Clinical characteristics of human infection with a novel avian-origin influenza A(H10N8) virus.

Abstract:

BACKGROUND:Novel influenza A viruses of avian-origin may be the precursors of pandemic strains. This descriptive study aims to introduce a novel avian-origin influenza A (H10N8) virus which can infect humans and cause severe diseases. METHODS:Collecting clinical data of three cases of human infection with a novel reassortment avian influenza A (H10N8) virus in Nanchang, Jiangxi Province, China. RESULTS:Three cases of human infection with a new reassortment avian influenza A(H10N8) virus were described, of which two were fatal cases, and one was severe case. These cases presented with severe pneumonia that progressed to acute respiratory distress syndrome (ARDS) and intractable respiratory failure. CONCLUSION:This novel reassortment avian influenza A (H10N8) virus in China resulted in fatal human infections, and should be added to concerns in clinical practice.

journal_name

Chin Med J (Engl)

journal_title

Chinese medical journal

authors

Zhang W,Wan J,Qian K,Liu X,Xiao Z,Sun J,Zeng Z,Wang Q,Zhang J,Jiang G,Nie C,Jiang R,Ding C,Li R,Horby P,Gao Z

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

3238-42

issue

18

eissn

0366-6999

issn

2542-5641

journal_volume

127

pub_type

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