Expression of TGF-beta 1, PDGF and IGF-1 mRNA in lung of bleomycin-A5-induced pulmonary fibrosis in rats.

abstract：Background:The role of postradiation systemic therapy in non-small cell lung cancer (NSCLC) patients with brain metastasis (BM) was controversial. Thus, we explored the role of Radiation Therapy Oncology Group recursive partitioning analysis (RTOG-RPA) and graded prognostic assessment (GPA) in identifying population wh...

journal_title：Chinese medical journal

authors： Liu S,Chen P,Liu YW,Gu XN,Qiu XG,Li B

更新日期：2018-05-20 00:00:00

abstract：BACKGROUND:While combined oral contraceptives (COCs) are commonly used to treat polycystic ovary syndrome (PCOS), comparative data regarding metabolic effects of different progestogens on this patient population are missing. This study aimed to compare the different effects of drospirenone (DRP)-containing COCs with cy...

journal_title：Chinese medical journal

authors： Wang QY,Song Y,Huang W,Xiao L,Wang QS,Feng GM

更新日期：2016-04-20 00:00:00

abstract：:A family with Fabry's disease including 2 hemizygotes and 3 heterozygotes is reported. The ocular manifestations include tortuosity of conjunctival vessels, Fabry's deposits underlying the anterior capsule of the lens and the whorl-like corneal dystrophy. Foam cells or mulberry cells in the urinary sediment and varyin...

journal_title：Chinese medical journal

authors： Bao LL,Guo LL,Li SN,Xiao J,Yang JS,Bai LR,Ye PM,Guo ZT,Liu DW

更新日期：1990-02-01 00:00:00

abstract：OBJECTIVE:To investigate the correlation among retinal fluorescein angiography, blood viscosity, and other factors in patients with open angle glaucoma (POAG). METHODS:Multiple step regression analysis was made to investigate the correlation between each of the following blood vessel filling times: the arm-choroid (A-...

journal_title：Chinese medical journal

authors： Liu X,Zhou W,Ye T,Ge J,Cai X,Cheng A,Lin Y,Liang L,Tang H,Chen Z

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:HIV-1 infected and immune-activated macrophages and microglia secrete neurotoxins, such as tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β), which play major role in the neuronal death. It has been shown that different HIV-1 variants have varying abilities to elicit secretion of TNF-α by peripheral...

journal_title：Chinese medical journal

authors： Yan YF,Wang ZY,Pu SS,Wen HL,Huang T,Song YY,Xu HZ,Zhao L

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Diffusion tensor imaging (DTI) permits quantitative examination within the pyramidal tract (PT) by measuring fractional anisotropy (FA). To the best of our knowledge, the inter-variability measures of FA along the PT remain unexplained. A clear understanding of these reference values would help radiologists ...

journal_title：Chinese medical journal

authors： Roldan-Valadez E,Rios-Piedra E,Favila R,Alcauter S,Rios C

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Von Hippel-Lindau (VHL) disease is a hereditary tumor disorder caused by mutations or deletions of the VHL gene. Few studies have documented the clinical phenotype and genetic basis of the occurrence of VHL disease in China. This study armed to present clinical and genetic analyses of VHL within a five-gener...

journal_title：Chinese medical journal

authors： Zhang J,Ma J,Du X,Wu D,Ai H,Bai J,Dong S,Yang Q,Qu K,Lyu Y,Valenzuela RK,Liu C

更新日期：2015-01-05 00:00:00

abstract：:One 22-month-old boy who was admitted for a fever lasting 6 days as well as a cough and wheezing lasting 2 days was reported. He was diagnosed with influenza A (H1N1, severe type), severe pneumonia, acute respiratory distress syndrome (ARDS), Evans syndrome and multiple organ failure. This is the first case of novel i...

journal_title：Chinese medical journal

authors： Chen H,Jia XL,Gao HM,Qian SY

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Tuberous sclerosis (TS) is an autosomal dominant disorder with a significant range of clinical expressions. The involvement of vital organs, such as the brain, kidney, heart and lung is the main cause of death in patients with TS. The aim of this study is to summarize the characteristic cutaneous features an...

journal_title：Chinese medical journal

authors： Sun XF,Yan CL,Fang L,Shen FM,Liao KH

更新日期：2005-02-05 00:00:00

abstract：:Eight strains of sonicated Helicobacter pylori (H. pylori) were pooled as group antigen to detect the serum IgG antibody to H. pylori in patients with various gastroduodenal diseases and subjects at health check-up. The enzyme-linked immunosorbent assay method used had a sensitivity of 94%, a specificity of 87%, and a...

journal_title：Chinese medical journal

authors： Xiao SD,Pan ZJ,Zhang ZH,Jiang SJ

更新日期：1991-11-01 00:00:00

abstract：BACKGROUND:Studies have shown that β-blockers can improve cardiac performance in heart failure (HF) by reversing protein kinase A (PKA)-mediated sarcoplasmic reticulum (SR) Ca2+ leak. However, it is being strongly questioned as to whether the PKA-mediated ryanodine receptor (RyR2) hyper-phosphorylation is a critical re...

journal_title：Chinese medical journal

authors： Zhang SJ,Liu ZH,Zou C,Wang L

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVE:To investigate an method for hepatic differentiation from embryonic stem cells (ES cells) in vitro and the resulting differentiation ratio, in order to develop a procedure for producing a new type of hepatocyte for hepatocyte replacement therapy in the treatment of liver failure. METHODS:ES cells from Balb/C...

journal_title：Chinese medical journal

authors： Hu A,Cai J,Zheng Q,He X,Pan Y,Li L

更新日期：2003-12-01 00:00:00

abstract：OBJECTIVE:To study the expression of vascular endothelial growth factor (VEGF) in different parts of heart during early acute myocardial ischemia. METHODS:The expression of VEGF in control and study group in rats was performed with the Strept Avidin-Biotin-Peroxidase Complex (SABC) method. RESULTS:A rapid expression ...

journal_title：Chinese medical journal

authors： Chen J,Xu X,Wu X,Zhu J

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:Nasopharyngeal carcinoma (NPC) is a squamous-cell carcinoma especially prevailing among the natives of southern China. The regimen of concurrent chemoradiotherapy (CCRT) that include platinum and 5-fluorouracil (5-FU) is considered to be the standard treatment for NPC. However, its clinical use is limited by...

journal_title：Chinese medical journal

authors： Chen X,Hong Y,Feng J,Ye J,Zheng P,Guan X,You X,Song H

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Pancreatic cancer is a highly malignant tumor affecting an ever increasing number of patients with a mean 5-year survival rate below 4%. Therefore, gene therapy for cancer has become a potential novel therapeutic modality. In this study we sought to determine the inhibitory effects of adenovirus-mediated hum...

journal_title：Chinese medical journal

authors： Pan XT,Zhu QY,Li DC,Yang JC,Zhang ZX,Zhu XG,Zhao H

更新日期：2008-10-20 00:00:00

abstract：:This is China's pilot study in the assessment of the diagnostic value of serum soluble IL-2 receptor (sIL-2R) in gastric cancer. We measured its level by ELISA method in 45 patients with gastric cancer (without metastasis: 32; with metastasis: 5; recurrence: 8) 27 gastric ulcer, 27 superficial gastritis and 44 healthy...

journal_title：Chinese medical journal

authors： Wang YF,Wu XN,Zhou YH,Chen XF,Shen J,Wang HJ

更新日期：1994-04-01 00:00:00

abstract：:It is difficult to make a precise diagnosis of intestinal tuberculosis and to differentiate it from Crohn's disease. For evaluating Polymerase Chain Reaction (PCR) assay in these two aspects, 36 specimens of intestinal tuberculosis from surgical resections and endoscopic biopsies and 26 Crohn's disease samples were su...

journal_title：Chinese medical journal

authors： Gan H,Ouyang Q,Bu H,Li S,Chen D,Li G,Yang X

更新日期：1995-03-01 00:00:00

abstract：:The results of 31 cases of sutureless esophagogastrostomy by intraluminal elastic circular ligation (IECL) with the biodegradable supporting tube were reported. The fate of the supporting tube could be tracked satisfactorily by X-ray. The tube-dislodge time was 15.03 +/- 2.23 days and unaffected by the size of support...

journal_title：Chinese medical journal

authors： Chen L,Zhang Y,Du X,Wang Q,Zhang Z

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND:Mesenchymal stem or stromal cells (MSCs) derived from the induced pluripotent stem cells (iPSCs) have uniform biological activity, which makes the clinical application of MSCs in bone repair possible. Culturing the iPSC-MSCs onto osteoconductive materials is a promising tissue engineering-based strategy in b...

journal_title：Chinese medical journal

authors： Li JY,Wang TT,Li C,Wang ZF,Li S,Ma L,Zheng LL

更新日期：2020-02-05 00:00:00

abstract：OBJECTIVE:To investigate CTLA4-Ig's potential role in therapy for allergic asthma by blocking B7/CD28 interactions with cytotoxic T lymphocyte antigen 4-Ig (CTLA4-Ig). METHODS:We divided BALB/C mice into the three groups: Sham/Sham (control), ovalbumin (OVA)/OVA and mCTLA4-Ig. Blood, bronchoalveolar lavage, histology ...

journal_title：Chinese medical journal

authors： Wan H,Zhou M,Xu Q,Huang S,Deng W

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVE:To investigate the relationship between the expression and regulation of osteopontin (OPN) and urolithiasis. METHODS:Normal and stone model rats were treated with 1,25-dihydroxyvitamin D3(D3), vitamin K, testosterone or estradiol for 7 days, and the expression of osteopontin and its mRNA were detected with i...

journal_title：Chinese medical journal

authors： Chang L,Feng T,Li J,Dou C,Wei J,Guo Y

更新日期：2001-08-01 00:00:00

abstract：OBJECTIVE:To provide an overview of the current knowledge of growth-differentiation factor 15 (GDF-15) in heart disease. DATA SOURCES:To identify relevant publications, we searched PubMED database combining the textual terms of heart, cardiac, cardiovascular disease with GDF-15. STUDY SELECTION:Well-controlled, relat...

journal_title：Chinese medical journal

authors： Liu HT,Wang HC,Tao L,Li CX,Li F,Zhang YY,Liu BW

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:The present study was aimed to investigate the usage of aspirin for the secondary prevention of ischemic stroke, evaluate the correlated factors, and analyze the reasons for not taking and irregularly taking aspirin. METHODS:The patients in this group were all stroke survivors who have formerly been diagnos...

journal_title：Chinese medical journal

authors： Ke XJ,Yu YF,Guo ZL,Xu K,Hai H,Zhang AH,Jiang H,Peng H

更新日期：2009-01-20 00:00:00

abstract：BACKGROUND:The mortality of stroke patients is strongly affected by medical complications. However, there are limited data investigating the effect of in-hospital medical complications on the dependency of stroke patients worldwide. We prospectively and systematically investigated the effect of medical complications on...

journal_title：Chinese medical journal

authors： Wang PL,Zhao XQ,DU WL,Wang AX,Ji RJ,Yang ZH,Wang CX,Liu LP,Wang YL,Ju Y,Wang YJ,China National Stroke Registry (CNSR) investigators.

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:To investigate the mechanism of multidrug resistance (MDR) in a human glioma cell and methods for overcoming multi-drug resistance. METHODS:MDR cell line C(6)/adr was established. The expression of the mdr-1 gene and its P-glycoprotein (P-gp) in the C(6)/adr cell line was observed by RT-PCR and flow cytometr...

journal_title：Chinese medical journal

authors： Liu F,Wang C,Zhang Q,Li J,Zhang Y

更新日期：2002-02-01 00:00:00

abstract：OBJECTIVE:To characterize the mRNA expression of CXC chemokine IL-8, CC chemokine monocyte chemothractant protein-1 (MCP-1) and regulated on activation, normal T cell expressed and secreted (RANTES), and a newly defined DC chemokine DC-CK1 as well as the expression of IL-8 receptor, MCP-1 receptor and RANTES receptor i...

journal_title：Chinese medical journal

authors： Zhu K,Shen Q,Ulrich M,Zheng M

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND:Antiphospholipid syndrome (APS)-related immune factors are considered as an important cause of recurrent spontaneous abortion (RSA). Anticoagulant and anti-inflammatory treatments are believed to effectively improve adverse pregnancy outcomes by affecting the abnormal autoimmune response of the maternal-feta...

journal_title：Chinese medical journal

authors： Ye SL,Gu XK,Tao LY,Cong JM,Wang YQ

更新日期：2017-06-20 00:00:00

abstract：OBJECTIVE:To focus on the asthmatic pathogenesis and clinical manifestations related to epithelial sodium channel (ENaC)/chlorine ion channel. DATA SOURCES:The data analyzed in this review were the English articles from 1980 to 2015 from journal databases, primarily PubMed and Google Scholar. The terms used in the lit...

journal_title：Chinese medical journal

authors： Wang W,Ji HL

更新日期：2015-08-20 00:00:00

abstract：Background:Development of innovative immunotherapy is imperative to improve the poor survival of the nasopharyngeal carcinoma (NPC) patients. In this study, we evaluated the T cell response to melanoma-associated antigen (MAGE)-A1, MAGE-A3, or synovial sarcoma X-2 (SSX-2) in the peripheral blood of treatment-naive NPC ...

journal_title：Chinese medical journal

authors： Fan PW,Huang L,Chang XM,Feng YN,Yao X,Peng YC,Dong T,Wang RZ

更新日期：2018-06-05 00:00:00

abstract：BACKGROUND:In 2012, the working group on abdominal problems of the European Society of Intensive Care Medicine (ESICM) proposed a definition and also guidelines for the grading system and treatment of acute gastrointestinal injury (AGI). Until now, clinical reports on this topic have not been available, and the practic...

journal_title：Chinese medical journal

authors： Zhang D,Li N,Dong L,Fu Y,Liu Z,Wang Y

更新日期：2014-01-01 00:00:00