Long-term immunogenicity and efficacy of recombinant yeast derived hepatitis B vaccine for interruption of mother-infant transmission of hepatitis B virus.

abstract：OBJECTIVE:Intermediate-risk acute myeloid leukemia (IR-AML), which accounts for a substantial number of AML cases, is highly heterogeneous. We systematically summarize the latest research progress on the significance of gene mutations for prognostic stratification of IR-AML. DATA SOURCES:We conducted a systemic search...

journal_title：Chinese medical journal

authors： Wang BH,Li YH,Yu L

更新日期：2015-09-05 00:00:00

abstract：BACKGROUND:The most important objective of transplant studies in the injured spinal cord has been to provide a favorable environment for axonal growth. Moreover, the continuing discovery of new grafts is providing new potentially interesting transplant candidates. Our purpose was to observe the morphological and functi...

journal_title：Chinese medical journal

authors： Chen G,Hu YR,Wan H,Xia L,Li JH,Yang F,Qu X,Wang SG,Wang ZC

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:Hypertension is an important risk factor of cardiovascular disease and increases mortality in the elderly. However, the available medical evidences are both inconsistent and insufficient regarding establishing credible and useful blood pressure (BP) targets in the hypertensive elderly. This review summarizes ...

journal_title：Chinese medical journal

authors： Liu P,Zheng JG

更新日期：2017-08-20 00:00:00

abstract：BACKGROUND:The effects of oral contrast agents (OCAs) on dosimetry have not been studied in detail. Therefore, this study aimed to examine the influence of OCAs on dose calculation in volumetric-modulated arc therapy plans for rectal cancer. METHODS:From 2008 to 2016, computed tomography (CT) images were obtained from...

journal_title：Chinese medical journal

authors： Jing H,Tian Y,Tang Y,Wang SL,Jin J,Song YW,Liu YP,Fang H,Chen B,Qi SN,Tang Y,Lu NN,Yang Y,Li N,Li YX

更新日期：2020-09-05 00:00:00

abstract：BACKGROUND:Diffusion weighted imaging with background suppression (DWIBS) is potentially useful in detecting metastatic lymph nodes. This study aimed to evaluate the efficacy of DWIBS at 3T magnetic resonance (MR) for diagnosing metastatic lymph nodes in cervical cancer. METHODS:This retrospective study included 25 pa...

journal_title：Chinese medical journal

authors： Yu SP,He L,Liu B,Zhuang XZ,Liu MJ,Hu XS

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Survivin is an oncoprotein silenced in normal mature tissues but reactivated in serous ovarian cancer (SOC). Although transcriptional activation is assumed for its overexpression, the long 3'-untranslated region (3'-UTR) in survivin gene, which contains many alternate polyadenylation (APA) sites, implies a p...

journal_title：Chinese medical journal

authors： He XJ,Zhang Q,Ma LP,Li N,Chang XH,Zhang YJ

更新日期：2016-05-20 00:00:00

abstract：BACKGROUND:The development of new adjuvants for human use has been the focus of attention. This study's aim is to explore the possibility of using nanoparticle Ca nanoparticles (CA) as a vaccine adjuvant of anti-idiotypic antibody NP30 against schistosomiasis and its protective mechanisms. METHODS:Nanoparticle CA-NP30...

journal_title：Chinese medical journal

authors： Feng ZQ,Zhong SG,Li YH,Li YQ,Qiu ZN,Wang ZM,Li J,Dong L,Guan XH

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of propofol, midazolam and thiopental sodium on outcomes and amino acid accumulation in focal cerebral ischemia-reperfusion in rats. METHODS:Male Sprague Dawley (SD) rats were scheduled to undergo 3-hour middle cerebral artery occlusion by intraluminal suture and 24-hour reperfusio...

journal_title：Chinese medical journal

authors： Chen L,Gong Q,Xiao C

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:Chronic intermittent hypoxia (CIH) is the most important pathophysiologic feature of sleep apnea syndrome (SAS). To explore the relationship between SAS and dementia, the effects of CIH on the expression of Nip3, neuron apoptosis and beta-amyloid protein deposit in the brain cortex of the frontal lobe of mic...

journal_title：Chinese medical journal

authors： Zeng YM,Cai KJ,Chen XY,Wu MX,Lin X

更新日期：2009-01-05 00:00:00

abstract：BACKGROUND:C-arm-based flat-panel detector cone-beam computed tomography (CBCT) venography has never been used in the management of iliac vein compression syndrome (IVCS). This study aimed to determine the technical feasibility and safety of CBCT venography in the diagnosis of IVCS compared with conventional venography...

journal_title：Chinese medical journal

authors： Wang CM,Zhang WL,Li X

更新日期：2020-08-26 00:00:00

abstract：OBJECTIVE:To investigate the effect of Q-switched alexandrite laser irradiation on dermal melanocytes of nevus of Ota. METHODS:Multiple biopsies were carried out on 4 patients with nevus of Ota before and after laser irradiation. Altogether 11 samples were examined under light microscope and 14 under transmission elec...

journal_title：Chinese medical journal

authors： Lu Z,Chen J,Wang X,Fang L,Jiao S,Huang W

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Ophthalmic gel has been developed to increase the drug concentration in aqueous humor and to retard the loss of drug from the conjunctival sac. The research was to compare the drug concentration in aqueous humor of cataract patients administered 0.3% gatifloxacin ophthalmic gel with that in patients administ...

journal_title：Chinese medical journal

authors： Liu X,Wang NL,Wang YL,Ma C,Ma L,Gao LX,Huang YX,Xiong SH,Wang K

更新日期：2010-08-05 00:00:00

abstract：OBJECTIVE:To determine mutations of two common potassium channel subunit genes KCNQ1, KCNH2 causing long QT syndrome (LQTS) in the Chinese. METHODS:Thirty-one Chinese LQTS pedigrees were characterized for mutations in the two LQTS genes, KCNQ1 and KCNH2, by sequencing. RESULTS:Two novel KCNQ1 mutations, S277L in the ...

journal_title：Chinese medical journal

authors： Liu W,Hu D,Li C,Li P,Li Y,Li Z,Li L,Qin X,Dong W,Qi Y,Chen S,Wang Q

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:Recurrence or metastasis of myxomas is not rare and can lead to malignancy. We aimed to analyze the risk factors for postoperative cardiac myxoma recurrence and to summarize its clinical characteristics, treatments and classification. METHODS:The clinical data of 5 patients with recurrent cardiac myxoma wer...

journal_title：Chinese medical journal

authors： Sheng WB,Luo BE,Liu Y,Zhang H,Zou LJ,Xu ZY,Zhang HY,Ji GY

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVE:To review the recent developments in the mechanisms of glucocorticoids induced osteonecrosis of femoral head (ONFH) and introduce a new theory of ONFH. DATA SOURCES:Both Chinese- and English-language literatures were searched using MEDLINE (1997 - 2011), Pubmed (1997 - 2011) and the Index of Chinese-language...

journal_title：Chinese medical journal

authors： Tan G,Kang PD,Pei FX

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Precise evaluation of the live donor's liver is the most important factor for the donor's safety and the recipient's prognosis in living donor liver transplantation (LDLT). Our study assessed the clinical value of computer-assisted three-dimensional quantitative assessment and a surgical planning tool for do...

journal_title：Chinese medical journal

authors： Wei L,Zhu ZJ,Lü Y,Jiang WT,Gao W,Zeng ZG,Shen ZY

更新日期：2013-04-01 00:00:00

abstract：:Ninety-five patients with perforation, hemorrhage or stenosis due to duodenal ulcer were treated by extended parietal cell vagotomy. Postoperative follow-up ranged from 3.5 to 10 years (mean 6 years) in 88 patients (92%) with acute perforation (60), hemorrhage (8) and stenosis (20). There was no operative mortality. U...

journal_title：Chinese medical journal

authors： Li SY,An P,Liang ZJ,Yuan SJ,Yu J

更新日期：1992-04-01 00:00:00

abstract：OBJECTIVE:To study the relationship between cartilage end-plate calcification and intervertebral disc degeneration. METHODS:An experimental model of cervical disc degeneration in rabbits was established by resection of the cervical supraspinous and interspinous ligaments and detachment of the posterior paravertebral m...

journal_title：Chinese medical journal

authors： Peng B,Hou S,Shi Q,Jia L

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND:Embryo quality and receptivity of the endometrium are two factors that determine the results of in vitro fertilization/intra-cytoplasmic sperm injection-embryo transfer (IVF/ICSI-ET). There is no consensus of the optimal transfer strategy for normal responders or high responders. The current study aimed to f...

journal_title：Chinese medical journal

authors： Wu KL,Zhao HB,Liu H,Zhong WX,Yu GL,Chen ZJ

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Isocitrate lyase (ICL) was previously demonstrated to play a pivotal role in the intracellular metabolism of Mycobacterium tuberculosis (MTB). Presently several lines of evidence suggest that ICL from MTB (MTB-ICL) may play some roles in the interaction between MTB and host macrophage. However, there has bee...

journal_title：Chinese medical journal

authors： Li JM,Li N,Zhu DY,Wan LG,He YL,Yang C

更新日期：2008-06-20 00:00:00

abstract：BACKGROUND:An inflammatory response leading to organ dysfunction and failure continues to be a major problem after injury in many clinical conditions such as sepsis, severe burns, and trauma. It is increasingly recognized that atrial natriuretic peptide (ANP) possesses a broad range of biological activities, including ...

journal_title：Chinese medical journal

authors： Zhu YB,Zhang YB,Liu DH,Li XF,Liu AJ,Fan XM,Qiao CH,Ling F,Liu YL

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Retinol binding protein 4 (RBP4), as an adipocyte secreted cytokine, was recently found to be inversely correlated with expression of glucose transporter 4 (GLUT4) in insulin resistance (IR) state and to have an intimate relationship with IR and type 2 diabetes mellitus (T2DM). The present study aimed to eva...

journal_title：Chinese medical journal

authors： Zhang W,Xu YC,Guo FJ,Meng Y,Li ML

更新日期：2008-11-05 00:00:00

abstract：BACKGROUND:The evoked electromyography (EMG) is frequently used to identify facial nerve in order to prevent its damage during surgeries. Partial neuromuscular blockade (NMB) has been suggested to favor EMG activity and insure patients' safety. The aim of this study was to determine an adequate level of NMB corresponde...

journal_title：Chinese medical journal

authors： Cai YR,Xu J,Chen LH,Chi FL

更新日期：2009-02-05 00:00:00

abstract：OBJECTIVE:To review articles aiming to present an overview of the principles, progress, uses and limitations of laser speckle flowgraphy (LSFG) in posterior fundus circulation research. DATA SOURCES:The data used in this review was obtained mainly from the studies reported in PubMed using the key terms "laser speckle"...

journal_title：Chinese medical journal

authors： Zhang W,Kogure A,Yamamoto K,Hori S

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:To investigate whether coagulation factor VII (FVII) polymorphisms play a role in the pathogenesis of coronary artery disease (CAD) and/or myocardial infarction (MI) in a series of Hans. METHODS:The Arg(353)Gln and HVR4 polymorphisms of FVII gene were determined in 374 patients undergoing selective coronary ...

journal_title：Chinese medical journal

authors： Xu G,Jin G,Fu G,Ma J,Shi Y,Tang O,Shan J

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Epinephrine has been used as a first-choice vasopressor drug for cardiac arrest (CA) since 1974. However, the administration of epinephrine is controversial. This study aims to compare the effects of Shen-Fu injection (SFI) and epinephrine on resuscitation outcomes in a porcine model of prolonged CA. METHOD...

journal_title：Chinese medical journal

authors： Yin W,Guo Z,Li C

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:MicroRNAs (miRNAs) are highly conserved small non-coding RNAs of 18 - 25 nucleotides (nt) that mediate post-transcriptional gene regulation. Hepatitis B virus (HBV) can cause either acute or chronic hepatitis B, and is a high risk factor for liver cirrhosis and hepatocellular carcinoma. Some mammalian viruse...

journal_title：Chinese medical journal

authors： Liu Y,Zhao JJ,Wang CM,Li MY,Han P,Wang L,Cheng YQ,Zoulim F,Ma X,Xu DP

更新日期：2009-01-05 00:00:00

abstract：BACKGROUND:Epigallocatechin-3-gallate (EGCG) has exhibited antitumor properties in several types of cancers, including nasopharyngeal carcinoma (NPC), but the molecular mechanisms underlying this function remain incompletely understood. The aim of the present study was to characterize the global impact of EGCG on the e...

journal_title：Chinese medical journal

authors： Li BB,Huang GL,Li HH,Kong X,He ZW

更新日期：2017-01-05 00:00:00

abstract：BACKGROUND:Blood glucose control is closely related to type 2 diabetes mellitus (T2DM) prognosis. This multicenter study aimed to investigate blood glucose control among patients with insulin-treated T2DM in North China and explore the application value of combining an elastic network (EN) with a machine-learning algor...

journal_title：Chinese medical journal

authors： Wang J,Wang MY,Wang H,Liu HW,Lu R,Duan TQ,Li CP,Cui Z,Liu YY,Lyu YJ,Ma J

更新日期：2020-01-05 00:00:00

abstract：BACKGROUND:Serum expression of cytokines may provide information about the clinical outcome of advanced non-small cell lung cancer (NSCLC) patients. This study aimed to investigate the relationship between serum cytokine levels and the clinical outcome of erlotinib treatment in a second or third line setting in patient...

journal_title：Chinese medical journal

authors： Wang YS,Miao LY,Liu L,Cai HR,Ding JJ,Ren SX,Zhou CC,Schmid-Bindert G

更新日期：2013-10-01 00:00:00