The role of sexual related Y gene detection in the diagnosis of patients with gonadal dysgenesis.

abstract：OBJECTIVES:To study the status of cochlear mitochondrial DNA (mtDNA) and to determine the location of mtDNA deletion in aged mice. METHODS:We detected cochlear mtDNA in 2, 7 - 10 and 17 - 19 month old mice by nested polymerase chain reaction (PCR) and DNA sequencing. RESULTS:mtDNA3867bp deletions were found in the co...

journal_title：Chinese medical journal

authors： Zhang X,Han D,Ding D,Dai P,Yang W,Jiang S,Salvi RJ

更新日期：2002-09-01 00:00:00

abstract：OBJECTIVE:To study the relationship between cartilage end-plate calcification and intervertebral disc degeneration. METHODS:An experimental model of cervical disc degeneration in rabbits was established by resection of the cervical supraspinous and interspinous ligaments and detachment of the posterior paravertebral m...

journal_title：Chinese medical journal

authors： Peng B,Hou S,Shi Q,Jia L

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND:Aquaporin-1 (AQP1) has involved in fluid transport in diverse pulmonary edema diseases. Our study aimed to explore the dynamic changes of AQP1 in pulmonary water metabolism in rats following traumatic brain injury (TBI) and the protective effect provided by shenmai injection. METHODS:Sixty male Sprague Dawl...

journal_title：Chinese medical journal

authors： Bai Y,Yao HX,Hu ML,Wang LR,Jin LD,Wang WT,Lin LN

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Collagen VI-related myopathies are autosomal dominant and recessive hereditary myopathies, mainly including Ullrich congenital muscular dystrophy (UCMD) and Bethlem myopathy (BM). Muscle magnetic resonance imaging (MRI) has been widely used to diagnosis muscular disorders. The purpose of this study was to ev...

journal_title：Chinese medical journal

authors： Fu J,Zheng YM,Jin SQ,Yi JF,Liu XJ,Lyn H,Wang ZX,Zhang W,Xiao JX,Yuan Y

更新日期：2016-08-05 00:00:00

abstract：BACKGROUND:Although a variety of risk factors of pneumonia after clipping or coiling of the aneurysm (post-operative pneumonia [POP]) in patients with aneurysmal subarachnoid hemorrhage (aSAH) have been studied, the predictive model of POP after aSAH has still not been well established. Thus, the aim of this study was ...

journal_title：Chinese medical journal

authors： Chen Y,Lian BQ,Peng L,Ding CY,Lin YX,Yu LH,Wang DL,Kang DZ

更新日期：2020-12-24 00:00:00

abstract：BACKGROUND:Morphologic imaging after radiofrequency ablation (RFA) of liver metastases is hampered by an inflammatory response in the ablation margin, making the identification of local tumor progression (LTP) difficult. The aim of this study was to evaluate the efficacy of early (18)F-FDG PET/CT scanning to monitor th...

journal_title：Chinese medical journal

authors： Liu ZY,Chang ZH,Lu ZM,Guo QY

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:The rapid transmission and high mortality rate made severe acute respiratory syndrome (SARS) a global threat for which no efficacious therapy is available now. Without sufficient knowledge about the SARS coronavirus (SARS-CoV), it is impossible to define the candidate for the anti-SARS targets. The putative ...

journal_title：Chinese medical journal

authors： Lu JH,Zhang DM,Wang GL,Guo ZM,Zhang CH,Tan BY,Ouyang LP,Lin L,Liu YM,Chen WQ,Ling WH,Yu XB,Zhong NS

更新日期：2005-05-05 00:00:00

abstract：OBJECTIVE:To understand whether very low density lipoprotein (VLDL) and oxidatively modified very low density lipoprotein (OX-VLDL) can stimulate vascular smooth muscle cells (SMCs) to express high level of monocyte chemotactic protein (MCP-1) mRNA. METHODS:LDL and VLDL were isolated from normal blood donors by densit...

journal_title：Chinese medical journal

authors： Ruan Q,Deng Z,Song J

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:Genetic factors contribute to the development of coronary artery disease (CAD). Recently, a missense mutation in the low density lipoprotein receptor related protein 6 (LRP6) gene, encoding low density lipoprotein receptor related protein 6, has been implicated in an autosomal dominant form of early-onset CA...

journal_title：Chinese medical journal

authors： Wang H,Liu QJ,Chen MZ,Li L,Zhang K,Cheng GH,Ma L,Gong YQ

更新日期：2012-02-01 00:00:00

abstract：:Two thousand patients aged 15 years and below, who underwent surgical treatment for intracranial tumors in Beijing Tiantan Hospital from 1955 to 1989, were studied. All of the tumors in this series have been verified by operative findings and histological studies. This series accounts for 15.1% of all cases of intracr...

journal_title：Chinese medical journal

authors： Luo SQ,Li DZ,Dong JF

更新日期：1992-06-01 00:00:00

abstract：OBJECTIVE:To investigate CTLA4-Ig's potential role in therapy for allergic asthma by blocking B7/CD28 interactions with cytotoxic T lymphocyte antigen 4-Ig (CTLA4-Ig). METHODS:We divided BALB/C mice into the three groups: Sham/Sham (control), ovalbumin (OVA)/OVA and mCTLA4-Ig. Blood, bronchoalveolar lavage, histology ...

journal_title：Chinese medical journal

authors： Wan H,Zhou M,Xu Q,Huang S,Deng W

更新日期：2003-03-01 00:00:00

abstract：:Psoralen (PSO) was found cytotoxic against in vitro cultured human mucoepidermoid carcinoma cells of MEC-1 cell line. Its IC50 value was 8.6 micrograms/ml, and relative antitumor activity (RAA) 15. PSO suppressed DNA synthesis, damaged microvilli and cell membrane, and induced degeneration of mitochondria. It inhibite...

journal_title：Chinese medical journal

authors： Wu JZ,Situ ZQ,Wang W,Chen JY,Liu B

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:Vascular endothelial growth factor (VEGF) is well known as a hypoxia-induced protein. That it markedly increased expression of VEGF and improvement of rat motor function after spinal cord injury suggested that VEGF could play a neuroprotective role in ischaemic tolerance. This study investigated whether vasc...

journal_title：Chinese medical journal

authors： Ding XM,Mao BY,Jiang S,Li SF,Deng YL

更新日期：2005-10-05 00:00:00

abstract：:The effect of exercise on pulmonary gas exchange, arterial oxygenation, oxygen transport and delivery, and hemodynamics are studied in 100 patients with chronic obstructive pulmonary diseases. According to the change of PaO2 or PaCO2 induced by exercise, patients were divided into two groups. Group A (n = 52) had sign...

journal_title：Chinese medical journal

authors： Zeng GB,Zhang ZX,Xu YJ,Duan SF

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:The Xpert MTB/RIF showed high sensitivity and specificity in previous studies carried out in different epidemiological and geographical settings and patient populations in high-burden tuberculosis (TB) countries. However, there were little data obtained by validation or demonstration study of the assay in Ch...

journal_title：Chinese medical journal

authors： Hu P,Bai L,Liu F,Ou X,Zhang Z,Yi S,Chen Z,Gong D,Liu B,Guo J,Tan Y

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To discuss the etiology, diagnostic criteria and treatment of Nelson's syndrome. METHODS:Twenty-three patients with Nelson's syndrome who were treated in our department over the last 19 years were analyzed retrospectively. Removal of adenoma by the transsphenoidal approach was done in 21 patients and by tran...

journal_title：Chinese medical journal

authors： Xing B,Ren Z,Su C,Wang R,Yang Y,Hu Y

更新日期：2002-08-01 00:00:00

abstract：:1 141 serum samples from various population groups in north China were examined for C100-3Ab by ELISA. Antibody to C100-3 antigen derived from HCV genome (C100-3A) and HBsAg were measured in 438 normal population in Beijing. The C100-3Ab positive rate was 2.1% and the HBsAg positive rate was 2.5%. There is increased o...

journal_title：Chinese medical journal

authors： Tao QM,Wang Y,Wang H,Chen WR,Sun Y,Meng Q,Watanabe J,Nishioka K

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND:Ahmed Glaucoma Valve implantation (AGVI) is used to treat refractory glaucoma. Breakdown of the blood-aqueous barrier (BAB) has been noted after some surgical techniques. The current study was designed to assess BAB disruption after AGVI. METHODS:Anterior chamber protein content was measured by the laser fl...

journal_title：Chinese medical journal

authors： Zhou MW,Wang W,Chen SD,Huang WB,Zhang XL

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:The baseline characteristics of patients in a multinational trial are possibly related to cardiovascular outcome. This study compared the baseline characteristics of patients recruited in China with those recruited in other countries. METHODS:A total of 508 Chinese hypertensive men and 728 women over the ag...

journal_title：Chinese medical journal

authors： Liu LS,Wang JG,Shu-Ping M,Wang W,Lu FH,Zhang LQ,Banya W,Peters R,Beckett N,Fletcher A,Bulpitt CJ

更新日期：2008-08-20 00:00:00

abstract：Background:The outcome of pediatric deceased donor liver transplantation (LT) has not been well studied, especially pediatric deceased donor livers used in adult transplantation. This study aimed to evaluate the efficacy of LT using pediatric deceased donor livers and compare the outcomes between pediatric-to-pediatric...

journal_title：Chinese medical journal

authors： Zhang R,Zhu ZJ,Sun LY,Wei L,Qu W

更新日期：2018-03-20 00:00:00

abstract：BACKGROUND:Recently, conservative surgery is acceptable in young patients with borderline ovarian tumor and ovarian cancer. The preservation of these patients' future fertility has been the focus of recent interest. This study aimed to observe the effect of gonadotropin-releasing hormone agonists (GnRHa) cotreatment du...

journal_title：Chinese medical journal

authors： Zhu HL,Wang Y,Li XP,Wang CH,Wang Y,Cui H,Wang JL,Wei LH

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Matrix metalloproteinase (MMP)-2 plays an important role in the remodeling of left ventricles (LVs) and right ventricles (RVs). We investigated the differences of MMP-2 expression between LV and RV in response to nandrolone decanoate (ND), swimming training (ST), and combined ND and ST (NS) in mice, based on...

journal_title：Chinese medical journal

authors： Bai Y,Shi XB,Zhang YQ,Wang YL,Liu XY,Esteve-Pastor MA

更新日期：2018-01-20 00:00:00

abstract：OBJECTIVE:The management strategies after acute myocardial infarction (AMI) have been evolving from simple supportive treatment to various protocols of thrombolytic therapies, and then to mechanical revascularization by balloon angioplasty in recent years. However, controversies still exist between which is the best tr...

journal_title：Chinese medical journal

authors： Lee SW,Chan HW,Lam L

更新日期：1997-06-01 00:00:00

abstract：OBJECTIVE:To study the clinicopathologic features and immunoprofile of angiomyofibroblastoma (AMF) with emphasis on differential diagnosis. METHODS:Seven vulvar, two vaginal and one perineal angiomyofibroblastomas were evaluated by light microscopy and immunohistochemistry. The immunohistochemical studies were perform...

journal_title：Chinese medical journal

authors： Wang J,Sheng W,Tu X,Shi D,Zhu X,Zhang R

更新日期：2000-11-01 00:00:00

abstract：OBJECTIVE:This review focuses on the role of the large conductance calcium-activated potassium (BKCa) channels in diabetic vascular complications. DATA SOURCES:Relevant articles published in English or Chinese from 1981 to present were selected from PubMed. The search terms were "BKCa channels" and "diabetes". Importa...

journal_title：Chinese medical journal

authors： Qian L,Liu X,Wang R

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Natural disasters have been frequent in recent years. Effective treatment of patients with cardiovascular disease following natural disasters is an unsolved problem. We aimed to develop a novel miniature mobile cardiac catheterization laboratory (Mini Mobile Cath Lab) to provide emergency interventional serv...

journal_title：Chinese medical journal

authors： Han YL,Liang Z,Yao TM,Sun JY,Liang M,Huo Y,Wang G,Wang XZ,Liang YC,Meng WH

更新日期：2012-03-01 00:00:00

abstract：:This review summarizes recent evidences regarding the potential influences of epidural labor analgesia (ELA) on the outcomes of neonates and children. Terms and relevant words including "ELA," "ELA and neonatal outcomes," "ELA and children's development," and "ELA and children's neurocognitive development" were used t...

journal_title：Chinese medical journal

authors： Liu ZH,Wang DX

更新日期：2020-10-05 00:00:00

abstract：OBJECTIVE:To observe the characteristics of coronary microvascular lesions (CML) in the autopsied elderly cases with hypertensive left ventricular hypertrophy (LVH) and the difference of CML among the groups of essential hypertension (EHT), coronary heart disease (CHD) and diabetes (NIDDM) also with LVH. METHODS:A ret...

journal_title：Chinese medical journal

authors： Li X,Li R,Yu W,Shi H,Wei L

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:As an X-linked recessive way, arginine vasopressin receptor 2 (AVPR2) gene mutation resulted in a hereditary disease - congenital nephrogenic diabetes insipidus (CNDI). We found a suspect clinical CNDI pedigree. In order to identify the genetic etiology, we performed the genetic analysis. METHODS:The clinic...

journal_title：Chinese medical journal

authors： Shen Y,Lai X,Xiao X,Li J,Yu R,Gao H,Zhang M

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Under conventional cytogenetic (CC) analysis, only 30% - 50% of B cell chronic lymphocytic leukemia (B-CLL) cases show clonal aberrations. Using fluorescence in situ hybridization (FISH), the percentage of patients with abnormalities rises to almost 80%, among them, the most frequent abnormalities were 13q14...

journal_title：Chinese medical journal

authors： Lai YY,Huang XJ

更新日期：2011-08-01 00:00:00