Role of peroxisome proliferator-activated receptor alpha activation in acute myocardial damage induced by isoproterenol in rats.

abstract：Background:Signal transducer and activator of transcription 3 (STAT3) was strongly expressed and activated in psoriatic keratinocytes (KCs) and correlated with the severity of psoriasis. The study aimed to investigate the effects of STAT3 small interfering RNA (siRNA) combined with ultrasonic irradiation and SonoVue mi...

journal_title：Chinese medical journal

authors： Ran LW,Wang H,Lan D,Jia HX,Yu SS

更新日期：2018-09-05 00:00:00

abstract：:The CRIEPI initiated the Radiation Hormesis Research based on the following rationale. If the Luckey's claim was true, our daily activities in the radiation management would be extremely erroneous. If the Luckey's claim was false, the concept publicated would bring us serious disturbance on the radiation management in...

journal_title：Chinese medical journal

authors： Hattori S

更新日期：1994-06-01 00:00:00

abstract：:In 16 dogs the endothelium of the left anterior descending coronary artery was injured mechanically. Then a copper wire was inserted into the lumen as a choke of flow and the vessel was slightly compressed from outside by a constrictor. Eight dogs had been treated beforehand with a preparation of flavone extracted fro...

journal_title：Chinese medical journal

authors： Zhao HY,Fang WY

更新日期：1991-09-01 00:00:00

abstract：BACKGROUND:Ischemic disease is one of the leading causes of death in the world. In order to further study gene therapy for ischemic disease, we constructed a recombinant plasmid for co-expression of human angiopoietin-1 and vascular endothelial growth factor 165(VEGF165) gene in adeno-associated virus (AAV) gene delive...

journal_title：Chinese medical journal

authors： Chen DJ,Tan Z,Xie YL,Liu F

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:Variations in position and relationship between the internal jugular vein (IJV) and the common carotid artery (CCA) may lead to inadvertent artery puncture which could be disastrous during central venous access. We demonstrated the anatomic relationship of the IJV with CCA in order to find the optimal site a...

journal_title：Chinese medical journal

authors： Qin XH,Zhang H,Mi WD

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Collagen VI-related myopathies are autosomal dominant and recessive hereditary myopathies, mainly including Ullrich congenital muscular dystrophy (UCMD) and Bethlem myopathy (BM). Muscle magnetic resonance imaging (MRI) has been widely used to diagnosis muscular disorders. The purpose of this study was to ev...

journal_title：Chinese medical journal

authors： Fu J,Zheng YM,Jin SQ,Yi JF,Liu XJ,Lyn H,Wang ZX,Zhang W,Xiao JX,Yuan Y

更新日期：2016-08-05 00:00:00

abstract：:Free radicals in the gasphase of cigarette smoke were determined by spin trapping agent PBN (N-tert-butyl-2-phenyl nitrone) and DMPO (5,5-dimethyl-1-pyrroline-oxide) on electron spin resonance spectrometer. They were identified according to the spectrum parameters calculated from the spectra. The free radicals mainly ...

journal_title：Chinese medical journal

authors： Zhao BL,Yan LJ,Hou JW,Xin WJ

更新日期：1991-07-01 00:00:00

abstract：BACKGROUND:Up to now there have been no satisfactory drugs to treat psychiatric disorders, and now bioactive compound from entomagenous fungi (BCEF0083) is a new type of bioactive compound from entomopathogenic fungi. Our previous investigations have shown that BCEF has an inhibition effect on monoamine oxidase. So, BC...

journal_title：Chinese medical journal

authors： Zhou LL,Ming L,Ma CG,Cheng Y,Jiang Q

更新日期：2005-06-05 00:00:00

abstract：BACKGROUND:The Ras/Raf/ERK1/2 signaling pathway controls many cellular responses such as cell proliferation, migration, differentiation, and death. In the nervous system, emerging evidence also points to a death-promoting role for ERK1/2 in both in vitro and in vivo models of neuronal death. To further investigate how ...

journal_title：Chinese medical journal

authors： Cao FJ,Zhang X,Liu T,Li XW,Malik M,Feng SQ

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:The molecular mechanisms underlying the endometriosis are still not completely understood. In order to test the hypothesis that the approaches in phosphoproteomics might contribute to the identification of key biomarkers to assess disease pathogenesis and drug targets, we carried out a phosphoproteomics anal...

journal_title：Chinese medical journal

authors： Xu HM,Deng HT,Liu CD,Chen YL,Zhang ZY

更新日期：2015-10-05 00:00:00

abstract：BACKGROUND:Previous studies demonstrated that vagus nerve stimulation (VNS) is an effective therapy for drug-resistant epilepsy. Acupuncture is also used to treat epilepsy. This study was designed to examine the safety and effectiveness of transcutaneous auricular vagus nerve stimulation (ta-VNS) for patients with drug...

journal_title：Chinese medical journal

authors： Rong P,Liu A,Zhang J,Wang Y,Yang A,Li L,Ben H,Li L,Liu R,He W,Liu H,Huang F,Li X,Wu P,Zhu B

更新日期：2014-01-01 00:00:00

abstract：:Five hundred patients with aortoarteritis were studied in this series. The long-term administration of small dosage of corticosteroid is effective in treating this disease in its active stage. The patients with renal vascular hypertension should be treated by percutaneous transluminal renal angioplasty or by surgery i...

journal_title：Chinese medical journal

authors： Zheng DY,Liu LS,Fan DJ

更新日期：1990-07-01 00:00:00

abstract：BACKGROUND:Cervical arthroplasty is indicated to preserve cervical motion and prevent accelerated adjacent segment degeneration. Whether accelerated adjacent segment degeneration is prevented in the long term is unclear. This trial compared adjacent segment degeneration in Bryan disc arthroplasty with that in anterior ...

journal_title：Chinese medical journal

authors： Sun Y,Zhao YB,Pan SF,Zhou FF,Chen ZQ,Liu ZJ

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVE:To review the advances of studies on vitamin D receptor and its role in the pathogenesis of diabetic nephropathy. DATA SOURCES:A comprehensive search of the PubMed literatures without restriction on the publication date was carried out using keywords such as vitamin D receptor and diabetic nephropathy. STUD...

journal_title：Chinese medical journal

authors： Guan X,Yang H,Zhang W,Wang H,Liao L

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To study the potential and advantages of internal distraction osteogenesis in mandibular functional reconstruction. METHODS:Three types of mandibular distractors were used in eight patients with various mandibular defects due to tumor or cyst resection. The average age of the patients was 31.5 years old (age...

journal_title：Chinese medical journal

authors： Wang X,Lin Y,Yi B,Wang X,Liang C,Li Z

更新日期：2002-12-01 00:00:00

abstract：:T-lymphocyte subsets, B-lymphocyte, immunoglobulins and complement were studied in 38 children with Henoch Schonlein Purpura (HSP) in the acute stage. They had significantly lower CD3 percentage and lymphocyte blastogenesis rate, greater CD8 variation coefficient and B-lymphocyte percentage and higher levels immunoglo...

journal_title：Chinese medical journal

authors： Sun XC,Chen MY,Cheng AS,Xu DL

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:Accurate evaluation of coronary artery, aortic valve annulus diameter (AVAD), and cardiac function in patients with aortic valve disease is of great significance for surgical strategy. In this study, we explored the preoperative evaluation of low-dose sequence (MinDose sequence) scan of dual-source CT (DSCT)...

journal_title：Chinese medical journal

authors： Feng J,Wang XM,Ji XP,Li HO,Li Q,Guo WB,Wang ZJ

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:It is important to determine prognostic factors for the outcome of amyotrophic lateral sclerosis (ALS) at an early stage. The time taken for symptoms to spread from spinal or bulbar regions to both (time to generalization; TTG) is considered a strong predictor of survival; however, this has rarely been studi...

journal_title：Chinese medical journal

authors： Sun QH,Li YR,Lan WJ,Yang F,Cui F,Huang XS

更新日期：2019-05-05 00:00:00

abstract：BACKGROUND:Surgical resection is generally considered the main curative treatment for intrahepatic biliary cystadenocarcinoma (IBCA) or suspected IBCAs, but controversy exists regarding the prognosis for IBCAs. This study aimed to describe the clinicopathological characteristics of IBCA and identify prognostic factors ...

journal_title：Chinese medical journal

authors： Xu MY,Shi XJ,Wan T,Liang YR,Wang HG,Zhang WZ,He L,Chen MY,Lyu SC,Zhang WW,Li HX

更新日期：2015-05-05 00:00:00

abstract：OBJECTIVE:To study the pharmacodynamics of vecuronium,atracurium, mivacurium and rocuronium in patients with end-stage renal failure. METHODS:Forty-six patients with end-stage renal failure scheduled for renal transplantation and 53 patients with normal renal function were given either vecuronium, atracurium, mivacuri...

journal_title：Chinese medical journal

authors： Ma H,Zhuang X

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:The primary reasons for local recurrence and therapeutic failure in the treatment of malignant gliomas are the invasion and interactions of tumor cells with surrounding normal brain cells. However, these tumor cells are hard to be visualized directly in histopathological preparations, or in experimental glio...

journal_title：Chinese medical journal

authors： Dong J,Dai XL,Lu ZH,Fei XF,Chen H,Zhang QB,Zhao YD,Wang ZM,Wang AD,Lan Q,Huang Q

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:As a Chinese Traditional Medicine product, Kuntai capsule could improve the peri-menopausal symptoms in postmenopausal women. But it is still not clear whether Kuntai capsule has a good effect on alleviating peri-menopausal symptoms induced by gonadotropin releasing hormone agonist (GnRH-a) treatment. The pu...

journal_title：Chinese medical journal

authors： Chen JM,Gao HY,Ding Y,Yuan X,Wang Q,Li Q,Jiang GH

更新日期：2015-02-20 00:00:00

abstract：BACKGROUND:Acute rejection is one of the most important factors for prognosis following liver transplantation. With the use of potent immunosuppressants, acute rejection does not always present typical manifestations. Moreover, other complications often occur concomitantly after liver transplantation, which makes early...

journal_title：Chinese medical journal

authors： Ma Y,Wang GD,He XS,Li JL,Zhu XF,Hu RD

更新日期：2009-06-20 00:00:00

abstract：BACKGROUND:Laparoscopic Heller cardiomyotomy and Dor fundoplication is the surgical procedure of choice for esophageal achalasia. The aim of this study was to investigate the clinical outcome of laparoscopic Heller-Dor procedure in our initial series of 25 patients with achalasia. METHODS:Between October 2003 and Janu...

journal_title：Chinese medical journal

authors： Wang QS,Liu L,Dong L,Shen ZL,Zhou DH,Hu CX

更新日期：2006-03-20 00:00:00

abstract：BACKGROUND:OX40/OX40 ligand (OX40/OX40L) and programmed death-1/programmed death ligand-1 (PD-1/PD-L1) costimulatory signals play important roles in T cell-induced immune responses. The aim of this study was to investigate the roles of OX40/OX40L and PD-1/PD-L1 costimulatory pathways in mouse islet allograft rejection....

journal_title：Chinese medical journal

authors： Li T,Ma R,Zhu J,Wang F,Huang L,Leng X

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Myocardial protection during off-pump coronary artery bypass grafting (OPCABG) is a multifactorial problem in which maintaining stable systemic hemodynamics is very important. In this study passive graft perfusion (PGP) was applied to investigate the effect during and after OPCABG as evaluated by cardiac tro...

journal_title：Chinese medical journal

authors： Lu F,Ji BY,Liu JP,Liu MZ,Wang GY,Hu SS

更新日期：2007-02-05 00:00:00

abstract：BACKGROUND:A correct thyroid function reference range is important for the accurate diagnosis of thyroid disease during pregnancy. However, there is no consensus on whether thyroid function reference ranges in Chinese population should follow the America Thyroid Association (ATA) guidelines. This study aimed to establi...

journal_title：Chinese medical journal

authors： Yang X,Meng Y,Zhang Y,Zhang C,Guo F,Yang S,Ding R,Fan JX

更新日期：2019-03-05 00:00:00

abstract：BACKGROUND:As a new electroencephalogram (EEG) signal processing technique for monitoring the depth of anesthesia, entropy consists of two indices: reaction entropy (RE) and state entropy (SE). Our study compared entropy with classical bispectral index (BIS) in reduction of myoelectrical interference and noxious stimul...

journal_title：Chinese medical journal

authors： Gao JD,Zhao YJ,Xu CS,Zhao J,Huang YG,Wang TL,Pei L,Wang J,Yao LN,Ding Q,Tan ZM,Zhu ZR,Yue Y

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:MicroRNAs (miRNAs) are highly conserved small non-coding RNAs of 18 - 25 nucleotides (nt) that mediate post-transcriptional gene regulation. Hepatitis B virus (HBV) can cause either acute or chronic hepatitis B, and is a high risk factor for liver cirrhosis and hepatocellular carcinoma. Some mammalian viruse...

journal_title：Chinese medical journal

authors： Liu Y,Zhao JJ,Wang CM,Li MY,Han P,Wang L,Cheng YQ,Zoulim F,Ma X,Xu DP

更新日期：2009-01-05 00:00:00

abstract：BACKGROUND:The potential benefit of arthroscopic surgery for osteoarthritic knee associated with medial meniscus tear is controversial. This study was conducted to determine the effect of pre-operative medial meniscus extrusion (MME) on arthroscopic surgery outcomes in the osteoarthritic knee associated with medial men...

journal_title：Chinese medical journal

authors： Wang YX,Li ZL,Li J,Zhao ZD,Wang HR,Hou C,Li W,Liu CH

更新日期：2019-11-05 00:00:00