Long-term follow-up study of 72 patients with transient ischemic attacks.

abstract：BACKGROUND:Ulcerative colitis (UC) is associated with differential expression of genes involved in inflammation and tissue remodeling. MicroRNA (miRNA) plays an important role in the pathogenesis of UC by regulating the gene expression at the post-transcriptional level and control crucial physiological processes. This ...

journal_title：Chinese medical journal

authors： Min M,Peng LH,Sun G,Guo MZ,Qiu ZW,Yang YS

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:The development of new adjuvants for human use has been the focus of attention. This study's aim is to explore the possibility of using nanoparticle Ca nanoparticles (CA) as a vaccine adjuvant of anti-idiotypic antibody NP30 against schistosomiasis and its protective mechanisms. METHODS:Nanoparticle CA-NP30...

journal_title：Chinese medical journal

authors： Feng ZQ,Zhong SG,Li YH,Li YQ,Qiu ZN,Wang ZM,Li J,Dong L,Guan XH

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Chronic intermittent hypoxia (CIH) is the most important pathophysiologic feature of sleep apnea syndrome (SAS). To explore the relationship between SAS and dementia, the effects of CIH on the expression of Nip3, neuron apoptosis and beta-amyloid protein deposit in the brain cortex of the frontal lobe of mic...

journal_title：Chinese medical journal

authors： Zeng YM,Cai KJ,Chen XY,Wu MX,Lin X

更新日期：2009-01-05 00:00:00

abstract：:The effect of harringtonine (HA) in various concentrations on HL-60 was evaluated. 0.10 microgram/ml HA showed a strong cell killing effect, and 0.025 microgram/ml HA a weak differentiation induction accompanied by cell growth retardation. Differentiation induction did not occur in 5 other human leukemic cell lines. W...

journal_title：Chinese medical journal

authors： Chen SS,Wang P,Fu JY,Chen LL,Zhao FS,Shan FX

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND:Knowledge about factors influencing the prognosis of resective epilepsy surgery can be used to identify which patients are most suitable for surgical treatment. The aim of this study was to identify preoperative prognostic factors associated with the chance of achieving long-term seizure freedom. METHODS:We...

journal_title：Chinese medical journal

authors： Yang XL,Lu QC,Xu JW,Wang GS,Liu Q

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Tumor necrosis factor-α is a key mediator in the pathogenesis of psoriasis. Infliximab is a monoclonal antibody that specifically binds to tumor necrosis factor-α. The purpose of this study was to validate the efficacy and safety of 5 mg/kg infliximab therapy in Chinese patients with moderate to severe plaqu...

journal_title：Chinese medical journal

authors： Yang HZ,Wang K,Jin HZ,Gao TW,Xiao SX,Xu JH,Wang BX,Zhang FR,Li CY,Liu XM,Tu CX,Ji SZ,Shen Y,Zhu XJ

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Marked interindividual variation exists in blood pressure response to benazepril, which is considered to have genetic basis. Our objectives were to evaluate whether the E112D polymorphism in the prolylcarboxypeptidase (PRCP) gene has impact on blood pressure response to benazepril. METHODS:Hypertensive pati...

journal_title：Chinese medical journal

authors： Zhang Y,Hong XM,Xing HX,Li JP,Huo Y,Xu XP

更新日期：2009-10-20 00:00:00

abstract：OBJECTIVE:To explore the association of human leukocyte antigen (HLA) with pregnancy induced hypertension (PIH). METHODS:We oligotyped HLA-DQA1, -DQB1 locus of 30 Chinese PIH families and 14 control families in Shanghai area by polymerase chain reaction-sequence specific oligonucleotide (PCR-SSO) hybridization method ...

journal_title：Chinese medical journal

authors： Mao Y,Zhang Z,Fan L,Wu Q,Jiang L,Yang J,Yao F

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND:Surgical resection is generally considered the main curative treatment for intrahepatic biliary cystadenocarcinoma (IBCA) or suspected IBCAs, but controversy exists regarding the prognosis for IBCAs. This study aimed to describe the clinicopathological characteristics of IBCA and identify prognostic factors ...

journal_title：Chinese medical journal

authors： Xu MY,Shi XJ,Wan T,Liang YR,Wang HG,Zhang WZ,He L,Chen MY,Lyu SC,Zhang WW,Li HX

更新日期：2015-05-05 00:00:00

abstract：BACKGROUND:The CYP2C19 G681A single polymorphism has been proven to affect clopidogrel responsiveness. However, the effect of coexisting polymorphisms of other genes has not yet been reported in the Chinese population. This study investigated the effect of coexisting polymorphisms of CYP2C19 and P2Y12 on clopidogrel re...

journal_title：Chinese medical journal

authors： Tang XF,Zhang JH,Wang J,Han YL,Xu B,Qiao SB,Wu YJ,Chen J,Wu Y,Chen JL,Gao RL,Yang YJ,Yuan JQ

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:There are more than 300 genetic loci that have been found to be related to hereditary hearing impairment (HHI), including 92 causative genes for nonsyndromic hearing loss, among which 34 genes are related to autosomal dominant nonsyndromic HHI (ADNSHHI). Traditional linkage analysis and candidate gene sequen...

journal_title：Chinese medical journal

authors： Wang HY,Zhao YL,Liu Q,Yuan H,Gao Y,Lan L,Yu L,Wang DY,Guan J,Wang QJ

更新日期：2015-12-20 00:00:00

abstract：BACKGROUND:The Notch-regulated ankyrin repeat protein (NRARP) is recently found to promote proliferation of breast cancer cells. The role of NRARP in carcinogenesis deserves extensive investigations. This study attempted to investigate the expression of NRARP in thyroid cancer tissues and assess the influence of NRARP ...

journal_title：Chinese medical journal

authors： Chu BF,Qin YY,Zhang SL,Quan ZW,Zhang MD,Bi JW

更新日期：2016-07-05 00:00:00

abstract：OBJECTIVE:To investigate whether pretreatment with repeated electroacupuncture (EA) at the Baihui acupoint could induce ischemic tolerance against transient focal cerebral ischemic injury in rats. METHODS:Thirty male Sprague-Dawley (SD) rats were randomly divided into 3 groups (n=10 for each): the control group consis...

journal_title：Chinese medical journal

authors： Xiong L,Lu Z,Hou L,Zheng H,Zhu Z,Wang Q,Chen S

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Copernicus optical coherence tomography (SOCT) is a new, ultra high-speed and high-resolution instrument available for clinical evaluation of optic nerve. The purpose of the study was to compare the agreements between SOCT and Heidelberg retinal tomography (HRT). METHODS:A total of 44 healthy normal volunte...

journal_title：Chinese medical journal

authors： Yang QS,Yu YJ,Li SN,Liu J,Hao YJ

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVE:To investigate the significance of telomerase activity in urine in the diagnosis and recurrence surveillance of urothelial carcinoma. METHODS:Telomerase activity in urine of 54 cases of urothelial carcinoma (urothelial carcinoma group) was estimated by polymerase chain reaction-enzyme-linked immunosorbent as...

journal_title：Chinese medical journal

authors： Li Z,Kong C,Wang P,Liu X,Liu T

更新日期：2002-11-01 00:00:00

abstract：OBJECTIVE:To explore the relationship between apoptosis and spontaneous hypertension, and the effect of angiotensin converting enzyme (ACE) inhibitor on apoptosis. METHODS:Male spontaneously hypertensive rats (SHR) and normotensive control rats (WKY) at different ages were used, meanwhile, the treatment of SHR with ra...

journal_title：Chinese medical journal

authors： Peng L,Bradley CJ,Zulli A,Liu JJ

更新日期：1999-06-01 00:00:00

abstract：:The protective effect of improving the microcirculation on the retinal ganglion cells (RGC) and the ultrastructure of the optic nerve after intravenous (i.v.) use of Salviae miltiorrhiza (SMR) was studied in a chronic intraocular hypertension model in 36 rabbits. These rabbits were treated with topical 0.5% timolol, o...

journal_title：Chinese medical journal

authors： Zhu MD,Cai FY

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:The baseline characteristics of patients in a multinational trial are possibly related to cardiovascular outcome. This study compared the baseline characteristics of patients recruited in China with those recruited in other countries. METHODS:A total of 508 Chinese hypertensive men and 728 women over the ag...

journal_title：Chinese medical journal

authors： Liu LS,Wang JG,Shu-Ping M,Wang W,Lu FH,Zhang LQ,Banya W,Peters R,Beckett N,Fletcher A,Bulpitt CJ

更新日期：2008-08-20 00:00:00

abstract：: ...

journal_title：Chinese medical journal

authors： Zhu W,Zhang LJ,Jiang C,Weng XS

更新日期：2018-11-05 00:00:00

abstract：BACKGROUND:L-shaped incision of pronator quadratus (PQ) muscle along its radial and distal borders was always taken for distal radius fractures reduction and internal fixation. Repair of the PQ muscle was always recommended at the end of operation for some instructive reasons. But repair of PQ is not satisfied because ...

journal_title：Chinese medical journal

authors： Fan J,Chen K,Zhu H,Jiang B,Yuan F,Zhu X,Mei J,Yu G

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:In many studies, obstructive sleep apnea (OSA) has been shown to be an independent risk factor for cardiovascular disease. Conversely, there are few reports establishing possible relation between OSA and venous thromboembolism (VTE). In this study, the aim is to evaluate OSA via polysomnography in patients w...

journal_title：Chinese medical journal

authors： Kezban OS,Ali NA,Umran T,Talha D,Ege GB,Peri A,Leyla YA,Hasan S

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Precise evaluation of the live donor's liver is the most important factor for the donor's safety and the recipient's prognosis in living donor liver transplantation (LDLT). Our study assessed the clinical value of computer-assisted three-dimensional quantitative assessment and a surgical planning tool for do...

journal_title：Chinese medical journal

authors： Wei L,Zhu ZJ,Lü Y,Jiang WT,Gao W,Zeng ZG,Shen ZY

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Preeclampsia (PE) is a multifactorial pregnancy complication. Maternal underlying condition and adverse factors both influence the pathogenesis of PE. Abnormal lipid metabolism as a maternal underlying disease may participate in the occurrence and development of PE. This study aimed to observe the effects of...

journal_title：Chinese medical journal

authors： Ding X,Yang Z,Han Y,Yu H

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) is a growing public health problem with well-established risk factors. Other contributing factors, however, remain to be identified. Systemic inflammation in asthma plays a significant role in the development of other diseases. We therefore initiated a study to assess whether the...

journal_title：Chinese medical journal

authors： Liu DW,Zhen XG,Liang Y,Jing XG,Zhang TS,Zhang GJ,Liu ZS

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Phosphorous magnetic resonance spectroscopy ((31)P-MRS) has been successfully applied to study intracellular membrane compounds and high-energy phosphate metabolism. This study aimed to evaluate the capability of dynamic (31)P-MRS for assessing energy metabolism and mitochondrial function in skeletal muscle ...

journal_title：Chinese medical journal

authors： Wu FY,Tu HJ,Qin B,Chen T,Xu HF,Qi J,Wang DH

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Retroperitoneal sarcoma is a rare disease with poor prognosis. The aim of this study was to investigate the prognostic factors of the disease. METHODS:Between January 1988 and December 2003, 132 patients with retroperitoneal sarcoma were surgically treated in our hospital, 79 of them were followed up for 1 ...

journal_title：Chinese medical journal

authors： Chen CQ,Yin L,Peng CH,Cai Y,Li YF,Zhao R,Zhou HJ,Li HW

更新日期：2007-06-20 00:00:00

abstract：BACKGROUND:Epinephrine has been used as a first-choice vasopressor drug for cardiac arrest (CA) since 1974. However, the administration of epinephrine is controversial. This study aims to compare the effects of Shen-Fu injection (SFI) and epinephrine on resuscitation outcomes in a porcine model of prolonged CA. METHOD...

journal_title：Chinese medical journal

authors： Yin W,Guo Z,Li C

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:Parkinson's disease (PD) is featured with motor disorder and nonmotor manifestations including psychological symptoms, autonomic nervous system dysfunction, and paresthesia, which results in great inconvenience to the patients' life. The apolipoprotein (Apo) superfamily, as a group of potentially modifiable b...

journal_title：Chinese medical journal

authors： Li L,Liu MS,Li GQ,Tang J,Liao Y,Zheng Y,Guo TL,Kang X,Yuan MT

更新日期：2017-11-05 00:00:00

abstract：BACKGROUND:Congenital uterine anomalies are associated with the highest incidence of reproductive failure and obstetric complications. This study aimed to summarize the clinical characteristics and prenatal outcome of pregnancy in women with congenital uterine malformations. METHODS:This retrospective study evaluated ...

journal_title：Chinese medical journal

authors： Zhang Y,Zhao YY,Qiao J

更新日期：2010-02-20 00:00:00

abstract：OBJECTIVE:To evaluate the roles of folic acid and beta-carotene in the chemoprevention of gastric and other gastrointestinal (GI) cancers. METHODS:In a randomized, double-blind, placebo-controlled trial, a total of 216 patients with atrophic gastritis were randomly assigned to one of the four groups: (1) folate (FA, 2...

journal_title：Chinese medical journal

authors： Zhu S,Mason J,Shi Y,Hu Y,Li R,Wahg M,Zhou Y,Jin G,Xie Y,Wu G,Xia D,Qian Z,Sohg H,Zhang L,Russell R,Xiao S

更新日期：2003-01-01 00:00:00