Xu J

更新日期：1996-06-01 00:00:00

abstract：:A family with Fabry's disease including 2 hemizygotes and 3 heterozygotes is reported. The ocular manifestations include tortuosity of conjunctival vessels, Fabry's deposits underlying the anterior capsule of the lens and the whorl-like corneal dystrophy. Foam cells or mulberry cells in the urinary sediment and varyin...

journal_title：Chinese medical journal

authors： Bao LL,Guo LL,Li SN,Xiao J,Yang JS,Bai LR,Ye PM,Guo ZT,Liu DW

更新日期：1990-02-01 00:00:00

abstract：BACKGROUND:Intravertebral and general anesthesia (GA) are two main anesthesia approaches but both have defects. This study was aimed to evaluate the effect of subarachnoid anesthesia combined with propofol target-controlled infusion (TCI) on blood loss and transfusion for total hip arthroplasty (THA) in elderly patient...

journal_title：Chinese medical journal

authors： Xu CS,Qu XD,Qu ZJ,Wang G,Wang HJ

更新日期：2020-03-20 00:00:00

abstract：:Lymphocytes from regional lymph nodes of patients with ovarian carcinoma were immortalized by fusing them with a nonsecreting cell line of murine myeloma (Sp2/0-Ag14). The fusion rate was 0-87.5%. By early cloning and recloning, a hybrid cell line, named HMD4, was established. It has stably secreted human IgG for more...

journal_title：Chinese medical journal

authors： Cui H,Qian HN,Feng J,Fu TY,Wei P,Fu ZY

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND:Acinetobacter baumanii (A. baumanii ) remains an important microbial pathogen resulting in nosocomial acquired infections with significant morbidity and mortality. The mechanism by which nosocomial bacteria, like A. baumanii, attain multidrug resistance to antibiotics is of considerable interest. The aim in ...

journal_title：Chinese medical journal

authors： Dai N,Li DZ,Chen JC,Chen YS,Geng R,Hu YH,Yang JP,DU J,Hu CP,Zhang W,Li JS,Yu Q,Wan HY,Mu L,Zhong XN,Wei LP,Ma JJ,Wang QY,Hu K,Tian GZ,Cai SX,Wang RQ,He B,Wang SQ,Wang ZW,Zhao SR,Gao ZC

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Asthma is a heterogeneous disease for which a strong genetic basis has been firmly established. Until now no studies have been undertaken to systemically explore the network of asthma-related genes using an internally developed literature-based discovery approach. This study was to explore asthma-related gen...

journal_title：Chinese medical journal

authors： Liang R,Wang L,Wang G

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Endothelial dysfunction is thought to be critical events in the pathogenesis of Alzheimer's disease (AD). Endothelial progenitor cells (EPCs) have provided insight into maintaining and repairing endothelial function. To study the relation between EPCs and AD, we explored the number of circulating EPCs in pat...

journal_title：Chinese medical journal

authors： Kong XD,Zhang Y,Liu L,Sun N,Zhang MY,Zhang JN

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Chronic graft-versus-host disease (GVHD), the commonest long-term complication after allogeneic hematopoietic stem cell transplantation (HSCT), has a negative impact on patients' health related quality of life (HRQoL). This study was designed to investigate the HRQoL in patients with chronic GVHD in China. ...

journal_title：Chinese medical journal

authors： Mo XD,Xu LP,Liu DH,Chen YH,Zhang XH,Chen H,Han W,Wang Y,Wang FR,Wang JZ,Liu KY,Huang XJ

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Low molecular weight heparin (LMWH), as one of anticoagulant drugs, has been used for the treatment of chronic obstructive pulmonary disease (COPD) with prethrombotic state, but the specific use time is unclear. The aim of the study is to observe the effect of LMWH at two different periods of prethrombotic s...

journal_title：Chinese medical journal

authors： Wang Y,Sun N,Cheng Z,Tong L

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Survivin is an oncoprotein silenced in normal mature tissues but reactivated in serous ovarian cancer (SOC). Although transcriptional activation is assumed for its overexpression, the long 3'-untranslated region (3'-UTR) in survivin gene, which contains many alternate polyadenylation (APA) sites, implies a p...

journal_title：Chinese medical journal

authors： He XJ,Zhang Q,Ma LP,Li N,Chang XH,Zhang YJ

更新日期：2016-05-20 00:00:00

abstract：:102 patients with nasal polyps receiving ND: YAG laser surgery or routine surgery were followed up for 18-36 months. The postoperative recurrence rates were 40.6% (24/54) and 66.6% (32/48) respectively for the patients of the two groups. Laser surgery is marked by less bleeding, no postoperative packing of the nose an...

journal_title：Chinese medical journal

authors： Zhang BQ

更新日期：1993-09-01 00:00:00