Mutation in the leucine-rich repeat of platelet glycoprotein Ib alpha results in defects in its interaction with immobilized von Willebrand factor under flow.

abstract：:This review summarizes recent evidences regarding the potential influences of epidural labor analgesia (ELA) on the outcomes of neonates and children. Terms and relevant words including "ELA," "ELA and neonatal outcomes," "ELA and children's development," and "ELA and children's neurocognitive development" were used t...

journal_title：Chinese medical journal

authors： Liu ZH,Wang DX

更新日期：2020-10-05 00:00:00

abstract：BACKGROUND:Magnetic resonance imaging (MRI) is commonly utilized as part of the diagnostic workup for the clinical diagnosis of glioblastoma multiforme (GBM), further guiding the clinical treatment of this aggressive cancer. Recent research has shown that microRNAs (miRNAs) may act as oncogenes, or in some cases, tumor...

journal_title：Chinese medical journal

authors： Li WB,Chen HY,Zhang W,Yan W,Shi R,Li SW,Jiang T

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:To determine the relationship between remodeling and dysfunction of left ventricle (LV) and the expression of the angiotensin II AT1 receptor mRNA after myocardial infarction (MI) in rats. METHODS:Nine MI rats (Group A) and 8 sham-operated rats (Group B) were studied by both Doppler echocardiography and Dot ...

journal_title：Chinese medical journal

authors： Zhang G,Yang Y,Pu S,Shen X,Peng T,Chen H

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:Receptor activator of nuclear factor kappa B (NF-κB) ligand (RANKL) and osteoprotegerin (OPG) have been recently shown to play important roles in bone resorption. The aim of this study was to investigate the possible association between the expression of bone resorption regulators (RANKL and OPG) and inflamm...

journal_title：Chinese medical journal

authors： Fan R,Sun B,Zhang CF,Lü YL,Xuan W,Wang QQ,Yin XZ

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:A practical problem impeding clinical translation is the limited bone formation seen in artificial bone grafts. Low-pressure/vacuum seeding and dynamic culturing in bioreactors have led to a greater penetration into the scaffolds, enhanced production of bone marrow cells, and improved tissue-engineered bone ...

journal_title：Chinese medical journal

authors： Wang J,Wang J,Yoshinori A,Paul F,Shen H,Chen J,Sotome S,Liu Z,Shinomiya K

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Fluid dynamic mechanisms attributed to coronary bifurcation lesions remain a subject of study. The present study aimed at investigating the hemodynamic change of wall shear stress (WSS) in patients with coronary bifurcation lesions treated by double kissing (DK) crush or one-stent with final kissing balloon ...

journal_title：Chinese medical journal

authors： Chen SL,Kan J,Zhang JJ,Hu ZY,Xu T

更新日期：2012-05-01 00:00:00

abstract：:131 cases of epidemic hepatitis from two villages in Xinjiang, were admitted to the provisional infectious diseases hospital from February to April 1987. In 125 (95%) patients neither anti-HAV IgM nor anti-HBc IgM were positive. 118 (90%) were drinking water from a local stream of the Hotan River. The study was conduc...

journal_title：Chinese medical journal

authors： Wang XC,Liu XM,Tan CZ,Liu R,Luo SL,Yue XH,Qin F,Bu ZR,Tian X,Song DY

更新日期：1990-11-01 00:00:00

abstract：:Lectin binding patterns in psoriasis, lichen planus and seborrheic keratosis lesions were studied using 14 different biotinyl lectins and avidin-horseradish peroxidase. Compared with normal epidermis, there were significant quantitative and qualitative differences, some of which were characteristic. ...

journal_title：Chinese medical journal

authors： Gao MY,Lin XR,Miao Q

更新日期：1992-12-01 00:00:00

abstract：BACKGROUND:Stenting a bifurcation lesion is technically challenging. No study has reported the clinical outcome of a dedicated bifurcation stent in China. We aimed to analyze the safety and clinical outcome of a novel side branch ostial stent (BIGUARD) stent in treating coronary bifurcation lesions. METHODS:Forty-seve...

journal_title：Chinese medical journal

authors： Chen SL,Zhang JJ,Ye F

更新日期：2009-09-20 00:00:00

abstract：BACKGROUND:Insulin-like growth factor-II mRNA-binding protein 3 (IMP3) is a newly identified mRNA-binding protein that is involved in embryogenesis and carcinogenesis of some malignant tumors. The aim of this study was to detect the expression of IMP3 protein in gastric adenocarcinoma (GAC) and the correlation with cli...

journal_title：Chinese medical journal

authors： Wang L,Li HG,Xia ZS,Lü J,Peng TS

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Our previous studies have shown that both apoptosis and necrosis are involved in hair cell (HC) pathogenesis in aging cochleae. To better understand the biological mechanisms responsible for the regulation of HC death, we examined the activity of succinate dehydrogenase (SDH), a mitochondrial bioenergetic en...

journal_title：Chinese medical journal

authors： Yang WP,Hu BH,Sun JH,Zhai SQ,Henderson D

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Some individuals have multiple renal arteries. Severe stenosis in one of the arteries may cause refractory hypertension. The detection of stenosis within one of the multiple renal arteries usually required invasive procedures, such as computed tomographic angiography (CTA) and magnetic resonance angiography ...

journal_title：Chinese medical journal

authors： Qin W,Zhang X,Yang M,Zhong XH,Zhao MH

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Diffusion tensor imaging (DTI) permits quantitative examination within the pyramidal tract (PT) by measuring fractional anisotropy (FA). To the best of our knowledge, the inter-variability measures of FA along the PT remain unexplained. A clear understanding of these reference values would help radiologists ...

journal_title：Chinese medical journal

authors： Roldan-Valadez E,Rios-Piedra E,Favila R,Alcauter S,Rios C

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:T8590C polymorphism of CYP4A11 has been associated with hypertension, though with conflicting results. The aim of this study was to quantitatively summarize the evidence for CYP4A11 T8590C polymorphism and hypertension risk. METHODS:Electronic search of PubMed and the Chinese Biomedicine database was conduc...

journal_title：Chinese medical journal

authors： Jiang Y,Hou J,Zhang Q,Tang W,Luo Y

更新日期：2014-01-01 00:00:00

abstract：:T cell subsets in peripheral blood were phenotyped in 56 patients with different stages of Schistosomiasis japonica, including 17 with acute, 14 with chronic and 25 with advanced infection. The activity of interleukin-1 (IL-1) produced by peripheral blood mononuclear cells (PBMC) induced by lipopolysaccharide (LPS) in...

journal_title：Chinese medical journal

authors： Li ZJ,Yang Q,Yang YX,Zeng LL,Li SL,Dai JZ,Wang HC,Luo DD,Wang XH

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND:There are no clear guidelines on implant removal. Few have assessed the long-term outcomes of patients with implants left in-situ, or removed. Therefore, removal of implants after fracture fixation remains controversial. METHODS:In this retrospective study, we reviewed 53 patients with implant for fracture ...

journal_title：Chinese medical journal

authors： Leung AH,Shen J,Leung AH,Hung YW,Mok AH,Cheung WH,Leung KS

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Matrix metalloproteinase (MMP)-2 plays an important role in the remodeling of left ventricles (LVs) and right ventricles (RVs). We investigated the differences of MMP-2 expression between LV and RV in response to nandrolone decanoate (ND), swimming training (ST), and combined ND and ST (NS) in mice, based on...

journal_title：Chinese medical journal

authors： Bai Y,Shi XB,Zhang YQ,Wang YL,Liu XY,Esteve-Pastor MA

更新日期：2018-01-20 00:00:00

abstract：BACKGROUND:Frozen-thawed embryo transfer (FET) is the most common way to prevent serious late ovarian hyperstimulation syndrome and increase the cumulative pregnancy rate. We evaluated the effectiveness of an FET program for improving the embryo implantation and clinical pregnancy rates, and ultimate embryo utilization...

journal_title：Chinese medical journal

authors： Zhou F,Lin XN,Tong XM,Li C,Liu L,Jin XY,Zhu HY,Zhang SY

更新日期：2009-09-05 00:00:00

abstract：BACKGROUND:Extracellular matrix (ECM) orchestrates cell behaviour including growth, death, apoptosis, adhesion, migration, and invasion by activating several signalling pathways. Certain components of ECM, such as integrins, may act as receptors or co-receptors of enterovirus. ECM-activated gene expressions in myocardi...

journal_title：Chinese medical journal

authors： Zhang ZC,Li SJ,Yang YZ,Chen RZ,Ge JB,Chen HZ

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Ilexonin A (IA), purified from the Chinese herbal medicine Maodongqing (Ilex pubescens Hook, et Arn) has been commonly used in south China to treat thrombotic disorders. In this study, we aimed to study the inhibiting effects and mechanism of IA on von Willebrand factor (vWF)-dependent high shear-induced pla...

journal_title：Chinese medical journal

authors： Li M,Wu WK,Liu L,Liao FL,Shinohara Y,Handa S,Goto S

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:Human urotensin II (UII) is the most potent mammalian vasoconstrictor identified so far. Our previous study showed that UII is a potent mitogen of airway smooth muscle cells (ASMC) inducing ASMC proliferation in a dose-dependent manner. The signal transduction pathway of UII mitogenic effect remains to be cl...

journal_title：Chinese medical journal

authors： Chen YH,Zhao MW,Yao WZ,Pang YZ,Tang CS

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Recently, conservative surgery is acceptable in young patients with borderline ovarian tumor and ovarian cancer. The preservation of these patients' future fertility has been the focus of recent interest. This study aimed to observe the effect of gonadotropin-releasing hormone agonists (GnRHa) cotreatment du...

journal_title：Chinese medical journal

authors： Zhu HL,Wang Y,Li XP,Wang CH,Wang Y,Cui H,Wang JL,Wei LH

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Now lung volume reduction surgery (LVRS) has become one of the most effective methods for the management of some cases of severe chronic obstructive pulmonary disease (COPD). We evaluated the mid-term effects of LVRS on pulmonary function in patients with severe COPD. METHODS:Ten male patients with severe C...

journal_title：Chinese medical journal

authors： Liu JM,Yang WL,Jiang GN,Ding JA,Zheng W,Liu WZ,Wang YM,Gao BL,Jiang P,Wu W,Li X,Bjorn J

更新日期：2007-04-20 00:00:00

abstract：BACKGROUND:The continual and rapid development of techniques which are used for diagnosis and treatment makes management of colorectal cancer more difficult depending on single discipline. Colorectal cancer multidisciplinary team (MDT) working model is recommended by UK and other countries, but there is little informat...

journal_title：Chinese medical journal

authors： Ye YJ,Shen ZL,Sun XT,Wang ZF,Shen DH,Liu HJ,Zhang WL,Chen YL,Zhou J,Poston GJ,Wang S

更新日期：2012-01-01 00:00:00

abstract：:Patients whose routine MRI were negative but were clinically highly suspected of having intra-cranial or intra-spinal canal space-occupying lesions, and those whose routine MRI were positive but presented difficulties in defining the contour or the nature of the lesion, or difficulty in distinguishing the lesion from ...

journal_title：Chinese medical journal

authors： Shen TZ,Mei H,Huang XL,Chen XR

更新日期：1991-04-01 00:00:00

abstract：BACKGROUND:Prediabetes is an early stage of β-cell dysfunction presenting as insulin resistance. Evidences suggest that endoplasmic reticulum (ER) stress is involved in the pathogenesis of type 2 diabetes mellitus and prediabetes. In a Chinese population with prediabetes, we investigated single nucleotide polymorphisms...

journal_title：Chinese medical journal

authors： Feng N,Ma X,Wei X,Zhang J,Dong A,Jin M,Zhang H,Guo X

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Early diagnosis and accurate staging are important to improve the cure rate and prognosis for pancreatic cancer. This study was performed to develop an automatic and accurate imaging processing technique system, allowing this system to read computed tomography (CT) images correctly and make diagnosis of panc...

journal_title：Chinese medical journal

authors： Liu SL,Li S,Guo YT,Zhou YP,Zhang ZD,Li S,Lu Y

更新日期：2019-12-05 00:00:00

abstract：BACKGROUND:CD4(+)CD25(+) regulatory T cells (Tregs) mediate immune suppression through cell-cell contact with surface molecules, particularly cytotoxic T lymphocyte-associated antigen 4 (CTLA-4), glucocorticoid-induced tumor necrosis factor receptor family-related protein (GITR), and transforming growth factor beta (TG...

journal_title：Chinese medical journal

authors： Zhang Q,Qian FH,Liu H,Zhou LF,Huang M,Zhang XL,Yin KS

更新日期：2008-02-05 00:00:00

abstract：OBJECTIVE:To explore the methods of lens-sparing (without lensectomy), non-silicone oil tamponade and no scleral buckling for treatment of early giant retinal tears. METHODS:Thirteen cases of early retinal detachment of proliferative vitreoretinopathy (PVR) grade C2-D1, with giant tear extending from 135 degrees to 27...

journal_title：Chinese medical journal

authors： Xu X,Zhang X,Wu N,Ho PC

更新日期：1999-03-01 00:00:00

abstract：OBJECTIVES:To assess the feasibility and efficacy of eliciting leukemia-specific T-cell responses in syngeneic mice in vitro and in vivo using dendritic cells (DCs) pulsed with total RNA from leukemia cells. METHODS:DCs generated from bone marrow culture in vitro in the presence of combined cytokines were pulsed with ...

journal_title：Chinese medical journal

authors： Li M,You S,Ge W,Ma S,Ma N,Zhao C

更新日期：2003-11-01 00:00:00