Menopausal Symptoms and Sleep Quality During Menopausal Transition and Postmenopause.

abstract：OBJECTIVE:This review discusses the current status and progress in studies on the roles of hydrogen sulfide (H(2)S) in regulation of neurotoxicity, neuroprotection, and neuromodulator, as well as its therapeutic potential for neurodegenerative disorders. DATA SOURCES:The data used in this review were mainly from Medli...

journal_title：Chinese medical journal

authors： Zhou CF,Tang XQ

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Exposure of adult mice to more than 95% O(2) produces a lethal injury by 72 hours. Nitric oxide synthase (NOS) is thought to contribute to the pathophysiology of murine hyperoxia-induced acute lung injury (ALI). Osteopontin (OPN) is a phosphorylated glycoprotein produced principally by macrophages. OPN inhib...

journal_title：Chinese medical journal

authors： Zhang XF,Liu S,Zhou YJ,Zhu GF,Foda HD

更新日期：2010-04-05 00:00:00

abstract：OBJECTIVE:To evaluate the effects of nitric oxide inhibitor on prostacyclin (PGI2) biosynthesis and the role of PGI2 in hyperhemodynamics of portal hypertension. METHODS:Sprague Dawley rats were divided into four groups: intrahepatic portal hypertension (IHPH) by injection of CCl4, prehepatic portal hypertension (PHPH...

journal_title：Chinese medical journal

authors： Cao H,Wu Z,Zhou J,Chen Z,Kuang Y

更新日期：1999-06-01 00:00:00

abstract：OBJECTIVE:Renal fibrosis is the most common manifestation of chronic kidney disease (CKD). Noting that existing treatments of renal fibrosis only slow disease progression but do not cure it, there is an urgent need to identify novel therapies. Hydrogen sulfide (H2S) is a newly discovered endogenous small gas signaling ...

journal_title：Chinese medical journal

authors： Wang Y,Xing QQ,Tu JK,Tang WB,Yuan XN,Xie YY,Wang W,Peng ZZ,Huang L,Xu H,Qin J,Xiao XC,Tao LJ,Yuan QJ

更新日期：2019-12-05 00:00:00

abstract：BACKGROUND:Hypoxia-inducible factor-1alpha (HIF-1alpha) is a transcriptional factor that could improve the stimulation of angiogenesis and the metabolic adaptation of tumor cells to hypoxia. A recent study showed that HIF-1alpha could induce colon cancer cells epithelial-mesenchymal transition (EMT). However, no eviden...

journal_title：Chinese medical journal

authors： Luo Y,He DL,Ning L,Shen SL,Li L,Li X

更新日期：2006-05-05 00:00:00

abstract：OBJECTIVE:To induce islet grafting tolerance by intravenous injection of anti-CD4, anti-CD8 immunotoxins and donor soluble antigen. METHODS:Fourteen days or 7 days prior to transplantation, the immunotoxin of anti-CD4, anti-CD8 200 micrograms respectively, and donor soluble antigen 500 micrograms were intravenously in...

journal_title：Chinese medical journal

authors： Lan P,Yan L,Xiao L

更新日期：1999-12-01 00:00:00

abstract：OBJECTIVE:To test the immunosuppressive effect of cyclosporine (Cs) in a polymer placed in the anterior chamber of corneal allograft recipients. METHODS:Wistar inbred rats with vascularized corneas were recipients of corneal allografts from Sprague-Dawley donor rats. Rats underwent penetrating keratoplasty and were di...

journal_title：Chinese medical journal

authors： Xie L,Shi W,Wang Z,Bei J,Wang S

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Effects of icariin on airway inflammation in asthmatic rats and the intervention of LPS induced inflammation are interfered with the machanism of icariin. Our study aimed to observe the effect of icariin on ovalbumin-induced imbalance of Th1/Th2 cytokine expression and its mechanism. METHODS:Sixty male SD r...

journal_title：Chinese medical journal

authors： Xu CQ,LE JJ,Duan XH,DU WJ,Liu BJ,Wu JF,Cao YX,Dong JC

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Peutz-Jeghers syndrome (PJS) is an autosomal dominantly inherited disease. STK11/LKB1 gene germline mutations have been identified as responsible for PJS. In our study, we investigated the molecular basis of PJS and evaluated correlation between the STK11 mutations and the Chinese population. METHODS:We col...

journal_title：Chinese medical journal

authors： Zuo YG,Xu KJ,Su B,Ho MG,Liu YH

更新日期：2007-07-05 00:00:00

abstract：:The effect of exercise on pulmonary gas exchange, arterial oxygenation, oxygen transport and delivery, and hemodynamics are studied in 100 patients with chronic obstructive pulmonary diseases. According to the change of PaO2 or PaCO2 induced by exercise, patients were divided into two groups. Group A (n = 52) had sign...

journal_title：Chinese medical journal

authors： Zeng GB,Zhang ZX,Xu YJ,Duan SF

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Preeclampsia, characterized by hypertension and proteinuria, is a multifactorial disease associated with shallow invasion of trophoblast cells and inadequate spiral artery remodeling. Trophoblast and tumor cells have similar invasion mechanism. Prostasin is closely related to tumor development, invasion and ...

journal_title：Chinese medical journal

authors： Luo D,Zhang Y,Bai Y,Liu X,Gong Y,Zhou B,Zhang L,Luo L,Zhou R

更新日期：2014-01-01 00:00:00

abstract：:A 10-year-old boy who had previously undergone surgical correction for tetralogy of Fallot was referred for cardiac catheterization because of recurrent symptomatic postoperative heart failure owing to major aortopulmonary collateral arteries (MAPCAs). A successful occlusion of these MAPCAs was achieved percutaneously...

journal_title：Chinese medical journal

authors： Tang L,Zhou SH

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:The mitochondrial displacement loop (D-loop) accumulates mutations and single nucleotide polymorphisms (SNPs) at a higher frequency than other regions of mitochondrial DNA (mtDNA). We previously identified disease risk-associated SNPs in the D-loop of chronic kidney disease (CKD) patients; in this study, we ...

journal_title：Chinese medical journal

authors： Bai Y,Guo Z,Xu J,Zhang J,Cui L,Zhang H,Zhang S,Ai X

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Renal artery stenosis (RAS) is always associated with abnormalities in renal microvascular perfusion (RMP). However, few imaging methods can simultaneously evaluate the degree of luminal stenosis and RMP. Thus, this study will aim to evaluate the feasibility of using contrast-enhanced ultrasound (CEUS) for a...

journal_title：Chinese medical journal

authors： Ren JH,Ma N,Wang SY,Sun YJ,Zhang YW,Guo FJ,Li YJ,Li TH,Ai H,Zhang WD,Li P,Ma WH

更新日期：2019-01-05 00:00:00

abstract：BACKGROUND:Monilethrix is an autosomal dominant hair disorder characterized clinically by alopecia and follicular papules. In this study, we collected a Han monilethrix family to detect the mutations in patients and investigated the correlation between the genotype and phenotype of monilethrix. METHODS:In this study, ...

journal_title：Chinese medical journal

authors： Ye ZZ,Nan X,Zhao HS,Chen XR,Song QH

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVE:To investigate the correlation between glutathione S-transferase (GST) M1 and T1 genotypes and endometriosis risk (EM). METHODS:Polymerase chain reaction (PCR) technique was used to detect the presence or absence of the GSTM1 and GSTT1 genes in genomic DNA isolated from the blood samples of 68 Han Chinese wo...

journal_title：Chinese medical journal

authors： Lin J,Zhang X,Qian Y,Ye Y,Shi Y,Xu K,Xu J

更新日期：2003-05-01 00:00:00

abstract：Background:Facioscapulohumeral muscular dystrophy (FSHD) is characterized by asymmetric muscular deficit of facial, shoulder-girdle muscles, and descending to lower limb muscles, but it exists in several extramuscular manifestations or overlapping syndromes. Herein, we report a "complex disease plus" patient with FSHD1...

journal_title：Chinese medical journal

authors： Lin XD,He JJ,Lin F,Chen HZ,Xu LQ,Hu W,Cai NQ,Lin MT,Wang N,Wang ZQ,Xu GR

更新日期：2018-09-20 00:00:00

abstract：BACKGROUND:The usefulness of in-phase/opposed-phase imaging and diffusion weighted imaging (DWI) in differentiating benign and neoplastic vertebral fractures has been described. In this study, we aimed to evaluate the influence of the severity of vertebral damage on the diagnostic performance of these two technologies....

journal_title：Chinese medical journal

authors： Lin F,Lei Y,Li YB

更新日期：2009-06-05 00:00:00

abstract：BACKGROUND:The expression of TES, a novel tumor suppressor gene, is found to be down-regulated in the left anterior descending aorta of patients with coronary artery disease (CAD) compared with non-CAD subjects. This study aimed to investigate the expression of TES during the development of atherosclerosis in rabbits. ...

journal_title：Chinese medical journal

authors： Zhang Y,Yuan M,Li HM,Lao M,Xu Z,Li GP

更新日期：2015-06-20 00:00:00

abstract：OBJECTIVE:The objective was to provide a brief history of J wave syndromes and to summarize our current understanding of their molecular, ionic, cellular mechanisms, and clinical features. We will also discuss the existing debates and further direction in basic and clinical research for J wave syndromes. DATA SOURCES:...

journal_title：Chinese medical journal

authors： Li GL,Yang L,Cui CC,Sun CF,Yan GX

更新日期：2015-04-05 00:00:00

abstract：OBJECTIVE:To investigate the significance of telomerase activity in urine in the diagnosis and recurrence surveillance of urothelial carcinoma. METHODS:Telomerase activity in urine of 54 cases of urothelial carcinoma (urothelial carcinoma group) was estimated by polymerase chain reaction-enzyme-linked immunosorbent as...

journal_title：Chinese medical journal

authors： Li Z,Kong C,Wang P,Liu X,Liu T

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:In county-level tuberculosis (TB) dispensaries in China, the accurate diagnosis of sputum smear-negative pulmonary tuberculosis (SNPT) needs to be improved by developing and validating clinical and radiographic predictors. METHODS:The study was conducted simultaneously in three counties per province in Chon...

journal_title：Chinese medical journal

authors： Li XX,Jiang SW,Zhang H,Jing KH,Wang L,Li WB,Liu XQ,Yao HY,Wang LX

更新日期：2013-01-01 00:00:00

abstract：:Twenty-seven samples of pleomorphic salivary adenoma (PSA) were examined for expression and structure of c-myc, c-Ha-ras, c-erbB-2, c-sis oncogenes by RNA dot blot, DNA dot blot and Southern blot hybridization. Eighteen of 25 PSA showed 5.02 +/- 4.74 fold overexpression of c-myc oncogene, 6 of 19 PSA had 4.91 +/- 3.87...

journal_title：Chinese medical journal

authors： Xue H,Situ ZQ,Wang CJ,Wu JZ

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Orthotopic liver transplantation (OLT) has become the therapeutic option of choice for end-stage liver disease. The aim of this study was to investigate the changes of splenic morphology, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), apparent diffusion coefficient (ADC) values and explore their...

journal_title：Chinese medical journal

authors： Wang J,Liang Y,Yan R,Jiang Z,Liu J,Hu B,He B,Ren L,Chen J,Shan H

更新日期：2014-01-01 00:00:00

abstract：:1 141 serum samples from various population groups in north China were examined for C100-3Ab by ELISA. Antibody to C100-3 antigen derived from HCV genome (C100-3A) and HBsAg were measured in 438 normal population in Beijing. The C100-3Ab positive rate was 2.1% and the HBsAg positive rate was 2.5%. There is increased o...

journal_title：Chinese medical journal

authors： Tao QM,Wang Y,Wang H,Chen WR,Sun Y,Meng Q,Watanabe J,Nishioka K

更新日期：1992-03-01 00:00:00

abstract：:Plasma levels of tissue plasminogen activator (tPA) antigen, tPA activity and plasminogen activator inhibitor (PAI) activity were determined in 40 cases of acute myocardial infarction (AMI) at the onset and 2-4 weeks after the onset of the disease. 24 healthy subjects served as controls. At the onset of AMI, mean plas...

journal_title：Chinese medical journal

authors： Chen HZ,Jia HY,Song HY,Wang JY

更新日期：1990-07-01 00:00:00

abstract：:Psoralen (PSO) was found cytotoxic against in vitro cultured human mucoepidermoid carcinoma cells of MEC-1 cell line. Its IC50 value was 8.6 micrograms/ml, and relative antitumor activity (RAA) 15. PSO suppressed DNA synthesis, damaged microvilli and cell membrane, and induced degeneration of mitochondria. It inhibite...

journal_title：Chinese medical journal

authors： Wu JZ,Situ ZQ,Wang W,Chen JY,Liu B

更新日期：1992-11-01 00:00:00

abstract：:One 22-month-old boy who was admitted for a fever lasting 6 days as well as a cough and wheezing lasting 2 days was reported. He was diagnosed with influenza A (H1N1, severe type), severe pneumonia, acute respiratory distress syndrome (ARDS), Evans syndrome and multiple organ failure. This is the first case of novel i...

journal_title：Chinese medical journal

authors： Chen H,Jia XL,Gao HM,Qian SY

更新日期：2011-06-01 00:00:00

abstract：:The effect of harringtonine (HA) in various concentrations on HL-60 was evaluated. 0.10 microgram/ml HA showed a strong cell killing effect, and 0.025 microgram/ml HA a weak differentiation induction accompanied by cell growth retardation. Differentiation induction did not occur in 5 other human leukemic cell lines. W...

journal_title：Chinese medical journal

authors： Chen SS,Wang P,Fu JY,Chen LL,Zhao FS,Shan FX

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND:The emergence of bacterial resistance to commonly used antibiotics, such as macrolides, is complicating the management of respiratory tract infections (RTIs). Telithromycin, a ketolide antimicrobial structurally related to macrolides, is approved for the treatment of community-acquired RTIs, and shows lower ...

journal_title：Chinese medical journal

authors： Li XM,Wang FC,Yang F,Jin YH

更新日期：2013-01-01 00:00:00