Up-regulation of Ras/Raf/ERK1/2 signaling in the spinal cord impairs neural cell migration, neurogenesis, synapse formation, and dendritic spine development.

abstract：BACKGROUND:Liver transplantation is the most effective treatment for end-stage liver diseases; however, infections after transplantation can seriously affect the patient's health. The aim of this research was to investigate the diagnosis and treatment of fungal infection following liver transplantation. METHODS:Clinic...

journal_title：Chinese medical journal

authors： Shi XJ,Lü SC,He L,Lu F,Liang YR,Luo Y,Ji WB,Zhao ZM

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the effect of preoperative transcatheter arterial chemoembolization(TACE) on apoptosis of hepatocellular carcinoma (HCC) cells. METHODS:A total of 136 patients with HCC underwent liver resection. One to five courses of TACE prior to liver resection were performed in 79 patients (TACE group), in w...

journal_title：Chinese medical journal

authors： Xiao E,Li D,Shen S,Zhou S,Tan L,Wang Y,Luo J,Wu Y,Tan C,Liu H,Zhu H

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:Mirizzi syndrome is often difficult to diagnose before surgery, and is often accompanied by extensive adhesions in the cystohepatic (Calot's) triangle and the difficulty of separating tissue can lead to bile duct injury and other intraoperative and postoperative complications. The aim of this study is to inv...

journal_title：Chinese medical journal

authors： Li B,Li X,Zhou WC,He MY,Meng WB,Zhang L,Li YM

更新日期：2013-01-01 00:00:00

abstract：:Preeclampsia is represented by hypertension and proteinuria in pregnancy. It usually occurs after 20 gestational weeks. There are few reports on preeclampsia before 20 gestational weeks. In this case, we report a patient with chronic hypertension superimposed with preeclampsia at 13 gestational weeks. ...

journal_title：Chinese medical journal

authors： Zhu YC,Sun Y,Yang HX

更新日期：2012-06-01 00:00:00

abstract：PURPOSE:To review the current status of multimodality treatment and lymphadenectomy in the management of esophageal cancer. DATA SOURCES:Literature review. STUDY SELECTION:Multimodality treatment and lymphadenectomy in esophageal cancer. DATA EXTRACTION:Results in research papers published selected by literature sea...

journal_title：Chinese medical journal

authors： Law S,Wong J

更新日期：1997-11-01 00:00:00

abstract：:The effects of low-dose estrogen and progestogen on menopausal symptoms were studied with Kuppermen score and urinary excretion of calcium as fasting morning urine Ca/Cr ratio in 69 perimenopausal women. The subjects were divided into 3 groups: amenorrhea less than 1 year (14 women); post menopause 1-3 years (19); and...

journal_title：Chinese medical journal

authors： Lin SQ,Ge QS,Yao FY,Feng DD,Wang HL

更新日期：1990-08-01 00:00:00

abstract：OBJECTIVE:Physiologic cardiac pacing is a novel technique which has been largely popularized in recent decades. His bundle pacing (HBP) has been long considered the most physiologic pacing method; however, with the widespread implementation of this method, its disadvantages have become apparent. In this context, left b...

journal_title：Chinese medical journal

authors： Cheng LT,Zhang JM,Wang ZF,Gao HK,Wu YQ

更新日期：2019-01-20 00:00:00

abstract：BACKGROUND:The most important objective of transplant studies in the injured spinal cord has been to provide a favorable environment for axonal growth. Moreover, the continuing discovery of new grafts is providing new potentially interesting transplant candidates. Our purpose was to observe the morphological and functi...

journal_title：Chinese medical journal

authors： Chen G,Hu YR,Wan H,Xia L,Li JH,Yang F,Qu X,Wang SG,Wang ZC

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:Intermediate-risk acute myeloid leukemia (IR-AML), which accounts for a substantial number of AML cases, is highly heterogeneous. We systematically summarize the latest research progress on the significance of gene mutations for prognostic stratification of IR-AML. DATA SOURCES:We conducted a systemic search...

journal_title：Chinese medical journal

authors： Wang BH,Li YH,Yu L

更新日期：2015-09-05 00:00:00

abstract：BACKGROUND:The incidence of no reflow phenomenon limits the clinical outcomes of percutaneous coronary intervention (PCI). This randomized controlled study was designed to evaluate the immediate protective effects of intensive statin pretreatment on myocardial perfusion and myocardial ischemic injury during PCI. METHO...

journal_title：Chinese medical journal

authors： Jia XW,Fu XH,Zhang J,Gu XS,Fan WZ,Wu WL,Hao GZ,Li SQ,Jiang YF

更新日期：2009-03-20 00:00:00

abstract：OBJECTIVE:Polymorphism in vitamin D receptor (VDR) gene has been reported to play a major role in variations for genetic regulation of bone mass. Its role within various ethnic populations is not clear. The purpose of this study was to determine the frequencies of VDR genotypes in the Han and Uygur nationalities in Chi...

journal_title：Chinese medical journal

authors： Zhang H,Tao G,Wu Q,Liu J,Gao Y,Chen R,Leng X

更新日期：2000-09-01 00:00:00

abstract：OBJECTIVE:To review the relationship between personal behavior and cultural factors and reproductive tract infections (RTIs). METHODS:An English-language literature search using MEDLINE (1994-1998), Social Science Index (1994-1998), and informal discovery. Any original researches and reviews related to RTIs' epidemiol...

journal_title：Chinese medical journal

authors： Guo S

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND:Interferon-gamma release assay (IGRA) has been used in latent tuberculosis (TB) infection and TB diagnosis, but the results from different high TB-endemic countries are different. The aim of this study was to investigate the value of IGRA in the diagnosis of active pulmonary TB (PTB) in China. METHODS:We co...

journal_title：Chinese medical journal

authors： Kang WL,Wang GR,Wu MY,Yang KY,Er-Tai A,Wu SC,Geng SJ,Li ZH,Li MW,Li L,Tang SJ

更新日期：2018-02-05 00:00:00

abstract：BACKGROUND:In a previous study, we demonstrated that ephrin-A2 and -A3 negatively regulate the growth of neural progenitor cells in the central nervous system. Adult mice deficient in ephrin-A2 and -A3 (A2(-/-)A3(-/-)) displayed active ongoing neurogenesis throughout the brain, and mice deficient in ephrin-A3 alone sho...

journal_title：Chinese medical journal

authors： Zhu R,Cho KS,Chen DF,Yang L

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To provide an overview of the current knowledge of growth-differentiation factor 15 (GDF-15) in heart disease. DATA SOURCES:To identify relevant publications, we searched PubMED database combining the textual terms of heart, cardiac, cardiovascular disease with GDF-15. STUDY SELECTION:Well-controlled, relat...

journal_title：Chinese medical journal

authors： Liu HT,Wang HC,Tao L,Li CX,Li F,Zhang YY,Liu BW

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Chronic liver disease causes aberrant formation of fibrous tissue that impedes normal liver function, ultimately resulting in liver cirrhosis. Iron uptake can occur within the hepatic parenchyma or within the various nodules that form in a cirrhotic liver, termed siderotic nodules (SN). We aimed to investiga...

journal_title：Chinese medical journal

authors： Tao R,You ZL,Zhang JQ,Dai YM,Zhou DQ,Cai P,Fan Y,Cui JG,Wang J

更新日期：2012-09-01 00:00:00

abstract：:Temporary arterial occlusion during intracranial aneurysm surgery is a safe and effective modality. It is not only an emergency measure for controlling aneurysmal bleeding, but also a helpful means for accurate and meticulous dissection and clipping of an intracranial aneurysm with the advantage of minimizing the chan...

journal_title：Chinese medical journal

authors： Zhou LF,Li SQ,Yang ML

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:Vascular endothelial growth factor (VEGF) is well known as a hypoxia-induced protein. That it markedly increased expression of VEGF and improvement of rat motor function after spinal cord injury suggested that VEGF could play a neuroprotective role in ischaemic tolerance. This study investigated whether vasc...

journal_title：Chinese medical journal

authors： Ding XM,Mao BY,Jiang S,Li SF,Deng YL

更新日期：2005-10-05 00:00:00

abstract：BACKGROUND:Porcine liver performing efficient physiological functions in the human body is prerequisite for successful liver xenotransplantation. However, the protein differences between pig and human remain largely unexplored. Therefore, we investigated the liver expression profile of a highly inbred minipig line. ME...

journal_title：Chinese medical journal

authors： Chen YN,Tan WD,Lu YR,Qin SF,Li SF,Zeng YZ,Bu H,Li YP,Cheng JQ

更新日期：2007-05-05 00:00:00

abstract：BACKGROUND:The chronic obstructive pulmonary disease assessment test (CAT) is an easy to use health-related quality of life questionnaire, the modified Medical Research Council (mMRC) dyspnea scale is a classic dyspnea scale which is widely used, while the correlation between them is still not clear. This study investi...

journal_title：Chinese medical journal

authors： Zhou QT,Mei JJ,He B,Huang SG,Shi Y,Wen FQ,Zhao MW

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Acute lung injury (ALI) and end-stage acute respiratory distress syndrome (ARDS) were among the most common causes of death in intensive care units. The activation of an inflammatory response and the damage of pulmonary epithelium and endotheliumwerethe hallmark of ALI/ARDS. Recent studies had demonstrated t...

journal_title：Chinese medical journal

authors： Xu YL,Liu YL,Wang Q,Li G,Lü XD,Kong B

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:To investigate whether coagulation factor VII (FVII) polymorphisms play a role in the pathogenesis of coronary artery disease (CAD) and/or myocardial infarction (MI) in a series of Hans. METHODS:The Arg(353)Gln and HVR4 polymorphisms of FVII gene were determined in 374 patients undergoing selective coronary ...

journal_title：Chinese medical journal

authors： Xu G,Jin G,Fu G,Ma J,Shi Y,Tang O,Shan J

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Although some studies have reported that aquaporin-4 (AQP4) plays a role in the post-ischemic edema formation and diffusion-weighted imaging (DWI), little is known about the AQP4 expression in stage of the reperfusion following acute cerebral ischemia, as well as the correlation between histopathology and DW...

journal_title：Chinese medical journal

authors： Lu H,Hu H,He ZP

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Chronic graft-versus-host disease (GVHD), the commonest long-term complication after allogeneic hematopoietic stem cell transplantation (HSCT), has a negative impact on patients' health related quality of life (HRQoL). This study was designed to investigate the HRQoL in patients with chronic GVHD in China. ...

journal_title：Chinese medical journal

authors： Mo XD,Xu LP,Liu DH,Chen YH,Zhang XH,Chen H,Han W,Wang Y,Wang FR,Wang JZ,Liu KY,Huang XJ

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Robotic assisted minimally invasive cardiac sugery is a new technique that uses small port sites and peripheral vessel cannulation for cardiopulmonary bypass (CPB) has been used. The right internal jugular vein (IJV) is commonly used for intraoperative venous access to the central circulation and identified ...

journal_title：Chinese medical journal

authors： Wang Y,Wang G,Gao CQ

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of gypenosides (Gs) on cellular immunocompetence in the gamma-ray-irradiated mice. MATERIALS AND METHODS:Tested mice of ICR strain were treated continuously with Gs for 10 days before or after 4 Gy gamma-irradiation. Body weight and splenic weight of mice were measured. The blastog...

journal_title：Chinese medical journal

authors： Hau DM,Feng Y,Chen WC,Lin IH,Chen KT,Lin SS,Wang MI

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND:Endothelial dysfunction is thought to be critical events in the pathogenesis of Alzheimer's disease (AD). Endothelial progenitor cells (EPCs) have provided insight into maintaining and repairing endothelial function. To study the relation between EPCs and AD, we explored the number of circulating EPCs in pat...

journal_title：Chinese medical journal

authors： Kong XD,Zhang Y,Liu L,Sun N,Zhang MY,Zhang JN

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Myoglobin is expressed exclusively in striated skeletal muscles and has been implicated in nitric oxide scavenging. Accumulating data suggest a critical role for nitric oxide in both the endogenous and therapeutic angiogenic response to ischemia. A clear role for myoglobin in ischemic skeletal muscle is unce...

journal_title：Chinese medical journal

authors： Yang YG,Guan H,Liu CW,Li YJ

更新日期：2009-05-05 00:00:00

abstract：BACKGROUND:With the technical advances, magnetic resonance imaging (MRI) is now sensitive enough to detect subtle structural abnormalities of ocular motor nerves arising from the brainstem and orbits of living subjects. This study was designed to delineate the MRI characteristics in patients with special forms of strab...

journal_title：Chinese medical journal

authors： Jiao YH,Zhao KX,Wang ZC,Qian XH,Wu X,Man FY,Lu W,She HC

更新日期：2009-12-20 00:00:00

abstract：BACKGROUND:Chimerism analysis is an important tool for the surveillance of post-transplant engraftment. It offers the possibility of identifying impending graft rejection and recurrence of underlying malignant or non-malignant disease. Here we investigated the quantitative chimerism kinetics of 21 relapsed leukemia pat...

journal_title：Chinese medical journal

authors： Qin XY,Li GX,Qin YZ,Wang Y,Wang FR,Liu DH,Xu LP,Chen H,Han W,Wang JZ,Zhang XH,Li JL,Li LD,Liu KY,Huang XJ

更新日期：2012-06-01 00:00:00