Effect of recombinant adenovirus vector mediated human interleukin-24 gene transfection on pancreatic carcinoma growth.

abstract：OBJECTIVE:To investigate the correlation among retinal fluorescein angiography, blood viscosity, and other factors in patients with open angle glaucoma (POAG). METHODS:Multiple step regression analysis was made to investigate the correlation between each of the following blood vessel filling times: the arm-choroid (A-...

journal_title：Chinese medical journal

authors： Liu X,Zhou W,Ye T,Ge J,Cai X,Cheng A,Lin Y,Liang L,Tang H,Chen Z

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:Screening for amblyopia at earliest is important for early treatment and better prognosis. This study aimed to evaluate the validity of uncorrected distant and near visual acuity (VA) and stereoacuity for screening amblyopia in grade-1 students in primary school in central China. METHODS:By stratified clust...

journal_title：Chinese medical journal

authors： Fu J,Li SM,Li JL,Li SY,Liu LR,Wang Y,Li H,Zhu BD,Ji YZ,Yang Z,Li L,Chen W,Wang NL,g Childhood Eye Study Group.

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Prediabetes is an early stage of β-cell dysfunction presenting as insulin resistance. Evidences suggest that endoplasmic reticulum (ER) stress is involved in the pathogenesis of type 2 diabetes mellitus and prediabetes. In a Chinese population with prediabetes, we investigated single nucleotide polymorphisms...

journal_title：Chinese medical journal

authors： Feng N,Ma X,Wei X,Zhang J,Dong A,Jin M,Zhang H,Guo X

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Some individuals have multiple renal arteries. Severe stenosis in one of the arteries may cause refractory hypertension. The detection of stenosis within one of the multiple renal arteries usually required invasive procedures, such as computed tomographic angiography (CTA) and magnetic resonance angiography ...

journal_title：Chinese medical journal

authors： Qin W,Zhang X,Yang M,Zhong XH,Zhao MH

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVE:To observe the long-term follow-up of 72 patients with transient ischemic attack (TIA) and evaluate the clinical significance of neurovascular surgical indication. METHODS:Seventy-two patients with TIA collected from years 1959 to 1977 were followed up by means of face-to-face communication with the patients...

journal_title：Chinese medical journal

authors： Gong T,Wang X

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:The Medtronic InSync Sentry is the first available cardiac resynchronization therapy defibrillator (CRT-D) which can monitor fluid status by measuring intrathoracic impedance. This study was designed to observe the effectiveness of intrathoracic impedance monitoring on detecting aggravation of heart failure....

journal_title：Chinese medical journal

authors： Qiao Q,Hua W,Ding LG,Chen KP,Wang J,Wang FZ,Zhang S

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVE:To investigate the antitumor immune efficiency of mouse dendritic cells (mDCs) by using adenovirus-mediated tumor necrosis factor-alpha (AdV-TNF-alpha) gene transfer. METHODS:MDCs infected with AdV-TNF-alpha and AdV-pLpA (no gene insert) at 100 multiplicity of infection (MOI) were analyzed by RNase protectio...

journal_title：Chinese medical journal

authors： Zhang W,Yang H,Wang Z,Jim X

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:Aquaporin-1 (AQP1) has involved in fluid transport in diverse pulmonary edema diseases. Our study aimed to explore the dynamic changes of AQP1 in pulmonary water metabolism in rats following traumatic brain injury (TBI) and the protective effect provided by shenmai injection. METHODS:Sixty male Sprague Dawl...

journal_title：Chinese medical journal

authors： Bai Y,Yao HX,Hu ML,Wang LR,Jin LD,Wang WT,Lin LN

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Previous studies demonstrated general anesthetics affect potassium ion channels, which may be one of the mechanisms of general anesthesia. Because the effect of etomidate on potassium channels in rat hippocampus which is involved in memory function has not been studied, we investigated the effects of etomida...

journal_title：Chinese medical journal

authors： Tan HY,Sun LN,Wang XL,Ye TH

更新日期：2010-03-20 00:00:00

abstract：BACKGROUND:The Ras/Raf/ERK1/2 signaling pathway controls many cellular responses such as cell proliferation, migration, differentiation, and death. In the nervous system, emerging evidence also points to a death-promoting role for ERK1/2 in both in vitro and in vivo models of neuronal death. To further investigate how ...

journal_title：Chinese medical journal

authors： Cao FJ,Zhang X,Liu T,Li XW,Malik M,Feng SQ

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Glaucoma is mainly characterized by the loss of retinal ganglion cells. Ciliary neurotrophic factor (CNTF) is believed to stimulate the regeneration of axons of retinal ganglion cells. The objective of our study was to detect the expression of CNTF in the retina of a rat glaucoma model with increased intraoc...

journal_title：Chinese medical journal

authors： Wu Q,Zhang M,Song BW,Lu B,Hu P

更新日期：2007-10-20 00:00:00

abstract：BACKGROUND:Low molecular weight heparin (LMWH), as one of anticoagulant drugs, has been used for the treatment of chronic obstructive pulmonary disease (COPD) with prethrombotic state, but the specific use time is unclear. The aim of the study is to observe the effect of LMWH at two different periods of prethrombotic s...

journal_title：Chinese medical journal

authors： Wang Y,Sun N,Cheng Z,Tong L

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Cochlear implants (CIs) can improve speech recognition for children with severe congenital hearing loss, and open-set word recognition is an important efficacy measure. This study examined Mandarin open-set word recognition development among Chinese children with CIs and normal hearing (NH). METHODS:This st...

journal_title：Chinese medical journal

authors： Kong Y,Liu X,Liu S,Li YX

更新日期：2017-10-20 00:00:00

abstract：:The long-term results of total meniscectomy in 60 patients were reviewed. The patients were followed up to 10 to 33 years. 58.3% of the patients had excellent or good results. Statistical analysis showed that the late results were related to the time of follow-up and not associated with the duration of disease before ...

journal_title：Chinese medical journal

authors： Dai L,Zhang W,Zhou Z,Xu Y

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND:The second-trimester maternal serum screening in twin pregnancy is still controversial, as the serum marker levels in twins are not as clear as those in singletons. This study aimed to evaluate the relationship between the levels of the second-trimester maternal serum free beta-human chorionic gonadotropin (...

journal_title：Chinese medical journal

authors： Zheng MM,Hu YL,Zhang CY,Ru T,Liu QL,Xu BY,Chen QG,Xu ZF,Zhang Y,Zhong XL

更新日期：2010-03-05 00:00:00

abstract：BACKGROUND:Human epididymis secretory protein 4 (HE4) is a new ovarian cancer biomarker. The factors influencing HE4 levels are not clear, and the reference data in China are limited. Here, we aim to evaluate the effects of menopause and age on HE4 levels and to provide a possible reference value for HE4 in healthy Chi...

journal_title：Chinese medical journal

authors： Cheng HY,Zeng L,Ye X,Ma RQ,Tang ZJ,Chu HL,Zhao YM,Zhu LR,Gao YN,Chang XH,Cui H

更新日期：2020-06-05 00:00:00

abstract：BACKGROUND:Over 70% of the total tissue weight in the cartilage matrix consists of water, and the early-stage osteoarthritic cartilage is characterized by swelling. Water transport in the cartilage matrix and across the membranes of chondrocytes may be important in normal and pathological conditions of cartilage. The p...

journal_title：Chinese medical journal

authors： Meng JH,Ma XC,Li ZM,Wu DC

更新日期：2007-12-20 00:00:00

abstract：BACKGROUND:A five-year follow-up study of intensive multifactorial intervention was undertaken to assess the changes of circulating serum amyloid A (SAA) levels and the incidence of atherosclerosis (AS) in patients with short-duration type 2 diabetes mellitus (T2DM) without macroangiopathy, and whether intensive multif...

journal_title：Chinese medical journal

authors： Du JL,Liu JF,Men LL,Yao JJ,Sun LP,Sun GH,Song GR,Yang Y,Bai R,Xing Q,Li CC,Sun CK

更新日期：2009-11-05 00:00:00

abstract：: ...

journal_title：Chinese medical journal

authors： Zeng XX,Liu J,Ma L,Fu P

更新日期：2018-11-20 00:00:00

abstract：OBJECTIVE:To explore the effects of thyroid hormone (TH) on cardiac function and peripheral lymphocyte beta-adrenoceptors (beta-ARs) of patients with chronic congestive heart failure (CHF). METHODS:Twenty-eight patients with class III or IV advanced CHF due to dilated cardiomyopathy (DCM) or ischemic cardiomyopathy (I...

journal_title：Chinese medical journal

authors： Lu X,Huang J,Zhang X,Li X,Wang C,Zhang P,Chen Y

更新日期：2003-11-01 00:00:00

abstract：:Endolymphatic sac papillary tumor (ELST) is an extremely rare and aggressive tumor characterized by hearing loss and temporal bone destruction. A case with clinical, imaging, pathologic and treatment data is reported and relevant literature is reviewed. A 25-year-old woman, with ELST underwent craniotomy for tumor sub...

journal_title：Chinese medical journal

authors： Yu SJ,Chen YD,Gao F,Qiu XG,Chang H

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:The development of new adjuvants for human use has been the focus of attention. This study's aim is to explore the possibility of using nanoparticle Ca nanoparticles (CA) as a vaccine adjuvant of anti-idiotypic antibody NP30 against schistosomiasis and its protective mechanisms. METHODS:Nanoparticle CA-NP30...

journal_title：Chinese medical journal

authors： Feng ZQ,Zhong SG,Li YH,Li YQ,Qiu ZN,Wang ZM,Li J,Dong L,Guan XH

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Irritable bowel syndrome (IBS) is reported associated with the alteration of gut microbial composition termed as dysbiosis. However, the pathogenic mechanism of IBS remains unclear, while the studies of Chinese individuals are scarce. This study aimed to understand the concept of dysbiosis among patients wit...

journal_title：Chinese medical journal

authors： Wang Z,Xu CM,Liu YX,Wang XQ,Zhang L,Li M,Zhu SW,Xie ZJ,Wang PH,Duan LP,Zhu HQ

更新日期：2019-04-20 00:00:00

abstract：OBJECTIVE:Parkinson's disease (PD) is featured with motor disorder and nonmotor manifestations including psychological symptoms, autonomic nervous system dysfunction, and paresthesia, which results in great inconvenience to the patients' life. The apolipoprotein (Apo) superfamily, as a group of potentially modifiable b...

journal_title：Chinese medical journal

authors： Li L,Liu MS,Li GQ,Tang J,Liao Y,Zheng Y,Guo TL,Kang X,Yuan MT

更新日期：2017-11-05 00:00:00

abstract：OBJECTIVE:To study the cellular mechanism of the effect of Ang II on ICa,L in single guinea-pig ventricular cells by using losartan and 1-(5-lsoquinolinylsulfonyl)-2-Methyl-Piperazine (H-7) as the Ang II type 1 receptor (AT1) inhibitor and protein kinase C inhibitor, respectively. METHODS:Patch clamp techniques were u...

journal_title：Chinese medical journal

authors： Yang X,Hui J,Jiang W

更新日期：2001-06-01 00:00:00

abstract：OBJECTIVE:To investigate the localization of Ca(2+)-ATPase (Ca(2+) pump) in the cochlear and its change after endolymphatic hydrops, and to study the relationship between compound action potential (CAP) threshold and the Ca(2+)-ATPase activety. METHODS:The left endolymphatic sac was ablated to induce endolymphatic hyd...

journal_title：Chinese medical journal

authors： Zhang S,Yang W,Sun J,Zhao C,Zhou N

更新日期：2002-08-01 00:00:00

abstract：:Lectin binding patterns in psoriasis, lichen planus and seborrheic keratosis lesions were studied using 14 different biotinyl lectins and avidin-horseradish peroxidase. Compared with normal epidermis, there were significant quantitative and qualitative differences, some of which were characteristic. ...

journal_title：Chinese medical journal

authors： Gao MY,Lin XR,Miao Q

更新日期：1992-12-01 00:00:00

abstract：OBJECTIVE:To develop a diagnostic framework that would help defining clinical problems by the expanded understanding with traditional Chinese medicine (C Med) and western medicine (W Med). METHODS:The basic attributes of diagnosis and the use of diagnostic techniques of W Med and C Med are reviewed. Some of the variou...

journal_title：Chinese medical journal

authors： Yu EC

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND:With aging, the human fracture risks gradually increase. This is mainly due to the corresponding changes of the biomechanical parameters of human bone presents with aging. We measured the microstructural parameters of lumbar bone from women in several age groups by micro-computed tomography and scanning elec...

journal_title：Chinese medical journal

authors： Jiang R,Liu GM,Bai HT,Wang TB,Wu H,Jia YY,Luo YG

更新日期：2013-10-01 00:00:00

abstract：:This study demonstrates that there are distinct abnormalities of vitamin D and calcium metabolism in children with nephrotic syndrome (NS) and normal renal function. In patients with active NS, serum calcium, ionized calcium, 25-OHD3 and CT were decreased, plasma PTH level was increased and serum ALP was elevated. The...

journal_title：Chinese medical journal

authors： Huang JP,Bai KM,Wang BL

更新日期：1992-10-01 00:00:00