Abstract：
BACKGROUND:Severe valgus deformity often has bone defect and laxity of the medial ligamentous, and total knee arthroplasty in severe valgus knee is, in most cases, more challenging for surgeons. The usefulness of a computer assisted navigation system in reestablishing the mechanical axis has been well established. Hence, the interest for surgeons is how the navigation system makes the procedure of total knee arthroplasty with severe valgus knee easier. METHODS:From June 2006 to March 2008 in Department of Joint Surgery, Shanghai Sixth People's Hospital, 6 patients (7 knees) with severe valgus knee underwent total knee arthroplasty using the Stryker Navigation system, which is an active wireless and imageless system. All the patients were followed up for 12 to 18 months after surgery. The X-ray radiographs for whole limbs were obtained on all patients to determine preoperative and postoperative alignments. RESULTS:A primary, posterior stabilized prosthesis was utilized in all cases. The average preoperative overall mechanical axis of the seven knees was 19.6° ± 4.6° of valgus (range 16° to 29°), and the average postoperative mechanical axis was 0.4° ± 0.7° (range 0.8° varus to 1.4° valgus). CONCLUSIONS:The navigation system is a very effective and useful tool for accurate intraoperative restoration of alignment in the face of significant deformity with valgus knee. To prevent component malposition, we did not reduce the knee before solidification of bone cement but controlled alignment using the navigation system up to implantation of the final component.
journal_name
Chin Med J (Engl)journal_title
Chinese medical journalauthors
Shao JJ,Zhang XL,Wang Q,Chen YS,Shen H,Jiang Ysubject
Has Abstractpub_date
2010-10-01 00:00:00pages
2666-70issue
19eissn
0366-6999issn
2542-5641journal_volume
123pub_type
杂志文章abstract：BACKGROUND:There are few reports of microsurgical treatment of dorsum sellae meningiomas-which, because of location, size, and differences in growth direction, clinical presentations, degree of surgical difficulty, have varied posttreatment sequelae. In pursuit of an optimal microsurgical treatment option for dorsum se...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
更新日期：2009-08-20 00:00:00
abstract：BACKGROUND:Sinus of Valsalva aneurysm (SVA) is a rare anomaly and few large or long-term series are well established. This study was designed to review 33-year surgical experience of SVA in one center. METHODS:From August 1980 to December 2013, patients with SVA underwent surgical repair were retrospectively studied. ...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
更新日期：2014-01-01 00:00:00
abstract：OBJECTIVE:To detect the virus in the feces and sera of patients in an outbreak of enterically transmitted non-A, non-E hepatitis, and this review covers the epidemiologic features and experimental infection of this novel virus. DATA SOURCES:Data sources come from our own work on this subject, published and unpublished...
journal_title：Chinese medical journal
pub_type： 杂志文章,评审
doi：
更新日期：2001-11-01 00:00:00
abstract：OBJECTIVE:Polymorphism in vitamin D receptor (VDR) gene has been reported to play a major role in variations for genetic regulation of bone mass. Its role within various ethnic populations is not clear. The purpose of this study was to determine the frequencies of VDR genotypes in the Han and Uygur nationalities in Chi...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
更新日期：2000-09-01 00:00:00
abstract：OBJECTIVE:To investigate the effects of the combination of octreotide and aspirin on the growth of gastric cancer. METHODS:Proliferation of gastric cancer cell lines treated with octreotide or aspirin was determined by (3)H-thymidine incorporation. After xenografts of human gastric cancer were implanted orthotopically...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
更新日期：2003-03-01 00:00:00
abstract：OBJECTIVE:Parkinson's disease (PD) is featured with motor disorder and nonmotor manifestations including psychological symptoms, autonomic nervous system dysfunction, and paresthesia, which results in great inconvenience to the patients' life. The apolipoprotein (Apo) superfamily, as a group of potentially modifiable b...
journal_title：Chinese medical journal
pub_type： 杂志文章,评审
doi：10.4103/0366-6999.217092
更新日期：2017-11-05 00:00:00
abstract：Background:Facioscapulohumeral muscular dystrophy (FSHD) is characterized by asymmetric muscular deficit of facial, shoulder-girdle muscles, and descending to lower limb muscles, but it exists in several extramuscular manifestations or overlapping syndromes. Herein, we report a "complex disease plus" patient with FSHD1...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：10.4103/0366-6999.240797
更新日期：2018-09-20 00:00:00
abstract：ABSTRACT:Cerebral small vessel disease (SVD) is a common global brain disease that causes cognitive impairment, ischemic or hemorrhagic stroke, problems with mobility, and neuropsychiatric symptoms. The brain damage, seen as focal white and deep grey matter lesions on brain magnetic resonance imaging (MRI) or computed ...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：10.1097/CM9.0000000000001177
更新日期：2020-10-06 00:00:00
abstract：:Osteoarthritis (OA) models in bipedal rats were used to study the immune response, including the changes of IgG, antibody dependent cytotoxicity tests toward articular chondrocytes and the matrix. The results revealed significant difference between the bipedal and the quadruped rats. Immunological studies have proved ...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
更新日期：1991-03-01 00:00:00
abstract：OBJECTIVE:To investigate the effect of L-arginine (L-arg) on early compensatory renal growth (CRG), tubulointerstitial accumulation of extracellular matrix (ECM), long term survival rate and renal scarring in rats with 5/6 nephrectomy (SNx). METHODS:The experiment included four groups of rats (n = 5 each group): (1) S...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
更新日期：2002-02-01 00:00:00
abstract：OBJECTIVE:To improve the prognosis and therapeutic efficacy of Waldeyer's ring non-Hodgkin lymphoma (NHL-WR), combined radio-chemotherapy was used to treat the patients with NHL-WR and prognostic factors were analyzed. METHODS:Ninety patients with stage I-IV NHL-WR were treated with combined radio-chemotherapy. 4000 c...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
更新日期：2000-02-01 00:00:00
abstract：OBJECTIVE:To investigate the role of AC-cAMP system in the transmission of the action of the growth hormone releasing hormone (GRH) on growth hormone (GH) release in pituitary GH-secreting adenomas. METHODS:The effects of GRH (10(-7) mol/L) on intracellular cAMP levels and GH release and the effects of AC-cAMP stimula...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
更新日期：1996-08-01 00:00:00
abstract：:Apolipoprotein (a) [Lp(a)] phenotypes of 69 myocardial infarction survivor and 56 stroke patients were reported and compared to those of 190 healthy Chinese. The results revealed that the distributions of apo(a) phenotype frequency in patients with cardio-cerebrovascular disease (CCVD) were different from those of con...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
更新日期：1994-02-01 00:00:00
abstract：BACKGROUND:Mitochondrial DNA 4977-bp deletion (DeltamtDNA(4977)) was reported in many human neoplasia. However, its biological significance remains to be evaluated and the molecular mechanism needs to be investigated. In this study, we analyzed the frequency of DeltamtDNA(4977) in gastric cancer (GC) cell lines and tis...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
更新日期：2009-02-20 00:00:00
abstract：:Dextrocardia is a rare anomaly where the heart is located on the right side of the chest instead of the normal left side. Ablation of atrial fibrillation (AF) with such an inverted anatomy may be challenging for the manipulation of the catheters. Here we report a case of dextrocardia who underwent ablation for persist...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
更新日期：2012-05-01 00:00:00
abstract：BACKGROUND:The effectiveness of neoadjuvant chemoradiotherapy (NCRT) treatment for patients with esophageal carcinoma (EC) remains controversial. The aim of this study was to compare the effect of NCRT followed by surgery (NCRTS) with surgery alone (SA) for EC. METHODS:The PubMed, EMBASE, and the Cochrane Library data...
journal_title：Chinese medical journal
pub_type： 杂志文章,meta分析
doi：10.4103/0366-6999.195464
更新日期：2016-12-20 00:00:00
abstract：BACKGROUND:It has been confirmed that defective expression of human leukocyte antigen class I (HLA-I) molecules can contribute to the immune evasion of cancer cells in some types of cancer. The aim of this study was to examine the expression of HLA class I antigen and the antigen-processing machinery (APM) components i...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
更新日期：2011-02-01 00:00:00
abstract：BACKGROUND:Recent studies have suggested that cancer stem cells cause tumor recurrence based on their resistance to radiotherapy and chemotherapy. Although the highly invasive nature of glioblastoma cells is also implicated in the failure of current therapies, it is not clear whether cancer stem cells are involved in i...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
更新日期：2011-09-01 00:00:00
abstract：OBJECTIVE:To investigate the feasibility of adrenal sparing surgery for selected renal cell carcinoma (RCC), since the necessity of routine adrenalectomy during radical nephrectomy for RCC has been challenged in recent years. METHODS:178 patients underwent perifascial nephrectomy in a 16-year period. Of these patients...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
更新日期：1998-10-01 00:00:00
abstract：OBJECTIVE:To study whether human umbilical cord blood CD34+ cells transduced with human aldehyde dehydrogenase class-1 (ALDH-1) and multidrug resistance gene (MDR1) have increases resistance to 4-Hydroperoxycyclo-phosphamide (4-HC) and P-glycoprotein effluxed drugs. METHODS:A bicistronic retroviral vector G1Na-ALDH1-I...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
更新日期：2001-01-01 00:00:00
abstract：: ...
journal_title：Chinese medical journal
pub_type： 社论
doi：10.4103/0366-6999.245275
更新日期：2018-11-20 00:00:00
abstract：BACKGROUND:The acute abdomen remains a challenge for all obstetricians and physicians who take part in the care of women in pregnancy. To add substantially to our understanding of acute pancreatitis (AP) in pregnancy, in particular affirming the increased risks for mother and fetus associated with AP, we explored featu...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
更新日期：2011-09-01 00:00:00
abstract：BACKGROUND:Over 70% of the total tissue weight in the cartilage matrix consists of water, and the early-stage osteoarthritic cartilage is characterized by swelling. Water transport in the cartilage matrix and across the membranes of chondrocytes may be important in normal and pathological conditions of cartilage. The p...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
更新日期：2007-12-20 00:00:00
abstract：BACKGROUND:Combination therapy is an effective method to reduce the blood pressure (BP) for patients with hypertension. This study was performed to evaluate the efficacy and safety of benazepril/lercanidipine compared with benazepril alone in patients with mild-to-moderate hypertension. METHODS:One hundred and eighty-...
journal_title：Chinese medical journal
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2013-06-01 00:00:00
abstract：OBJECTIVE:To detect occult metastases in lymph nodes from patients with colorectal carcinoma and its clinical significance. METHODS:The metastases in 260 lymph nodes from 39 histologically verified colorectal cancer patients were studied by both hematoxylin-eosin (HE) staining and cytokeratin-20 (CK20) specific RT-PCR...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
更新日期：2002-04-01 00:00:00
abstract：OBJECTIVE:To provide epidemiological data for revising the diagnostic criteria of neonatal hyperbilirubinemia in China. METHODS:A survey was performed among full-term infants in multiple centers throughout the country. From less than 24 hours after birth, the infants' bilirubin levels were measured every day until the...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
更新日期：2001-04-01 00:00:00
abstract：BACKGROUND:Nontraumatic spontaneous subarachnoid hemorrhage (SAH) is associated with a high mortality. This study was conducted to investigate the epidemiological features of nontraumatic spontaneous SAH in China. METHODS:From January 2006 to December 2008, the clinical data of patients with nontraumatic SAH from 32 m...
journal_title：Chinese medical journal
pub_type： 杂志文章,多中心研究
doi：10.4103/0366-6999.202729
更新日期：2017-04-05 00:00:00
abstract：BACKGROUND:Dry eye patients suffer from all kinds of symptoms. Sometimes, the clinical signs evaluation does not disclose any obvious difference in routine examination; in vivo confocal microscopy (IVCM) is a powerful tool for ocular surface disease. This study aimed to clarify meibomian gland (MG) alterations in dry e...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：10.4103/0366-6999.192782
更新日期：2016-11-05 00:00:00
abstract：OBJECTIVE:Renal fibrosis is the most common manifestation of chronic kidney disease (CKD). Noting that existing treatments of renal fibrosis only slow disease progression but do not cure it, there is an urgent need to identify novel therapies. Hydrogen sulfide (H2S) is a newly discovered endogenous small gas signaling ...
journal_title：Chinese medical journal
pub_type： 杂志文章,评审
doi：10.1097/CM9.0000000000000537
更新日期：2019-12-05 00:00:00
abstract：OBJECTIVE:To analyse the relationship between age and treatment with captopril after acute myocardial infarction (AMI). METHODS:In a randomized trial, 822 patients with a first AMI received conventional medical treatment, including intravenous thrombolytic therapy and oral aspirin or metoprolol, and then were randomly...
journal_title：Chinese medical journal
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2001-07-01 00:00:00
