Blood Pressure Targets in the Hypertensive Elderly.

abstract：OBJECTIVE:Renal fibrosis is the most common manifestation of chronic kidney disease (CKD). Noting that existing treatments of renal fibrosis only slow disease progression but do not cure it, there is an urgent need to identify novel therapies. Hydrogen sulfide (H2S) is a newly discovered endogenous small gas signaling ...

journal_title：Chinese medical journal

authors： Wang Y,Xing QQ,Tu JK,Tang WB,Yuan XN,Xie YY,Wang W,Peng ZZ,Huang L,Xu H,Qin J,Xiao XC,Tao LJ,Yuan QJ

更新日期：2019-12-05 00:00:00

abstract：BACKGROUND:The effects of oral contrast agents (OCAs) on dosimetry have not been studied in detail. Therefore, this study aimed to examine the influence of OCAs on dose calculation in volumetric-modulated arc therapy plans for rectal cancer. METHODS:From 2008 to 2016, computed tomography (CT) images were obtained from...

journal_title：Chinese medical journal

authors： Jing H,Tian Y,Tang Y,Wang SL,Jin J,Song YW,Liu YP,Fang H,Chen B,Qi SN,Tang Y,Lu NN,Yang Y,Li N,Li YX

更新日期：2020-09-05 00:00:00

abstract：ABSTRACT:Cerebral small vessel disease (SVD) is a common global brain disease that causes cognitive impairment, ischemic or hemorrhagic stroke, problems with mobility, and neuropsychiatric symptoms. The brain damage, seen as focal white and deep grey matter lesions on brain magnetic resonance imaging (MRI) or computed ...

journal_title：Chinese medical journal

authors： Clancy U,Appleton JP,Arteaga C,Doubal FN,Bath PM,Wardlaw JM

更新日期：2020-10-06 00:00:00

abstract：:Somatosensory evoked potentials (SEP) arising from median nerve stimulation were recorded in 102 patients with unilateral cerebral hemorrhage or infarct located in basal ganglion, internal capsule, thalamus or cerebral lobe. Of them 42 cases were followed up and reexamined with SEPs. Three types of SEPs were observed:...

journal_title：Chinese medical journal

authors： Lu ZN,Yu SZ

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Restrictive cardiomyopathy (RCM) is the least common cardiomyopathy in which the walls are rigid and the heart is restricted from stretching and filling properly. Cardiac troponin I (cTnI) mutation-caused myofibril Ca2+ hypersensitivity has been shown to be associated with impaired diastolic function. This s...

journal_title：Chinese medical journal

authors： Ding WH,Han L,Xiao YY,Mo Y,Yang J,Wang XF,Jin M

更新日期：2017-12-05 00:00:00

abstract：BACKGROUND:Now lung volume reduction surgery (LVRS) has become one of the most effective methods for the management of some cases of severe chronic obstructive pulmonary disease (COPD). We evaluated the mid-term effects of LVRS on pulmonary function in patients with severe COPD. METHODS:Ten male patients with severe C...

journal_title：Chinese medical journal

authors： Liu JM,Yang WL,Jiang GN,Ding JA,Zheng W,Liu WZ,Wang YM,Gao BL,Jiang P,Wu W,Li X,Bjorn J

更新日期：2007-04-20 00:00:00

abstract：BACKGROUND:While combined oral contraceptives (COCs) are commonly used to treat polycystic ovary syndrome (PCOS), comparative data regarding metabolic effects of different progestogens on this patient population are missing. This study aimed to compare the different effects of drospirenone (DRP)-containing COCs with cy...

journal_title：Chinese medical journal

authors： Wang QY,Song Y,Huang W,Xiao L,Wang QS,Feng GM

更新日期：2016-04-20 00:00:00

abstract：BACKGROUND:Pulmonary problems often occur in patients with early-onset scoliosis (EOS). However, lung function in patients with EOS after growing rod surgery has not been documented. The aim of this study was to investigate lung function after the treatment for EOS with growing rod and its possible correlative factors....

journal_title：Chinese medical journal

authors： Jiang Y,Zhao Y,Wang YP,Qiu GX,Weng XS,Li Y

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:To investigate the relationship between the expression and regulation of osteopontin (OPN) and urolithiasis. METHODS:Normal and stone model rats were treated with 1,25-dihydroxyvitamin D3(D3), vitamin K, testosterone or estradiol for 7 days, and the expression of osteopontin and its mRNA were detected with i...

journal_title：Chinese medical journal

authors： Chang L,Feng T,Li J,Dou C,Wei J,Guo Y

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND:Evidence has demonstrated that the distal lung, which includes airways of < 2 mm in diameter and lung parenchyma, constitutes an important component of asthma pathology. Cysteinyl leukotrienes (CysLTs) are potent proinflammatory mediators and bronchoconstrictors involved in the asthmatic process. Guidelines ...

journal_title：Chinese medical journal

authors： Gao JM,Cai F,Peng M,Ma Y,Wang B

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:Intermediate-risk acute myeloid leukemia (IR-AML), which accounts for a substantial number of AML cases, is highly heterogeneous. We systematically summarize the latest research progress on the significance of gene mutations for prognostic stratification of IR-AML. DATA SOURCES:We conducted a systemic search...

journal_title：Chinese medical journal

authors： Wang BH,Li YH,Yu L

更新日期：2015-09-05 00:00:00

abstract：BACKGROUND:Although obstructive sleep apnea (OSA) has been recognized as a major risk factor for cardiovascular complications and its clinical features are well characterized, it is difficult to replicate the OSA hypoxic model in humans. We aimed to establish an experimental rabbit model for chronic OSA and to explore ...

journal_title：Chinese medical journal

authors： Xu LF,Zhou XF,Hu K,Tang S,Luo YC,Lu W

更新日期：2017-02-20 00:00:00

abstract：BACKGROUND:Acinetobacter baumannii is one of the main gram-negative bacilli in clinical practice. Nosocomial infections caused by multi-drug resistance Acinetobacter baumannii is very difficult to treat. This study was designed to investigate the antimicrobial resistance characteristics and four resistant gene expressi...

journal_title：Chinese medical journal

authors： Shi WF,Jiang JP,Mi ZH

更新日期：2005-01-20 00:00:00

abstract：OBJECTIVES:To investigate the effect of Burn Healing Liquid (BHL) on the proliferation of keratinocytes and fibroblasts and to explore the potential effect of BHL on fibroblast contraction. METHODS:Human keratinocytes and dermal fibroblasts were cultured in media containing serial dilutions of BHL followed by cell pro...

journal_title：Chinese medical journal

authors： Su Y,Chen B,Thang PT,Hughes MA,Xu X,Cherry GW

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:Psoriasis is a chronic inflammatory skin disease, affecting about 0.6% of the Chinese population. Many patients are not well controlled by conventional treatments, thus there is need for new treatment regimens. In this study, we assessed the efficacy and safety of secukinumab in Chinese patients with moderat...

journal_title：Chinese medical journal

authors： Cai L,Zhang JZ,Yao X,Gu J,Liu QZ,Zheng M,Zhang SF,Xu JH,Li CX,Cheng H,Guo Q,Pan WL,Li SQ,Li RY,Guo ZP,Song ZQ,Li SS,Dong XQ,Wang L,Fu R,Regnault P,Charef P,Mazur R,Patekar M

更新日期：2020-11-20 00:00:00

abstract：BACKGROUND:Gingerol is the generic term for pungent constituents in ginger, which has been reported to be effective for inhibiting vomiting. We attempted to investigate the antiemetic effect of gingerol and its effective mechanism on substance P and NK(1) receptors in minks. METHODS:The antiemetic effect of gingerol w...

journal_title：Chinese medical journal

authors： Qian QH,Yue W,Chen WH,Yang ZH,Liu ZT,Wang YX

更新日期：2010-02-20 00:00:00

abstract：BACKGROUND:In-hospital medical complications are associated with poorer clinical outcomes for stroke patients after disease onset. However, few studies from China have reported the effect of these complications on the mortality of patients with acute ischemic stroke. In this prospective work, the China National Stroke ...

journal_title：Chinese medical journal

authors： Wang PL,Zhao XQ,Yang ZH,Wang AX,Wang CX,Liu LP,Wang YL,Wang XG,Ju Y,Chen SY,Chen QD,Qu H,Lu JJ,Zhang J,Ma RH,Zhang YM,Wang YJ

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Periostin originally designated osteoblast-specific factor 2 (OSF-2) is frequently found to be highly expressed in various types of human cancer cell lines in vitro and human cancer tissues in vivo. We proposed that periostin was a key factor during the process of proliferation and invasion in cancer cells. ...

journal_title：Chinese medical journal

authors： Liu C,Huang SJ,Qin ZL

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:The treatment of spinal cord injury is still a challenge. This study aimed at evaluating the therapeutical effectiveness of neurons derived form mesenchymal stem cells (MSCs) for spinal cord injury. METHODS:In this study, rhesus MSCs were isolated and induced by cryptotanshinone in vitro and then a process ...

journal_title：Chinese medical journal

authors： Deng YB,Yuan QT,Liu XG,Liu XL,Liu Y,Liu ZG,Zhang C

更新日期：2005-09-20 00:00:00

abstract：BACKGROUND:Liver cirrhosis is the fatal consequence of chronic hepatitis, making early diagnosis of liver cirrhosis critical. Liver biopsy is still the standard diagnostic method for liver cirrhosis, although its use in a broad population with alcoholism or hepatitis B virus (HBV) infection remains difficult. In this s...

journal_title：Chinese medical journal

authors： Lian JS,Liu W,Hao SR,Guo YZ,Huang HJ,Chen DY,Xie Q,Pan XP,Xu W,Yuan WX,Li LJ,Huang JR

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:With the significant improvement in the survival of patients with nasopharyngeal carcinoma (NPC) undergoing radiotherapy and the growing availability of the sophisticated imaging modalities, the number of radiation encephalopathy (RE) cases relating to NPC radiotherapy is increasing. In this study, we invest...

journal_title：Chinese medical journal

authors： Wang XL,Yin JL,Li H,Li XD,Quan JT

更新日期：2007-03-20 00:00:00

abstract：BACKGROUND:Respiratory syncytial virus (RSV) is a common pathogen in the lower respiratory tract of infants and children. Recent studies have shown that in adults, especially in the elderly population who have relatively weak immunity, lower respiratory tract infection is not uncommon. RSV was detected in 22% hospitali...

journal_title：Chinese medical journal

authors： Li W,Shen HH

更新日期：2007-01-05 00:00:00

abstract：:A case of cutaneous Rosai-Dorfman disease (CRDD) presenting as a granulomatous rosacea-like rashs was reported. A 45-year-old Chinese woman presented with a 1-month history of a widespread nonpruiginous papulonodular eruption. The rash had begun on her face and rapidly progressed to involve the neck and extremities. S...

journal_title：Chinese medical journal

authors： Shi XY,Ma DL,Fang K

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:We conducted a prospective, multicenter investigation of incidence, management and outcome of neonatal acute respiratory disorders (NARD), and evaluated related perinatal risk factors and efficacy of respiratory therapies in neonatal intensive care units (NICUs) in a Chinese neonatal network. METHODS:Data w...

journal_title：Chinese medical journal

authors： Qian LL,Liu CQ,Guo YX,Jiang YJ,Ni LM,Xia SW,Liu XH,Zhuang WZ,Xiao ZH,Wang SN,Zhou XY,Sun B,Chinese Collaborative Study Group for Neonatal Respiratory Diseases.

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:At the end of 2005, 650,000 people lived with human immunodeficiency virus type-1 (HIV-1) in China, of whom 75 000 were AIDS patients. Many AIDS patients received highly active antiretroviral therapy (HAART) supported by the "China CARES" program but the immune responses of HAART were seldom reported. This s...

journal_title：Chinese medical journal

authors： Zhang ZN,Shang H,Jiang YJ,Liu J,Dai D,Diao YY,Geng WQ,Jin X,Wang YN

更新日期：2006-12-05 00:00:00

abstract：:The effects of hypoxic endothelial cell conditioned medium (HECCM) on proliferation and collagen synthesis of cultured porcine pulmonary arterial smooth muscle cells (PASMCs) were studied by 3H-thymidine (3H-TdR) and 3H-proline incorporations, image analysis for determination of DNA content and colorimetric assay usin...

journal_title：Chinese medical journal

authors： Sun B,Yuan Y,Zhang W,Che D

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:Jaw osteonecrosis possibly associated with the administration of bisphosphonates is expected to be treated with a non-pharmacologic approach. This study aimed to determine whether noninvasive, mechanically mediated vibration would inhibit the decline in bone mineral density (BMD) that follows menopause, enha...

journal_title：Chinese medical journal

authors： Ruan XY,Jin FY,Liu YL,Peng ZL,Sun YG

更新日期：2008-07-05 00:00:00

abstract：BACKGROUND:Thoracic endovascular aortic repair (TEVAR) is an emerging treatment modality, which has been rapidly embraced by clinicians treating thoracic aortic disease. However, the clinical manifestations of systemic inflammatory response after TEVAR as post-implantation syndrome (PIS) resemble the perioperative infe...

journal_title：Chinese medical journal

authors： Xue L,Luo S,Luo J,Liu Z,Gu M,Kang H,Yang F,Nie B,Liu Y,Huang W,Xie N,He P,Dong H,Ni Z,Fan R,Chen J

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Generalized glucocorticoid resistance syndrome is a rare familial or sporadic condition characterized by generalized, partial, target-tissue insensitivity to glucocorticoids. This syndrome is partially caused by mutations in the human glucocorticoid receptor (hGR) gene. The clinical spectrum of generalized g...

journal_title：Chinese medical journal

authors： Zhu HJ,Dai YF,Wang O,Li M,Lu L,Zhao WG,Xing XP,Pan H,Li NS,Gong FY

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Prediabetes is an early stage of β-cell dysfunction presenting as insulin resistance. Evidences suggest that endoplasmic reticulum (ER) stress is involved in the pathogenesis of type 2 diabetes mellitus and prediabetes. In a Chinese population with prediabetes, we investigated single nucleotide polymorphisms...

journal_title：Chinese medical journal

authors： Feng N,Ma X,Wei X,Zhang J,Dong A,Jin M,Zhang H,Guo X

更新日期：2014-01-01 00:00:00