Association of Base Excision Repair Gene Polymorphisms with the Response to Chemotherapy in Advanced Non-Small Cell Lung Cancer.

abstract：BACKGROUND:The acetabular teardrop is often used to guide acetabular component placement in total hip arthroplasty (THA). Placing the lower acetabular component aspect at the same level as the lower teardrop edge was assumed to restore the hip center of rotation. Here we radiographically analyzed the relationship betwe...

journal_title：Chinese medical journal

authors： Lu Y,Cheng L,Guo W,Yu Q,Gao F,Zhang Q,Liu Z,Sun W,Shi Z

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Adenomyosis is a gynecological disorder with symptoms most presenting as dysmenorrhea and heavy menstrual bleeding. However, the presence of lower urinary tract symptoms (LUTS) among women with adenomyosis remains unclear. This study was designed to determine the prevalence of LUTS and factors related to the...

journal_title：Chinese medical journal

authors： Li T,Xu XX,Dai Y,Zhang JJ,Lang JH,Leng JH

更新日期：2017-07-05 00:00:00

abstract：BACKGROUND:The activation of extracellular signal-regulated kinase1/2 (ERK1/2) has been shown to be important signaling pathway in the ischemic preconditioning (IPC) response. Recently, some studies suggest a key role for the mitochondrial ATP-sensitive potassium channel (mKATP) as both a trigger and an end effector of...

journal_title：Chinese medical journal

authors： Gong KZ,Zhang ZG,Li AH,Huang YF,Bu P,Dong F,Liu J

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:Gastric cancer (GC) is one of the most globally prevalent cancers in the world. The pathogenesis of GC has not been fully elucidated, and there still lacks effective targeted therapeutics. The influence of altered kinesin superfamily protein 22 (KIF22) expression in GC progression is still unclearly. The aim...

journal_title：Chinese medical journal

authors： Yu ZY,Jiang XY,Zhao RR,Qin JJ,Luo CJ,Ren YX,Ren W,Ma ZJ,Jiao ZY

更新日期：2020-04-20 00:00:00

abstract：BACKGROUND:Some individuals have multiple renal arteries. Severe stenosis in one of the arteries may cause refractory hypertension. The detection of stenosis within one of the multiple renal arteries usually required invasive procedures, such as computed tomographic angiography (CTA) and magnetic resonance angiography ...

journal_title：Chinese medical journal

authors： Qin W,Zhang X,Yang M,Zhong XH,Zhao MH

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVE:This review focuses on the role of the large conductance calcium-activated potassium (BKCa) channels in diabetic vascular complications. DATA SOURCES:Relevant articles published in English or Chinese from 1981 to present were selected from PubMed. The search terms were "BKCa channels" and "diabetes". Importa...

journal_title：Chinese medical journal

authors： Qian L,Liu X,Wang R

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVES:To assess the feasibility and efficacy of eliciting leukemia-specific T-cell responses in syngeneic mice in vitro and in vivo using dendritic cells (DCs) pulsed with total RNA from leukemia cells. METHODS:DCs generated from bone marrow culture in vitro in the presence of combined cytokines were pulsed with ...

journal_title：Chinese medical journal

authors： Li M,You S,Ge W,Ma S,Ma N,Zhao C

更新日期：2003-11-01 00:00:00

abstract：OBJECTIVE:To determine whether mutation of the coding or junction region of glucokinase gene (GCK) is also the pathogenic cause of the common form of non-insulin-dependent diabetes mellitus (NIDDM) in Chinese. METHODS:Single strand conformation polymorphism (SSCP) analysis was performed after the 12 exons and junction...

journal_title：Chinese medical journal

authors： Xiang K,Wu S,Zheng T,Sun D,Wang Y,Pu L

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND:Long-term use of benzalkonium chloride (BAC)-preserved drugs is often associated with ocular surface toxicity. Ocular surface symptoms had a substantial impact on the glaucoma patients' quality of life and compliance. This study aimed to investigate the effects of sodium hyaluronate (SH) on ocular surface to...

journal_title：Chinese medical journal

authors： Liu X,Yu FF,Zhong YM,Guo XX,Mao Z

更新日期：2015-09-20 00:00:00

abstract：BACKGROUND:Laparoendoscopic single-site surgery radical prostatectomy (LESS-RP) is a challenging urological procedure and needs to be further evaluated. This study was undertaken to illustrate the safety and initial results of pure LESS-RP with conventional available instruments. METHODS:A prospective clinical databas...

journal_title：Chinese medical journal

authors： Zhu G,Zhang YQ,Grange P,Walsh K,Jin B,Zhang YG,Chen X,Wang X,Wei D,Wan B,Wang JY

更新日期：2012-11-01 00:00:00

abstract：:T cell subsets in peripheral blood were phenotyped in 56 patients with different stages of Schistosomiasis japonica, including 17 with acute, 14 with chronic and 25 with advanced infection. The activity of interleukin-1 (IL-1) produced by peripheral blood mononuclear cells (PBMC) induced by lipopolysaccharide (LPS) in...

journal_title：Chinese medical journal

authors： Li ZJ,Yang Q,Yang YX,Zeng LL,Li SL,Dai JZ,Wang HC,Luo DD,Wang XH

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND:After total hip arthroplasty (THA), there is a noteworthy inflammatory response. The inflammatory response is associated with postoperative recovery and complications. However, there had been few reports on the relationship between inflammatory response and postoperative complication rate. The aim of the pre...

journal_title：Chinese medical journal

authors： Chen XX,Wang T,Li J,Kang H

更新日期：2016-11-05 00:00:00

abstract：BACKGROUND:Although the early clinical outcomes of total knee arthroplasty (TKA) using minimally invasive surgery techniques have been widely described, data on the mid- to long-term outcomes are limited. We designed a retrospective study to compare the two most common TKA techniques - The modified quadriceps-sparing (...

journal_title：Chinese medical journal

authors： Huang AB,Wang HJ,Yu JK,Yang B,Ma D,Zhang JY

更新日期：2015-07-20 00:00:00

abstract：:Aluminium citrate (Al-cit) was shown to be biologically effective in preventing silicosis. A total of 917 cases selected from both engineering corps of railway and coalmines with stage 0 or 0+ by radiographs were studied. Cases were randomly divided into Al-cit treatment group and control group with continuing dust ex...

journal_title：Chinese medical journal

authors： Zou SQ,Liu H,Zhou YY,Su KQ,Qi KY,Guan SM,Liu SJ

更新日期：1990-02-01 00:00:00

abstract：BACKGROUND:MicroRNAs (miRNAs) are small noncoding regulatory RNAs whose aberrant expression may be observed in many malignancies. However, few data are yet available on human primary medulloblastomas. This work aimed to identify that whether miRNAs would be aberrantly expressed in tumor tissues compared with non-tumoro...

journal_title：Chinese medical journal

authors： Liu W,Gong YH,Chao TF,Peng XZ,Yuan JG,Ma ZY,Jia G,Zhao JZ

更新日期：2009-10-20 00:00:00

abstract：OBJECTIVE:To analyse the relationship between age and treatment with captopril after acute myocardial infarction (AMI). METHODS:In a randomized trial, 822 patients with a first AMI received conventional medical treatment, including intravenous thrombolytic therapy and oral aspirin or metoprolol, and then were randomly...

journal_title：Chinese medical journal

authors： Cai X,Shen W,Gong L

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:Bioactive proteins, such as cytokines and chemokines, have not been systematically evaluated in healthy and preeclamptic pregnancies. We aimed to investigate the difference of these proteins between healthy and preeclamptic pregnancies in order to help clarify their potential roles in the pathogenesis of hyp...

journal_title：Chinese medical journal

authors： Wang T,Wang YY,Zhou R,Song CP,Lin W,Niu XY,Zhang L,Hu HZ

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Pulsed radiofrequency (PRF) application to the dorsal root ganglia can reduce neuropathic pain (NP) in animal models, but the effect of PRF on damaged peripheral nerves has not been examined. We investigated the effect of PRF to the rat sciatic nerve (SN) on pain-related behavior and SN ultrastructure follow...

journal_title：Chinese medical journal

authors： Li DY,Meng L,Ji N,Luo F

更新日期：2015-02-20 00:00:00

abstract：BACKGROUND:The interaction between activated microglia and T lymphocytes can yield abundant pro-inflammatory cytokines. Our previous study proved that thymus immune tolerance could alleviate the inflammatory response. This study aimed to investigate whether intrathymic injection of myelin basic protein (MBP) in mice co...

journal_title：Chinese medical journal

authors： Cui ZQ,Liu BL,Wu QL,Cai Y,Fan WJ,Zhang MC,Ding WL,Zhang B,Kang JM,Yan H

更新日期：2016-04-05 00:00:00

abstract：BACKGROUND:As a new electroencephalogram (EEG) signal processing technique for monitoring the depth of anesthesia, entropy consists of two indices: reaction entropy (RE) and state entropy (SE). Our study compared entropy with classical bispectral index (BIS) in reduction of myoelectrical interference and noxious stimul...

journal_title：Chinese medical journal

authors： Gao JD,Zhao YJ,Xu CS,Zhao J,Huang YG,Wang TL,Pei L,Wang J,Yao LN,Ding Q,Tan ZM,Zhu ZR,Yue Y

更新日期：2012-04-01 00:00:00

abstract：:An epidemiological study on the incidence and prevalence of Parkinson's disease (PD) was carried out in 29 provinces, cities and autonomous regions in this country in 1986. The survey was conducted in 117 areas, and 566 patients with PD were found among 3,869,162 persons examined, giving a point prevalence for men and...

journal_title：Chinese medical journal

authors： Wang YS,Shi YM,Wu ZY,He YX,Zhang BZ

更新日期：1991-11-01 00:00:00

abstract：BACKGROUND:Volatile anesthetics (VAs) may affect varied and complex physiology processes by manipulating Ca(2+)-calmodulin (CaM). However, the detailed mechanism about the action of VAs on CaM has not been elucidated. This study was undertaken to examine the effects of VAs on the conformational change, hydrophobic site...

journal_title：Chinese medical journal

authors： Zhou MM,Xia HM,Liu J,Xu YN,Xin NX,Zhang SH

更新日期：2012-09-01 00:00:00

abstract：:Somatosensory evoked potentials (SEP) arising from median nerve stimulation were recorded in 102 patients with unilateral cerebral hemorrhage or infarct located in basal ganglion, internal capsule, thalamus or cerebral lobe. Of them 42 cases were followed up and reexamined with SEPs. Three types of SEPs were observed:...

journal_title：Chinese medical journal

authors： Lu ZN,Yu SZ

更新日期：1993-01-01 00:00:00

abstract：Background:Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening clinical syndrome. Central nervous system (CNS) involvement is a severe complication, which can lead to rapid disease development and higher morality. However, this has not been given enough attention in adult HLH. Therefore, we carried out this ...

journal_title：Chinese medical journal

authors： Song Y,Pei RJ,Wang YN,Zhang J,Wang Z

更新日期：2018-04-05 00:00:00

abstract：BACKGROUND:Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is considered to have high value in the staging of mediastinal lymph nodes in lung cancer. The current study was conducted to investigate the diagnostic value of EBUS-TBNA in intrapulmonary lesions located near the central airway. ...

journal_title：Chinese medical journal

authors： Zhao H,Xie Z,Zhou ZL,Sui XZ,Wang J

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Extracellular matrix (ECM) orchestrates cell behaviour including growth, death, apoptosis, adhesion, migration, and invasion by activating several signalling pathways. Certain components of ECM, such as integrins, may act as receptors or co-receptors of enterovirus. ECM-activated gene expressions in myocardi...

journal_title：Chinese medical journal

authors： Zhang ZC,Li SJ,Yang YZ,Chen RZ,Ge JB,Chen HZ

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Periostin originally designated osteoblast-specific factor 2 (OSF-2) is frequently found to be highly expressed in various types of human cancer cell lines in vitro and human cancer tissues in vivo. We proposed that periostin was a key factor during the process of proliferation and invasion in cancer cells. ...

journal_title：Chinese medical journal

authors： Liu C,Huang SJ,Qin ZL

更新日期：2010-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the safety and immunogenicity of lyophilized, live attenuated hepatitis A vaccine (H2 strain) in rhesus monkeys. METHODS:Nine adult rhesus monkeys were used as experimental animals. The rhesus monkeys without anti-HAV were divided randomly into the aqueous vaccination group (4 rhesus monkeys), th...

journal_title：Chinese medical journal

authors： Hu Y,Tan S,Shao C,Jin W,Ji Q,He J,Chen H,Yan J

更新日期：2000-04-01 00:00:00

abstract：BACKGROUND:Preoperative incisional local anaesthesia with ropivacaine is a common method of providing post-laparoscopy pain relief. The pulmonary recruitment manoeuvre also provides pain relief, but the combined effect of these two methods on pain following laparoscopic procedures has not been reported. We investigated...

journal_title：Chinese medical journal

authors： Liu H,Ma C,Zhang X,Yu C,Yang Y,Song X,Tang Y,Guo X

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Recent studies suggest that circulating DNA may be a potential tumor marker for lung cancer, but most of these studies are conducted between healthy controls and lung cancer patients, with few or no benign lung disease patients included. The objective of this study was to evaluate the performance of plasma D...

journal_title：Chinese medical journal

authors： Xie GS,Hou AR,Li LY,Gao YN,Cheng SJ

更新日期：2004-10-01 00:00:00