Five-year follow-up of immune response to hepatitis B vaccine in juveniles.

abstract：BACKGROUND:Respiratory syncytial virus (RSV) is a common pathogen in the lower respiratory tract of infants and children. Recent studies have shown that in adults, especially in the elderly population who have relatively weak immunity, lower respiratory tract infection is not uncommon. RSV was detected in 22% hospitali...

journal_title：Chinese medical journal

authors： Li W,Shen HH

更新日期：2007-01-05 00:00:00

abstract：BACKGROUND:Smoking and body mass index (BMI) are the key risk factors for chronic obstructive pulmonary disease (COPD). Adiponectin with both anti-inflammatory and pro-inflammatory properties is a vital modulator of inflammatory processes, which is expressed in epithelial cells in the airway in COPD-emphysema. The aim ...

journal_title：Chinese medical journal

authors： Wang RY,Liu H,Ma LJ,Xu JY

更新日期：2016-01-20 00:00:00

abstract：BACKGROUND:Recent studies have suggested that p38 mitogen-activated protein kinases (MAPK) signalling pathway plays an important role in hepatic fibrosis. This study explored the antifibrotic effect of oxymatrine on tetrachloromethane induced liver fibrosis in rats and its modulation on the p38 MAPK signalling pathway....

journal_title：Chinese medical journal

authors： Deng ZY,Li J,Jin Y,Chen XL,Lü XW

更新日期：2009-06-20 00:00:00

abstract：BACKGROUND:Effects of icariin on airway inflammation in asthmatic rats and the intervention of LPS induced inflammation are interfered with the machanism of icariin. Our study aimed to observe the effect of icariin on ovalbumin-induced imbalance of Th1/Th2 cytokine expression and its mechanism. METHODS:Sixty male SD r...

journal_title：Chinese medical journal

authors： Xu CQ,LE JJ,Duan XH,DU WJ,Liu BJ,Wu JF,Cao YX,Dong JC

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVE:To investigate the role of AC-cAMP system in the transmission of the action of the growth hormone releasing hormone (GRH) on growth hormone (GH) release in pituitary GH-secreting adenomas. METHODS:The effects of GRH (10(-7) mol/L) on intracellular cAMP levels and GH release and the effects of AC-cAMP stimula...

journal_title：Chinese medical journal

authors： Shi Y,Deng J,Yin J

更新日期：1996-08-01 00:00:00

abstract：BACKGROUND:Orthotopic liver transplantation (OLT) has become the therapeutic option of choice for end-stage liver disease. The aim of this study was to investigate the changes of splenic morphology, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), apparent diffusion coefficient (ADC) values and explore their...

journal_title：Chinese medical journal

authors： Wang J,Liang Y,Yan R,Jiang Z,Liu J,Hu B,He B,Ren L,Chen J,Shan H

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To investigate the feasibility of adrenal sparing surgery for selected renal cell carcinoma (RCC), since the necessity of routine adrenalectomy during radical nephrectomy for RCC has been challenged in recent years. METHODS:178 patients underwent perifascial nephrectomy in a 16-year period. Of these patients...

journal_title：Chinese medical journal

authors： Xu C,Niu Z,Lü J,Wang J

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND:An inflammatory response leading to organ dysfunction and failure continues to be a major problem after injury in many clinical conditions such as sepsis, severe burns, and trauma. It is increasingly recognized that atrial natriuretic peptide (ANP) possesses a broad range of biological activities, including ...

journal_title：Chinese medical journal

authors： Zhu YB,Zhang YB,Liu DH,Li XF,Liu AJ,Fan XM,Qiao CH,Ling F,Liu YL

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Glaucoma is mainly characterized by the loss of retinal ganglion cells. Ciliary neurotrophic factor (CNTF) is believed to stimulate the regeneration of axons of retinal ganglion cells. The objective of our study was to detect the expression of CNTF in the retina of a rat glaucoma model with increased intraoc...

journal_title：Chinese medical journal

authors： Wu Q,Zhang M,Song BW,Lu B,Hu P

更新日期：2007-10-20 00:00:00

abstract：OBJECTIVE:To investigate CTLA4-Ig's potential role in therapy for allergic asthma by blocking B7/CD28 interactions with cytotoxic T lymphocyte antigen 4-Ig (CTLA4-Ig). METHODS:We divided BALB/C mice into the three groups: Sham/Sham (control), ovalbumin (OVA)/OVA and mCTLA4-Ig. Blood, bronchoalveolar lavage, histology ...

journal_title：Chinese medical journal

authors： Wan H,Zhou M,Xu Q,Huang S,Deng W

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:Pulsed radiofrequency (PRF) application to the dorsal root ganglia can reduce neuropathic pain (NP) in animal models, but the effect of PRF on damaged peripheral nerves has not been examined. We investigated the effect of PRF to the rat sciatic nerve (SN) on pain-related behavior and SN ultrastructure follow...

journal_title：Chinese medical journal

authors： Li DY,Meng L,Ji N,Luo F

更新日期：2015-02-20 00:00:00

abstract：Background:Facioscapulohumeral muscular dystrophy (FSHD) is characterized by asymmetric muscular deficit of facial, shoulder-girdle muscles, and descending to lower limb muscles, but it exists in several extramuscular manifestations or overlapping syndromes. Herein, we report a "complex disease plus" patient with FSHD1...

journal_title：Chinese medical journal

authors： Lin XD,He JJ,Lin F,Chen HZ,Xu LQ,Hu W,Cai NQ,Lin MT,Wang N,Wang ZQ,Xu GR

更新日期：2018-09-20 00:00:00

abstract：BACKGROUND:Although the use of hepatitis B immunoglobulin (HBIG) may lead to a significant reduction in recurrent hepatitis B virus (HBV) infection and improve the survival of patients who have undergone liver transplantation (LT) for hepatitis B-related diseases, the recurrence of the disease still remains at a lower ...

journal_title：Chinese medical journal

authors： Wang WL,Zhang GL,Wu LH,Yao MY,Jin J,Jia CK,Xie HY,Zhou L,Jiang ZJ,Zheng SS

更新日期：2007-09-20 00:00:00

abstract：:The solid pseudopapillary tumors of the pancreas (SPTP) are rare tumors, which are commonly found in adolescent women. Radical surgical resection of the primary tumor or metastases is the standard treatment for SPTP and could achieve long-term survival. We reported a case of a 20-year-old female with multiple liver me...

journal_title：Chinese medical journal

authors： Li JX,Wu H,Huang JW,Prasoon P,Zeng Y

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Chronic graft-versus-host disease (GVHD), the commonest long-term complication after allogeneic hematopoietic stem cell transplantation (HSCT), has a negative impact on patients' health related quality of life (HRQoL). This study was designed to investigate the HRQoL in patients with chronic GVHD in China. ...

journal_title：Chinese medical journal

authors： Mo XD,Xu LP,Liu DH,Chen YH,Zhang XH,Chen H,Han W,Wang Y,Wang FR,Wang JZ,Liu KY,Huang XJ

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Diffusion tensor imaging (DTI) permits quantitative examination within the pyramidal tract (PT) by measuring fractional anisotropy (FA). To the best of our knowledge, the inter-variability measures of FA along the PT remain unexplained. A clear understanding of these reference values would help radiologists ...

journal_title：Chinese medical journal

authors： Roldan-Valadez E,Rios-Piedra E,Favila R,Alcauter S,Rios C

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:To rapidly and economically obtain knowledge about adult stage Schistosoma japonicum (Chinese strain) expressed genes using expressed sequence tag (EST). METHODS:A directional cDNA library constructed from Schistosoma japonicum (Chinese strain) adult stage RNA was used to generate expressed sequence tags (ES...

journal_title：Chinese medical journal

authors： Bian G,Yu X,Wu Z

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:Urine output (UO) is an essential criterion of the Kidney Disease Improving Global Outcomes (KDIGO) definition and classification system for acute kidney injury (AKI), of which the diagnostic value has not been extensively studied. We aimed to determine whether AKI based on KDIGO UO criteria (KDIGOUO) could ...

journal_title：Chinese medical journal

authors： Qin JP,Yu XY,Qian CY,Li SS,Qin TH,Chen EZ,Lin JD,Ai YH,Wu DW,Liu DX,Sun RH,Hu ZJ,Cao XY,Zhou FC,He ZY,Zhou LH,An YZ,Kang Y,Ma XC,Zhao MY,Jiang L,Xu Y,Du B,China Critical Care Clinical Trial Group (CCCCTG).

更新日期：2016-09-05 00:00:00

abstract：BACKGROUND:In steroid-induced osteonecrosis, hypertrophy and hyperplasia of marrow fat cells and lipid deposition of osteocytes can be found in the femoral head. However, the precise reason is not clear yet. The aim of this study was to observe the effect of dexamethasone (Dex) on differentiation of marrow stromal cell...

journal_title：Chinese medical journal

authors： Yin L,Li YB,Wang YS

更新日期：2006-04-05 00:00:00

abstract：BACKGROUND:Nowadays, there is a remarkable rise in resectability rate of periampullary adenocarcinoma and the mortality and morbidity of the pancreaticoduodenectomy procedure have been reduced remarkably, while the 5 year survival rates of patients with carcinoma of the head of the pancreas are still below 25%. We cond...

journal_title：Chinese medical journal

authors： Yang YM,Wan YL,Tian XD,Zhuang Y,Huang YT

更新日期：2005-11-20 00:00:00

abstract：OBJECTIVE:To choose one optimal extrinsic positive end-expiratory pressure (PEEPe) for ventilated patients with chronic obstructive pulmonary disease (COPD) and to compare two methods for choosing the optimal level of PEEPe. METHODS:Ten ventilated patients with COPD were included in the study. First, static intrinsic ...

journal_title：Chinese medical journal

authors： Kong W,Wang C,Yang Y,Huang K,Jiang C

更新日期：2001-09-01 00:00:00

abstract：Background::Core fucosylation (CF), catalyzed by α-1,6 fucosyltransferase (Fut8) in mammals, plays an important role in pathological processes through posttranslational modification of key signaling receptor proteins, including transforming growth factor (TGF)-β receptors and platelet-derived growth factor (PDGF) recep...

journal_title：Chinese medical journal

authors： Li LK,Wang N,Wang WD,Du XN,Wen XY,Wang LY,Deng YY,Wang DP,Lin HL

更新日期：2017-09-20 00:00:00

abstract：OBJECTIVE:To observe the characteristics of coronary microvascular lesions (CML) in the autopsied elderly cases with hypertensive left ventricular hypertrophy (LVH) and the difference of CML among the groups of essential hypertension (EHT), coronary heart disease (CHD) and diabetes (NIDDM) also with LVH. METHODS:A ret...

journal_title：Chinese medical journal

authors： Li X,Li R,Yu W,Shi H,Wei L

更新日期：2002-05-01 00:00:00

abstract：OBJECTIVE:To observe the anti-injury role of recombinant human augmenter of liver regeneration. METHODS:To establish liver injury models induced by CCl4 in vivo and in vitro, cell survival rates and LDH release rates served as observing index in experiments in vitro. Survival rates of liver failure animals, serum conc...

journal_title：Chinese medical journal

authors： Yang X,Wang A,Zhou P,Wang Q,Wei H,Wu Z,He F

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND:Chronic hepatic inflammation is characterized by the accumulation of lymphocytes as a consequence of increased recruitment from the blood and retention within the tissue at sites of infection. CXC chemokine ligand 16 (CXCL16) mRNA has been detected in both inflamed and normal liver tissues and is strongly up...

journal_title：Chinese medical journal

authors： Wang P,Kan QC,Yu ZJ,Li L,Pan X

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Spinal cord injury (SCI) is a worldwide medical concern. This study aimed to elucidate the mechanism underlying the protective effect of hyperbaric oxygen (HBO) against SCI-induced neurologic defects in rats via exploring the stromal cell-derived factor-1 (SDF-1)/CXC chemokine receptor 4 (CXCR4) axis and exp...

journal_title：Chinese medical journal

authors： Meng XL,Hai Y,Zhang XN,Wang YS,Liu XH,Ma LL,Yue R,Xu G,Li Z

更新日期：2019-03-20 00:00:00

abstract：OBJECTIVE:To identify novel tumor suppressor genes at chromosome 3p24-26 in human nasopharyngeal carcinoma (NPC). METHODS:Twenty epithelial-derived expressed sequence tags (EST) were selected from chromosome 3p24-26. RT-PCR and Northern blot were used to detect the expression of the ESTs in NPC cell line, HNE-1, and p...

journal_title：Chinese medical journal

authors： Xie Y,Bin L,Yang J,Li Z,Yu Y,Zhang X,Cao L,Li G

更新日期：2001-05-01 00:00:00

abstract：OBJECTIVE:To investigate the influence of alveolar macrophages (AMs), fibroblasts and interstitial cells on development of lung fibrosis, and the interactions among TGF-beta 1 PDGF and IGF-1 and these cytokines-effects on lung fibrosis. MATERIAL AND METHODS:Expressions of TGF-beta 1, PDGF and IGF-1 mRNA in the lung ce...

journal_title：Chinese medical journal

authors： Li H,He B,Que C,Weng B

更新日期：1996-07-01 00:00:00

abstract：Objective:Acute respiratory distress syndrome (ARDS) is an acute and lethal clinical syndrome that is characterized by the injury of alveolar epithelium, which impairs active fluid transport in the lung, and impedes the reabsorption of edema fluid from the alveolar space. This review aimed to discuss the role of pro-re...

journal_title：Chinese medical journal

authors： Wang Q,Yan SF,Hao Y,Jin SW

更新日期：2018-04-20 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) is a growing public health problem with well-established risk factors. Other contributing factors, however, remain to be identified. Systemic inflammation in asthma plays a significant role in the development of other diseases. We therefore initiated a study to assess whether the...

journal_title：Chinese medical journal

authors： Liu DW,Zhen XG,Liang Y,Jing XG,Zhang TS,Zhang GJ,Liu ZS

更新日期：2013-11-01 00:00:00