Association and contribution of ERK to IL-6-induced activation of signal transducer and activator of transcription in a human myeloma cell line.

abstract：OBJECTIVE:To explore the effects of thyroid hormone (TH) on cardiac function and peripheral lymphocyte beta-adrenoceptors (beta-ARs) of patients with chronic congestive heart failure (CHF). METHODS:Twenty-eight patients with class III or IV advanced CHF due to dilated cardiomyopathy (DCM) or ischemic cardiomyopathy (I...

journal_title：Chinese medical journal

authors： Lu X,Huang J,Zhang X,Li X,Wang C,Zhang P,Chen Y

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:In China the ginseng root began to be used in medicine over 2000 years ago. Ginsenosides are the most important component isolated from ginseng. The authors investigated the effect of ginsenoside Rg1 on the spectrum of gene expression in the endothelial cells stimulated by TNF-alpha and further explored the ...

journal_title：Chinese medical journal

authors： Lü JP,Ma ZC,Yang J,Huang J,Wang SR,Wang SQ

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:Artificial joints present certain problems such as osteal absorption and lysis induced by wear debris which leads to loosening of the prosthesis over a period of time. Here we propose a design of an artificial magnetic suspension joint that was prepared by integrating the medical theories of modern material ...

journal_title：Chinese medical journal

authors： Dai M,Nie T

更新日期：2010-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy and the mechanism of application of selective head cooling on neuronal morphological damage during postischemic reperfusion in a rabbit model. METHODS:168 New Zealand rabbits were randomized into three groups. Group I [n = 24, (38 +/- 0.5) degrees C, non-ischemic control]; Group II [...

journal_title：Chinese medical journal

authors： Duan M,Li D,Xu J

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:It has been widely demonstrated that endothelial progenitor cells are involved in several diseases and that they have therapeutic implications. In order to define the altered pulmonary vascular homeostasis in chronic obstructive pulmonary disease, we sought to observe the level and functions of circulating e...

journal_title：Chinese medical journal

authors： Yang Y,Gan Y,Cao J,Chen Y,He ZH,Luo H,Cai S,Xiang XD,Zhou R,Chen P

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:The risk of clinical deterioration still exists in the acute phase despite the fact that patients with minor stroke may display less severe symptoms. The impact of this clinical deterioration on long-term outcomes is unknown. We characterized the clinical features of neurological deterioration (ND) in the ac...

journal_title：Chinese medical journal

authors： Ju Y,Zhao XQ,Wang CX,Wang YL,Liu GF,Wang YJ

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Image-guided radiation therapy (IGRT) is the preferred method for curative treatment of localized prostate cancer, which could improve disease outcome and reduce normal tissue toxicity reaction. IGRT using cone-beam computed tomography (CBCT) in combination with volumetric-modulated arc therapy (VMAT) potent...

journal_title：Chinese medical journal

authors： Li M,Li GF,Hou XY,Gao H,Xu YG,Zhao T

更新日期：2016-06-20 00:00:00

abstract：Background:Base excision repair (BER) plays an important role in the maintenance of genome integrity and anticancer drug resistance. This study aimed to explore the role of BER gene polymorphisms in response to chemotherapy for advanced non-small cell lung cancer (NSCLC) patients treated with platinum-based chemotherap...

journal_title：Chinese medical journal

authors： Dong J,Wang X,Yu Y,Yan X,Cui JW

更新日期：2018-08-20 00:00:00

abstract：BACKGROUND:In many studies, obstructive sleep apnea (OSA) has been shown to be an independent risk factor for cardiovascular disease. Conversely, there are few reports establishing possible relation between OSA and venous thromboembolism (VTE). In this study, the aim is to evaluate OSA via polysomnography in patients w...

journal_title：Chinese medical journal

authors： Kezban OS,Ali NA,Umran T,Talha D,Ege GB,Peri A,Leyla YA,Hasan S

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:A number of methods have been used in the treatment of symptomatic and aggressive vertebral hemangioma, but none of them is optimal. Vertebral hemangioma treated with cement vertebroplasty or ethanol injection alone showed relatively good results despite their limitations. METHODS:Between February 2002 and ...

journal_title：Chinese medical journal

authors： Chen L,Zhang CL,Tang TS

更新日期：2007-07-05 00:00:00

abstract：:[This corrects the article DOI: 10.4103/0366-6999.181956.]. ...

journal_title：Chinese medical journal

authors：

更新日期：2016-07-20 00:00:00

abstract：BACKGROUND:Combination paclitaxel and carboplatin is currently a first-line regimen for ovarian cancer. However, many patients develop tumor recurrence or drug resistance to this regimen. The study aims to investigate the effectiveness and safety of an oxaliplatin + epirubicin + ifosfamide regimen for the treatment of ...

journal_title：Chinese medical journal

authors： Zhang G,Li XP,Liu BJ,Wang JL,Wang SJ,Cui H,Wei LH

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:According to the characteristics of digital medicine and the demands of digitalized management in hospitals, we established a storage system that is affordable, highly expandable, and reliable. METHODS:The multi personal computer storage system (MPCSS) was constructed using hardware and software. The image d...

journal_title：Chinese medical journal

authors： Guo Q,Hao F,Duan X,Xie X,Liao W

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:Gingerol is the generic term for pungent constituents in ginger, which has been reported to be effective for inhibiting vomiting. We attempted to investigate the antiemetic effect of gingerol and its effective mechanism on substance P and NK(1) receptors in minks. METHODS:The antiemetic effect of gingerol w...

journal_title：Chinese medical journal

authors： Qian QH,Yue W,Chen WH,Yang ZH,Liu ZT,Wang YX

更新日期：2010-02-20 00:00:00

abstract：BACKGROUND:Advanced glycation end products (AGEs) play a critical role in the development of diabetic nephropathy. Reactive oxygen species (ROS) may play a critical role in AGEs induced growth factor expression. In this study, the effects of AGEs on transforming growth factor beta1 (TGF-beta1), connective tissue growth...

journal_title：Chinese medical journal

authors： Yan HD,Li XZ,Xie JM,Li M

更新日期：2007-05-05 00:00:00

abstract：BACKGROUND:Overexpression of breast cancer-specific gene 1 (SNCG) is associated with poor prognosis in advanced breast cancer patients. This study aimed to determine the effects of SNCG knockdown in breast cancer cells by using small hairpin RNA (shRNA). METHODS:Four different SNCG shRNA oligonucleotides were designed...

journal_title：Chinese medical journal

authors： Shen PH,Fan QX,Li YW,Zhang W,He XK,Wang Z,Zhang YH

更新日期：2011-05-01 00:00:00

abstract：:Ten Chinese Leishmania isolates from different endemic areas and hosts are characterized by isoenzyme electrophoresis for 9 enzymes. Seven were isolated from visceral leishmaniasis patients, one from an infected dog, one from a sandfly and one from a naturally infected racoon dog. Eight of the 10 isolates were indisti...

journal_title：Chinese medical journal

authors： Xu ZB,Liu ZT,Long JY,Chai JJ,Chen WK

更新日期：1989-09-01 00:00:00

abstract：BACKGROUND:Lumbar spinal stenosis is a common problem that is receiving attention with the advent of novel treatment procedures. Prior positional MRI studies demonstrated lumbar canal diameter changes with flexion and extension. There have not been any studies to examine the amount of spinal canal diameter change relat...

journal_title：Chinese medical journal

authors： Wei F,Wang J,Zou J,Hong SW,Zhang H,He W,Miyazaki M,Lee SH,Alanay A

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:This retrospective study aimed to investigate the difference of the intra-dural reserving space for spinal cord in magnetic resonance imaging (MRI) between patients with and without developmental cervical stenosis and its clinical significance. METHODS:A total of 264 patients with cervical spondylotic myelo...

journal_title：Chinese medical journal

authors： Tang Y,Yu M,Liu Z,Sun Y,Liu X

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Severe valgus deformity often has bone defect and laxity of the medial ligamentous, and total knee arthroplasty in severe valgus knee is, in most cases, more challenging for surgeons. The usefulness of a computer assisted navigation system in reestablishing the mechanical axis has been well established. Henc...

journal_title：Chinese medical journal

authors： Shao JJ,Zhang XL,Wang Q,Chen YS,Shen H,Jiang Y

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Alzheimer disease (AD) is a neurodegenerative disease related to aging. At present, its pathological mechanisms remain unclear. Family members of the renin-angiotensin system (RAS) play a role in neuronal plasticity, as well as formation of learning and memory. In this study, we explore the effects of altere...

journal_title：Chinese medical journal

authors： Hou DR,Wang Y,Zhou L,Chen K,Tian Y,Song Z,Bao J,Yang QD

更新日期：2008-11-20 00:00:00

abstract：BACKGROUND:Water-electrolyte disturbance and endocrine alterations are common complications of adult patients with craniopharygioma in the postoperative period and may affect their recovery and prognosis. Some of these complications even lead to death. Appropriate remedy based upon the status of water-electrolyte balan...

journal_title：Chinese medical journal

authors： Wang L,Zhao SF,Zhang W,Zhang MZ

更新日期：2006-08-20 00:00:00

abstract：:The RV lead position, either RVA or RVHS appears to make no difference in the response to CRT but the LV lead placement play a vital role.9,30 The latest activated regions of LV or areas without transmural myocardial scar for an optimal CRT are preferred. Currently, data demonstrate that no significant difference of c...

journal_title：Chinese medical journal

authors： Dong YX,Boodhna J,Yang YZ

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Psoriasis is a chronic inflammatory skin disease, affecting about 0.6% of the Chinese population. Many patients are not well controlled by conventional treatments, thus there is need for new treatment regimens. In this study, we assessed the efficacy and safety of secukinumab in Chinese patients with moderat...

journal_title：Chinese medical journal

authors： Cai L,Zhang JZ,Yao X,Gu J,Liu QZ,Zheng M,Zhang SF,Xu JH,Li CX,Cheng H,Guo Q,Pan WL,Li SQ,Li RY,Guo ZP,Song ZQ,Li SS,Dong XQ,Wang L,Fu R,Regnault P,Charef P,Mazur R,Patekar M

更新日期：2020-11-20 00:00:00

abstract：BACKGROUND:Total hip arthroplasty (THA) in developmental dysplasia of the hip (DDH) is more complex than the normal hip, with large replacement risks and many complications. Although nonosteotomy THA is convenient to perform, femoral osteotomy shortening can avoid blood vessel and nerve traction injuries. This study ai...

journal_title：Chinese medical journal

authors： Chu YM,Zhou YX,Han N,Yang DJ

更新日期：2016-02-05 00:00:00

abstract：BACKGROUND:Irritable bowel syndrome (IBS) is reported associated with the alteration of gut microbial composition termed as dysbiosis. However, the pathogenic mechanism of IBS remains unclear, while the studies of Chinese individuals are scarce. This study aimed to understand the concept of dysbiosis among patients wit...

journal_title：Chinese medical journal

authors： Wang Z,Xu CM,Liu YX,Wang XQ,Zhang L,Li M,Zhu SW,Xie ZJ,Wang PH,Duan LP,Zhu HQ

更新日期：2019-04-20 00:00:00

abstract：BACKGROUND:Renal artery stenosis (RAS) is always associated with abnormalities in renal microvascular perfusion (RMP). However, few imaging methods can simultaneously evaluate the degree of luminal stenosis and RMP. Thus, this study will aim to evaluate the feasibility of using contrast-enhanced ultrasound (CEUS) for a...

journal_title：Chinese medical journal

authors： Ren JH,Ma N,Wang SY,Sun YJ,Zhang YW,Guo FJ,Li YJ,Li TH,Ai H,Zhang WD,Li P,Ma WH

更新日期：2019-01-05 00:00:00

abstract：BACKGROUND:Monolayer cell culture models are the traditional culture models used for in vitro research of pancreatic carcinoma chemosensitivity. However, these models neglect the interactions between tumor cells and the impact of the tumor microenvironment. Such tumor cell monolayers poorly mimic the solid tumor microe...

journal_title：Chinese medical journal

authors： Liao Q,Hu Y,Zhao YP,Zhou T,Zhang Q

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Gastric varices (GV) are life-threatening for patients with portal hypertension. Endoscopic injection with butyl cyanoacrylate (BC), the mainstay of the therapy for GV, has been reported to be effective for hemostasis of bleeding varices, but its efficacy in the obliteration of GV and impact on the survival ...

journal_title：Chinese medical journal

authors： Cheng LF,Wang ZQ,Li CZ,Cai FC,Huang QY,Linghu EQ,Li W,Chai GJ,Sun GH,Mao YP,Wang YM,Li J,Gao P,Fan TY

更新日期：2007-12-05 00:00:00

abstract：:Myocardial revascularization by Nd: YAG laser used in rats with myocardial infarction was studied. The left coronary artery was ligated and the laser channels with a diameter of 300 microns were made immediately by 2.5-4.2 W lasersonics YAG unit. After 24 hours, the rats were killed. Evaluation included hemodynamics, ...

journal_title：Chinese medical journal

authors： Guo JX,Pan J,Ma L,Chen MZ,Xu H,Shi AY

更新日期：1993-09-01 00:00:00