Genomics of hepatitis B virus-related hepatocellular carcinoma and adjacent noncancerous tissues with cDNA microarray.

abstract：BACKGROUND:Receptor activator of nuclear factor kappa B (NF-κB) ligand (RANKL) and osteoprotegerin (OPG) have been recently shown to play important roles in bone resorption. The aim of this study was to investigate the possible association between the expression of bone resorption regulators (RANKL and OPG) and inflamm...

journal_title：Chinese medical journal

authors： Fan R,Sun B,Zhang CF,Lü YL,Xuan W,Wang QQ,Yin XZ

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Surgical resection is generally considered the main curative treatment for intrahepatic biliary cystadenocarcinoma (IBCA) or suspected IBCAs, but controversy exists regarding the prognosis for IBCAs. This study aimed to describe the clinicopathological characteristics of IBCA and identify prognostic factors ...

journal_title：Chinese medical journal

authors： Xu MY,Shi XJ,Wan T,Liang YR,Wang HG,Zhang WZ,He L,Chen MY,Lyu SC,Zhang WW,Li HX

更新日期：2015-05-05 00:00:00

abstract：BACKGROUND:P53 is one of the most studied tumor suppressors in the cancer research, and over 50% of human tumors carry P53 mutations. MDM-2 is amplified and/or overexpressed in a variety of human tumors of diverse tissue origin. The aim of this study was to examine the expression of P53 protein and MDM-2 protein in gli...

journal_title：Chinese medical journal

authors： Wang AL,Liu ZX,Li G,Zhang LW

更新日期：2011-08-01 00:00:00

abstract：:The vascular pedicled periosteum was used in 11 cases in our hospital for the treatment of femoral neck fracture with good result. The follow-up period ranged from 2 to 6 years, with an average of 4 years. Animal experiment was made to elucidate the repairing process. It demonstrated that the pedicled periosteum playe...

journal_title：Chinese medical journal

authors： Zhu SX,Shen YN,Lu SB,Zhang BX,Wang JF

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) core antigen assays have been produced to exclude infectious donations collected during the preseroconversion window phase (PWP). For the same purpose, we evaluated the specificity and sensitivity of a novel hepatitis C virus NS3 antigen detection immunoassay and the application of th...

journal_title：Chinese medical journal

authors： Xie L,Wu XD,Huang DZ,Chen HL,He LX,Wang J,Han DK

更新日期：2007-02-20 00:00:00

abstract：BACKGROUND:The role of plasma high sensitivity C-reactive protein (hs-CRP) in in-stent restenosis (ISR) remains controversial. We investigated plasma hs-CRP level at both admission and follow-up in patients with stable angina (SA) after successful coronary stenting in order to clarify the predictive value of hs-CRP for...

journal_title：Chinese medical journal

authors： Xu YL,Li JJ,Xu B,Zhu CG,Yang YJ,Chen JL,Qiao SB,Yuan JQ,Qin XW,Ma WH,Yao M,Liu HB,Wu YJ,Chen J,You SJ,Dai J,Xia R,Gao RL

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVE:To study the effect of pericardial devascularization combined with Latarjet's innervation on portal hypertension. METHODS:Forty-eight patients undergoing pericardial devascularization combined with Latarjet's innervation were compared with 57 patients with devascularization. Clinical results were evaluated b...

journal_title：Chinese medical journal

authors： Li S,Wu E,Huang J,Luo C

更新日期：1998-12-01 00:00:00

abstract：Background:Patients with major depressive disorder (MDD) usually have high risk of suicidality. Few studies have investigated the effects of stressful life events (SLEs) on the risk of suicide in Chinese patients who have developed MDD. This study aimed to investigate the impact of SLEs on suicidal risk in Chinese pati...

journal_title：Chinese medical journal

authors： Lin JY,Huang Y,Su YA,Yu X,Lyu XZ,Liu Q,Si TM

更新日期：2018-04-20 00:00:00

abstract：OBJECTIVE:To characterize effects of the GP Ib alpha mutation (A156V) on its interaction with von Willebrand factor (vWf) under high fluid shear stress. METHODS:The residue A156 of GP Ib alpha was converted to a valine and the mutant expressed in CHO cells expressing wild-type GP Ib beta and GPIX. The transfected cell...

journal_title：Chinese medical journal

authors： Dong J,Li C,Schade AJ,Fredrickson BJ,Sun L,McIntire LV,López JA

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND:Borderline gastrointestinal stromal tumors (GISTs) are intermediate tumors between benign and malignant variants; however, the clinical and pathological features of borderline GISTs remain poorly defined. This study aimed to characterize GISTs and to identify a set of borderline criteria for practical use. ...

journal_title：Chinese medical journal

authors： Shi Y,Hou YY,Lu SH,Zhou Y,Xu JF,Ji Y,Hou J,Xu C,Liu YL,Tan YS,Zhu XZ

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Occult stress urinary incontinence may lead to de novo stress urinary incontinence after pelvic floor repair surgery. A measurement of pudendal nerve terminal motor latency can reflect the integrity of the nerves. We aimed to explore the value of pudendal nerve terminal motor latency in the diagnosis of occu...

journal_title：Chinese medical journal

authors： Zhu L,Hai N,Lang JH,Yu SY,Li B,Wong F

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Major atrial coronary arteries, including the sinus node artery (SNA), were commonly found in the areas involved in atrial fibrillation (AF) ablation and could cause difficulties in achieving linear block at the left atrial (LA) roof. The SNA is a major atrial coronary artery of the atrial coronary circulati...

journal_title：Chinese medical journal

authors： Zhang ZJ,Chen K,Tang RB,Sang CH,Lao EP,Yan Q,He XN,DU X,Long DY,Yu RH,Dong JZ,Ma CS

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Hepatocyte growth factor (HGF) treats ischemic disease by promoting arteriogenesis, however, its mechanism of action is not known. The notch signaling pathway plays an important role in neovascularization. The relationship between the proliferation and migration ability of artery endothelial cells and the Dl...

journal_title：Chinese medical journal

authors： Gao YF,Ha XQ,Lü TD,Han JP

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:To investigate the correlation between glutathione S-transferase (GST) M1 and T1 genotypes and endometriosis risk (EM). METHODS:Polymerase chain reaction (PCR) technique was used to detect the presence or absence of the GSTM1 and GSTT1 genes in genomic DNA isolated from the blood samples of 68 Han Chinese wo...

journal_title：Chinese medical journal

authors： Lin J,Zhang X,Qian Y,Ye Y,Shi Y,Xu K,Xu J

更新日期：2003-05-01 00:00:00

abstract：OBJECTIVE:To assess the feasibility of detecting SYT-SSX fusion transcripts in paraffin-embedded tissues of synovial sarcoma by reverse transcription-polymerase chain reaction (RT-PCR). METHODS:RT-PCR was used to amplify the SYT-SSX fusion transcripts using archival formalin-fixed paraffin-embedded tumor specimens fro...

journal_title：Chinese medical journal

authors： Wei Y,Wang J,Zhu X,Shi D,Hisaoka M,Hashimoto H

更新日期：2002-07-01 00:00:00

abstract：:Metastases to the breast from extramammary neoplasms are very rare, constituting 2.7% of all malignant breast tumours. The most common primary tumor metastatic to the breast is primary breast cancer. Rectal cancer metastasizing to the breast is extremely rare. We report a case of aggressive rectal carcinoma with metas...

journal_title：Chinese medical journal

authors： Li J,Fang Y,Li A,Li F

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Although acute congestive heart failure (CHF) patients typically present with abnormal auscultatory findings on lung examination, lung sounds are not normally subjected to rigorous analysis. The goals of this study were to use a computerized analytic acoustic tool to evaluate lung sound patterns in CHF patie...

journal_title：Chinese medical journal

authors： Wang Z,Xiong YX

更新日期：2010-05-05 00:00:00

abstract：:Lectin binding patterns in psoriasis, lichen planus and seborrheic keratosis lesions were studied using 14 different biotinyl lectins and avidin-horseradish peroxidase. Compared with normal epidermis, there were significant quantitative and qualitative differences, some of which were characteristic. ...

journal_title：Chinese medical journal

authors： Gao MY,Lin XR,Miao Q

更新日期：1992-12-01 00:00:00

abstract：BACKGROUND:The incidence of vancomycin-resistant enterococci (VRE) appeared to be increasing in China, but very few nosocomial outbreaks have been reported. Our hospital had experienced an outbreak of VRE since March 2008 to March 2009. The objective of this study was to analyze the molecular features of the isolates a...

journal_title：Chinese medical journal

authors： Xu HT,Tian R,Chen DK,Xiao F,Nie ZY,Hu YJ,Zhang XZ,Li JM

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Bone grafting is commonly used to repair bone defects. As the porosity of the graft scaffold increases, bone formation increases, but the strength decreases. Early attempts to engineer materials were not able to resolve this problem. In recent years, nanomaterials have demonstrated the unique ability to impr...

journal_title：Chinese medical journal

authors： Tang D,Xu G,Yang Z,Holz J,Ye X,Cai S,Yuan W,Wang Y

更新日期：2014-01-01 00:00:00

abstract：:The phenotypes of mononuclear cells in 16 patients with mycosis fungoides (MF) (8 were in tumor stage and 8 in pretumor stage) were tested by ABC immunochemical technique. The results showed that the percentage of CD38 and Leu6(+) cells in tumor stage was higher than that in pretumor stage. CD38 was identified to be a...

journal_title：Chinese medical journal

authors： Liu JH,Zhang Q,Shi YF,Zeng XS,Wang XH,Li J,Chen Z,Shen DC

更新日期：1993-05-01 00:00:00

abstract：:The radiographic measurement of the prevertebral soft tissue of cervical vertebrae was performed in 87 normal adults. According to the results of the measurement, 10 mm and 20 mm were used as the upper limit normal values of the retropharyngeal and retrotracheal space respectively. We conclude that although the widene...

journal_title：Chinese medical journal

authors： Dai LY,Jia LS

更新日期：1994-06-01 00:00:00

abstract：BACKGROUND:The continual and rapid development of techniques which are used for diagnosis and treatment makes management of colorectal cancer more difficult depending on single discipline. Colorectal cancer multidisciplinary team (MDT) working model is recommended by UK and other countries, but there is little informat...

journal_title：Chinese medical journal

authors： Ye YJ,Shen ZL,Sun XT,Wang ZF,Shen DH,Liu HJ,Zhang WL,Chen YL,Zhou J,Poston GJ,Wang S

更新日期：2012-01-01 00:00:00

abstract：Background::Localized macular edema and retinal nerve fiber layer (RNFL) thinning have been reported shortly after laser in situ keratomileusis (LASIK) in adults. However, it is still unclear how LASIK affects the retina of children. This study aimed to investigate the macular retina and RNFL thickness in children with...

journal_title：Chinese medical journal

authors： Zhao PF,Zhou YH,Zhang J,Wei WB

更新日期：2017-09-20 00:00:00

abstract：BACKGROUND:Periostin originally designated osteoblast-specific factor 2 (OSF-2) is frequently found to be highly expressed in various types of human cancer cell lines in vitro and human cancer tissues in vivo. We proposed that periostin was a key factor during the process of proliferation and invasion in cancer cells. ...

journal_title：Chinese medical journal

authors： Liu C,Huang SJ,Qin ZL

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Ophthalmic gel has been developed to increase the drug concentration in aqueous humor and to retard the loss of drug from the conjunctival sac. The research was to compare the drug concentration in aqueous humor of cataract patients administered 0.3% gatifloxacin ophthalmic gel with that in patients administ...

journal_title：Chinese medical journal

authors： Liu X,Wang NL,Wang YL,Ma C,Ma L,Gao LX,Huang YX,Xiong SH,Wang K

更新日期：2010-08-05 00:00:00

abstract：:From April 1989 to July 1991, 72 patients with residual or recurrent nasopharyngeal carcinoma (NPC) were treated by MSH Ir-192 brachytherapy or combined external radiation therapy. All were proven histologically. 39 patients with residual disease and 6 with recurrent lesion at the primary site were identified after on...

journal_title：Chinese medical journal

authors： Gao L,Xu GZ,Yin WB,Yan JH,Cai WM,Gu XZ

更新日期：1993-06-01 00:00:00

abstract：OBJECTIVE:To investigate the use of the Gibbs-Sampler method in evaluating the relationship between clinic events and health risks in a meta-analysis of multiple clinical trials. METHODS:By using a generalized linear model with random-effects, Gibbs-Sampler technique was used in a meta-analysis of multiple clinical tr...

journal_title：Chinese medical journal

authors： Wang Y,Wang Y,Li L,Wang Z,Macus F,Salim Y

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:Magnetic resonance imaging (MRI) is commonly utilized as part of the diagnostic workup for the clinical diagnosis of glioblastoma multiforme (GBM), further guiding the clinical treatment of this aggressive cancer. Recent research has shown that microRNAs (miRNAs) may act as oncogenes, or in some cases, tumor...

journal_title：Chinese medical journal

authors： Li WB,Chen HY,Zhang W,Yan W,Shi R,Li SW,Jiang T

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:To explore the characteristics of Helicobacter pylori (H. pylori) antigen in serum and to evaluate its clinical diagnostic value. METHODS:Enzyme-linked immunosorbant assay (ELISA) was developed to detect the soluble H. pylori antigen (S-Hp) and circulatory specific H. pylori antigen immunocomplexes (Hp-IC) i...

journal_title：Chinese medical journal

authors： Zhu Y,Lin J,Li D,Du Q,Qian K,Wu Q,Zheng S

更新日期：2002-03-01 00:00:00