Abstract:
:This paper reports the results of serological survey of 318,912 persons for nasopharyngeal carcinoma (NPC) in 21 cities and counties of south China. There were 8,441 persons with positive VCA-IgA antibody (single item positive) of EB virus (EBV), with a rate of 2.65%. In these VCA-IgA positive persons, 287 persons also had positive EA-IgA (double items positive) of EBV. The overall positive rate was 0.09%. 100 cases of NPC were found and 87 of them (87.0%) were in early stage. NPC found in the group with single item positive accounts for 1.19%, but the rate in the group with double items positive was 19.16% (55 cases). In NPC patients with double items positive, 49 cases were in early stage (89.1%). In 100 cases of NPC found, 45 cases appeared with negative EA-IgA, only with positive VCA-IgA, which indicated that for diagnosis of NPC, sensitivity of EA-IgA was lower than that of VCA-IgA, but its specificity was higher. Therefore, both can increase the detecting rate and early diagnosis rate of NPC. The age of people checked varied with different antibody positive rate and NPC detecting rate. The three items showed a positive correlation. The results are compatible with those of the prospective study for NPC in Wuzhou City, Guangxi, China. The method for NPC serological diagnosis can be extended and applied to raise the NPC detecting rate and early diagnosis rate at secondary prevention. And, it is further proved that there is a close relationship between NPC and EBV.
journal_name
Chin Med J (Engl)journal_title
Chinese medical journalauthors
Deng H,Zeng Y,Lei Y,Zhao Z,Wang P,Li B,Pi Z,Tan B,Zheng Y,Pan Wsubject
Has Abstract,Author List Incompletepub_date
1995-04-01 00:00:00pages
300-3issue
4eissn
0366-6999issn
2542-5641journal_volume
108pub_type
杂志文章,多中心研究abstract:OBJECTIVE:To study the relationship between cartilage end-plate calcification and intervertebral disc degeneration. METHODS:An experimental model of cervical disc degeneration in rabbits was established by resection of the cervical supraspinous and interspinous ligaments and detachment of the posterior paravertebral m...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:2001-03-01 00:00:00
abstract:OBJECTIVE:To analysis the pathological demography in Chinese patients undergoing renal biopsy from our nephrology center. METHODS:Between January 1979 and October 2000 in Jinling Hospital, Nanjing, China, 10,002 attempts of percutaneous renal were performed in patients with renal disease from 33 provinces of China. Th...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:2003-09-01 00:00:00
abstract:BACKGROUND:It is important to choose an appropriate antiepileptic drug (AED) to manage partial epilepsy. Traditional AEDs, such as carbamazepine (CBZ) and valproate (VPA), have been proven to have good therapeutic effects. However, in recent years, a variety of new AEDs have increasingly been used as first-line treatme...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:10.4103/0366-6999.168968
更新日期:2015-11-20 00:00:00
abstract:OBJECTIVE:To explore the effects of ultrafiltration technique in preventing and relieving pulmonary injury in children undergoing open heart surgery and cardiopulmonary bypass (CPB). METHODS:Thirty cases with congenital heart defects were divided into a control group and an experimental group. In the control group, co...
journal_title:Chinese medical journal
pub_type: 临床试验,杂志文章
doi:
更新日期:2003-10-01 00:00:00
abstract:BACKGROUND:To compare the efficacy and safety of hormone replacement therapy (HRT) combined with fluoxetine, with HRT alone, in post-menopausal women suffering from depression. METHODS:A randomized, open-label, parallel trial was applied. HRT was administered to all patients for 2 cycles, with 14 days of estrogen ther...
journal_title:Chinese medical journal
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2004-02-01 00:00:00
abstract:OBJECTIVE:To assess the existence of a possible infectious factor in varicocele-related infertility. METHODS:A total of 925 seminal plasmas from 590 infertile men with varicocele and 335 infertile patients without palpable varicocele were cultured for Ureaplasma urealyticum infection, and routine semen analysis was ma...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:1997-11-01 00:00:00
abstract:BACKGROUND:The primary ovarian sarcoma is a very rare malignancy. The objective of this study was to further investigate the clinicopathologic features and outcome in patients with primary sarcoma of the ovary. METHODS:Between 1988 and 2007, 24 patients with primary ovarian sarcoma who underwent treatment at Peking Un...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVE:To provide epidemiological data for revising the diagnostic criteria of neonatal hyperbilirubinemia in China. METHODS:A survey was performed among full-term infants in multiple centers throughout the country. From less than 24 hours after birth, the infants' bilirubin levels were measured every day until the...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:2001-04-01 00:00:00
abstract:OBJECTIVE:To investigate the effectiveness of using a medium molecular weight hydroxyethyl starch solution (HES) administered as a replacement for estimated blood loss (EBL) during cytoreductive surgery for ovarian cancer on splanchnic oxygenation. METHODS:Forty-two patients undergoing cytoreductive surgery for ovaria...
journal_title:Chinese medical journal
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2003-07-01 00:00:00
abstract:BACKGROUND:To date, there have been no reports on altered nitric oxide (NO) content in ischemia/reperfusion with regard to in vivo preconditioning procedures. These studies are important for understanding the mechanisms of NO during early myocardial ischemic preconditioning. The aim of the present study was to investig...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:2008-07-05 00:00:00
abstract:BACKGROUND:Current treatments for scoliosis have some defects and complications. To study spinal deformities and test novel scoliosis treatments, many animal models of scoliosis have been developed. These models applied a single load to the spine and could not precisely modulate the spinal growth in different dimension...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:10.4103/0366-6999.213910
更新日期:2017-11-05 00:00:00
abstract:OBJECTIVE:To introduce the applied anatomy of pedicled buccal fat pad (BFP) graft and a series of histological changes in the healing process of BFP as an uncovered pedicled graft. METHODS:The healing processes of BFP are demonstrated via uncovered pedicled grafts on rabbits in histological examination. Uncovered bucc...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:2002-10-01 00:00:00
abstract:BACKGROUND:Allergic rhinitis (AR) is a Th2 dominant cytokine response. Chloride channel-3 (ClC-3) plays an important role in nasal mucosal edema and inflammatory pathologic changes in AR. Antiallergic herbal agents (AHA) are antiallergic herbal products. In the previous study, we have demonstrated that AHA clearly inhi...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:2010-04-20 00:00:00
abstract::Cogan’s syndrome (CS) is a rare inflammatory disorder characterized by interstitial keratitis and vestibuloauditory abnormalities often associated with various systemic manifestations. Involvement of cardiovascular system resembling systemic vasculitis may lead to severe complications and death. The present report des...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:2011-10-01 00:00:00
abstract:BACKGROUND:Pleomorphic hyalinizing angiectatic tumor (PHAT) of soft parts is a rare soft tissue tumor, which is generally considered low-grade. To distinguish the tumor from other soft tissue lesions, we analyzed the clinicopathologic and ultrastructural features, immunophenotypes, and flow cytometric DNA ploidy of PHA...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:2007-05-20 00:00:00
abstract:BACKGROUND:In central precocious puberty (CPP), the pulse secretion and release of gonadotropin-releasing hormone (GnRH) are increased due to early activation of the hypothalamic-pituitary-gonadal axis, resulting in developmental abnormalities with gonadal development and appearance of secondary sexual characteristics....
journal_title:Chinese medical journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.4103/0366-6999.156773
更新日期:2015-05-20 00:00:00
abstract:BACKGROUND:There are relatively few reports focusing on clinical and multi-slice CT (MSCT) imaging findings of mucinous tubular and spindle cell carcinoma (MTSCC). Our study aimed to characterize the clinical and MSCT imaging features of MTSCC. METHODS:The imaging findings in 17 patients with MTSCC by MSCT were retros...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Although previous reports had reported the use of temporary internal distraction as an aid to correct severe scoliosis, two-stage surgery strategy (less invasive internal distraction followed by posterior correction and instrumentation) has never been reported in the treatment of patients with severe spinal ...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVE:To assess the effects of Dy-DTPA-BMA (sprodiamide) on ex-vivo MR imaging of reperfused acute myocardial infarction. METHODS:Eighteen dogs were subjected to 2-hour coronary artery occlusion followed by 24-hour reperfusion. Dysprosium-chelate (Dy-DTPA-BMA) was injected into 16 dogs. Twenty minutes before their...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:2000-03-01 00:00:00
abstract:BACKGROUND:Urolithiasis in pediatric population is a serious problem with the incidence increased these years. In the management of larger stones (diameters >2 cm), percutaneous nephrolithotomy (PCNL) is considered to be the gold standard. This study aimed to investigate the efficacy and safety of mini-PCNL under total...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:10.4103/0366-6999.158312
更新日期:2015-06-20 00:00:00
abstract:OBJECTIVE:To investigate the mechanism of multidrug resistance (MDR) in a human glioma cell and methods for overcoming multi-drug resistance. METHODS:MDR cell line C(6)/adr was established. The expression of the mdr-1 gene and its P-glycoprotein (P-gp) in the C(6)/adr cell line was observed by RT-PCR and flow cytometr...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:10.3901/jme.2002.supp.238
更新日期:2002-02-01 00:00:00
abstract:BACKGROUND:Previous studies have suggested that primary degeneration of hair cells causes secondary degeneration of spiral ganglion neurons (SGNs), but the effect of SGN degeneration on hair cells has not been studied. In the adult mouse inner ear ouabain can selectively and permanently induce the degeneration of type ...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Muscle fibers overlying the intramyocardial segment of an epicardial coronary artery are termed myocardial bridging (MB). Variable prevalence of MB has been described at autopsy and angiographic series with small and large sample size studies. In addition, no similar study was reported in Chinese population....
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:2008-03-05 00:00:00
abstract:BACKGROUND:Although the use of hepatitis B immunoglobulin (HBIG) may lead to a significant reduction in recurrent hepatitis B virus (HBV) infection and improve the survival of patients who have undergone liver transplantation (LT) for hepatitis B-related diseases, the recurrence of the disease still remains at a lower ...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:2007-09-20 00:00:00
abstract:BACKGROUND:The second-trimester maternal serum screening in twin pregnancy is still controversial, as the serum marker levels in twins are not as clear as those in singletons. This study aimed to evaluate the relationship between the levels of the second-trimester maternal serum free beta-human chorionic gonadotropin (...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:2010-03-05 00:00:00
abstract:OBJECTIVE:To evaluate the efficacy and safety of misoprostol in term labour induction. DATA SOURCES:Data from published English and Chinese literatures about misoprostol in term labour induction were identified from Medline and CBMdisk (using the search terms "misoprostol" and "labour induction") before 2001; hand sea...
journal_title:Chinese medical journal
pub_type: 杂志文章,meta分析,评审
doi:
更新日期:2004-03-01 00:00:00
abstract:OBJECTIVE:To investigate the prevalence and features of active human cytomegalovirus (HCMV) infection in children with systemic lupus erythematosus (SLE) and evaluate the diagnostic value of the HCMV using antigenemia assay, serum polymerase chain reaction (PCR) and serology test. METHODS:Twenty-one SLE children under...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:2001-12-01 00:00:00
abstract:BACKGROUND:Severe acute respiratory syndrome (SARS) is a disease with a mortality of 9.56%. Although SARS is etiologically linked to a new coronavirus (SARS-CoV) and functional cell receptor has been identified, the pathogenesis of the virus infection is largely unclear. METHODS:The clinical specimens were processed a...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:2008-04-05 00:00:00
abstract:BACKGROUND:This prospective, randomized, controlled study was designed to investigate the effects of a diabetes specific formula (Diason low energy: 313.8 kJ/100 ml), compared with a standard formula, on insulin sensitivity, serum C peptide, serum lipids and free fatty acid (FFA) in type 2 diabetics. METHODS:In total ...
journal_title:Chinese medical journal
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2008-04-20 00:00:00
abstract:BACKGROUND:In the past 5 years, new treatment materials and techniques offering a different concept in endovascular treatment have been described for cerebral arteriovenous malformations (CAVMs). The aim of this study was to assess the endovascular treatment of CAVMs by using a liquid embolic material, Onyx (Micro Ther...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:2005-12-20 00:00:00