Antileukemic effect of low-dose harringtonine.

abstract：BACKGROUND:The decreased degradation of extra-cellular matrix proteins plays an important role in the onset of diabetic nephropathy. Matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of metalloproteinase-1 (TIMP-1), which are members of the matrix metalloproteinase family, are associated with this process. Angiot...

journal_title：Chinese medical journal

authors： Ding HL,Guo Y,Xu MT,Li HY,Fu ZZ

更新日期：2007-11-05 00:00:00

abstract：BACKGROUND:Intensive treatment such as autologous peripheral blood stem cell (PBSC) transplantation is an important therapeutic strategy in many hematologic malignancies. A number of factors have been reported to impact PBSC mobilization, but the predictive factors varied from one study to another. This retrospective s...

journal_title：Chinese medical journal

authors： Yang SM,Chen H,Chen YH,Zhu HH,Zhao T,Liu KY

更新日期：2012-02-01 00:00:00

abstract：OBJECTIVE:To study the preventive effect of artemether (Art) in protecting the people from schistosome infection during flood fighting in schistosomiasis endemic area of Poyang Lake, Jiangxi Province. METHODS:From mid July to mid August in 1996, the water level in Poyang Lake rose due to torrential rains and 2 embankm...

journal_title：Chinese medical journal

authors： Song Y,Xiao S,Wu W,Zhang S,Xie H,Xu X,Hu X,Cui Q,Chen M,Zheng J

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND:The 2019 novel coronavirus has caused the outbreak of the acute respiratory disease in Wuhan, Hubei Province of China since December 2019. This study was performed to analyze the clinical characteristics of patients who succumbed to and who recovered from 2019 novel coronavirus disease (COVID-19). METHODS:C...

journal_title：Chinese medical journal

authors： Deng Y,Liu W,Liu K,Fang YY,Shang J,Zhou L,Wang K,Leng F,Wei S,Chen L,Liu HG

更新日期：2020-06-05 00:00:00

abstract：BACKGROUND:Ulcerative colitis (UC) is associated with differential expression of genes involved in inflammation and tissue remodeling. MicroRNA (miRNA) plays an important role in the pathogenesis of UC by regulating the gene expression at the post-transcriptional level and control crucial physiological processes. This ...

journal_title：Chinese medical journal

authors： Min M,Peng LH,Sun G,Guo MZ,Qiu ZW,Yang YS

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Studies on selected patients undergoing off-pump versus on-pump coronary artery bypass surgery have produced inconsistent results, especially in patients with multiple coronary artery disease. This study compared the clinical results of on-pump and off-pump coronary bypass surgery in patients with triple-ves...

journal_title：Chinese medical journal

authors： Chen X,Xu M,Shi HW,Mu XW,Chen ZQ,Qiu ZB

更新日期：2004-03-01 00:00:00

abstract：:Psoralen (PSO) was found cytotoxic against in vitro cultured human mucoepidermoid carcinoma cells of MEC-1 cell line. Its IC50 value was 8.6 micrograms/ml, and relative antitumor activity (RAA) 15. PSO suppressed DNA synthesis, damaged microvilli and cell membrane, and induced degeneration of mitochondria. It inhibite...

journal_title：Chinese medical journal

authors： Wu JZ,Situ ZQ,Wang W,Chen JY,Liu B

更新日期：1992-11-01 00:00:00

abstract：OBJECTIVE:To investigate the effectiveness of using continuous veno venous hemofiltration (CVVH) in the treatment of acute necrotizing pancreatitis (ANP). METHODS:Thirteen ANP patients were involved in this study, including 4 females and 9 males, averaging 50.6 +/- 10.8 years old. CT scans upon admission revealed 33% ...

journal_title：Chinese medical journal

authors： Xie H,Ji D,Gong D,Liu Y,Xu B,Zhou H,Liu Z,Li L,Li W,Quan Z,Li J

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVE:To clarify the role of these cyclins in human gastric cancer. METHODS:38 gastric cancer patients, 29 first degree relatives of gastric cancer patients, as well as 18 healthy subjects were included. The mRNA expression of cyclins D1, D2, D3 and E in gastric biopsies was evaluated by RT-PCR analysis using spec...

journal_title：Chinese medical journal

authors： Yu J,Miehlke S,Ebert MP,Szokodi D,Wehvnignh B,Malfertheiner P,Ehninger G,Bayerdoerffer E

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:Pancreatic beta-cell apoptosis induced by lipotoxicity, to a large extent, contributes to the progression of type 2 diabetes. To investigate the mechanism of free fatty acid induced apoptosis, we aimed to study the effects of palmitic acid (PA) on the apoptosis and peroxisome proliferator-activated receptor ...

journal_title：Chinese medical journal

authors： He TT,Cao XP,Chen RZ,Zhu XN,Wang XL,Li YB,Xiao HP

更新日期：2011-11-01 00:00:00

abstract：:102 patients with nasal polyps receiving ND: YAG laser surgery or routine surgery were followed up for 18-36 months. The postoperative recurrence rates were 40.6% (24/54) and 66.6% (32/48) respectively for the patients of the two groups. Laser surgery is marked by less bleeding, no postoperative packing of the nose an...

journal_title：Chinese medical journal

authors： Zhang BQ

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND:Whether antibody to myelin oligodendrocyte glycoprotein (MOG) can be a diagnostic marker for multiple sclerosis (MS) is still controversial. Recent studies suggested that serum specific anti-MOG epitope antibody might be an MS specific marker. However, these studies did not include neuromyelitis optica (NMO)...

journal_title：Chinese medical journal

authors： Xu Y,Zhang Y,Liu CY,Peng B,Wang JM,Zhang XJ,Li HF,Cui LY

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Aquaporin-1 (AQP1) has involved in fluid transport in diverse pulmonary edema diseases. Our study aimed to explore the dynamic changes of AQP1 in pulmonary water metabolism in rats following traumatic brain injury (TBI) and the protective effect provided by shenmai injection. METHODS:Sixty male Sprague Dawl...

journal_title：Chinese medical journal

authors： Bai Y,Yao HX,Hu ML,Wang LR,Jin LD,Wang WT,Lin LN

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVE:To focus on the asthmatic pathogenesis and clinical manifestations related to epithelial sodium channel (ENaC)/chlorine ion channel. DATA SOURCES:The data analyzed in this review were the English articles from 1980 to 2015 from journal databases, primarily PubMed and Google Scholar. The terms used in the lit...

journal_title：Chinese medical journal

authors： Wang W,Ji HL

更新日期：2015-08-20 00:00:00

abstract：OBJECTIVE:To investigate the feasibility and features of 3 catheter-mediated approaches of gene transfer into heart, including direct myocardial injection (DMI), coronary artery perfusion (CAP), and intrapericardial cavity injection (ICI). METHODS:Fifteen dogs were used, and 0.3 ml (1 x 10(9) pfu) of an adenovirus (Ad...

journal_title：Chinese medical journal

authors： Li J,Li G,Huang C,Jiang H,Tang Q,Xu J,Xia H,Wang J

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:Early neurological deterioration (END) is a prominent issue after recanalization treatment. However, few studies have reported the characteristics of END after endovascular treatment (EVT) as so far. This study investigated the incidence, composition, and outcomes of END after intravenous recombinant tissue ...

journal_title：Chinese medical journal

authors： Zhang YB,Su YY,He YB,Liu YF,Liu G,Fan LL

更新日期：2018-01-20 00:00:00

abstract：:We presented the experimental results of endothelial cells (EC) seeding in small caliber interpositional dacron grafts of canine carotid arteries. Six weeks after surgery, 9 (56.25%) seeded, and 6 (37.5%) control grafts remained patent. The mean thrombus-free surface area was 83.4% in the seeded and 62% in the control...

journal_title：Chinese medical journal

authors： Wang ZG,Zhang H

更新日期：1989-08-01 00:00:00

abstract：:Twenty-one patients, under 6 years of age, with root avulsion of the brachial plexus were treated from 1975 to 1987. Among them, 9 had root avulsion of the upper trunk, 2 root avulsion of the lower trunk with middle trunk broken, and 10 root avulsion of the whole brachial plexus. Follow-up of 16 patients showed excell...

journal_title：Chinese medical journal

authors： Zhang GM,Gu YD,Chen DS,Yan JG,Cheng XM

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND:A correct thyroid function reference range is important for the accurate diagnosis of thyroid disease during pregnancy. However, there is no consensus on whether thyroid function reference ranges in Chinese population should follow the America Thyroid Association (ATA) guidelines. This study aimed to establi...

journal_title：Chinese medical journal

authors： Yang X,Meng Y,Zhang Y,Zhang C,Guo F,Yang S,Ding R,Fan JX

更新日期：2019-03-05 00:00:00

abstract：ABSTRACT:Cerebral small vessel disease (SVD) is a common global brain disease that causes cognitive impairment, ischemic or hemorrhagic stroke, problems with mobility, and neuropsychiatric symptoms. The brain damage, seen as focal white and deep grey matter lesions on brain magnetic resonance imaging (MRI) or computed ...

journal_title：Chinese medical journal

authors： Clancy U,Appleton JP,Arteaga C,Doubal FN,Bath PM,Wardlaw JM

更新日期：2020-10-06 00:00:00

abstract：OBJECTIVE:To study whether liver cirrhosis associated with Helicobacter pylori (H. pylori) infection will induce increased serum ammonia and whether the peripheral serum ammonia reflects the level of portal vein serum ammonia. METHODS:Blood was taken from the portal vein and the cubital vein in cirrhotic patients with...

journal_title：Chinese medical journal

authors： Si J,Cao Q,Gao M,Fang L,Qian G,Wang Y

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND:Human umbilical cord blood-derived mesenchymal stem cells (UCB-MSCs) could be induced to differentiate into insulin producing cells (IPCs) in vitro, which have good application potential in the cell replacement treatment of type-1 diabetes. However, the mechanisms regulating this differentiation have remaine...

journal_title：Chinese medical journal

authors： Hu YH,Wu DQ,Gao F,Li GD,Zhang XC

更新日期：2010-03-05 00:00:00

abstract：BACKGROUND:Ilexonin A (IA), purified from the Chinese herbal medicine Maodongqing (Ilex pubescens Hook, et Arn) has been commonly used in south China to treat thrombotic disorders. In this study, we aimed to study the inhibiting effects and mechanism of IA on von Willebrand factor (vWF)-dependent high shear-induced pla...

journal_title：Chinese medical journal

authors： Li M,Wu WK,Liu L,Liao FL,Shinohara Y,Handa S,Goto S

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:It is now recognized that Cimicifuga foetida (C. foetida) extract is effective in alleviating menopausal symptoms. But the durations reported were usually short. The aim of this study was to investigate the effects of C. foetida extract therapy and different estrogen and progesterone sequential therapies, on...

journal_title：Chinese medical journal

authors： Gaowa S,Sun AJ,Jiang Y,He FW,Zheng TP,Wang YP

更新日期：2015-04-20 00:00:00

abstract：OBJECTIVE:To study the experience in the treatment of subclavian steal syndrome (SSS) and the relation between SSS and the damage of brain. METHODS:In 28 patients with SSS, 23 were operated on. They complained of vertigo, TIA, and claudication of arms. One patient suffered from severe stem ischemia spasm. All the pati...

journal_title：Chinese medical journal

authors： Guan H,Liu C,Yu Z

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND:The potential benefit of arthroscopic surgery for osteoarthritic knee associated with medial meniscus tear is controversial. This study was conducted to determine the effect of pre-operative medial meniscus extrusion (MME) on arthroscopic surgery outcomes in the osteoarthritic knee associated with medial men...

journal_title：Chinese medical journal

authors： Wang YX,Li ZL,Li J,Zhao ZD,Wang HR,Hou C,Li W,Liu CH

更新日期：2019-11-05 00:00:00

abstract：OBJECTIVE:The purpose of this study was to demonstrate the lumbar pedicle cortical bone trajectory (CBT) screw fixation technique, a new fixation technique for lumbar surgery. DATA SOURCES:The data analyzed in this review are mainly from articles reported in PubMed published from 1994 to 2014. STUDY SELECTION:Origina...

journal_title：Chinese medical journal

authors： Song T,Hsu WK,Ye T

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Respiratory failure caused by metastatic pulmonary choriocarcinoma usually develops rapidly and is associated with a high mortality. The clinical management strategy is important in choriocarcinoma patients with acute respiratory failure. The objective of this study was to evaluate the clinical characteristi...

journal_title：Chinese medical journal

authors： Shen Y,Ren T,Feng FZ,Wan XR,Xiang Y

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Diabetic lower limb ischemia is a serious complication of diabetes mellitus. This study was conducted to investigate the effectiveness of distal arterial bypass treatment in diabetic patients with lower limb ischemia. METHODS:From July 2000 to July 2004, 96 lower limbs of 82 diabetic patients (type 2) with ...

journal_title：Chinese medical journal

authors： Gu YQ,Zhang J,Qi LX,Yu HX,Li JX,Li XF,Guo LR,Luo T,Cui SJ,Wang ZG

更新日期：2007-01-20 00:00:00

abstract：BACKGROUND:Human epididymis secretory protein 4 (HE4) is a new ovarian cancer biomarker. The factors influencing HE4 levels are not clear, and the reference data in China are limited. Here, we aim to evaluate the effects of menopause and age on HE4 levels and to provide a possible reference value for HE4 in healthy Chi...

journal_title：Chinese medical journal

authors： Cheng HY,Zeng L,Ye X,Ma RQ,Tang ZJ,Chu HL,Zhao YM,Zhu LR,Gao YN,Chang XH,Cui H

更新日期：2020-06-05 00:00:00