Identification of seven novel mutations in the factor VIII gene in 18 unrelated Chinese patients with hemophilia A.

abstract：BACKGROUND:A simple, safe and effective therapeutic strategy for traumatic instability of the subaxial cervical spine, as well as its prognostic assessment, is still controversial. METHODS:The therapeutic options for 83 patients of traumatic instability of the subaxial cervical spine, whose average age was 35 years, w...

journal_title：Chinese medical journal

authors： Cao P,Liang Y,Gong YC,Zheng T,Zhang XK,Wu WJ

更新日期：2008-08-05 00:00:00

abstract：BACKGROUND:Both cortical and cortical-subcortical (cortex-involved) lesions are typically associated with embolic stroke, of which atrial fibrillation (AF) is the common cause. The aim of this study was to find out the associations between cortex-involved stroke, vascular risk factors, and the subtypes (discovery time ...

journal_title：Chinese medical journal

authors： Li SY,Yang XM,Zhao XQ,Liu LP,Wang YL,Jiang Y,Wang YJ

更新日期：2019-09-05 00:00:00

abstract：OBJECTIVE:Little information is available to guide treatment strategies regarding patients with unexpected positive cultures (UPC), including Propionibacterium acnes (PA), without overt signs of infection in revision shoulder arthroplasty (RSA). The purpose of our study was to analyze the prevalence, clinical meaning, ...

journal_title：Chinese medical journal

authors： Kim SJ,Kim JH

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To identify novel tumor suppressor genes at chromosome 3p24-26 in human nasopharyngeal carcinoma (NPC). METHODS:Twenty epithelial-derived expressed sequence tags (EST) were selected from chromosome 3p24-26. RT-PCR and Northern blot were used to detect the expression of the ESTs in NPC cell line, HNE-1, and p...

journal_title：Chinese medical journal

authors： Xie Y,Bin L,Yang J,Li Z,Yu Y,Zhang X,Cao L,Li G

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:Beta(2)-adrenoceptor (beta(2)AR) desensitization is a common problem in clinical practice. beta(2)AR desensitization proceeds by at least such three mechanisms as heterologous desensitization, homologous desensitization and a kind of agonist-induced rapid phosphorylation by a variety of serine/threonine kina...

journal_title：Chinese medical journal

authors： Liu H,Zhou LF,Zhang Q,Qian FH,Yin KS,Huang M,Zhang XL

更新日期：2008-02-20 00:00:00

abstract：BACKGROUND:Severe valgus deformity often has bone defect and laxity of the medial ligamentous, and total knee arthroplasty in severe valgus knee is, in most cases, more challenging for surgeons. The usefulness of a computer assisted navigation system in reestablishing the mechanical axis has been well established. Henc...

journal_title：Chinese medical journal

authors： Shao JJ,Zhang XL,Wang Q,Chen YS,Shen H,Jiang Y

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to demonstrate the lumbar pedicle cortical bone trajectory (CBT) screw fixation technique, a new fixation technique for lumbar surgery. DATA SOURCES:The data analyzed in this review are mainly from articles reported in PubMed published from 1994 to 2014. STUDY SELECTION:Origina...

journal_title：Chinese medical journal

authors： Song T,Hsu WK,Ye T

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Diffusion weighted imaging with background suppression (DWIBS) is potentially useful in detecting metastatic lymph nodes. This study aimed to evaluate the efficacy of DWIBS at 3T magnetic resonance (MR) for diagnosing metastatic lymph nodes in cervical cancer. METHODS:This retrospective study included 25 pa...

journal_title：Chinese medical journal

authors： Yu SP,He L,Liu B,Zhuang XZ,Liu MJ,Hu XS

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:It has been widely demonstrated that endothelial progenitor cells are involved in several diseases and that they have therapeutic implications. In order to define the altered pulmonary vascular homeostasis in chronic obstructive pulmonary disease, we sought to observe the level and functions of circulating e...

journal_title：Chinese medical journal

authors： Yang Y,Gan Y,Cao J,Chen Y,He ZH,Luo H,Cai S,Xiang XD,Zhou R,Chen P

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of Q-switched alexandrite laser irradiation on dermal melanocytes of nevus of Ota. METHODS:Multiple biopsies were carried out on 4 patients with nevus of Ota before and after laser irradiation. Altogether 11 samples were examined under light microscope and 14 under transmission elec...

journal_title：Chinese medical journal

authors： Lu Z,Chen J,Wang X,Fang L,Jiao S,Huang W

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Four single nucleotide polymorphisms (SNPs) in the modulator recognition factor 2/AT-rich interaction domain 5B (MRF2/ARID5B) gene located at chromosome 10q21.2 have been shown to be associated with both type 2 diabetes mellitus (T2DM) and coronary artery disease in a Japanese cohort. This study aimed to inv...

journal_title：Chinese medical journal

authors： Sun LL,Zhang SJ,Chen MJ,Elena K,Qiao H

更新日期：2017-05-05 00:00:00

abstract：BACKGROUND:Bone grafting is commonly used to repair bone defects. As the porosity of the graft scaffold increases, bone formation increases, but the strength decreases. Early attempts to engineer materials were not able to resolve this problem. In recent years, nanomaterials have demonstrated the unique ability to impr...

journal_title：Chinese medical journal

authors： Tang D,Xu G,Yang Z,Holz J,Ye X,Cai S,Yuan W,Wang Y

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Proteasome subunits (PSMB) and transporter associated with antigen processing (TAP) loci are located in the human leukocyte antigen (HLA) Class II region play important roles in immune response and protein degradation in neurodegenerative diseases. This study aimed to explore the association between single n...

journal_title：Chinese medical journal

authors： Mo MS,Huang W,Sun CC,Zhang LM,Cen L,Xiao YS,Li GF,Yang XL,Qu SG,Xu PY

更新日期：2016-05-05 00:00:00

abstract：BACKGROUND:Fluid dynamic mechanisms attributed to coronary bifurcation lesions remain a subject of study. The present study aimed at investigating the hemodynamic change of wall shear stress (WSS) in patients with coronary bifurcation lesions treated by double kissing (DK) crush or one-stent with final kissing balloon ...

journal_title：Chinese medical journal

authors： Chen SL,Kan J,Zhang JJ,Hu ZY,Xu T

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Ovarian serous adenocarcinoma can be divided into low- and high-grade tumors, which exhibit substantial differences in pathogenesis, clinicopathology, and prognosis. This study aimed to investigate the differences in the PH domain leucine-rich repeat protein phosphatase (PHLPP), forkhead homeobox type O 3a (...

journal_title：Chinese medical journal

authors： Zhang J,Wang JC,Li YH,Wang RX,Fan XM

更新日期：2017-02-05 00:00:00

abstract：OBJECTIVE:To study the clinicopathologic features and immunoprofile of angiomyofibroblastoma (AMF) with emphasis on differential diagnosis. METHODS:Seven vulvar, two vaginal and one perineal angiomyofibroblastomas were evaluated by light microscopy and immunohistochemistry. The immunohistochemical studies were perform...

journal_title：Chinese medical journal

authors： Wang J,Sheng W,Tu X,Shi D,Zhu X,Zhang R

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:Orthotopic liver transplantation (OLT) has become the therapeutic option of choice for end-stage liver disease. The aim of this study was to investigate the changes of splenic morphology, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), apparent diffusion coefficient (ADC) values and explore their...

journal_title：Chinese medical journal

authors： Wang J,Liang Y,Yan R,Jiang Z,Liu J,Hu B,He B,Ren L,Chen J,Shan H

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Porcine liver performing efficient physiological functions in the human body is prerequisite for successful liver xenotransplantation. However, the protein differences between pig and human remain largely unexplored. Therefore, we investigated the liver expression profile of a highly inbred minipig line. ME...

journal_title：Chinese medical journal

authors： Chen YN,Tan WD,Lu YR,Qin SF,Li SF,Zeng YZ,Bu H,Li YP,Cheng JQ

更新日期：2007-05-05 00:00:00

abstract：BACKGROUND:HIV-1 infected and immune-activated macrophages and microglia secrete neurotoxins, such as tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β), which play major role in the neuronal death. It has been shown that different HIV-1 variants have varying abilities to elicit secretion of TNF-α by peripheral...

journal_title：Chinese medical journal

authors： Yan YF,Wang ZY,Pu SS,Wen HL,Huang T,Song YY,Xu HZ,Zhao L

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:There are relatively few reports focusing on clinical and multi-slice CT (MSCT) imaging findings of mucinous tubular and spindle cell carcinoma (MTSCC). Our study aimed to characterize the clinical and MSCT imaging features of MTSCC. METHODS:The imaging findings in 17 patients with MTSCC by MSCT were retros...

journal_title：Chinese medical journal

authors： Zhu Q,Zhu W,Wang Z,Wu J

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To study the experience in the treatment of subclavian steal syndrome (SSS) and the relation between SSS and the damage of brain. METHODS:In 28 patients with SSS, 23 were operated on. They complained of vertigo, TIA, and claudication of arms. One patient suffered from severe stem ischemia spasm. All the pati...

journal_title：Chinese medical journal

authors： Guan H,Liu C,Yu Z

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND:The best age for the arterial switch operation (ASO) in complete transposition of great arteries with ventricular septal defect is usually considered to be within six months. This is because of severe pulmonary arterial hypertension and pulmonary arterial obstructive pathological changes. There are few repor...

journal_title：Chinese medical journal

authors： Liu CH,Su JW,Li ZQ,Fan XM,Chen Y,He Y,Liu YL

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:One stage transanal Soave pull-through procedure (TSPP) is a recent popular operation in the treatment of Hirschsprung's disease (HD). With no visible scar and a short hospital stay, it is well accepted by surgeons and mothers. In the conventional Soave procedure, a long rectal muscular cuff left for anocoli...

journal_title：Chinese medical journal

authors： Li AW,Zhang WT,Li FH,Cui XH,Duan XS

更新日期：2006-01-05 00:00:00

abstract：BACKGROUND:Previous studies have demonstrated increased functions of osteoblasts on nanophase materials compared to conventional ceramics or composites. Nanophase materials are unique materials that simulate dimensions of constituent components of bone as they possess particle or grain sizes less than 100 nm. However, ...

journal_title：Chinese medical journal

authors： Han P,Ji WP,Zhao CL,Zhang XN,Jiang Y

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:C-arm-based flat-panel detector cone-beam computed tomography (CBCT) venography has never been used in the management of iliac vein compression syndrome (IVCS). This study aimed to determine the technical feasibility and safety of CBCT venography in the diagnosis of IVCS compared with conventional venography...

journal_title：Chinese medical journal

authors： Wang CM,Zhang WL,Li X

更新日期：2020-08-26 00:00:00

abstract：BACKGROUND:In 2012, the working group on abdominal problems of the European Society of Intensive Care Medicine (ESICM) proposed a definition and also guidelines for the grading system and treatment of acute gastrointestinal injury (AGI). Until now, clinical reports on this topic have not been available, and the practic...

journal_title：Chinese medical journal

authors： Zhang D,Li N,Dong L,Fu Y,Liu Z,Wang Y

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To report the surgical techniques and results of an 8-year follow-up study of 42 patients with a modified orthotopic ileal neobladder restoring normal anatomical relationship. METHODS:Total cystoprostatectomy was performed extraperitoneally. A 45 - 50 cm segment of the ileal loop was isolated, detubularized,...

journal_title：Chinese medical journal

authors： Huang J,Xu K,Yao Y,Guo Z,Lin T,Jiang C

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND:Primary percutaneous coronary intervention (PCI) has been identified as the first therapeutic option for patients with acute ST-segment elevation myocardial infarction (STEMI). The strategy of transferring patient to a PCI center was recently recommended for those with acute STEMI who were present to PCI inc...

journal_title：Chinese medical journal

authors： Zhang Q,Zhang RY,Qiu JP,Zhang JF,Wang XL,Jiang L,Liao ML,Zhang JS,Hu J,Yang ZK,Shen WF

更新日期：2008-03-20 00:00:00

abstract：BACKGROUND:Pancreatic cancer is a highly malignant tumor affecting an ever increasing number of patients with a mean 5-year survival rate below 4%. Therefore, gene therapy for cancer has become a potential novel therapeutic modality. In this study we sought to determine the inhibitory effects of adenovirus-mediated hum...

journal_title：Chinese medical journal

authors： Pan XT,Zhu QY,Li DC,Yang JC,Zhang ZX,Zhu XG,Zhao H

更新日期：2008-10-20 00:00:00

abstract：BACKGROUND:Gastric intestinal metaplasia (GIM) is generally considered to be the main mucosal background for the development of gastric adenocarcinomas. Using linked color imaging (LCI), we noticed that the color pattern in areas of GIM was purple mixed with white on the epithelium with signs of mist that were detected...

journal_title：Chinese medical journal

authors： Min M,Dong TH,Liu Y,Bi YL,Ma CY

更新日期：2019-04-05 00:00:00