Atypical Cogan's syndrome associated with coronary disease.

Abstract:

:Cogan’s syndrome (CS) is a rare inflammatory disorder characterized by interstitial keratitis and vestibuloauditory abnormalities often associated with various systemic manifestations. Involvement of cardiovascular system resembling systemic vasculitis may lead to severe complications and death. The present report describes a case of a female patient with atypical Cogan's syndrome presented with systemic manifestations and severe coronary and femoral artery stenosis. Despite the clinical improvement after glucocorticoids and cyclophosphamide, the patient required double aortocoronal bypass grafting one year letter. During three years follow-up, she was in stable condition, without stenocardial symptoms and claudication and her inflammatory parameters remain normal. This case highlights the rare involvement of coronary arteries without associated large-vessel vasculitis of the aortic arch in CS.

journal_name

Chin Med J (Engl)

journal_title

Chinese medical journal

authors

Branislava I,Marijana T,Nemanja D,Dragan S,Maja Z

subject

Has Abstract

pub_date

2011-10-01 00:00:00

pages

3192-4

issue

19

eissn

0366-6999

issn

2542-5641

journal_volume

124

pub_type

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