Abstract:
:Cogan’s syndrome (CS) is a rare inflammatory disorder characterized by interstitial keratitis and vestibuloauditory abnormalities often associated with various systemic manifestations. Involvement of cardiovascular system resembling systemic vasculitis may lead to severe complications and death. The present report describes a case of a female patient with atypical Cogan's syndrome presented with systemic manifestations and severe coronary and femoral artery stenosis. Despite the clinical improvement after glucocorticoids and cyclophosphamide, the patient required double aortocoronal bypass grafting one year letter. During three years follow-up, she was in stable condition, without stenocardial symptoms and claudication and her inflammatory parameters remain normal. This case highlights the rare involvement of coronary arteries without associated large-vessel vasculitis of the aortic arch in CS.
journal_name
Chin Med J (Engl)journal_title
Chinese medical journalauthors
Branislava I,Marijana T,Nemanja D,Dragan S,Maja Zsubject
Has Abstractpub_date
2011-10-01 00:00:00pages
3192-4issue
19eissn
0366-6999issn
2542-5641journal_volume
124pub_type
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