New insight into genes in association with asthma: literature-based mining and network centrality analysis.

abstract：BACKGROUND:Anisodamine is widely used in therapy for treating acute glomerulonephritis and diabetic nephropathy because it can improve renal microcirculation. We performed a study to evaluate the preventive effects of anisodamine against contrast-induced nephropathy (CIN) in type 2 diabetics with renal insufficiency un...

journal_title：Chinese medical journal

authors： Geng W,Fu XH,Gu XS,Wang YB,Wang XC,Li W,Jiang YF,Hao GZ,Fan WZ,Xue L

更新日期：2012-10-01 00:00:00

abstract：Objective:Endothelial cells (ECs) are important metabolic and endocrinal organs which play a significant role in regulating vascular function. Vascular ECs, located between the blood and vascular tissues, can not only complete the metabolism of blood and interstitial fluid but also synthesize and secrete a variety of b...

journal_title：Chinese medical journal

authors： Meng LB,Chen K,Zhang YM,Gong T

更新日期：2018-10-05 00:00:00

abstract：BACKGROUND:In steroid-induced osteonecrosis, hypertrophy and hyperplasia of marrow fat cells and lipid deposition of osteocytes can be found in the femoral head. However, the precise reason is not clear yet. The aim of this study was to observe the effect of dexamethasone (Dex) on differentiation of marrow stromal cell...

journal_title：Chinese medical journal

authors： Yin L,Li YB,Wang YS

更新日期：2006-04-05 00:00:00

abstract：BACKGROUND:Interferon-gamma release assay (IGRA) has been used in latent tuberculosis (TB) infection and TB diagnosis, but the results from different high TB-endemic countries are different. The aim of this study was to investigate the value of IGRA in the diagnosis of active pulmonary TB (PTB) in China. METHODS:We co...

journal_title：Chinese medical journal

authors： Kang WL,Wang GR,Wu MY,Yang KY,Er-Tai A,Wu SC,Geng SJ,Li ZH,Li MW,Li L,Tang SJ

更新日期：2018-02-05 00:00:00

abstract：BACKGROUND:It is important to modulate the expression of glucocorticoids receptor (GR) in tress and maintain the immunity homeostasis in sepsis process. Rhubarb have been shown to have potential effects on anti-inflammatory and immune modulation. The present study was designed to investigate the effects of rhubarb on t...

journal_title：Chinese medical journal

authors： Liu J,Li G,Chen YZ,Zhang LD,Wang T,Wen ZL,Wang L,Chen DC

更新日期：2019-05-20 00:00:00

abstract：:To understand the mechanism of hemorrhage, coagulation and fibrinolysis in epidemic hemorrhagic fever (EHF), thrombin time (TT), prothrombin time (PT), fibrinogen (FIG), the platelet count (PLAT), plasminogen (PLG), antithrombin-III (AT-III), fibrin-fibrinogen degraded products (FDP) and platelet functions of aggregat...

journal_title：Chinese medical journal

authors： Xiang LB,Zhang ZY,Chen JM,Xiang JM,Cosgriff TM

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND:The most typical cardiac abnormality is conotruncal defects (CTDs) in patients with 22q11 deletion syndrome (22q11DS). HIRA (histone cell cycle regulator) gene, as one of the candidate genes located at the critical region of 22q11DS, was reported as possibly relevant to CTD in animal models. This study aimed...

journal_title：Chinese medical journal

authors： Ju ZR,Wang HJ,Ma XJ,Ma D,Huang GY

更新日期：2016-10-20 00:00:00

abstract：BACKGROUND:The patients with unprotected left main coronary artery (ULMCA) stenosis and chronic total occlusion (CTO) lesions at the left anterior descending (LAD) artery are often recommended for bypass surgery. However, some of these patients are deemed inoperable or are at high risk for surgery. In this study, we ex...

journal_title：Chinese medical journal

authors： Yang GT,Han YL,Jing QM,Wang SL,Li Y,Ma YY,Wang G,Luan B,Wang XZ,Wang B,Wang ZL,Wang DM

更新日期：2010-04-05 00:00:00

abstract：OBJECTIVE:To summarize the recent findings on the epidemiology of medically important, opportunistic invasive fungal infections (IFIs) in China and discuss the relevant social, economical reasons and medical factors. DATA SOURCES:We performed a comprehensive search of both English and Chinese literatures of opportunis...

journal_title：Chinese medical journal

authors： Liao Y,Chen M,Hartmann T,Yang RY,Liao WQ

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:This article aims to present a brief profile of the advances in prevention and treatment of myocardial injury in cancer therapy based on relevant literature or reports. DATA SOURCES:The data cited in this review were obtained from articles indexed in PubMed and China National Knowledge Internet (CNKI) up to ...

journal_title：Chinese medical journal

authors： Miao JX,Gao S,Fan L,Cao F

更新日期：2019-11-20 00:00:00

abstract：BACKGROUND:Thoracic endovascular aortic repair (TEVAR) is an emerging treatment modality, which has been rapidly embraced by clinicians treating thoracic aortic disease. However, the clinical manifestations of systemic inflammatory response after TEVAR as post-implantation syndrome (PIS) resemble the perioperative infe...

journal_title：Chinese medical journal

authors： Xue L,Luo S,Luo J,Liu Z,Gu M,Kang H,Yang F,Nie B,Liu Y,Huang W,Xie N,He P,Dong H,Ni Z,Fan R,Chen J

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Jaw osteonecrosis possibly associated with the administration of bisphosphonates is expected to be treated with a non-pharmacologic approach. This study aimed to determine whether noninvasive, mechanically mediated vibration would inhibit the decline in bone mineral density (BMD) that follows menopause, enha...

journal_title：Chinese medical journal

authors： Ruan XY,Jin FY,Liu YL,Peng ZL,Sun YG

更新日期：2008-07-05 00:00:00

abstract：Background:There was still conflict on the antithrombotic advantage of ticagrelor versus clopidogrel among East Asian population with acute coronary syndrome (ACS). We considered that the baseline bleeding risk might be an undetected key factor that significantly affected the efficacy of ticagrelor. Methods:A total of...

journal_title：Chinese medical journal

authors： Wang HY,Li Y,Xu XM,Li J,Han YL

更新日期：2018-09-05 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy and safety of misoprostol in term labour induction. DATA SOURCES:Data from published English and Chinese literatures about misoprostol in term labour induction were identified from Medline and CBMdisk (using the search terms "misoprostol" and "labour induction") before 2001; hand sea...

journal_title：Chinese medical journal

authors： Li XM,Wan J,Xu CF,Zhang Y,Fang L,Shi ZJ,Li K

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:Bone morphogenetic protein (BMP) is a member of the superfamily of transforming growth factor-beta. Recent studies show that it is an indispensable factor in hematopoiesis. To better characterize the effect of recombinant human BMP (rhBMP)-2 in hematopoiesis, we set out to determine whether rhBMP-2 could pro...

journal_title：Chinese medical journal

authors： Liu SB,Hu PZ,Hou Y,Li P,Cao W,Tian Q

更新日期：2009-04-05 00:00:00

abstract：OBJECTIVE:To investigate whether or not estrogen receptor and other sex hormone receptors are present in hemangioma tissues of children. METHODS:Fifty-two specimens of hemangiomas were taken from 52 children. The specimens were doubly stained with hematoxylin-eosin and enzyme-linking affinity immunohistochemistry. The...

journal_title：Chinese medical journal

authors： Lui W,Zhang S,Hu T,Wei F,Gao Y,Cheng N

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND:Receptor activator of nuclear factor kappa B (NF-κB) ligand (RANKL) and osteoprotegerin (OPG) have been recently shown to play important roles in bone resorption. The aim of this study was to investigate the possible association between the expression of bone resorption regulators (RANKL and OPG) and inflamm...

journal_title：Chinese medical journal

authors： Fan R,Sun B,Zhang CF,Lü YL,Xuan W,Wang QQ,Yin XZ

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Pancreatic cancer is a highly malignant tumor affecting an ever increasing number of patients with a mean 5-year survival rate below 4%. Therefore, gene therapy for cancer has become a potential novel therapeutic modality. In this study we sought to determine the inhibitory effects of adenovirus-mediated hum...

journal_title：Chinese medical journal

authors： Pan XT,Zhu QY,Li DC,Yang JC,Zhang ZX,Zhu XG,Zhao H

更新日期：2008-10-20 00:00:00

abstract：BACKGROUND:Tbx1 is the major candidate gene for DiGeorge syndrome (DGS). Similar to defects observed in DGS patients, the structures disrupted in Tbx1(-/-) animal models are derived from the neural crest cells during development. Although the morphological phenotypes of some Tbx1 knock-down animal models have been well...

journal_title：Chinese medical journal

authors： Zhang LF,Gui YH,Wang YX,Jiang Q,Song HY

更新日期：2010-05-05 00:00:00

abstract：OBJECTIVES:To formulate an equation for fine mapping of disease loci under complex conditions and determine the marker-disease distance in a specific case using this equation. METHODS:Lewontin's linkage disequilibrium (LD) measure D' was used to formulate an equation for mapping disease genes in the presence of phenoc...

journal_title：Chinese medical journal

authors： Gong G,Haynatzki G,Deng HW,Recker RR,Mordeson J,Cheng SC,Fong N

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND:Orthotopic liver transplantation (OLT) has become the therapeutic option of choice for end-stage liver disease. The aim of this study was to investigate the changes of splenic morphology, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), apparent diffusion coefficient (ADC) values and explore their...

journal_title：Chinese medical journal

authors： Wang J,Liang Y,Yan R,Jiang Z,Liu J,Hu B,He B,Ren L,Chen J,Shan H

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To understand whether very low density lipoprotein (VLDL) and oxidatively modified very low density lipoprotein (OX-VLDL) can stimulate vascular smooth muscle cells (SMCs) to express high level of monocyte chemotactic protein (MCP-1) mRNA. METHODS:LDL and VLDL were isolated from normal blood donors by densit...

journal_title：Chinese medical journal

authors： Ruan Q,Deng Z,Song J

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:Hospital-acquired pneumonia (HAP) is the most common hospital-acquired infection in China with substantial morbidity and mortality. But no specific risk assessment model has been well validated in patients with HAP. The aim of this study was to investigate the published risk assessment models that could pote...

journal_title：Chinese medical journal

authors： Wen JN,Li N,Guo CX,Shen N,He B

更新日期：2020-12-03 00:00:00

abstract：:Cellular and humoral immune functions in Chinese hemophiliacs with and without human immunodeficiency virus (HIV) infection were compared with those of healthy controls. There was a significant increase in peripheral T8 cells and a significant decrease of peripheral T4 cells as well as the T4/T8 ratio in 3 hemophiliac...

journal_title：Chinese medical journal

authors： Tang DJ,Pang XG

更新日期：1991-10-01 00:00:00

abstract：OBJECTIVES:To study the status of cochlear mitochondrial DNA (mtDNA) and to determine the location of mtDNA deletion in aged mice. METHODS:We detected cochlear mtDNA in 2, 7 - 10 and 17 - 19 month old mice by nested polymerase chain reaction (PCR) and DNA sequencing. RESULTS:mtDNA3867bp deletions were found in the co...

journal_title：Chinese medical journal

authors： Zhang X,Han D,Ding D,Dai P,Yang W,Jiang S,Salvi RJ

更新日期：2002-09-01 00:00:00

abstract：OBJECTIVE:To study the preventive effect of artemether (Art) in protecting the people from schistosome infection during flood fighting in schistosomiasis endemic area of Poyang Lake, Jiangxi Province. METHODS:From mid July to mid August in 1996, the water level in Poyang Lake rose due to torrential rains and 2 embankm...

journal_title：Chinese medical journal

authors： Song Y,Xiao S,Wu W,Zhang S,Xie H,Xu X,Hu X,Cui Q,Chen M,Zheng J

更新日期：1998-02-01 00:00:00

abstract：OBJECTIVE:To explore the methods of lens-sparing (without lensectomy), non-silicone oil tamponade and no scleral buckling for treatment of early giant retinal tears. METHODS:Thirteen cases of early retinal detachment of proliferative vitreoretinopathy (PVR) grade C2-D1, with giant tear extending from 135 degrees to 27...

journal_title：Chinese medical journal

authors： Xu X,Zhang X,Wu N,Ho PC

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:Frozen-thawed embryo transfer (FET) is the most common way to prevent serious late ovarian hyperstimulation syndrome and increase the cumulative pregnancy rate. We evaluated the effectiveness of an FET program for improving the embryo implantation and clinical pregnancy rates, and ultimate embryo utilization...

journal_title：Chinese medical journal

authors： Zhou F,Lin XN,Tong XM,Li C,Liu L,Jin XY,Zhu HY,Zhang SY

更新日期：2009-09-05 00:00:00

abstract：:Plasma levels of tissue plasminogen activator (tPA) antigen, tPA activity and plasminogen activator inhibitor (PAI) activity were determined in 40 cases of acute myocardial infarction (AMI) at the onset and 2-4 weeks after the onset of the disease. 24 healthy subjects served as controls. At the onset of AMI, mean plas...

journal_title：Chinese medical journal

authors： Chen HZ,Jia HY,Song HY,Wang JY

更新日期：1990-07-01 00:00:00

abstract：:Immunohistochemical and ultrastructural findings in a primary intracranial endodermal sinus tumor are reported in this paper. The tumor cells exhibited AFP, CEA and anti-alpha-1-trypsin positive immunoreactivity immunocytochemically. Aggregates of electron-dense material in the extra- and intracellular spaces and amor...

journal_title：Chinese medical journal

authors： Shi QL,Jin XZ,Zhou XJ,Qian YC,Shi Q

更新日期：1991-06-01 00:00:00