Calcium channel blockers in cirrhotic patients with portal hypertension.

Abstract:

:Four calcium channel blockers, i.e. nifedipine, verapamil, cinnarizine and tetrandrine are currently available and used widely in treating cardiovascular diseases. To confirm the effects, if any, of calcium channel blockers on cirrhotic patients with portal hypertension, a study was performed on esophageal variceal pressure and rebleeding rate of esophageal varices after 2 years by using calcium channel blocker in 321 patients from some 23 hospitals. The results demonstrated that the calcium channel blockers could significantly reduce the esophageal variceal pressure and the portal blood flow in cirrhotic patients with portal hypertension. The proportion of patients with no recurrent gastrointestinal bleeding after 2 years medication of tetrandrine was 87.9% in tetrandrine group, significantly higher than those in the other 4 groups (P < 0.05). It is suggested that tetrandrine should be more effective for cirrhotic patients with portal hypertension in preventing recurrent variceal bleeding.

journal_name

Chin Med J (Engl)

journal_title

Chinese medical journal

authors

Li D,Lu H,Li X,Quan Q,Li X,Lu W

subject

Has Abstract

pub_date

1995-11-01 00:00:00

pages

803-8

issue

11

eissn

0366-6999

issn

2542-5641

journal_volume

108

pub_type

临床试验,杂志文章,随机对照试验
  • The relationship between tumor necrosis factor-alpha gene polymorphisms and acute severe pancreatitis.

    abstract:OBJECTIVE:To investigate the relationship between the presence of the TNF2 allele and plasma concentrations of tumor necrosis factor-alpha (TNF alpha) and soluble TNF receptor (sTNF-R) with the development of acute severe pancreatitis (ASP) and severe sepsis. METHODS:Genomic DNA was prepared from peripheral blood leuk...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Zhang D,Li J,Jiang Z,Yu B,Tang X,Li W

    更新日期:2003-11-01 00:00:00

  • Transcatheter occlusion of multiple aortopulmonary collateral arteries for post-operative heart failure in a patient with tetralogy of Fallot using the Amplatzer vascular plug and a detachable coil.

    abstract::A 10-year-old boy who had previously undergone surgical correction for tetralogy of Fallot was referred for cardiac catheterization because of recurrent symptomatic postoperative heart failure owing to major aortopulmonary collateral arteries (MAPCAs). A successful occlusion of these MAPCAs was achieved percutaneously...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Tang L,Zhou SH

    更新日期:2011-03-01 00:00:00

  • Sutureless choledochoduodenostomy with an intraluminal degradable stent in dog model.

    abstract:BACKGROUND:It is difficult and time-consuming for carrying out conventional hand-sewn bilioenteric anastomosis, especially for small bile duct anastomosis and laparoscopic procedure. In order to simplify it, we have developed a novel procedure of sutureless bilioenteric anastomosis with an intraluminal degradable stent...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Zhu LH,Liang X,Lin H,Wang YF,Zhu YP,Cai XJ

    更新日期:2011-07-05 00:00:00

  • Expression levels and significance of hypoxia inducible factor-1 alpha and vascular endothelial growth factor in human colorectal adenocarcinoma.

    abstract:BACKGROUND:Hypoxia-inducible factor 1 (HIF-1), a transcription factor, is overexpressed in common human cancers and their metastases. This study aimed at determining the expression levels of HIF-1alpha and vascular endothelial growth factor (VEGF) in SW480 cells and in colorectal adenocarcinoma tissue and ascertaining ...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Jiang CQ,Fan LF,Liu ZS,Qian Q,Xia D,Diao LM,He YM,Ai ZL

    更新日期:2004-10-01 00:00:00

  • Temporary arterial occlusion during intracranial aneurysm surgery.

    abstract::Temporary arterial occlusion during intracranial aneurysm surgery is a safe and effective modality. It is not only an emergency measure for controlling aneurysmal bleeding, but also a helpful means for accurate and meticulous dissection and clipping of an intracranial aneurysm with the advantage of minimizing the chan...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Zhou LF,Li SQ,Yang ML

    更新日期:1993-11-01 00:00:00

  • Association and contribution of ERK to IL-6-induced activation of signal transducer and activator of transcription in a human myeloma cell line.

    abstract:OBJECTIVE:To investigate the regulation effect of protein kinase ERK on the activation of transcription factor STAT3 in response to IL-6 in the Sko-007 human myeloma cell line. METHODS:Electrophoretic mobility shift assay (EMSA) and immunoprecipitation (IP) were used to show the activation of STAT3 and ERK in Sko-007 ...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Song L,Shen B,Li Y

    更新日期:2001-09-01 00:00:00

  • Frequency-specific alterations of large-scale functional brain networks in patients with Alzheimer's disease.

    abstract:BACKGROUND:Previous studies have indicated that the cognitive deficits in patients with Alzheimer's disease (AD) may be due to topological deteriorations of the brain network. However, whether the selection of a specific frequency band could impact the topological properties is still not clear. Our hypothesis is that t...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.4103/0366-6999.151654

    authors: Qin YY,Li YP,Zhang S,Xiong Y,Guo LY,Yang SQ,Yao YH,Li W,Zhu WZ

    更新日期:2015-03-05 00:00:00

  • Could Intrathymic Injection of Myelin Basic Protein Suppress Inflammatory Response After Co-culture of T Lymphocytes and BV-2 Microglia Cells?

    abstract:BACKGROUND:The interaction between activated microglia and T lymphocytes can yield abundant pro-inflammatory cytokines. Our previous study proved that thymus immune tolerance could alleviate the inflammatory response. This study aimed to investigate whether intrathymic injection of myelin basic protein (MBP) in mice co...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.4103/0366-6999.178955

    authors: Cui ZQ,Liu BL,Wu QL,Cai Y,Fan WJ,Zhang MC,Ding WL,Zhang B,Kang JM,Yan H

    更新日期:2016-04-05 00:00:00

  • Current status and perspectives of research on radiation hormesis in Japan.

    abstract::The CRIEPI initiated the Radiation Hormesis Research based on the following rationale. If the Luckey's claim was true, our daily activities in the radiation management would be extremely erroneous. If the Luckey's claim was false, the concept publicated would bring us serious disturbance on the radiation management in...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Hattori S

    更新日期:1994-06-01 00:00:00

  • Delayed graft function is correlated with graft loss in recipients of expanded-criteria rather than standard-criteria donor kidneys: a retrospective, multicenter, observation cohort study.

    abstract:BACKGROUND:Although the use of expanded-criteria donors (ECDs) alleviates the problem of organ shortage, it significantly increases the incidence of delayed graft function (DGF). DGF is a common complication after kidney transplantation; however, the effect of DGF on graft loss is uncertain based on the published liter...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.1097/CM9.0000000000000666

    authors: Han F,Lin MZ,Zhou HL,Li H,Sun QP,Huang ZY,Hong LQ,Wang G,Cai RM,Sun QQ

    更新日期:2020-03-05 00:00:00

  • Mitochondrial DNA 4977-bp deletion correlated with reactive oxygen species production and manganese superoxidedismutase expression in gastric tumor cells.

    abstract:BACKGROUND:Mitochondrial DNA 4977-bp deletion (DeltamtDNA(4977)) was reported in many human neoplasia. However, its biological significance remains to be evaluated and the molecular mechanism needs to be investigated. In this study, we analyzed the frequency of DeltamtDNA(4977) in gastric cancer (GC) cell lines and tis...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Wang J,Lü YY

    更新日期:2009-02-20 00:00:00

  • Endothelial progenitor cells with Alzheimer's disease.

    abstract:BACKGROUND:Endothelial dysfunction is thought to be critical events in the pathogenesis of Alzheimer's disease (AD). Endothelial progenitor cells (EPCs) have provided insight into maintaining and repairing endothelial function. To study the relation between EPCs and AD, we explored the number of circulating EPCs in pat...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Kong XD,Zhang Y,Liu L,Sun N,Zhang MY,Zhang JN

    更新日期:2011-03-01 00:00:00

  • Clinical manifestations and immunological features of primary Sjögren's syndrome with liver involvement: analysis of thirty cases.

    abstract:OBJECTIVE:To evaluate the incidence, severity, clinical manifestations and immunological features relevant to liver involvement in 135 cases of primary Sjögren's syndrome. METHODS:One hundred and thirty-five patients with definite primary Sjögren's syndrome were analyzed retrospectively for liver involvement by the ab...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Zhang Z,Dong Y

    更新日期:1998-03-01 00:00:00

  • Novel endoscopic findings as visualized by non-magnification endoscopy with linked color imaging are indicative of gastric intestinal metaplasia.

    abstract:BACKGROUND:Gastric intestinal metaplasia (GIM) is generally considered to be the main mucosal background for the development of gastric adenocarcinomas. Using linked color imaging (LCI), we noticed that the color pattern in areas of GIM was purple mixed with white on the epithelium with signs of mist that were detected...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.1097/CM9.0000000000000172

    authors: Min M,Dong TH,Liu Y,Bi YL,Ma CY

    更新日期:2019-04-05 00:00:00

  • Epidemiology of opportunistic invasive fungal infections in China: review of literature.

    abstract:OBJECTIVE:To summarize the recent findings on the epidemiology of medically important, opportunistic invasive fungal infections (IFIs) in China and discuss the relevant social, economical reasons and medical factors. DATA SOURCES:We performed a comprehensive search of both English and Chinese literatures of opportunis...

    journal_title:Chinese medical journal

    pub_type: 杂志文章,评审

    doi:

    authors: Liao Y,Chen M,Hartmann T,Yang RY,Liao WQ

    更新日期:2013-01-01 00:00:00

  • RANTES In1.1C allele polymorphisms in 13 Chinese ethnic populations.

    abstract:BACKGROUND:The In1.1C single nucleotide polymorphism (SNP) allele results in reduced RANTES transcription, which is associated with increased frequency of HIV-1 infection, and rapid progression to AIDS among HIV-1-infected individuals. This study aimed to study the mutant frequency and polymorphism of RANTES in Chinese...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Qian Y,Sun H,Chu JY

    更新日期:2009-05-20 00:00:00

  • Effect of recombinant adenovirus vector mediated human interleukin-24 gene transfection on pancreatic carcinoma growth.

    abstract:BACKGROUND:Pancreatic cancer is a highly malignant tumor affecting an ever increasing number of patients with a mean 5-year survival rate below 4%. Therefore, gene therapy for cancer has become a potential novel therapeutic modality. In this study we sought to determine the inhibitory effects of adenovirus-mediated hum...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Pan XT,Zhu QY,Li DC,Yang JC,Zhang ZX,Zhu XG,Zhao H

    更新日期:2008-10-20 00:00:00

  • Oviduct occlusion by intraluminal thread and silver clips.

    abstract::100 women ranging in age from 26-34 years were followed up for 4-21 months after undergoing sterilization by tubal occlusion using intraluminal threads and silver clips. The number of children/woman ranged from 1-5 with 80% having 2. 31 women underwent sterilization postmenstrually, 11 midmenstrually, 28 premenstrua...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Ding SL

    更新日期:1983-08-01 00:00:00

  • Morphological evidence of telocytes in mice aorta.

    abstract:BACKGROUND:Telocytes (TCs) are a novel type of interstitial cells, which have been recently described in a large variety of cavitary and noncavitary organs. TCs have small cell bodies, and remarkably thin, long, and moniliform prolongations called telopodes (Tps). Until now, TCs have been found in various loose connect...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.4103/0366-6999.150102

    authors: Zhang HQ,Lu SS,Xu T,Feng YL,Li H,Ge JB

    更新日期:2015-02-05 00:00:00

  • Magnetic resonance imaging of the extraocular muscles and corresponding cranial nerves in patients with special forms of strabismus.

    abstract:BACKGROUND:With the technical advances, magnetic resonance imaging (MRI) is now sensitive enough to detect subtle structural abnormalities of ocular motor nerves arising from the brainstem and orbits of living subjects. This study was designed to delineate the MRI characteristics in patients with special forms of strab...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Jiao YH,Zhao KX,Wang ZC,Qian XH,Wu X,Man FY,Lu W,She HC

    更新日期:2009-12-20 00:00:00

  • Relief of abdominal pain by morphine without altering physical signs in acute appendicitis.

    abstract:BACKGROUND:Abdominal pain is a common symptom among patients with acute appendicitis, yet these patients have long been denied relief from suffering because of widespread misconceptions associated with the use of opioids. We determined whether morphine hydrochloride masked the physical signs in adults with acute append...

    journal_title:Chinese medical journal

    pub_type: 杂志文章,随机对照试验

    doi:

    authors: Yuan Y,Chen JY,Guo H,Zhang Y,Liang DM,Zhou D,Zhao H,Lin F

    更新日期:2010-01-20 00:00:00

  • Endolymphatic sac papillary tumor: a case report.

    abstract::Endolymphatic sac papillary tumor (ELST) is an extremely rare and aggressive tumor characterized by hearing loss and temporal bone destruction. A case with clinical, imaging, pathologic and treatment data is reported and relevant literature is reviewed. A 25-year-old woman, with ELST underwent craniotomy for tumor sub...

    journal_title:Chinese medical journal

    pub_type: 杂志文章,评审

    doi:

    authors: Yu SJ,Chen YD,Gao F,Qiu XG,Chang H

    更新日期:2011-11-01 00:00:00

  • Multi personal computer storage system: solution of sea capacity PACS storage.

    abstract:OBJECTIVE:According to the characteristics of digital medicine and the demands of digitalized management in hospitals, we established a storage system that is affordable, highly expandable, and reliable. METHODS:The multi personal computer storage system (MPCSS) was constructed using hardware and software. The image d...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Guo Q,Hao F,Duan X,Xie X,Liao W

    更新日期:2003-05-01 00:00:00

  • Clinical significance of elevated serum soluble interleukin-2 receptor in gastric cancer.

    abstract::This is China's pilot study in the assessment of the diagnostic value of serum soluble IL-2 receptor (sIL-2R) in gastric cancer. We measured its level by ELISA method in 45 patients with gastric cancer (without metastasis: 32; with metastasis: 5; recurrence: 8) 27 gastric ulcer, 27 superficial gastritis and 44 healthy...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Wang YF,Wu XN,Zhou YH,Chen XF,Shen J,Wang HJ

    更新日期:1994-04-01 00:00:00

  • A bicistronic retroviral vector to introduce drug resistance genes into human umbilical cord blood CD34+ cells to improve combination chemotherapy tolerance.

    abstract:OBJECTIVE:To study whether human umbilical cord blood CD34+ cells transduced with human aldehyde dehydrogenase class-1 (ALDH-1) and multidrug resistance gene (MDR1) have increases resistance to 4-Hydroperoxycyclo-phosphamide (4-HC) and P-glycoprotein effluxed drugs. METHODS:A bicistronic retroviral vector G1Na-ALDH1-I...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Wang J,Chen Z,Xia X,Lu D,Xue J,Ruan C

    更新日期:2001-01-01 00:00:00

  • Increased RhoGDI2 and peroxiredoxin 5 levels in asthmatic murine model of beta2-adrenoceptor desensitization: a proteomics approach.

    abstract:BACKGROUND:Beta(2)-adrenoceptor (beta(2)AR) desensitization is a common problem in clinical practice. beta(2)AR desensitization proceeds by at least such three mechanisms as heterologous desensitization, homologous desensitization and a kind of agonist-induced rapid phosphorylation by a variety of serine/threonine kina...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Liu H,Zhou LF,Zhang Q,Qian FH,Yin KS,Huang M,Zhang XL

    更新日期:2008-02-20 00:00:00

  • Safety and immunogenicity of lyophilized, live attenuated hepatitis A vaccine in non-human primate model.

    abstract:OBJECTIVE:To evaluate the safety and immunogenicity of lyophilized, live attenuated hepatitis A vaccine (H2 strain) in rhesus monkeys. METHODS:Nine adult rhesus monkeys were used as experimental animals. The rhesus monkeys without anti-HAV were divided randomly into the aqueous vaccination group (4 rhesus monkeys), th...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Hu Y,Tan S,Shao C,Jin W,Ji Q,He J,Chen H,Yan J

    更新日期:2000-04-01 00:00:00

  • Factors as predictors for thoracic and thoracolumbar/lumbar structural curves in adolescent idiopathic scoliosis.

    abstract:BACKGROUND:Recent studies have demonstrated that the Lenke system is relatively efficient and consistent in classifying scoliosis curves. Basically, fusion should include the main curve and the structural minor curve. The criteria for defining the structural minor curve were established to help guide these decision-mak...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Chen ZQ,Zhao YF,He SS,Wang CF,Zhang JT,Zhao YC,Yang CW,Li M

    更新日期:2012-04-01 00:00:00

  • Induction of islet transplantation tolerance with anti-CD4, anti-CD8 immunotoxins and donor soluble antigen.

    abstract:OBJECTIVE:To induce islet grafting tolerance by intravenous injection of anti-CD4, anti-CD8 immunotoxins and donor soluble antigen. METHODS:Fourteen days or 7 days prior to transplantation, the immunotoxin of anti-CD4, anti-CD8 200 micrograms respectively, and donor soluble antigen 500 micrograms were intravenously in...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Lan P,Yan L,Xiao L

    更新日期:1999-12-01 00:00:00

  • Angiographic prevalence of myocardial bridging in a defined very large number of Chinese patients with chest pain.

    abstract:BACKGROUND:Muscle fibers overlying the intramyocardial segment of an epicardial coronary artery are termed myocardial bridging (MB). Variable prevalence of MB has been described at autopsy and angiographic series with small and large sample size studies. In addition, no similar study was reported in Chinese population....

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Li JJ,Shang ZL,Yao M,Li J,Yang YJ,Chen JL,Qiao SB,Ma WH,Qin XW,Liu HB,Wu YJ,Yuan JQ,Chen J,You SJ,Dai J,Xu B,Xia R,Gao RL

    更新日期:2008-03-05 00:00:00