Association Analysis of Proteasome Subunits and Transporter Associated with Antigen Processing on Chinese Patients with Parkinson's Disease.

abstract：BACKGROUND:Whether an addition of OAC to double antiplatelet therapy for patients with an indication of chronic oral anticoagulation undergoing PCI-S may improve clinical outcomes is still debated. This meta-analysis aimed to update and re-compare the benefits and risks of triple antithrombotic therapy (TT) with double...

journal_title：Chinese medical journal

authors： Saheb KJ,Deng BQ,Hu QS,Xie SL,Geng DF,Nie RQ

更新日期：2013-07-01 00:00:00

abstract：:Three cases with disseminated Penicilliosis marneffei (PSM) are reported. They are all natives of Guangxi Zhuang Autonomous Region. Among them, 2 died and 1 remains alive. Their clinical features were characterized by multiple organ involvement, multiple subcutaneous abscesses, inflammatory papules, nodules and pustul...

journal_title：Chinese medical journal

authors： Li JS,Pan LQ,Wu SX,Su SX,Su SB,Shan LY

更新日期：1991-03-01 00:00:00

abstract：OBJECTIVE:To investigate the incidence rate, pathologic changes, mechanisms and diagnostic methods in renal bone disease. METHODS:The blood levels of carboxyterminal parpthyriod hormone (C-PTH), 1,25(OH)2D3, calcium and phosphate, aluminum in serum and bone tissue were measured. The bone biopsy and bone scan with 99m ...

journal_title：Chinese medical journal

authors： Zhu P,Wang G,Yu Y,Lou D,Wang S,Jia J,Dong D

更新日期：1998-09-01 00:00:00

abstract：:An ovarian gynandroblastoma was found in a 59-year-old woman. The tumor consisting of mixed Sertoli-Leydig cells and granulosa-theca cells demonstrated no malignant features. Bisexual cells in gynandroblastoma derived from a common gonadal mesenchyme precursor or indifferent cell. The excision of appendages with tumor...

journal_title：Chinese medical journal

authors： Zhang SQ

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Chronic hepatic inflammation is characterized by the accumulation of lymphocytes as a consequence of increased recruitment from the blood and retention within the tissue at sites of infection. CXC chemokine ligand 16 (CXCL16) mRNA has been detected in both inflamed and normal liver tissues and is strongly up...

journal_title：Chinese medical journal

authors： Wang P,Kan QC,Yu ZJ,Li L,Pan X

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:The hyperdynamic circulatory state in end-stage liver disease is similar to the hemodynamic state in endotoxic shock. Recent research indicated that proper use of norepinephrine (NE) in patients with endotoxic shock could improve the perfusion of visceral organs and raise the survival rate. In this study, do...

journal_title：Chinese medical journal

authors： Zhang LP,Li M,Yang L

更新日期：2005-12-05 00:00:00

abstract：BACKGROUND:It is important to determine prognostic factors for the outcome of amyotrophic lateral sclerosis (ALS) at an early stage. The time taken for symptoms to spread from spinal or bulbar regions to both (time to generalization; TTG) is considered a strong predictor of survival; however, this has rarely been studi...

journal_title：Chinese medical journal

authors： Sun QH,Li YR,Lan WJ,Yang F,Cui F,Huang XS

更新日期：2019-05-05 00:00:00

abstract：OBJECTIVE:To investigate the use of the Gibbs-Sampler method in evaluating the relationship between clinic events and health risks in a meta-analysis of multiple clinical trials. METHODS:By using a generalized linear model with random-effects, Gibbs-Sampler technique was used in a meta-analysis of multiple clinical tr...

journal_title：Chinese medical journal

authors： Wang Y,Wang Y,Li L,Wang Z,Macus F,Salim Y

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:The columella, nasal tip, lip relationship in the bilateral cleft lip nasal deformity remains a great challenge for plastic surgeon. An esthetically satisfying result is difficult to obtain. A subset of patients with bilateral cleft lip nasal deformity still require columellar lengthening and nasal correctio...

journal_title：Chinese medical journal

authors： Yan W,Zhao ZM,Yin NB,Song T,Li HD,Wu D,Gao F,Wang XG

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Thoracic endovascular aortic repair (TEVAR) is an emerging treatment modality, which has been rapidly embraced by clinicians treating thoracic aortic disease. However, the clinical manifestations of systemic inflammatory response after TEVAR as post-implantation syndrome (PIS) resemble the perioperative infe...

journal_title：Chinese medical journal

authors： Xue L,Luo S,Luo J,Liu Z,Gu M,Kang H,Yang F,Nie B,Liu Y,Huang W,Xie N,He P,Dong H,Ni Z,Fan R,Chen J

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To explore the response of nasal mucosa epithelial cells to hypoxia in terms of formation of nasal polyps (NP). METHODS:Epithelial cells of NP and inferior turbinate (IT) were cultured serum-free under normal oxygen and hypoxic circumstances with stimulation of IL-1 beta and TNF alpha. The vascular endotheli...

journal_title：Chinese medical journal

authors： Jiang S,Dong Z,Zhu D,Yang Z

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:Estrogen deficiency causes atrophic changes within the urogenital tract, and is associated with urinary symptoms. The purpose of this study was to investigate the effects of estrogen and tibolone on bladder histology, and the changes of estrogen receptor alpha and beta (ERalpha and beta) protein expression i...

journal_title：Chinese medical journal

authors： Yang X,Li YZ,Mao Z,Gu P,Shang M

更新日期：2009-02-20 00:00:00

abstract：BACKGROUND:Allergic rhinitis (AR) is a Th2 dominant cytokine response. Chloride channel-3 (ClC-3) plays an important role in nasal mucosal edema and inflammatory pathologic changes in AR. Antiallergic herbal agents (AHA) are antiallergic herbal products. In the previous study, we have demonstrated that AHA clearly inhi...

journal_title：Chinese medical journal

authors： Wang LF,Xu LJ,Guo FH,Wang LN,Shen XH

更新日期：2010-04-20 00:00:00

abstract：BACKGROUND:This study was designed to evaluate the relationship between high-density lipoprotein cholesterol (HDL-C) level and acute myocardial infarction (AMI) and coronary heart disease (CHD) death and to explore the protective effect of HDL against CHD in the elderly Chinese. METHODS:Started from 1986, 1211 retiree...

journal_title：Chinese medical journal

authors： Li JZ,Chen ML,Wang S,Dong J,Zeng P,Hou LW

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:The CYP2C19 G681A single polymorphism has been proven to affect clopidogrel responsiveness. However, the effect of coexisting polymorphisms of other genes has not yet been reported in the Chinese population. This study investigated the effect of coexisting polymorphisms of CYP2C19 and P2Y12 on clopidogrel re...

journal_title：Chinese medical journal

authors： Tang XF,Zhang JH,Wang J,Han YL,Xu B,Qiao SB,Wu YJ,Chen J,Wu Y,Chen JL,Gao RL,Yang YJ,Yuan JQ

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVE:To detect occult metastases in lymph nodes from patients with colorectal carcinoma and its clinical significance. METHODS:The metastases in 260 lymph nodes from 39 histologically verified colorectal cancer patients were studied by both hematoxylin-eosin (HE) staining and cytokeratin-20 (CK20) specific RT-PCR...

journal_title：Chinese medical journal

authors： Liu Z,Ye X,Bi W,Wang M,Li Y,Chen T

更新日期：2002-04-01 00:00:00

abstract：OBJECTIVE:To identify new recombinant antigens with potential for diagnosis of hemorrhagic fever with renal syndrome (HFRS) and establish reverse transcription-polymerase chain reaction-restriction fragments length polymorphism (RT-PCR-RFLP) for genotyping of hantavirus. METHODS:One group of primers was used to clone ...

journal_title：Chinese medical journal

authors： Tang J,Cao M,Tang T,Wang C,Wei C,Lei W

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:Immune cells within a tumor microenvironment have shown modulatory effects on tumor angiogenic activity. Renal cell carcinoma (RCC) is a hypervascular tumor that reportedly increases the frequency of regulatory T cells (Tregs) in tumor tissues. This study investigated the correlation between Tregs infiltrati...

journal_title：Chinese medical journal

authors： Ning H,Shao QQ,Ding KJ,Gao DX,Lu QL,Cao QW,Niu ZH,Fu Q,Zhang CH,Qu X,Lü JJ

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:With the technical advances, magnetic resonance imaging (MRI) is now sensitive enough to detect subtle structural abnormalities of ocular motor nerves arising from the brainstem and orbits of living subjects. This study was designed to delineate the MRI characteristics in patients with special forms of strab...

journal_title：Chinese medical journal

authors： Jiao YH,Zhao KX,Wang ZC,Qian XH,Wu X,Man FY,Lu W,She HC

更新日期：2009-12-20 00:00:00

abstract：OBJECTIVE:To investigate an method for hepatic differentiation from embryonic stem cells (ES cells) in vitro and the resulting differentiation ratio, in order to develop a procedure for producing a new type of hepatocyte for hepatocyte replacement therapy in the treatment of liver failure. METHODS:ES cells from Balb/C...

journal_title：Chinese medical journal

authors： Hu A,Cai J,Zheng Q,He X,Pan Y,Li L

更新日期：2003-12-01 00:00:00

abstract：OBJECTIVE:To investigate the efficacy of continuous renal replacement therapy (CRRT) versus intermittent hemodialysis (IHD) in patients with severe acute renal failure (ARF). METHODS:One hundred and ninety-three severe ARF patients who received renal support between December 1978 and December 1998 were involved in thi...

journal_title：Chinese medical journal

authors： Ji D,Gong D,Xie H,Xu B,Liu Y,Li L

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:The long-term safety and efficacy of drug-eluting stents (DES) versus bare metal stents (BMS) are unclear and controversial issues in patients with acute ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI). The purpose of this study was to compare the long-t...

journal_title：Chinese medical journal

authors： Wang CH,Fang Q,Zhang SY,Shen ZJ,Fan ZJ,Jin XF,Zeng Y,Liu ZY,Xie HZ,Yang M

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Previous studies have showed that photooxidative stress can lead to down-modulation of nuclear factor-kappa B (NF-kappaB) activity causing apoptosis of cultured photoreceptor cells. This study aimed at investigating whether NF-kappaB was involved in photoreceptor cells apoptosis induced by N-methyl-N-nitroso...

journal_title：Chinese medical journal

authors： Yang JN,Luo L,Lin SC,Chen JM,Li D,Hu SX

更新日期：2005-07-05 00:00:00

abstract：:The effects of anisodamine on acetylcholine-induced endothelium-dependent relaxation were studied in organ chambers and under bioassay conditions. In organ chamber experiments, both acetylcholine and bradykinin induced an endothelium-dependent relaxation of norepinephrine-contracted canine femoral arteries in a concen...

journal_title：Chinese medical journal

authors： Guo HY,Loren RR,Vanhutte PM

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND:Effects of icariin on airway inflammation in asthmatic rats and the intervention of LPS induced inflammation are interfered with the machanism of icariin. Our study aimed to observe the effect of icariin on ovalbumin-induced imbalance of Th1/Th2 cytokine expression and its mechanism. METHODS:Sixty male SD r...

journal_title：Chinese medical journal

authors： Xu CQ,LE JJ,Duan XH,DU WJ,Liu BJ,Wu JF,Cao YX,Dong JC

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVE:The objective was to provide a brief history of J wave syndromes and to summarize our current understanding of their molecular, ionic, cellular mechanisms, and clinical features. We will also discuss the existing debates and further direction in basic and clinical research for J wave syndromes. DATA SOURCES:...

journal_title：Chinese medical journal

authors： Li GL,Yang L,Cui CC,Sun CF,Yan GX

更新日期：2015-04-05 00:00:00

abstract：BACKGROUND:Intensive treatment such as autologous peripheral blood stem cell (PBSC) transplantation is an important therapeutic strategy in many hematologic malignancies. A number of factors have been reported to impact PBSC mobilization, but the predictive factors varied from one study to another. This retrospective s...

journal_title：Chinese medical journal

authors： Yang SM,Chen H,Chen YH,Zhu HH,Zhao T,Liu KY

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:O(6)-methylguanine-DNA-methyltransferase (MGMT) is a specific DNA revising enzyme transferring alkylated groups from DNA to its cysteine residue to avoid the abnormal twisting of DNA. Therefore, it is one of the drug resistant genes targeted in the treatment of cancer. This study explored the protective effe...

journal_title：Chinese medical journal

authors： Li DB,Wang JS,Fang Q,Sun HY,Xu W,Li WD

更新日期：2007-04-20 00:00:00

abstract：BACKGROUND:The coordinated change of haematopoietic supporting microenvironment in bone marrow (BM) is crucial for innate immunity and inflammation. As the precursors of marrow stroma, BM derived mesenchymal stem cells (MSCs) promote haematopoietic function, but their roles in innate immunity or inflammation have not b...

journal_title：Chinese medical journal

authors： Shi L,Wang JS,Liu XM,Hu XY,Fang Q

更新日期：2007-10-05 00:00:00

abstract：BACKGROUND:Chronic obstructive pulmonary disease (COPD) is thought to be an inflammatory immune response disease. In most cases, the disease is caused by cigarette smoke, but it has been demonstrated that only 10% to 20% of smokers will definitely suffer from COPD. Dendritic cells (DCs) are considered to be the promote...

journal_title：Chinese medical journal

authors： Su YW,Xu YJ,Liu XS

更新日期：2010-06-01 00:00:00