A randomized control trial on interruption of HBV transmission in uterus.

abstract：BACKGROUND:Aerosolized amikacin (AA) is a current option for the management of ventilator-associated pneumonia (VAP) caused by multidrug-resistant Gram-negative bacteria (MDR-GNB), as it is reported that AA could increase the alveolar level of the drug without increasing systemic toxicity. This study aimed to evaluate ...

journal_title：Chinese medical journal

authors： Liu C,Zhang YT,Peng ZY,Zhou Q,Hu B,Zhou H,Li JG

更新日期：2017-05-20 00:00:00

abstract：BACKGROUND:Although there were several clinical and experimental studies discussing the pathogenesis of dural arteriovenous fistula (DAVF), the pathological process leading to intracranial DAVF so far remains unknown. In this study, we investigated the expression of vascular growth factors in order to elucidate the pos...

journal_title：Chinese medical journal

authors： Tirakotai W,Bian LG,Bertalanffy H,Siegfried B,Sure U

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:It is still controversial as to the implementation of higher positive end-expiratory pressure (PEEP) in patients with acute respiratory distress syndrome (ARDS). This study was conducted to compare the lower and higher PEEP in patients with ARDS ventilated with low tidal volume, to investigate the relationsh...

journal_title：Chinese medical journal

authors： Guo FM,Ding JJ,Su X,Xu HY,Shi Y

更新日期：2008-11-20 00:00:00

abstract：BACKGROUND:The conventional method cannot guarantee the precise osteotomies required for a perfect realignment and a better prognosis after total knee arthroplasty (TKA). This study investigated a customized guide plate for osteotomy placement in TKAs with the aid of the statistical shape model technique using weight-b...

journal_title：Chinese medical journal

authors： Zhang J,Tian XB,Sun L,Hu RY,Tian JL,Han W,Zhao JM

更新日期：2016-02-20 00:00:00

abstract：BACKGROUND:Chronic liver disease causes aberrant formation of fibrous tissue that impedes normal liver function, ultimately resulting in liver cirrhosis. Iron uptake can occur within the hepatic parenchyma or within the various nodules that form in a cirrhotic liver, termed siderotic nodules (SN). We aimed to investiga...

journal_title：Chinese medical journal

authors： Tao R,You ZL,Zhang JQ,Dai YM,Zhou DQ,Cai P,Fan Y,Cui JG,Wang J

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVE:To characterize effects of the GP Ib alpha mutation (A156V) on its interaction with von Willebrand factor (vWf) under high fluid shear stress. METHODS:The residue A156 of GP Ib alpha was converted to a valine and the mutant expressed in CHO cells expressing wild-type GP Ib beta and GPIX. The transfected cell...

journal_title：Chinese medical journal

authors： Dong J,Li C,Schade AJ,Fredrickson BJ,Sun L,McIntire LV,López JA

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate the potential relationship between the dynamic expression of Toll-like receptor 2 and 4 (TLR2/4) in peripheral blood mononuclear cells as well as changes in serum concentration of inflammatory factors and acute lung injury (ALI) in patients after orthotopic liver tran...

journal_title：Chinese medical journal

authors： Chi XJ,Cai J,Luo CF,Cheng N,Hei ZQ,Li SR,Luo GJ

更新日期：2009-04-20 00:00:00

abstract：BACKGROUND:Sacroiliac (SI) screw fixation is a demanding technique, with a high rate of screw malposition due to the complex pelvic anatomy. TiRobot™ is an orthopedic surgery robot which can be used for SI screw fixation. This study aimed to evaluate the accuracy of robot-assisted placement of SI screws compared with a...

journal_title：Chinese medical journal

authors： Wang JQ,Wang Y,Feng Y,Han W,Su YG,Liu WY,Zhang WJ,Wu XB,Wang MY,Fan YB

更新日期：2017-11-05 00:00:00

abstract：:Recombinant DNA Yeast-Derived Hepatitis B Vaccine (RYHB vaccine) is comparable to and can replace Plasma-Derived Hepatitis B Vaccine (PHB vaccine) for the prevention of mother-infant transmission of hepatitis B virus (HBV), but the duration of immune efficacy of RYHB vaccine is not clear. This study indicates the long...

journal_title：Chinese medical journal

authors： Zhu QR,Gu XH,Duan SC,Xu HF

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:Occult stress urinary incontinence may lead to de novo stress urinary incontinence after pelvic floor repair surgery. A measurement of pudendal nerve terminal motor latency can reflect the integrity of the nerves. We aimed to explore the value of pudendal nerve terminal motor latency in the diagnosis of occu...

journal_title：Chinese medical journal

authors： Zhu L,Hai N,Lang JH,Yu SY,Li B,Wong F

更新日期：2011-12-01 00:00:00

abstract：:Increasing numbers of targeted drugs are used in hormone receptor (HR)-positive metastatic breast cancer (MBC) to overcome or delay resistance to endocrine therapy. This study will systemically review the progress made in endocrine therapy combined with targeted therapy in the treatment of HR-positive MBC. From the "A...

journal_title：Chinese medical journal

authors： Bian L,Xu FR,Jiang ZF

更新日期：2020-10-05 00:00:00

abstract：BACKGROUND:Volatile anesthetics (VAs) may affect varied and complex physiology processes by manipulating Ca(2+)-calmodulin (CaM). However, the detailed mechanism about the action of VAs on CaM has not been elucidated. This study was undertaken to examine the effects of VAs on the conformational change, hydrophobic site...

journal_title：Chinese medical journal

authors： Zhou MM,Xia HM,Liu J,Xu YN,Xin NX,Zhang SH

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:In central precocious puberty (CPP), the pulse secretion and release of gonadotropin-releasing hormone (GnRH) are increased due to early activation of the hypothalamic-pituitary-gonadal axis, resulting in developmental abnormalities with gonadal development and appearance of secondary sexual characteristics....

journal_title：Chinese medical journal

authors： Li WJ,Gong CX,Guo MJ,Xing J,Li T,Song WH,Luo XP,Wu D,Liang JP,Cao BY,Gu Y,Su C,Liang XJ,Liu M,Wang R,Li FT

更新日期：2015-05-20 00:00:00

abstract：BACKGROUND:Laser in situ keratomileusis (LASIK) has become an efficient and commonly performed procedure to reduce refractive errors. In order to further increase the postoperative visual quality, the wavefront-guided refractive surgery has been a research hotspot in customized surgery. This study was conducted to comp...

journal_title：Chinese medical journal

authors： Zhang J,Zhou YH,Wang NL,Li R

更新日期：2008-01-20 00:00:00

abstract：BACKGROUND:Previous studies demonstrated that vagus nerve stimulation (VNS) is an effective therapy for drug-resistant epilepsy. Acupuncture is also used to treat epilepsy. This study was designed to examine the safety and effectiveness of transcutaneous auricular vagus nerve stimulation (ta-VNS) for patients with drug...

journal_title：Chinese medical journal

authors： Rong P,Liu A,Zhang J,Wang Y,Yang A,Li L,Ben H,Li L,Liu R,He W,Liu H,Huang F,Li X,Wu P,Zhu B

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Visfatin, a visceral fat-derived adipocytokine, plays a significant physiological function in lipid metabolism. However, the precise function of visfatin and its regulation by thyroid hormones are still unknown. This study observed the plasma visfatin concentrations in subjects with hyperthyroidism and hypot...

journal_title：Chinese medical journal

authors： Han J,Zhang TO,Xiao WH,Chang CQ,Ai H

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Apoptosis is a major cause of ischemic heart dysfunction. Apelin, the endogenous ligand for the G-protein-coupled APJ receptor, has been reported to exert cardioprotective effects during myocardial injury. The aim of this study was to investigate the effects of apelin on apoptosis of rat cardiomyocytes induc...

journal_title：Chinese medical journal

authors： Zhang Z,Yu B,Tao GZ

更新日期：2009-10-05 00:00:00

abstract：OBJECTIVE:To investigate the short- and long-term clinician and angiographic outcome of stenting or angioplasty for chronic total coronary artery occlusion. METHODS:A total of 95 patients with successful percutaneous transluminal coronary angioplasty (PTCA) for total occlusion coronary artery were identified out of 35...

journal_title：Chinese medical journal

authors： Dong S,Jeong M,Cho J,Kang J

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Patients with temporal lobe epilepsy (TLE) originating from different seizure onset zones had distinct electrophysiological characteristics and surgical outcomes. In this study, we aimed to investigate the relationship between the origin and prognosis of TLE, and the stereoelectroencephalography (SEEG) featu...

journal_title：Chinese medical journal

authors： Yan XM,Xu CP,Wang YP,Ma K,Yu T,Zhang XH,Zhang X,Gao RS,Zhang GJ,Li YJ

更新日期：2020-12-02 00:00:00

abstract：BACKGROUND:This retrospective study aimed to investigate the difference of the intra-dural reserving space for spinal cord in magnetic resonance imaging (MRI) between patients with and without developmental cervical stenosis and its clinical significance. METHODS:A total of 264 patients with cervical spondylotic myelo...

journal_title：Chinese medical journal

authors： Tang Y,Yu M,Liu Z,Sun Y,Liu X

更新日期：2014-01-01 00:00:00

abstract：:Eighteen patients with acute hemorrhagic necrotizing pancreatitis who survived from operation were followed up for 12 to 43 months. Late complications including pancreatic external fistula, pseudocyst, hyperglycemia, etc were reviewed. The pancreatic juice was collected through endoscopic cannulation. The volume and H...

journal_title：Chinese medical journal

authors： Huang YT,Liu Q,Zhang BS

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND:Stenting a bifurcation lesion is technically challenging. No study has reported the clinical outcome of a dedicated bifurcation stent in China. We aimed to analyze the safety and clinical outcome of a novel side branch ostial stent (BIGUARD) stent in treating coronary bifurcation lesions. METHODS:Forty-seve...

journal_title：Chinese medical journal

authors： Chen SL,Zhang JJ,Ye F

更新日期：2009-09-20 00:00:00

abstract：BACKGROUND:Angiopoietin-2 (Ang-2) is one of the critical regulators of tumor angiogenesis. Studies have shown a significant correlation of Ang-2 expression to tumor invasion and metastasis in various human cancers, but little is known about the serum Ang-2 (sAng-2) levels in esophageal squamous cell cancer (ESCC) and i...

journal_title：Chinese medical journal

authors： Zhou YZ,Fang XQ,Li H,Diao YT,Yang YF,Zhao DL,Wu K,Li HQ

更新日期：2007-07-20 00:00:00

abstract：BACKGROUND:Preeclampsia, characterized by hypertension and proteinuria, is a multifactorial disease associated with shallow invasion of trophoblast cells and inadequate spiral artery remodeling. Trophoblast and tumor cells have similar invasion mechanism. Prostasin is closely related to tumor development, invasion and ...

journal_title：Chinese medical journal

authors： Luo D,Zhang Y,Bai Y,Liu X,Gong Y,Zhou B,Zhang L,Luo L,Zhou R

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Whether antibody to myelin oligodendrocyte glycoprotein (MOG) can be a diagnostic marker for multiple sclerosis (MS) is still controversial. Recent studies suggested that serum specific anti-MOG epitope antibody might be an MS specific marker. However, these studies did not include neuromyelitis optica (NMO)...

journal_title：Chinese medical journal

authors： Xu Y,Zhang Y,Liu CY,Peng B,Wang JM,Zhang XJ,Li HF,Cui LY

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Increasing prevalence of Staphylococcus aureus (S. aureus), particularly methicillin-resistant S. aureus (MRSA) has been reported in China. In this study, we investigated the drug resistance characteristic, genetic background, and molecular epidemiological characteristic of S. aureus in Changsha. METHODS:Be...

journal_title：Chinese medical journal

authors： Zou MX,Zhou RR,Wu WJ,Zhang NJ,Liu WE,Hu FP,Fan XG

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:It is important to modulate the expression of glucocorticoids receptor (GR) in tress and maintain the immunity homeostasis in sepsis process. Rhubarb have been shown to have potential effects on anti-inflammatory and immune modulation. The present study was designed to investigate the effects of rhubarb on t...

journal_title：Chinese medical journal

authors： Liu J,Li G,Chen YZ,Zhang LD,Wang T,Wen ZL,Wang L,Chen DC

更新日期：2019-05-20 00:00:00

abstract：OBJECTIVE:To study whether human umbilical cord blood CD34+ cells transduced with human aldehyde dehydrogenase class-1 (ALDH-1) and multidrug resistance gene (MDR1) have increases resistance to 4-Hydroperoxycyclo-phosphamide (4-HC) and P-glycoprotein effluxed drugs. METHODS:A bicistronic retroviral vector G1Na-ALDH1-I...

journal_title：Chinese medical journal

authors： Wang J,Chen Z,Xia X,Lu D,Xue J,Ruan C

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVE:To assess the effects of Dy-DTPA-BMA (sprodiamide) on ex-vivo MR imaging of reperfused acute myocardial infarction. METHODS:Eighteen dogs were subjected to 2-hour coronary artery occlusion followed by 24-hour reperfusion. Dysprosium-chelate (Dy-DTPA-BMA) was injected into 16 dogs. Twenty minutes before their...

journal_title：Chinese medical journal

authors： Zhao S,Revel D,Arteaga C,Canet E,Liu S,Hadour G,Forrat R,Oksendal A

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Studies on selected patients undergoing off-pump versus on-pump coronary artery bypass surgery have produced inconsistent results, especially in patients with multiple coronary artery disease. This study compared the clinical results of on-pump and off-pump coronary bypass surgery in patients with triple-ves...

journal_title：Chinese medical journal

authors： Chen X,Xu M,Shi HW,Mu XW,Chen ZQ,Qiu ZB

更新日期：2004-03-01 00:00:00