TNF-alpha gene-modified dendritic cells act as more potent adjuvants for peptide delivery to induce specific antitumor immunity in mice.

abstract：OBJECTIVE:To investigate osteoclastic resorption in trabeculae of osteoporotic femoral head. METHODS:Osteoporotic femoral heads were collected from 7 aged women with an average age of 72.4 years, who underwent endoprosthetic replacement for intracapsular hip fracture. Femoral head trabeculae from 3 young adults killed...

journal_title：Chinese medical journal

authors： Chai B,Tang X,Zhou W,Li H

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND:The postremission therapies for adult patients generally contain consolidation chemotherapy, allogeneic hematopoietic stem cell transplantation and autologous hematopoietic stem cell transplantation (auto-HSCT). Because of the various results from different centers, the optimal therapy for adult acute lympho...

journal_title：Chinese medical journal

authors： Ding Z,Han MZ,Chen SL,Ma QL,Wei JL,Pang AM,Zhang XY,Liang C,Yao JF,Cao YG,Feng SZ,Jiang EL

更新日期：2015-08-05 00:00:00

abstract：BACKGROUND:Robotic assisted minimally invasive cardiac sugery is a new technique that uses small port sites and peripheral vessel cannulation for cardiopulmonary bypass (CPB) has been used. The right internal jugular vein (IJV) is commonly used for intraoperative venous access to the central circulation and identified ...

journal_title：Chinese medical journal

authors： Wang Y,Wang G,Gao CQ

更新日期：2013-07-01 00:00:00

abstract：:An epidemiological study on the incidence and prevalence of Parkinson's disease (PD) was carried out in 29 provinces, cities and autonomous regions in this country in 1986. The survey was conducted in 117 areas, and 566 patients with PD were found among 3,869,162 persons examined, giving a point prevalence for men and...

journal_title：Chinese medical journal

authors： Wang YS,Shi YM,Wu ZY,He YX,Zhang BZ

更新日期：1991-11-01 00:00:00

abstract：BACKGROUND:Tumor has an ability to become enriched in mesenchymal stem cells (MSCs) and of guiding MSCs to migrate to tumor tissue. But there are lack of relevant reports on the distribution and differentiation of MSCs in tumor tissue and the effect on tumor growth after MSCs engrafted in tumor tissue. In this study, w...

journal_title：Chinese medical journal

authors： Zhao HF,Chen J,Xu ZS,Zhang KQ

更新日期：2009-03-20 00:00:00

abstract：BACKGROUND:Coexistent carotid and coronary artery diseases are common and patients with them remain at a high risk for perioperative stroke or myocardial infarction after coronary bypass surgery. The aim of this study was to investigate the effect of combined carotid endarterectomy (CEA) and off-pump coronary artery by...

journal_title：Chinese medical journal

authors： Chen XJ,Chen X,Xie DH,Shi KH,Xu M

更新日期：2009-12-20 00:00:00

abstract：OBJECTIVE:To observe the immediate angiographic and intravascular ultrasound (IVUS) results and their effects on one month clinical outcomes in forty-one patients who submitted to coronary stent deployment with IVUS guidance. METHODS:All patients were allocated to coronary stent implantation with high inflation pressu...

journal_title：Chinese medical journal

authors： Zhang D,Cai X,Shen W,Schiele F,Bassand JP

更新日期：2001-03-01 00:00:00

abstract：:An outbreak of viral central nervous system infection occurred from May to September, 1991 in Shanghai, China. Totally 376 cases were admitted into our hospital, 54% with encephalitis and 46% with meningoencephalitis. Echovirus type 30 was isolated from CSF and stools of the patients. Only 3 of the patients were under...

journal_title：Chinese medical journal

authors： Wang DM,Zhao GC,Zhuang SM,Zhang YC

更新日期：1993-10-01 00:00:00

abstract：BACKGROUND:Intravertebral and general anesthesia (GA) are two main anesthesia approaches but both have defects. This study was aimed to evaluate the effect of subarachnoid anesthesia combined with propofol target-controlled infusion (TCI) on blood loss and transfusion for total hip arthroplasty (THA) in elderly patient...

journal_title：Chinese medical journal

authors： Xu CS,Qu XD,Qu ZJ,Wang G,Wang HJ

更新日期：2020-03-20 00:00:00

abstract：BACKGROUND:The effects of near-road pollution on lung function in China have not been well studied. We aimed to investigate the effects of long-term exposure to traffic-related air pollution on lung function, airway inflammation, and respiratory symptoms. METHODS:We enrolled 1003 residents aged 57.96 ± 8.99 years livi...

journal_title：Chinese medical journal

authors： Hu ZW,Zhao YN,Cheng Y,Guo CY,Wang X,Li N,Liu JQ,Kang H,Xia GG,Hu P,Zhang PJ,Ma J,Liu Y,Zhang C,Su L,Wang GF

更新日期：2016-09-20 00:00:00

abstract：OBJECTIVE:To investigate the regulation effect of protein kinase ERK on the activation of transcription factor STAT3 in response to IL-6 in the Sko-007 human myeloma cell line. METHODS:Electrophoretic mobility shift assay (EMSA) and immunoprecipitation (IP) were used to show the activation of STAT3 and ERK in Sko-007 ...

journal_title：Chinese medical journal

authors： Song L,Shen B,Li Y

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:It is important to modulate the expression of glucocorticoids receptor (GR) in tress and maintain the immunity homeostasis in sepsis process. Rhubarb have been shown to have potential effects on anti-inflammatory and immune modulation. The present study was designed to investigate the effects of rhubarb on t...

journal_title：Chinese medical journal

authors： Liu J,Li G,Chen YZ,Zhang LD,Wang T,Wen ZL,Wang L,Chen DC

更新日期：2019-05-20 00:00:00

abstract：Background:Facioscapulohumeral muscular dystrophy (FSHD) is characterized by asymmetric muscular deficit of facial, shoulder-girdle muscles, and descending to lower limb muscles, but it exists in several extramuscular manifestations or overlapping syndromes. Herein, we report a "complex disease plus" patient with FSHD1...

journal_title：Chinese medical journal

authors： Lin XD,He JJ,Lin F,Chen HZ,Xu LQ,Hu W,Cai NQ,Lin MT,Wang N,Wang ZQ,Xu GR

更新日期：2018-09-20 00:00:00

abstract：OBJECTIVE:To review the development of T follicular helper (TFH) cells and their role in systemic lupus erythematosus (SLE) pathogenesis, the effect of dendritic cells (DCs) on TFH cells in SLE, as well as the potential use of TFH cells as a new therapeutic target in clinical practice. DATA SOURCES:The data used in th...

journal_title：Chinese medical journal

authors： Ma H,Wan S,Xia C

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Previous studies demonstrated that vagus nerve stimulation (VNS) is an effective therapy for drug-resistant epilepsy. Acupuncture is also used to treat epilepsy. This study was designed to examine the safety and effectiveness of transcutaneous auricular vagus nerve stimulation (ta-VNS) for patients with drug...

journal_title：Chinese medical journal

authors： Rong P,Liu A,Zhang J,Wang Y,Yang A,Li L,Ben H,Li L,Liu R,He W,Liu H,Huang F,Li X,Wu P,Zhu B

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Hepatoid adenocarcinoma of the stomach (HAS) is a rare type of gastric carcinoma, which has its unique clinicopathological features and poorer prognosis than that of the ordinary gastric adenocarcinoma. At present, there is still a lack of understanding about this disease. The current study aimed to summariz...

journal_title：Chinese medical journal

authors： Zhang JF,Shi SS,Shao YF,Zhang HZ

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Hypoxia-inducible factor-1alpha (HIF-1alpha) is a transcriptional factor that could improve the stimulation of angiogenesis and the metabolic adaptation of tumor cells to hypoxia. A recent study showed that HIF-1alpha could induce colon cancer cells epithelial-mesenchymal transition (EMT). However, no eviden...

journal_title：Chinese medical journal

authors： Luo Y,He DL,Ning L,Shen SL,Li L,Li X

更新日期：2006-05-05 00:00:00

abstract：BACKGROUND:Personalized medicine becomes essential in lung cancer treatment, however lung-cancer-related gene expression profiles in Chinese patients remain unknown. In this study, the correlation of gene expression profiles and clinical characteristics in non-small-cell lung cancer (NSCLC) was investigated. METHODS:S...

journal_title：Chinese medical journal

authors： Yu D,Li J,Han Y,Liu S,Xiao N,Li Y,Sun X,Liu Z

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Despite the presigmoid transpetrosal approach has been used by different researchers in various ways, the surgical injury rate remains high. Applying a minimally invasive keyhole idea, we devised a presigmoid transpetrosal keyhole approach (PTKA), classified and quantitatively assessed their approach to the ...

journal_title：Chinese medical journal

authors： Wu CY,Lan Q

更新日期：2008-04-20 00:00:00

abstract：BACKGROUND:Peroxisome proliferator-activated receptor (PPAR) alpha is one of the subtypes of PPARs. It regulates metabolism of lipid and lipoprotein, as well as glucose homeostasis. In addition, PPARalpha influences cellular proliferation, inflammation, differentiation and apoptosis, which plays a vital role in cardiov...

journal_title：Chinese medical journal

authors： Yuan J,Wu J,Hang ZG,Zhong XK,Zhou LW,Yu B

更新日期：2008-08-20 00:00:00

abstract：BACKGROUND:Abdominal pain is a common symptom among patients with acute appendicitis, yet these patients have long been denied relief from suffering because of widespread misconceptions associated with the use of opioids. We determined whether morphine hydrochloride masked the physical signs in adults with acute append...

journal_title：Chinese medical journal

authors： Yuan Y,Chen JY,Guo H,Zhang Y,Liang DM,Zhou D,Zhao H,Lin F

更新日期：2010-01-20 00:00:00

abstract：BACKGROUND:C-arm-based flat-panel detector cone-beam computed tomography (CBCT) venography has never been used in the management of iliac vein compression syndrome (IVCS). This study aimed to determine the technical feasibility and safety of CBCT venography in the diagnosis of IVCS compared with conventional venography...

journal_title：Chinese medical journal

authors： Wang CM,Zhang WL,Li X

更新日期：2020-08-26 00:00:00

abstract：BACKGROUND:Green tea has been shown to improve cholesterol metabolism in animal studies, but the molecular mechanisms underlying this function have not been fully understood. Long non-coding RNAs (lncRNAs) have recently emerged as a major class of regulatory molecules involved in a broad range of biological processes a...

journal_title：Chinese medical journal

authors： Liu G,Zheng X,Xu Y,Lu J,Chen J,Huang X

更新日期：2015-01-05 00:00:00

abstract：BACKGROUND:A practical problem impeding clinical translation is the limited bone formation seen in artificial bone grafts. Low-pressure/vacuum seeding and dynamic culturing in bioreactors have led to a greater penetration into the scaffolds, enhanced production of bone marrow cells, and improved tissue-engineered bone ...

journal_title：Chinese medical journal

authors： Wang J,Wang J,Yoshinori A,Paul F,Shen H,Chen J,Sotome S,Liu Z,Shinomiya K

更新日期：2014-01-01 00:00:00

abstract：:131 cases of epidemic hepatitis from two villages in Xinjiang, were admitted to the provisional infectious diseases hospital from February to April 1987. In 125 (95%) patients neither anti-HAV IgM nor anti-HBc IgM were positive. 118 (90%) were drinking water from a local stream of the Hotan River. The study was conduc...

journal_title：Chinese medical journal

authors： Wang XC,Liu XM,Tan CZ,Liu R,Luo SL,Yue XH,Qin F,Bu ZR,Tian X,Song DY

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND:Whether an addition of OAC to double antiplatelet therapy for patients with an indication of chronic oral anticoagulation undergoing PCI-S may improve clinical outcomes is still debated. This meta-analysis aimed to update and re-compare the benefits and risks of triple antithrombotic therapy (TT) with double...

journal_title：Chinese medical journal

authors： Saheb KJ,Deng BQ,Hu QS,Xie SL,Geng DF,Nie RQ

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Airway mucus hypersecretion is an important pathophysiological feature of chronic obstructive pulmonary disease, which is closely associated with cigarette smoking. However, the signal transduction pathway from the cell surface to the nucleus through which cigarette smoke causes upregulation of mucin gene ex...

journal_title：Chinese medical journal

authors： Xiao J,Wang K,Feng YL,Chen XR,Xu D,Zhang MK

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Congenital uterine anomalies are associated with the highest incidence of reproductive failure and obstetric complications. This study aimed to summarize the clinical characteristics and prenatal outcome of pregnancy in women with congenital uterine malformations. METHODS:This retrospective study evaluated ...

journal_title：Chinese medical journal

authors： Zhang Y,Zhao YY,Qiao J

更新日期：2010-02-20 00:00:00

abstract：:To develop a more comprehensive index for predicting the prognous of liver cirrhosis. 300 consecutive patients with cirrhosis were studied in terms of survival from 1975 to 1986. Median follow-up period was 5.3 years. A multivariable survival analysis (Cox's regression model) using clinical biochemical data obtained a...

journal_title：Chinese medical journal

authors： Wang JY,Liu HY,Zhu WN,Han JQ,Dong CY,Shi YJ,Cai HJ,Cao JM,Yi QL

更新日期：1989-04-01 00:00:00

abstract：OBJECTIVE:To investigate the role of a potential diabetes-related mitochondrial region, which includes two previously reported mutations, 3243A-->G and 3316G-->A, in Chinese patients with adult-onset type 2 diabetes. METHODS:A total of 277 patients and 241 normal subjects were recruited for the study. Mitochondrial nt...

journal_title：Chinese medical journal

authors： Yang T,Lam CW,Tsang MW,Tong SF,Kam GY,Chan LY,Poon PM,Wu X,Pang CP

更新日期：2002-05-01 00:00:00