Changes in Ca2+-ATPase in a guinea pig endolymphatic hydrops model.

abstract：:Human keratinocytes in primary culture stimulated by Ca2+ ionophore A23187(Io) could synthesize and release a material which might aggregate aspirin-treated washed rabbit platelets and was identified as platelet activating factor (PAF) by four methods. Io stimulated the production of PAF by keratinocytes in a time- an...

journal_title：Chinese medical journal

authors： Liu BJ,Zheng MR,Zhang SZ,Dai FP

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:In a previous study, we demonstrated that ephrin-A2 and -A3 negatively regulate the growth of neural progenitor cells in the central nervous system. Adult mice deficient in ephrin-A2 and -A3 (A2(-/-)A3(-/-)) displayed active ongoing neurogenesis throughout the brain, and mice deficient in ephrin-A3 alone sho...

journal_title：Chinese medical journal

authors： Zhu R,Cho KS,Chen DF,Yang L

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:One of the reasons for poor neuroregeneration after central nervous system injury is the presence of inhibitory factors such as Nogo. Here, we tested the inhibition of Nogo by RNA interference both in vitro and in vivo, using recombinant adenovirus-mediated transfection of short hairpin RNAs, to explore a ne...

journal_title：Chinese medical journal

authors： Sun HH,Gao F,Liu B,Yu HT,Kong N,Liu GM

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Collagen VI-related myopathies are autosomal dominant and recessive hereditary myopathies, mainly including Ullrich congenital muscular dystrophy (UCMD) and Bethlem myopathy (BM). Muscle magnetic resonance imaging (MRI) has been widely used to diagnosis muscular disorders. The purpose of this study was to ev...

journal_title：Chinese medical journal

authors： Fu J,Zheng YM,Jin SQ,Yi JF,Liu XJ,Lyn H,Wang ZX,Zhang W,Xiao JX,Yuan Y

更新日期：2016-08-05 00:00:00

abstract：:Renal angiomyolipoma is a type of benign tumor that occurs sporadically in addition to being associated with tuberous sclerosis. Preoperative embolization of large tumors is important to avoid excessive blood loss during surgery. We reported a patient with a 5505-g giant renal angiomyolipoma in a solitary kidney. The ...

journal_title：Chinese medical journal

authors： Shen WH,Pan JH,Yan JN,Chen ZW,Zhou ZS,Lu GS,Li WB

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Leber congenital amaurosis (LCA) is a visual disease which is caused by RPE65 mutations and results in retinal degeneration and severe vision loss in early infancy. According to previous researches, mutations of the RPE65 gene account for 16% of all cases of LCA. This study aimed to identify RPE65 gene mutat...

journal_title：Chinese medical journal

authors： Liu J,Bu J

更新日期：2017-11-20 00:00:00

abstract：OBJECTIVE:To investigate the prevalence and features of active human cytomegalovirus (HCMV) infection in children with systemic lupus erythematosus (SLE) and evaluate the diagnostic value of the HCMV using antigenemia assay, serum polymerase chain reaction (PCR) and serology test. METHODS:Twenty-one SLE children under...

journal_title：Chinese medical journal

authors： Zhang C,Shen K,Jiang Z,He X

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:Cerebral ischemia-reperfusion injury is the main reason for the loss of neurons in the ischemic cerebrovascular disease. Therefore, to deeply understand its pathogenesis and find a new target is the key issue to be solved. This research aimed to investigate the neuroprotective effects of salvianolic acid B (...

journal_title：Chinese medical journal

authors： Wang Y,Jiang YF,Huang QF,Ge GL,Cui W

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:C-arm-based flat-panel detector cone-beam computed tomography (CBCT) venography has never been used in the management of iliac vein compression syndrome (IVCS). This study aimed to determine the technical feasibility and safety of CBCT venography in the diagnosis of IVCS compared with conventional venography...

journal_title：Chinese medical journal

authors： Wang CM,Zhang WL,Li X

更新日期：2020-08-26 00:00:00

abstract：BACKGROUND:Generalized glucocorticoid resistance syndrome is a rare familial or sporadic condition characterized by generalized, partial, target-tissue insensitivity to glucocorticoids. This syndrome is partially caused by mutations in the human glucocorticoid receptor (hGR) gene. The clinical spectrum of generalized g...

journal_title：Chinese medical journal

authors： Zhu HJ,Dai YF,Wang O,Li M,Lu L,Zhao WG,Xing XP,Pan H,Li NS,Gong FY

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Immune cells within a tumor microenvironment have shown modulatory effects on tumor angiogenic activity. Renal cell carcinoma (RCC) is a hypervascular tumor that reportedly increases the frequency of regulatory T cells (Tregs) in tumor tissues. This study investigated the correlation between Tregs infiltrati...

journal_title：Chinese medical journal

authors： Ning H,Shao QQ,Ding KJ,Gao DX,Lu QL,Cao QW,Niu ZH,Fu Q,Zhang CH,Qu X,Lü JJ

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:To review the current research into Foxp3(+) regulatory T cells (Treg) cell surface molecules, plasticity of Treg cells and mechanisms of Treg cell suppression and to explore the possibilities to interfere in Treg cell suppression of anti-tumor immunity. DATA SOURCES:A literature search of all English articl...

journal_title：Chinese medical journal

authors： Feng LL,Wang X

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:There are controversies about the use of artificial colloids. This research was aimed to determine the effect of various artificial colloids on blood coagulation in the shock stage of severe burn injury. METHODS:Totally, 18 female Ba-Ma mini-pigs were subjected to a 40% total body surface third-degree flame...

journal_title：Chinese medical journal

authors： Zhou JJ,Xing N,Chen J,Shi JW,Su GL

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Few clinical studies or randomized clinical trial results have reported the impact of fast track surgery on postoperative insulin sensitivity. This study aimed to investigate the effects of fast track surgery on postoperative insulin sensitivity in patients undergoing elective open colorectal resection. MET...

journal_title：Chinese medical journal

authors： Yang DJ,Zhang S,He WL,Chen HY,Cai SR,Chen CQ,Song XM,Cui J,Ma JP,Zhang CH,He YL

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Postoperative preablative stimulated thyroglobulin (ps-Tg) has been evaluated in predicting prognosis and success of ablation regarding differentiated thyroid cancer (DTC); however, its relationship with recurrence risk and radioiodine decision-making remains uncertain, especially in Chinese DTC patients. We...

journal_title：Chinese medical journal

authors： Yang X,Liang J,Li TJ,Yang K,Liang DQ,Yu Z,Lin YS

更新日期：2015-04-20 00:00:00

abstract：BACKGROUND:Endovenous laser ablation (EVLA) is an improved method to treat varicose great saphenous veins (GSV) with a high satisfactory rate. This study aimed to evaluate the efficiency and safety of treatment by EVLA procedures with ultrasound-guided perivenous tumescence. METHODS:Thirty-one patients (31 limbs) with...

journal_title：Chinese medical journal

authors： Chen JQ,Xie H,Deng HY,Yuan K,Zhang JW,Zhang H,Zhang L

更新日期：2013-02-01 00:00:00

abstract：:Enhanced recovery after cesarean (ERAC) delivery is an evidence-based, multi-disciplinary approach throughout pre-, intra-, post-operative period. The ultimate goal of ERAC is to enhance recovery and improve the maternal and neonatal outcomes. This review highlights the role of anesthesiologist in ERAC protocols. This...

journal_title：Chinese medical journal

authors： Liu ZQ,Du WJ,Yao SL

更新日期：2020-03-05 00:00:00

abstract：OBJECTIVE:To analyse the relationship between age and treatment with captopril after acute myocardial infarction (AMI). METHODS:In a randomized trial, 822 patients with a first AMI received conventional medical treatment, including intravenous thrombolytic therapy and oral aspirin or metoprolol, and then were randomly...

journal_title：Chinese medical journal

authors： Cai X,Shen W,Gong L

更新日期：2001-07-01 00:00:00

abstract：:This is China's pilot study in the assessment of the diagnostic value of serum soluble IL-2 receptor (sIL-2R) in gastric cancer. We measured its level by ELISA method in 45 patients with gastric cancer (without metastasis: 32; with metastasis: 5; recurrence: 8) 27 gastric ulcer, 27 superficial gastritis and 44 healthy...

journal_title：Chinese medical journal

authors： Wang YF,Wu XN,Zhou YH,Chen XF,Shen J,Wang HJ

更新日期：1994-04-01 00:00:00

abstract：:Diabetes mellitus and pancreatic ductal adenocarcinoma are two common diseases worldwidely which are both derived from different components of pancreas. The pancreatic and duodenal homeobox-1 (PDX1) is an essential transcription factor for the early development of pancreas that is required for the differentiation of a...

journal_title：Chinese medical journal

authors： Tang ZC,Chu Y,Tan YY,Li J,Gao S

更新日期：2020-02-05 00:00:00

abstract：OBJECTIVE:To investigate the status of the drug resistance and the ampC gene expression of Enterobacter cloacae. METHODS:Disk diffusion tests were made for detecting the susceptibility of antimicrobial agents against Enterobacter cloacae. AmpC gene was amplified by polymerase chain reaction (PCR) and verified by DNA s...

journal_title：Chinese medical journal

authors： Zhou Z,Li L,Yu Y,Ma Y

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Severe acute respiratory syndrome (SARS) is a disease with a mortality of 9.56%. Although SARS is etiologically linked to a new coronavirus (SARS-CoV) and functional cell receptor has been identified, the pathogenesis of the virus infection is largely unclear. METHODS:The clinical specimens were processed a...

journal_title：Chinese medical journal

authors： He WP,Shu CL,Li BA,Zhao J,Cheng Y

更新日期：2008-04-05 00:00:00

abstract：BACKGROUND:The evoked electromyography (EMG) is frequently used to identify facial nerve in order to prevent its damage during surgeries. Partial neuromuscular blockade (NMB) has been suggested to favor EMG activity and insure patients' safety. The aim of this study was to determine an adequate level of NMB corresponde...

journal_title：Chinese medical journal

authors： Cai YR,Xu J,Chen LH,Chi FL

更新日期：2009-02-05 00:00:00

abstract：BACKGROUND:Now lung volume reduction surgery (LVRS) has become one of the most effective methods for the management of some cases of severe chronic obstructive pulmonary disease (COPD). We evaluated the mid-term effects of LVRS on pulmonary function in patients with severe COPD. METHODS:Ten male patients with severe C...

journal_title：Chinese medical journal

authors： Liu JM,Yang WL,Jiang GN,Ding JA,Zheng W,Liu WZ,Wang YM,Gao BL,Jiang P,Wu W,Li X,Bjorn J

更新日期：2007-04-20 00:00:00

abstract：BACKGROUND:Some patients with pelvic organ prolapse may suffer from lower urinary tract symptoms (LUTS), especially stress urinary incontinence (SUI) named de novo SUI after pelvic floor reconstruction. This study aimed to investigate the incidence and risk factors of de novo SUI. METHODS:This is a nested case-control...

journal_title：Chinese medical journal

authors： Wang SY,Cao TT,Wang RZ,Yang X,Sun XL,Wang JL

更新日期：2017-03-20 00:00:00

abstract：BACKGROUND:Therapeutic angiogenesis has been shown to promote blood vessel growth and improve tissue perfusion. Vascular endothelial growth factor (VEGF) plays an important role in angiogenesis. However, it has side effects that limit its therapeutic utility in vivo, especially at high concentrations. This study aimed ...

journal_title：Chinese medical journal

authors： Diao Y,Lian L,Guo L,Chen H,Chen Y,Song X,Li Y

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:With the technical advances, magnetic resonance imaging (MRI) is now sensitive enough to detect subtle structural abnormalities of ocular motor nerves arising from the brainstem and orbits of living subjects. This study was designed to delineate the MRI characteristics in patients with special forms of strab...

journal_title：Chinese medical journal

authors： Jiao YH,Zhao KX,Wang ZC,Qian XH,Wu X,Man FY,Lu W,She HC

更新日期：2009-12-20 00:00:00

abstract：:Thallium-201 dipyridamole test (Tl-201DT) has high sensitivity and specificity in the assessment of coronary disease (CAD), but is not always available. We proposed impedance cardiography DT (IDT)instead. To determine the characteristic changes of impedance cardiogram (ICG) in patients with typical angina and to compa...

journal_title：Chinese medical journal

authors： Chen G,Mao HY,Wei KQ,Zhang DC,Guo QG

更新日期：1989-02-01 00:00:00

abstract：BACKGROUND:Multiple neonatal characteristics and adult cardiovascular risk factors are associated with the development of atherosclerosis, however little conclusive evidence exists characterizing the relative strength of these factors. In a large retrospective study, we investigated the association between both objecti...

journal_title：Chinese medical journal

authors： Lin X,Zhu WL,Tan L,Xu T,Xu RY,Fang Q,Zhang SY,Zhang ZX

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Survivin is an oncoprotein silenced in normal mature tissues but reactivated in serous ovarian cancer (SOC). Although transcriptional activation is assumed for its overexpression, the long 3'-untranslated region (3'-UTR) in survivin gene, which contains many alternate polyadenylation (APA) sites, implies a p...

journal_title：Chinese medical journal

authors： He XJ,Zhang Q,Ma LP,Li N,Chang XH,Zhang YJ

更新日期：2016-05-20 00:00:00