Comparative study of optic disc measurement by Copernicus optical coherence tomography and Heidelberg retinal tomography.

abstract：OBJECTIVE:To measure serum 7S collagen (7S-C) and type VI collagen (VI-C) levels by radioimmunoassay (RIA) in Chinese patients with various liver disorders and in CCl4-treated SD rats, and to investigate the significance of the elevated levels of serum 7S-C and VI-C. METHODS:Serum 7S-C and VI-C levels were measured in...

journal_title：Chinese medical journal

authors： Ji X,Li S,Kong X,Xu G,Chen J,Dai X

更新日期：1997-03-01 00:00:00

abstract：OBJECTIVE:To investigate the mechanism of multidrug resistance (MDR) in a human glioma cell and methods for overcoming multi-drug resistance. METHODS:MDR cell line C(6)/adr was established. The expression of the mdr-1 gene and its P-glycoprotein (P-gp) in the C(6)/adr cell line was observed by RT-PCR and flow cytometr...

journal_title：Chinese medical journal

authors： Liu F,Wang C,Zhang Q,Li J,Zhang Y

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:Atrial natriuretic peptide (ANP) and its natriuretic peptide receptors A (NPR-A) and C (NPR-C) are involved in the regulation of physiological and pathophysiological process of blood pressure. The present study aimed to determine the role of NPR-C in the development of salt-sensitive hypertension. METHODS:T...

journal_title：Chinese medical journal

authors： Zhu XL,Zhang T,Xu ZQ,Ma XC,Wang ZJ,Zou CW,Li JX,Jing HY

更新日期：2020-05-20 00:00:00

abstract：OBJECTIVE:To assess the existence of a possible infectious factor in varicocele-related infertility. METHODS:A total of 925 seminal plasmas from 590 infertile men with varicocele and 335 infertile patients without palpable varicocele were cultured for Ureaplasma urealyticum infection, and routine semen analysis was ma...

journal_title：Chinese medical journal

authors： Li H,Guo Y,Wang Y,Sun X

更新日期：1997-11-01 00:00:00

abstract：BACKGROUND:Orthostatic intolerance (OI) is a common disease at pediatric period which has a serious impact on physical and mental health of children. The purpose of this study was to investigate the effect of related factors on the prognosis of children with OI. METHODS:The subjects were 170 children with OI, includin...

journal_title：Chinese medical journal

authors： Li Y,Li H,Li X,Li X,Jin H

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To investigate the synergistic antitumor effects of combined use of p14ARF gene and 5-fluorouracil (5-Fu) in pancreatic cancer. METHODS:A human pancreatic cancer cell line PC-3 was transfected with lipofectin-mediated recombinant p14ARF gene, and was then administered with 5-Fu. Cell growth, morphological ch...

journal_title：Chinese medical journal

authors： Zhang Q,Ni Q,Gan J,Shen Z,Luo J,Jin C,Zhang N,Zhang Y

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Glaucoma can cause progressive damage to retinal ganglion cells. These cells can be classified as cells projecting to the superior colliculus and melanopsin-containing retinal ganglion cells, which project to the suprachiasmatic nucleus. This study was to investigate the effects of chronic intraocular pressu...

journal_title：Chinese medical journal

authors： Wang HZ,Lu QJ,Wang NL,Liu H,Zhang L,Zhan GL

更新日期：2008-06-05 00:00:00

abstract：BACKGROUND:The side effects of cyclosporine therapy include thromboembolic complications. However, the mechanisms underlying the hypercoagulable state induced by cyclosporine are not fully understood. Cyclosporine binds to red blood cells (RBCs) with a high affinity in circulation and alters the membranes of RBCs. Ther...

journal_title：Chinese medical journal

authors： Zheng YN,Yu HJ,Hou JX,Lu CF,Zhou J

更新日期：2009-07-20 00:00:00

abstract：BACKGROUND:Previous studies demonstrated general anesthetics affect potassium ion channels, which may be one of the mechanisms of general anesthesia. Because the effect of etomidate on potassium channels in rat hippocampus which is involved in memory function has not been studied, we investigated the effects of etomida...

journal_title：Chinese medical journal

authors： Tan HY,Sun LN,Wang XL,Ye TH

更新日期：2010-03-20 00:00:00

abstract：BACKGROUND:A correct thyroid function reference range is important for the accurate diagnosis of thyroid disease during pregnancy. However, there is no consensus on whether thyroid function reference ranges in Chinese population should follow the America Thyroid Association (ATA) guidelines. This study aimed to establi...

journal_title：Chinese medical journal

authors： Yang X,Meng Y,Zhang Y,Zhang C,Guo F,Yang S,Ding R,Fan JX

更新日期：2019-03-05 00:00:00

abstract：BACKGROUND:Intravertebral and general anesthesia (GA) are two main anesthesia approaches but both have defects. This study was aimed to evaluate the effect of subarachnoid anesthesia combined with propofol target-controlled infusion (TCI) on blood loss and transfusion for total hip arthroplasty (THA) in elderly patient...

journal_title：Chinese medical journal

authors： Xu CS,Qu XD,Qu ZJ,Wang G,Wang HJ

更新日期：2020-03-20 00:00:00

abstract：OBJECTIVE:To investigate whether pretreatment with repeated electroacupuncture (EA) at the Baihui acupoint could induce ischemic tolerance against transient focal cerebral ischemic injury in rats. METHODS:Thirty male Sprague-Dawley (SD) rats were randomly divided into 3 groups (n=10 for each): the control group consis...

journal_title：Chinese medical journal

authors： Xiong L,Lu Z,Hou L,Zheng H,Zhu Z,Wang Q,Chen S

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of the combination of octreotide and aspirin on the growth of gastric cancer. METHODS:Proliferation of gastric cancer cell lines treated with octreotide or aspirin was determined by (3)H-thymidine incorporation. After xenografts of human gastric cancer were implanted orthotopically...

journal_title：Chinese medical journal

authors： Tang C,Wang C,Tang L

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:Pulsed radiofrequency (PRF) is a minimally invasive interventional technique that provides a novel and effective treatment strategy for neuropathic pain (NP). PRF is advantageous because it does not damage nerves and avoids sensory loss after treatment. At present, animal studies have demonstrated that PRF i...

journal_title：Chinese medical journal

authors： Fu M,Meng L,Ren H,Luo F

更新日期：2019-07-20 00:00:00

abstract：BACKGROUND:Using tissue Doppler imaging and conventional echocardiographic technique, we examined the cardiac function and synchronicity in individuals with isolated right bundle branch block (RBBB) or left bundle branch block (LBBB) and assessed the relationship between QRS duration and synchronicity. METHODS:Subject...

journal_title：Chinese medical journal

authors： Niu HX,Hua W,Zhang S,Sun X,Wang FZ,Chen KP,Wang H,Chen X

更新日期：2006-05-20 00:00:00

abstract：OBJECTIVE:To study whether human umbilical cord blood CD34+ cells transduced with human aldehyde dehydrogenase class-1 (ALDH-1) and multidrug resistance gene (MDR1) have increases resistance to 4-Hydroperoxycyclo-phosphamide (4-HC) and P-glycoprotein effluxed drugs. METHODS:A bicistronic retroviral vector G1Na-ALDH1-I...

journal_title：Chinese medical journal

authors： Wang J,Chen Z,Xia X,Lu D,Xue J,Ruan C

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Tbx1 is the major candidate gene for DiGeorge syndrome (DGS). Similar to defects observed in DGS patients, the structures disrupted in Tbx1(-/-) animal models are derived from the neural crest cells during development. Although the morphological phenotypes of some Tbx1 knock-down animal models have been well...

journal_title：Chinese medical journal

authors： Zhang LF,Gui YH,Wang YX,Jiang Q,Song HY

更新日期：2010-05-05 00:00:00

abstract：:With monoclonal antibodies serum immunoglobulin G(IgG) subclasses were measured in seventy children aged 2 to 13 years with recurrent respiratory tract infections including upper respiratory tract infections, otitis media, sinusitis, asthmatic bronchitis and pneumonia. 211 healthy, aged-matched children served as cont...

journal_title：Chinese medical journal

authors： Jiang LP,Yang XQ,Li CR,Zhang YW,Wang LJ,Shen J

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:Myocardial apoptosis is involved in the pathogenesis of sepsis-related myocardial depression. However, the underlying mechanism remains unknown. This study investigated the role of mitochondrial damage and mitochondria-induced oxidative stress during cardiac apoptosis in septic rats. METHODS:Seventy-two Spr...

journal_title：Chinese medical journal

authors： Li L,Hu BC,Chen CQ,Gong SJ,Yu YH,Dai HW,Yan J

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:The long-term safety and efficacy of drug-eluting stents (DES) versus bare metal stents (BMS) are unclear and controversial issues in patients with acute ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI). The purpose of this study was to compare the long-t...

journal_title：Chinese medical journal

authors： Wang CH,Fang Q,Zhang SY,Shen ZJ,Fan ZJ,Jin XF,Zeng Y,Liu ZY,Xie HZ,Yang M

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Drug treatment for secondary hyperparathyroidism caused by chronic renal failure may be available at the early stage of the disease, but it is not as effective for serious patients. The aim of the study was to evaluate the effect of total parathyroidectomy combined with forearm autotransplantation in the ure...

journal_title：Chinese medical journal

authors： Zou Q,Wang HY,Zhou J,Lao ZY,Xue J,Li MX,Li HM,Jin YT,Gu Y,Zhang YL

更新日期：2007-10-20 00:00:00

abstract：:Preeclampsia is represented by hypertension and proteinuria in pregnancy. It usually occurs after 20 gestational weeks. There are few reports on preeclampsia before 20 gestational weeks. In this case, we report a patient with chronic hypertension superimposed with preeclampsia at 13 gestational weeks. ...

journal_title：Chinese medical journal

authors： Zhu YC,Sun Y,Yang HX

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Zika virus (ZIKV) has emerged as a global pathogen causing significant public health concerns. China has reported several imported cases where ZIKV were carried by travelers who frequently travel between China and ZIKV-endemic regions. To fully characterize the ZIKV strains isolated from the cases reported i...

journal_title：Chinese medical journal

authors： Liu RF,He ZJ,Mei P,Xi JC,Cao XD,Yuan LH,Lu JH

更新日期：2019-07-20 00:00:00

abstract：:Microencapsules for pituitary transplantation was successfully developed with sodium alginate and poly-L-lysine (average molecular weight MW 70,000). The permeability of the capsular membrane (CM) was tested. The results showed that 60% of growth hormone (GH), thyroid stimulating hormone (TSH), prolactin (PRL) have pa...

journal_title：Chinese medical journal

authors： Chen ZP,Bao YD

更新日期：1994-03-01 00:00:00

abstract：BACKGROUND:Na + /Ca 2+ exchanger (NCX) plays a crucial role in pentylenetetrazol-induced convulsion. However, it is unclear whether NCX is critically involved in hyperthermia-induced convulsion. In this study, we examined the potential changes in NCX3 in the hippocampus and cerebrocortex of rats with hyperthermia-induc...

journal_title：Chinese medical journal

authors： Sun D,Xiao JH,Bai Y,Chen MS,Hu JS,Wu GF,Mao B,Wu SH,Hu Y

更新日期：2015-11-20 00:00:00

abstract：OBJECTIVE:To determine whether mutation of the coding or junction region of glucokinase gene (GCK) is also the pathogenic cause of the common form of non-insulin-dependent diabetes mellitus (NIDDM) in Chinese. METHODS:Single strand conformation polymorphism (SSCP) analysis was performed after the 12 exons and junction...

journal_title：Chinese medical journal

authors： Xiang K,Wu S,Zheng T,Sun D,Wang Y,Pu L

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND:The anterior cruciate ligament (ACL) is one of the most commonly injured knee ligaments. Even following ACL reconstruction, significant articular cartilage degeneration can be observed and most patients suffer from premature osteoarthritis. Articular cartilage degeneration and osteoarthritis development afte...

journal_title：Chinese medical journal

authors： Shi DL,Wang YB,Ai ZS

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:The Dynamic Interspinous Assisted Motion (DIAM) system was designed to stabilize degenerative spinal segments without fusion surgery, maintain segment motion and prevent adjacent segment degeneration. The aim of this study was to investigate clinical efficacy of the DIAM system in treatment of degenerative l...

journal_title：Chinese medical journal

authors： Zhao Y,Wang YP,Qiu GX,Zhao H,Zhang JG,Zhou X

更新日期：2010-11-01 00:00:00

abstract：Objective:Since the advent of induced pluripotent stem cell (iPSC) technology a decade ago, enormous progress has been made in stem cell biology and regenerative medicine. Human iPSCs have been widely used for disease modeling, drug discovery, and cell therapy development. In this review, we discuss the progress in app...

journal_title：Chinese medical journal

authors： Wang F,Kong J,Cui YY,Liu P,Wen JY

更新日期：2018-04-05 00:00:00

abstract：BACKGROUND:L-shaped incision of pronator quadratus (PQ) muscle along its radial and distal borders was always taken for distal radius fractures reduction and internal fixation. Repair of the PQ muscle was always recommended at the end of operation for some instructive reasons. But repair of PQ is not satisfied because ...

journal_title：Chinese medical journal

authors： Fan J,Chen K,Zhu H,Jiang B,Yuan F,Zhu X,Mei J,Yu G

更新日期：2014-01-01 00:00:00