Abstract:
:Cellular and humoral immune functions in Chinese hemophiliacs with and without human immunodeficiency virus (HIV) infection were compared with those of healthy controls. There was a significant increase in peripheral T8 cells and a significant decrease of peripheral T4 cells as well as the T4/T8 ratio in 3 hemophiliacs with HIV infection when compared with 26 hemophiliacs without HIV infection and 18 healthy controls (P less than 0.005, P less than 0.05 and P less than 0.002, respectively). In contrast, there were no statistical differences in the above mentioned parameters between hemophiliacs without HIV infection and healthy controls. All the three HIV seropositive hemophiliacs had anergy for 1:2000 OT test whereas among the 15 HIV seronegative hemophiliacs, only two had anergy for 1:2000 OT test. These results demonstrate that the immunological abnormalities of the 3 HIV seropositive hemophiliacs were attributed to HIV infection, and that even though hemophiliacs without HIV infection had been treated with blood products, their immune functions are generally normal. These findings are somewhat different from those reported abroad. This difference may be due to the fact that Chinese hemophiliacs are often treated with much smaller dose of blood products as a part of the treatment of their coagulative defects.
journal_name
Chin Med J (Engl)journal_title
Chinese medical journalauthors
Tang DJ,Pang XGsubject
Has Abstractpub_date
1991-10-01 00:00:00pages
803-7issue
10eissn
0366-6999issn
2542-5641journal_volume
104pub_type
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journal_title:Chinese medical journal
pub_type: 杂志文章
doi:10.4103/0366-6999.225056
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journal_title:Chinese medical journal
pub_type: 杂志文章,meta分析
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pub_type: 杂志文章
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pub_type: 杂志文章,评审
doi:10.4103/0366-6999.163400
更新日期:2015-09-05 00:00:00
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journal_title:Chinese medical journal
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更新日期:2011-12-01 00:00:00
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journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:2009-10-20 00:00:00
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journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
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pub_type: 杂志文章
doi:10.4103/0366-6999.161343
更新日期:2015-08-05 00:00:00
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journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:2010-02-05 00:00:00
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journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:1991-03-01 00:00:00
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journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:2012-01-01 00:00:00
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journal_title:Chinese medical journal
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1995-11-01 00:00:00
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pub_type: 杂志文章
doi:
更新日期:2003-02-01 00:00:00
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doi:
更新日期:2000-11-01 00:00:00
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journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:1999-11-01 00:00:00
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pub_type: 杂志文章
doi:
更新日期:1992-11-01 00:00:00
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pub_type: 杂志文章
doi:
更新日期:1994-04-01 00:00:00
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journal_title:Chinese medical journal
pub_type: 杂志文章,meta分析,评审
doi:
更新日期:2014-01-01 00:00:00
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journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:1993-02-01 00:00:00
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pub_type: 杂志文章
doi:
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pub_type: 杂志文章
doi:
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pub_type: 杂志文章
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pub_type: 杂志文章
doi:
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pub_type: 杂志文章
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更新日期:2017-07-20 00:00:00
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journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:2005-04-20 00:00:00
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pub_type: 杂志文章
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更新日期:2020-10-20 00:00:00
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journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:1999-09-01 00:00:00
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journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:2004-05-01 00:00:00
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journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:1989-03-01 00:00:00
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journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:2004-04-01 00:00:00