Abstract:
PURPOSE:To review the current status of multimodality treatment and lymphadenectomy in the management of esophageal cancer. DATA SOURCES:Literature review. STUDY SELECTION:Multimodality treatment and lymphadenectomy in esophageal cancer. DATA EXTRACTION:Results in research papers published selected by literature search. RESULTS:Numerous studies have been carried out attempting to define the roles of various neoadjuvant or adjuvant regimens in the treatment of esophageal cancer. These included the use of radiotherapy or chemotherapy alone or in different combinations, with or without surgical resection. Randomized trials have failed to show significant improvement compared with surgical resection alone, although downstaging of disease and benefits on subgroups of patients could be demonstrated. Whether the extent of resection can influence outcome was tested by varying the surgical approach, and by increasing the extent of lymphadenectomy. Although indirect evidence exists suggesting more extensive resection may improve long term prognosis, definitive proof is lacking. CONCLUSIONS:More well organized randomized controlled trials are needed to further elucidate the roles of these approaches in the treatment of esophageal cancer.
journal_name
Chin Med J (Engl)journal_title
Chinese medical journalauthors
Law S,Wong Jsubject
Has Abstractpub_date
1997-11-01 00:00:00pages
819-25issue
11eissn
0366-6999issn
2542-5641journal_volume
110pub_type
杂志文章,评审abstract:BACKGROUND:Preeclampsia (PE) is a multifactorial pregnancy complication. Maternal underlying condition and adverse factors both influence the pathogenesis of PE. Abnormal lipid metabolism as a maternal underlying disease may participate in the occurrence and development of PE. This study aimed to observe the effects of...
journal_title:Chinese medical journal
pub_type: 杂志文章
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journal_title:Chinese medical journal
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journal_title:Chinese medical journal
pub_type: 杂志文章,随机对照试验
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journal_title:Chinese medical journal
pub_type: 杂志文章
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journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:1995-10-01 00:00:00
abstract:OBJECTIVE:To investigate the role of AC-cAMP system in the transmission of the action of the growth hormone releasing hormone (GRH) on growth hormone (GH) release in pituitary GH-secreting adenomas. METHODS:The effects of GRH (10(-7) mol/L) on intracellular cAMP levels and GH release and the effects of AC-cAMP stimula...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:1996-08-01 00:00:00
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journal_title:Chinese medical journal
pub_type: 杂志文章,随机对照试验
doi:10.4103/0366-6999.179783
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journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:2014-01-01 00:00:00
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journal_title:Chinese medical journal
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更新日期:2013-04-01 00:00:00
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journal_title:Chinese medical journal
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更新日期:2010-12-01 00:00:00
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journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:2011-10-01 00:00:00
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journal_title:Chinese medical journal
pub_type: 杂志文章,meta分析
doi:
更新日期:2010-11-01 00:00:00
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journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:1997-12-01 00:00:00
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journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:2003-05-01 00:00:00
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journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:2010-12-01 00:00:00
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journal_title:Chinese medical journal
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更新日期:2019-08-20 00:00:00
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journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:2012-11-01 00:00:00
abstract::To develop a more comprehensive index for predicting the prognous of liver cirrhosis. 300 consecutive patients with cirrhosis were studied in terms of survival from 1975 to 1986. Median follow-up period was 5.3 years. A multivariable survival analysis (Cox's regression model) using clinical biochemical data obtained a...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:1989-04-01 00:00:00
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pub_type: 杂志文章
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journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:2014-01-01 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章,meta分析
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更新日期:2015-07-05 00:00:00
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journal_title:Chinese medical journal
pub_type: 杂志文章,meta分析
doi:10.4103/0366-6999.195464
更新日期:2016-12-20 00:00:00
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journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:1994-04-01 00:00:00
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journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:2000-09-01 00:00:00
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journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:2010-11-01 00:00:00
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journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:1998-08-01 00:00:00