The signal transduction pathway in the proliferation of airway smooth muscle cells induced by urotensin II.

abstract：BACKGROUND:Paraquat (PQ; 1, 1'-dimethyl-4, 4'-bipyridinium), a widely used herbicide that is structurally similar to the known dopaminergic neurotoxicant MPTP (1-methyl-1, 2, 3, 6-tetrahydropyridine), has been suggested as a potential etiologic factor for the development of Parkinson's disease (PD). Aging is an accepte...

journal_title：Chinese medical journal

authors： Li X,Yin J,Cheng CM,Sun JL,Li Z,Wu YL

更新日期：2005-08-20 00:00:00

abstract：BACKGROUND:Colorectal cancer (CRC) is a heterogeneous disease; current research relies on cancer cell lines and animal cancer models, which may not precisely imitate inner human tumors and guide clinical medicine. The purpose of our study was to explore and further improve the process of producing three-dimensional (3D...

journal_title：Chinese medical journal

authors： Xie BY,Wu AW

更新日期：2016-10-20 00:00:00

abstract：OBJECTIVE:To investigate the prevalence and features of active human cytomegalovirus (HCMV) infection in children with systemic lupus erythematosus (SLE) and evaluate the diagnostic value of the HCMV using antigenemia assay, serum polymerase chain reaction (PCR) and serology test. METHODS:Twenty-one SLE children under...

journal_title：Chinese medical journal

authors： Zhang C,Shen K,Jiang Z,He X

更新日期：2001-12-01 00:00:00

abstract：OBJECTIVE:To analysis the pathological demography in Chinese patients undergoing renal biopsy from our nephrology center. METHODS:Between January 1979 and October 2000 in Jinling Hospital, Nanjing, China, 10,002 attempts of percutaneous renal were performed in patients with renal disease from 33 provinces of China. Th...

journal_title：Chinese medical journal

authors： Chen H,Tang Z,Zeng C,Hu W,Wang Q,Yu Y,Yao X,Wang J,Zhu M,Zhou H,Liu H,Liu Z,Li L

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:The myocardial ATP sensitive potassium channel (K(ATP) channel) has been known for more than two decades, the properties of this channel have been intensively investigated, especially the myocardial protection effect by opening this channel. Numerous studies, including hypothermic, using K(ATP) agonists to a...

journal_title：Chinese medical journal

authors： Jin SQ,Niu LJ,Deng CY,Yao ZB,Zhou YJ

更新日期：2006-10-20 00:00:00

abstract：BACKGROUND:Chronic graft-versus-host disease (GVHD), the commonest long-term complication after allogeneic hematopoietic stem cell transplantation (HSCT), has a negative impact on patients' health related quality of life (HRQoL). This study was designed to investigate the HRQoL in patients with chronic GVHD in China. ...

journal_title：Chinese medical journal

authors： Mo XD,Xu LP,Liu DH,Chen YH,Zhang XH,Chen H,Han W,Wang Y,Wang FR,Wang JZ,Liu KY,Huang XJ

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Colloid carcinomas of the pancreas have better prognosis than ordinary ductal adenocarcinoma, and preoperative distinction of colloid carcinoma from other pancreatic tumors is valuable for patient therapeutic planning and prognosis assessment. However, data about CT features of colloid carcinoma are very lim...

journal_title：Chinese medical journal

authors： Ren FY,Shao CW,Zuo CJ,Lu JP

更新日期：2010-05-20 00:00:00

abstract：BACKGROUND:Green tea has been shown to improve cholesterol metabolism in animal studies, but the molecular mechanisms underlying this function have not been fully understood. Long non-coding RNAs (lncRNAs) have recently emerged as a major class of regulatory molecules involved in a broad range of biological processes a...

journal_title：Chinese medical journal

authors： Liu G,Zheng X,Xu Y,Lu J,Chen J,Huang X

更新日期：2015-01-05 00:00:00

abstract：BACKGROUND:Bone morphogenetic protein (BMP) is a member of the superfamily of transforming growth factor-beta. Recent studies show that it is an indispensable factor in hematopoiesis. To better characterize the effect of recombinant human BMP (rhBMP)-2 in hematopoiesis, we set out to determine whether rhBMP-2 could pro...

journal_title：Chinese medical journal

authors： Liu SB,Hu PZ,Hou Y,Li P,Cao W,Tian Q

更新日期：2009-04-05 00:00:00

abstract：BACKGROUND:Alcohol has been used for treating simple renal cysts since 1981. Since then, various observational studies have examined the technique, but they differ significantly in the details of the procedures and efficacy measures used. This has made it difficult to assess the safety and efficacy of this technique. W...

journal_title：Chinese medical journal

authors： Li YZ,Li MX,Wang T,Yang LC,Feng P,Gou ZP,Yuan JY,Zhang W

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Left ventricular hypertrophy (LVH) and geometric abnormality are associated with morbidity and mortality of cardiovascular disease and stroke. Hypertension is the major cause of LVH. Yet the prevalence and other risk factors of LVH and geometric abnormality in Chinese hypertensive population are unknown. The...

journal_title：Chinese medical journal

authors： Wang SX,Xue H,Zou YB,Sun K,Fu CY,Wang H,Hui RT

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Idiopathic choroidal neovascularization (ICNV) is an uncommon disorder affecting primarily individuals younger than the age of 50 years. In CNV patients, no apparent cause can be determined. This study aimed to evaluate the functional and morphological change of the retina with ICNV in young adults. METHODS...

journal_title：Chinese medical journal

authors： Wang WQ,Liu HY,Lu FQ,Hu WT,Gong YY,Wu Y,Xu S,Wang WJ,Xu X,Wang FH,Sun XD

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVE:To investigate the protective effect of dl-3-n-butylphthalide (NBP) as an anti-cerebral ischemic drug on brain damage 24 h after closed head injury in mice. METHODS:Closed head injury was induced by dropping a 50-g weight from a height of 18 cm on a metal impounder resting on the parietal bone in mice. RESU...

journal_title：Chinese medical journal

authors： Chong Z,Feng Y

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:The endovascular treatment of abdominal aortic aneurysm (AAA) has improved greatly in the last 15 years. The present study aimed to evaluate the endografting experience for the treatment of unfavorable abdominal aortic aneurysm (uAAA). METHODS:During December 2001 and December 2007, 41 patients with uAAA we...

journal_title：Chinese medical journal

authors： Hu ZJ,Chang GQ,Li XX,Huang XL,Yin HH,Wang SM

更新日期：2009-04-05 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate the potential relationship between the dynamic expression of Toll-like receptor 2 and 4 (TLR2/4) in peripheral blood mononuclear cells as well as changes in serum concentration of inflammatory factors and acute lung injury (ALI) in patients after orthotopic liver tran...

journal_title：Chinese medical journal

authors： Chi XJ,Cai J,Luo CF,Cheng N,Hei ZQ,Li SR,Luo GJ

更新日期：2009-04-20 00:00:00

abstract：:The protective effect of improving the microcirculation on the retinal ganglion cells (RGC) and the ultrastructure of the optic nerve after intravenous (i.v.) use of Salviae miltiorrhiza (SMR) was studied in a chronic intraocular hypertension model in 36 rabbits. These rabbits were treated with topical 0.5% timolol, o...

journal_title：Chinese medical journal

authors： Zhu MD,Cai FY

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:Enhanced recovery after surgery (ERAS) protocols are a series of perioperative care to optimize preoperative preparation, prevent postoperative complications, minimize stress, and speed up recovery. This study aimed to assess the impact of ERAS protocols for functional endoscopic sinus surgery (FESS) in pati...

journal_title：Chinese medical journal

authors： Wu XF,Kong WF,Wang WH,Yuan LX,Xu HQ,Qi M,Zhou SL,Yang QT

更新日期：2019-02-05 00:00:00

abstract：BACKGROUND:Retinol binding protein 4 (RBP4), as an adipocyte secreted cytokine, was recently found to be inversely correlated with expression of glucose transporter 4 (GLUT4) in insulin resistance (IR) state and to have an intimate relationship with IR and type 2 diabetes mellitus (T2DM). The present study aimed to eva...

journal_title：Chinese medical journal

authors： Zhang W,Xu YC,Guo FJ,Meng Y,Li ML

更新日期：2008-11-05 00:00:00

abstract：BACKGROUND:Apoptosis is a major cause of ischemic heart dysfunction. Apelin, the endogenous ligand for the G-protein-coupled APJ receptor, has been reported to exert cardioprotective effects during myocardial injury. The aim of this study was to investigate the effects of apelin on apoptosis of rat cardiomyocytes induc...

journal_title：Chinese medical journal

authors： Zhang Z,Yu B,Tao GZ

更新日期：2009-10-05 00:00:00

abstract：BACKGROUND:Cholesterol-lowering therapy with statins has been reported to reduce the morbidity and mortality of cardiovascular diseases. This study aimed to investigate the effects of combined application of extended-release niacin and atorvastatin on lipid profile modification and the risks of adverse events in patien...

journal_title：Chinese medical journal

authors： Sang ZC,Wang F,Zhou Q,Li YH,Li YG,Wang HP,Chen SY

更新日期：2009-07-20 00:00:00

abstract：BACKGROUND:The reverse obliquity inter-trochanteric fracture is a distinct fracture pattern that is mechanically different from most inter-trochanteric fractures and the optional treatment of it is still controversial. The purpose of this study was to compare differences in the efficacy of a novel nail (medial support ...

journal_title：Chinese medical journal

authors： Nie SB,Zhao YP,Li JT,Zhao Z,Zhang Z,Zhang LC,Tang PF

更新日期：2020-11-20 00:00:00

abstract：BACKGROUND:Assessment of perfusion in the early period of acute renal failure (ARF) is important, and can not be made by conventional ultrasound. The aim of this study was to prospectively test in a rabbit ARF model whether real-time contrast-enhanced ultrasound (CEUS) can quantitatively evaluate the hemodynamic change...

journal_title：Chinese medical journal

authors： Dong Y,Wang WP,Cao JY,Fan PL,Lin XY

更新日期：2012-02-01 00:00:00

abstract：OBJECTIVE:To investigate the correlation between glutathione S-transferase (GST) M1 and T1 genotypes and endometriosis risk (EM). METHODS:Polymerase chain reaction (PCR) technique was used to detect the presence or absence of the GSTM1 and GSTT1 genes in genomic DNA isolated from the blood samples of 68 Han Chinese wo...

journal_title：Chinese medical journal

authors： Lin J,Zhang X,Qian Y,Ye Y,Shi Y,Xu K,Xu J

更新日期：2003-05-01 00:00:00

abstract：OBJECTIVE:To investigate molecular events of exocytosis in cultured human pheochromocytoma cells with stimulation. METHODS:The cultured pheochromocytoma cells prepared from human adrenal pheochromocytoma tumor were stimulated for the release of catecholamines by depolarization with the administration of 50 mmol/L KCl....

journal_title：Chinese medical journal

authors： Lee YS,Chou YY

更新日期：1998-04-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to summarize recent studies on nondopaminergic options for the treatment of motor symptoms in Parkinson's disease (PD). DATA SOURCES:Papers in English published in PubMed, Cochrane, and Ovid Nursing databases between January 1988 and November 2016 were searched using the following k...

journal_title：Chinese medical journal

authors： Du JJ,Chen SD

更新日期：2017-08-05 00:00:00

abstract：OBJECTIVE:To explore the management of cerebral ischemia caused by Takayasu's arteritis. METHODS:Ninety-three cases treated from June 1984 to September 1999 at the General Post & Telecom Hospital, the Sir Run Run Shaw Hospital, the First Affiliated Hospital of Zhejiang University, the Second Medical College of Beijing...

journal_title：Chinese medical journal

authors： Wang Z,Shen L,Yu J,Gu Y,Wang S,Guan H,Wu Q,Zhang X,Li M,Wu J,Li G,Pan S,Zhang H,Jin W

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:The baseline characteristics of patients in a multinational trial are possibly related to cardiovascular outcome. This study compared the baseline characteristics of patients recruited in China with those recruited in other countries. METHODS:A total of 508 Chinese hypertensive men and 728 women over the ag...

journal_title：Chinese medical journal

authors： Liu LS,Wang JG,Shu-Ping M,Wang W,Lu FH,Zhang LQ,Banya W,Peters R,Beckett N,Fletcher A,Bulpitt CJ

更新日期：2008-08-20 00:00:00

abstract：OBJECTIVE:To determine the role of systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction syndrome (MODS), and evaluate the progress from SIRS to MODS and the therapeutic strategies for acute necrotizing pancreatitis (ANP). METHODS:Rat ANP models were made by retrograde injection of 3.5% sodium ...

journal_title：Chinese medical journal

authors： Zhang Q,Ni Q,Cai D,Zhang Y,Zhang N,Hou L

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:Smoking and body mass index (BMI) are the key risk factors for chronic obstructive pulmonary disease (COPD). Adiponectin with both anti-inflammatory and pro-inflammatory properties is a vital modulator of inflammatory processes, which is expressed in epithelial cells in the airway in COPD-emphysema. The aim ...

journal_title：Chinese medical journal

authors： Wang RY,Liu H,Ma LJ,Xu JY

更新日期：2016-01-20 00:00:00

abstract：BACKGROUND:The growing enthusiasm for coronary artery bypass grafting (CABG) without cardiopulmonary bypass (CPB) is emerging, but the role of off-pump coronary artery bypass (OPCAB) in clinical practice remains controversial. The purpose of this study was to assess differences in the incidences of stroke, atrial fibri...

journal_title：Chinese medical journal

authors： Chen YB,Shu J,Yang WT,Shi L,Guo XF,Wang FG,Qian YY

更新日期：2012-01-01 00:00:00