Changes of T cell subsets in peripheral blood of patients with Schistosomiasis japonica and their relation to interleukin-1.

Abstract:

:T cell subsets in peripheral blood were phenotyped in 56 patients with different stages of Schistosomiasis japonica, including 17 with acute, 14 with chronic and 25 with advanced infection. The activity of interleukin-1 (IL-1) produced by peripheral blood mononuclear cells (PBMC) induced by lipopolysaccharide (LPS) in vitro was simultaneously detected in these three groups of patients. It was found that the percentages of CD3+ (total T cell), CD4+ (helper/inducer T cell) and CD8+ (suppressor/cytotoxic T cell) T cell and the level of IL-1 were significantly increased in the group of acute Schistosomiasis japonica. In the groups of chronic and advanced Schistosomiasis japonica, the proportion of CD3+ T cell, the ratio of CD3+/CD4+ and the level of IL-1 were remarkably reduced, and the percentage of CD8+ T cell was increased. The rate of CD4+ T cell was obviously decreased in cases patients with advanced Schistosomiasis japonica. The percentage of CD4+ T cell was positively correlated to the level of IL-1 in the three groups of patients. These results indicate that T cell subsets and IL-1 may play an important role in the immunoregulation of Schistosomiasis japonica.

journal_name

Chin Med J (Engl)

journal_title

Chinese medical journal

authors

Li ZJ,Yang Q,Yang YX,Zeng LL,Li SL,Dai JZ,Wang HC,Luo DD,Wang XH

subject

Has Abstract

pub_date

1993-03-01 00:00:00

pages

175-8

issue

3

eissn

0366-6999

issn

2542-5641

journal_volume

106

pub_type

杂志文章
  • Na (+) /Ca (2+) Exchanger 3 is Downregulated in the Hippocampus and Cerebrocortex of Rats with Hyperthermia-induced Convulsion.

    abstract:BACKGROUND:Na + /Ca 2+ exchanger (NCX) plays a crucial role in pentylenetetrazol-induced convulsion. However, it is unclear whether NCX is critically involved in hyperthermia-induced convulsion. In this study, we examined the potential changes in NCX3 in the hippocampus and cerebrocortex of rats with hyperthermia-induc...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.4103/0366-6999.169103

    authors: Sun D,Xiao JH,Bai Y,Chen MS,Hu JS,Wu GF,Mao B,Wu SH,Hu Y

    更新日期:2015-11-20 00:00:00

  • Efficacy and Safety of Medium-to-long-term Use of Tolterodine Extended Release with or without Tamsulosin in Patients with Benign Prostate Hyperplasia and Larger Prostate Size: A Double-blind, Placebo-controlled, Randomized Clinical Trial.

    abstract:BACKGROUND:The medium-to-long-term use of antimuscarinics alone or in combination with an α-blocker in men with an enlarged prostate is still controversial. This double-blind, placebo-controlled, randomized clinical trial aimed to investigate the efficacy and safety of medium-to-long-term use of tolterodine extended re...

    journal_title:Chinese medical journal

    pub_type: 杂志文章,随机对照试验

    doi:10.4103/0366-6999.195461

    authors: Cai JL,Zhou Z,Yang Y,Yan YF,Jing S,Na YQ

    更新日期:2016-12-20 00:00:00

  • Telomerase activity in urine in diagnosis and recurrence surveillance of urothelial carcinoma.

    abstract:OBJECTIVE:To investigate the significance of telomerase activity in urine in the diagnosis and recurrence surveillance of urothelial carcinoma. METHODS:Telomerase activity in urine of 54 cases of urothelial carcinoma (urothelial carcinoma group) was estimated by polymerase chain reaction-enzyme-linked immunosorbent as...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Li Z,Kong C,Wang P,Liu X,Liu T

    更新日期:2002-11-01 00:00:00

  • A multi-center investigation of breast-conserving surgery based on data from the Chinese Society of Breast Surgery (CSBrS-005).

    abstract:BACKGROUND:Although breast-conserving surgery is one of the standard treatments for breast cancer, few studies have assessed its recent implementation in China. We aimed to clarify the current real-world status of breast-conserving surgery in China. METHODS:This cross-sectional survey relied on data collected by the C...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.1097/CM9.0000000000001152

    authors: Yu LX,Shi P,Tian XS,Yu ZG,Chinese Society of Breast Surgery.

    更新日期:2020-11-20 00:00:00

  • Fatigue cyclic loading test of an auro-galvanoforming ceramic bridge.

    abstract:BACKGROUND:In dental clinics, dentition defects are commonly restored with conventional porcelain-fused-to-metal fixed bridges. However, Ni-Cr alloy ceramic fixed bridges are known to have several drawbacks such as marginal coloration of the neck, low casting precision and, most seriously, poor biocompatibility. These ...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Zhang XH,Sun F,Wang H,Xu MQ

    更新日期:2008-10-05 00:00:00

  • Glucokinase gene variants in Chinese subjects with the common form of NIDDM.

    abstract:OBJECTIVE:To determine whether mutation of the coding or junction region of glucokinase gene (GCK) is also the pathogenic cause of the common form of non-insulin-dependent diabetes mellitus (NIDDM) in Chinese. METHODS:Single strand conformation polymorphism (SSCP) analysis was performed after the 12 exons and junction...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Xiang K,Wu S,Zheng T,Sun D,Wang Y,Pu L

    更新日期:1996-11-01 00:00:00

  • CT features of colloid carcinomas of the pancreas.

    abstract:BACKGROUND:Colloid carcinomas of the pancreas have better prognosis than ordinary ductal adenocarcinoma, and preoperative distinction of colloid carcinoma from other pancreatic tumors is valuable for patient therapeutic planning and prognosis assessment. However, data about CT features of colloid carcinoma are very lim...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Ren FY,Shao CW,Zuo CJ,Lu JP

    更新日期:2010-05-20 00:00:00

  • Role of Lactobacillus in the prevention of Clostridium difficile-associated diarrhea: a meta-analysis of randomized controlled trials.

    abstract:BACKGROUND:Clostridium difficile-associated diarrhea (CDAD) is a major public health problem because of significant morbidity and mortality, and many clinicians pay attention to Lactobacillus as a potentially effective treatment. The purpose of this meta-analysis was to evaluate the efficacy of Lactobacillus in the pre...

    journal_title:Chinese medical journal

    pub_type: 杂志文章,meta分析

    doi:

    authors: Wu ZJ,DU X,Zheng J

    更新日期:2013-11-01 00:00:00

  • A family with Fabry's disease. Ocular manifestations and transmission electron microscopic examination of a skin lesion biopsy.

    abstract::A family with Fabry's disease including 2 hemizygotes and 3 heterozygotes is reported. The ocular manifestations include tortuosity of conjunctival vessels, Fabry's deposits underlying the anterior capsule of the lens and the whorl-like corneal dystrophy. Foam cells or mulberry cells in the urinary sediment and varyin...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Bao LL,Guo LL,Li SN,Xiao J,Yang JS,Bai LR,Ye PM,Guo ZT,Liu DW

    更新日期:1990-02-01 00:00:00

  • Clinical Study on 136 Children with Sudden Sensorineural Hearing Loss.

    abstract:BACKGROUND:The prevalence of sudden sensorineural hearing loss in children (CSSNHL) is consistently increasing. However, the pathology and prognosis of CSSNHL are still poorly understood. This retrospective study evaluated clinical characteristics and possible associated factors of CSSNHL. METHODS:One hundred and thir...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.4103/0366-6999.179791

    authors: Li FJ,Wang DY,Wang HY,Wang L,Yang FB,Lan L,Guan J,Yin ZF,Rosenhall U,Yu L,Hellstrom S,Xue XJ,Duan ML,Wang QJ

    更新日期:2016-04-20 00:00:00

  • Lactadherin and procoagulant activities of red blood cells in cyclosporine induced thrombosis.

    abstract:BACKGROUND:The side effects of cyclosporine therapy include thromboembolic complications. However, the mechanisms underlying the hypercoagulable state induced by cyclosporine are not fully understood. Cyclosporine binds to red blood cells (RBCs) with a high affinity in circulation and alters the membranes of RBCs. Ther...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Zheng YN,Yu HJ,Hou JX,Lu CF,Zhou J

    更新日期:2009-07-20 00:00:00

  • Lumbar pedicle cortical bone trajectory screw.

    abstract:OBJECTIVE:The purpose of this study was to demonstrate the lumbar pedicle cortical bone trajectory (CBT) screw fixation technique, a new fixation technique for lumbar surgery. DATA SOURCES:The data analyzed in this review are mainly from articles reported in PubMed published from 1994 to 2014. STUDY SELECTION:Origina...

    journal_title:Chinese medical journal

    pub_type: 杂志文章,评审

    doi:

    authors: Song T,Hsu WK,Ye T

    更新日期:2014-01-01 00:00:00

  • Anti-tumor effects of polybutylcyanoacrylate nanoparticles of diallyl trisulfide on orthotopic transplantation tumor model of hepatocellular carcinoma in BALB/c nude mice.

    abstract:BACKGROUND:Hepatocellular carcinoma (HCC) ranked the second among the causes of cancer mortality in China since the 1990s. Up to now, medication still plays an important role in the treatment of HCC. The therapies based on the allicin as a potential chemopreventive analog although is in its infancy at the present time,...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Zhang ZM,Yang XY,Deng SH,Xu W,Gao HQ

    更新日期:2007-08-05 00:00:00

  • Complications of laparoscopic cholecystectomy in China: an analysis of 39,238 cases.

    abstract:OBJECTIVE:To investigate the complications of laparoscopic cholecystectomy in China. METHODS:All Chinese articles about laparoscopic cholecystectomy published between April 1994 and November 1995 were identified through CMCC (Chinese Medical Computerized Contents). From more than 600 titles, 105 articles were screened...

    journal_title:Chinese medical journal

    pub_type: 杂志文章,评审

    doi:

    authors: Huang X,Feng Y,Huang Z

    更新日期:1997-09-01 00:00:00

  • Further characterization of Chinese Leishmania isolates by isoenzyme electrophoresis.

    abstract::Ten Chinese Leishmania isolates from different endemic areas and hosts are characterized by isoenzyme electrophoresis for 9 enzymes. Seven were isolated from visceral leishmaniasis patients, one from an infected dog, one from a sandfly and one from a naturally infected racoon dog. Eight of the 10 isolates were indisti...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Xu ZB,Liu ZT,Long JY,Chai JJ,Chen WK

    更新日期:1989-09-01 00:00:00

  • Efficacy of Different Treatment Regimens for Antiphospholipid Syndrome-related Recurrent Spontaneous Abortion.

    abstract:BACKGROUND:Antiphospholipid syndrome (APS)-related immune factors are considered as an important cause of recurrent spontaneous abortion (RSA). Anticoagulant and anti-inflammatory treatments are believed to effectively improve adverse pregnancy outcomes by affecting the abnormal autoimmune response of the maternal-feta...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.4103/0366-6999.207471

    authors: Ye SL,Gu XK,Tao LY,Cong JM,Wang YQ

    更新日期:2017-06-20 00:00:00

  • Cross-sectional study of congenital heart disease among Tibetan children aged from 4 to 18 years at different altitudes in Qinghai Province.

    abstract:BACKGROUND:Congenital heart disease (CHD) is a common heart condition which does considerable harm to the health of children and adolescents. CHD epidemiological characteristics of Tibetan children whose ages ranged from 4 to 18 years were investigated in Qinghai Province. METHODS:A total of 32 578 Tibetan children, l...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Chen QH,Wang XQ,Qi SG

    更新日期:2008-12-20 00:00:00

  • Value of polymerase chain reaction assay in diagnosis of intestinal tuberculosis and differentiation from Crohn's disease.

    abstract::It is difficult to make a precise diagnosis of intestinal tuberculosis and to differentiate it from Crohn's disease. For evaluating Polymerase Chain Reaction (PCR) assay in these two aspects, 36 specimens of intestinal tuberculosis from surgical resections and endoscopic biopsies and 26 Crohn's disease samples were su...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Gan H,Ouyang Q,Bu H,Li S,Chen D,Li G,Yang X

    更新日期:1995-03-01 00:00:00

  • Effect of angiotensin II receptor blocker on glucose-induced mRNA expressions of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in rat mesangial cells.

    abstract:BACKGROUND:The decreased degradation of extra-cellular matrix proteins plays an important role in the onset of diabetic nephropathy. Matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of metalloproteinase-1 (TIMP-1), which are members of the matrix metalloproteinase family, are associated with this process. Angiot...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Ding HL,Guo Y,Xu MT,Li HY,Fu ZZ

    更新日期:2007-11-05 00:00:00

  • Gene expression profiles of ERCC1, TYMS, RRM1, TUBB3 and EGFR in tumor tissue from non-small cell lung cancer patients.

    abstract:BACKGROUND:Personalized medicine becomes essential in lung cancer treatment, however lung-cancer-related gene expression profiles in Chinese patients remain unknown. In this study, the correlation of gene expression profiles and clinical characteristics in non-small-cell lung cancer (NSCLC) was investigated. METHODS:S...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Yu D,Li J,Han Y,Liu S,Xiao N,Li Y,Sun X,Liu Z

    更新日期:2014-01-01 00:00:00

  • Angiotensin-converting enzyme gene I/D genotype affected metoprolol-induced reduction in 24-hour average heart rate.

    abstract:BACKGROUND:Genetic factors can influence antihypertensive response to metoprolol, and many studies focused on the relationship between the genotype in beta1-adrenergic receptor and blood pressure (BP), little was known about the association of angiotensin-converting enzyme (ACE) genotype with the therapeutic result of ...

    journal_title:Chinese medical journal

    pub_type: 临床试验,杂志文章

    doi:

    authors: Liu LW,Liu H,Chen GL,Huang YL,Han LL,Xu ZM,Jiang XJ,Li YS

    更新日期:2010-06-01 00:00:00

  • Evaluation of visual functional and morphology change in young patients with idiopathic choroidal neovascularization.

    abstract:BACKGROUND:Idiopathic choroidal neovascularization (ICNV) is an uncommon disorder affecting primarily individuals younger than the age of 50 years. In CNV patients, no apparent cause can be determined. This study aimed to evaluate the functional and morphological change of the retina with ICNV in young adults. METHODS...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Wang WQ,Liu HY,Lu FQ,Hu WT,Gong YY,Wu Y,Xu S,Wang WJ,Xu X,Wang FH,Sun XD

    更新日期:2011-06-01 00:00:00

  • Effect of in-hospital medical complications on case fatality post-acute ischemic stroke: data from the China National Stroke Registry.

    abstract:BACKGROUND:In-hospital medical complications are associated with poorer clinical outcomes for stroke patients after disease onset. However, few studies from China have reported the effect of these complications on the mortality of patients with acute ischemic stroke. In this prospective work, the China National Stroke ...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Wang PL,Zhao XQ,Yang ZH,Wang AX,Wang CX,Liu LP,Wang YL,Wang XG,Ju Y,Chen SY,Chen QD,Qu H,Lu JJ,Zhang J,Ma RH,Zhang YM,Wang YJ

    更新日期:2012-07-01 00:00:00

  • Association of defective HLA-I expression with antigen processing machinery and their association with clinicopathological characteristics in Kazak patients with esophageal cancer.

    abstract:BACKGROUND:It has been confirmed that defective expression of human leukocyte antigen class I (HLA-I) molecules can contribute to the immune evasion of cancer cells in some types of cancer. The aim of this study was to examine the expression of HLA class I antigen and the antigen-processing machinery (APM) components i...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Ayshamgul H,Ma H,Ilyar S,Zhang LW,Abulizi A

    更新日期:2011-02-01 00:00:00

  • Evidence of compromised circulation in the pathogenesis of optic nerve damage in chronic glaucomatous rabbit.

    abstract::The protective effect of improving the microcirculation on the retinal ganglion cells (RGC) and the ultrastructure of the optic nerve after intravenous (i.v.) use of Salviae miltiorrhiza (SMR) was studied in a chronic intraocular hypertension model in 36 rabbits. These rabbits were treated with topical 0.5% timolol, o...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Zhu MD,Cai FY

    更新日期:1993-12-01 00:00:00

  • Myoglobin over-expression attenuates angiogenic response in hindlimb ischemia in mice.

    abstract:BACKGROUND:Myoglobin is expressed exclusively in striated skeletal muscles and has been implicated in nitric oxide scavenging. Accumulating data suggest a critical role for nitric oxide in both the endogenous and therapeutic angiogenic response to ischemia. A clear role for myoglobin in ischemic skeletal muscle is unce...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Yang YG,Guan H,Liu CW,Li YJ

    更新日期:2009-05-05 00:00:00

  • Volatile anesthetics inhibit the activity of calmodulin by interacting with its hydrophobic site.

    abstract:BACKGROUND:Volatile anesthetics (VAs) may affect varied and complex physiology processes by manipulating Ca(2+)-calmodulin (CaM). However, the detailed mechanism about the action of VAs on CaM has not been elucidated. This study was undertaken to examine the effects of VAs on the conformational change, hydrophobic site...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Zhou MM,Xia HM,Liu J,Xu YN,Xin NX,Zhang SH

    更新日期:2012-09-01 00:00:00

  • Incubation and application of transgenic green fluorescent nude mice in visualization studies on glioma tissue remodeling.

    abstract:BACKGROUND:The primary reasons for local recurrence and therapeutic failure in the treatment of malignant gliomas are the invasion and interactions of tumor cells with surrounding normal brain cells. However, these tumor cells are hard to be visualized directly in histopathological preparations, or in experimental glio...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Dong J,Dai XL,Lu ZH,Fei XF,Chen H,Zhang QB,Zhao YD,Wang ZM,Wang AD,Lan Q,Huang Q

    更新日期:2012-12-01 00:00:00

  • HLA-DQA1, -DQB1 polymorphism distribution in Chinese women with pregnancy induced hypertension in Shanghai area.

    abstract:OBJECTIVE:To explore the association of human leukocyte antigen (HLA) with pregnancy induced hypertension (PIH). METHODS:We oligotyped HLA-DQA1, -DQB1 locus of 30 Chinese PIH families and 14 control families in Shanghai area by polymerase chain reaction-sequence specific oligonucleotide (PCR-SSO) hybridization method ...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Mao Y,Zhang Z,Fan L,Wu Q,Jiang L,Yang J,Yao F

    更新日期:1998-02-01 00:00:00

  • Long-term follow-up study of 72 patients with transient ischemic attacks.

    abstract:OBJECTIVE:To observe the long-term follow-up of 72 patients with transient ischemic attack (TIA) and evaluate the clinical significance of neurovascular surgical indication. METHODS:Seventy-two patients with TIA collected from years 1959 to 1977 were followed up by means of face-to-face communication with the patients...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Gong T,Wang X

    更新日期:2001-12-01 00:00:00