Role of BK(Ca) channels in diabetic vascular complications.

abstract：OBJECTIVE:To investigate the synergistic antitumor effects of combined use of p14ARF gene and 5-fluorouracil (5-Fu) in pancreatic cancer. METHODS:A human pancreatic cancer cell line PC-3 was transfected with lipofectin-mediated recombinant p14ARF gene, and was then administered with 5-Fu. Cell growth, morphological ch...

journal_title：Chinese medical journal

authors： Zhang Q,Ni Q,Gan J,Shen Z,Luo J,Jin C,Zhang N,Zhang Y

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Preconditioning with repeated electroacupuncture (EA) could mimic ischemic preconditioning to induce cerebral ischemic tolerance in rats. The present study was designed to investigate whether mu (micro)-, delta (delta)- or kappa (kappa)-opioid receptors are involved in the neuroprotection induced by repeated...

journal_title：Chinese medical journal

authors： Xiong LZ,Yang J,Wang Q,Lu ZH

更新日期：2007-03-05 00:00:00

abstract：BACKGROUND:Optical coherence tomography (OCT) is a high resolution noncontact imaging modality which can quantitatively detect the optic disc and retinal structure. This study was designed to evaluate the diagnostic capability of parameters of the optic disc, retinal nerve fiber layer thickness, and ganglion cell compl...

journal_title：Chinese medical journal

authors： Fang Y,Pan YZ,Li M,Qiao RH,Cai Y

更新日期：2010-08-05 00:00:00

abstract：BACKGROUND:Since early December 2019, the 2019 novel coronavirus disease (COVID-19) has caused pneumonia epidemic in Wuhan, Hubei province of China. This study aimed to investigate the factors affecting the progression of pneumonia in COVID-19 patients. Associated results will be used to evaluate the prognosis and to f...

journal_title：Chinese medical journal

authors： Liu W,Tao ZW,Wang L,Yuan ML,Liu K,Zhou L,Wei S,Deng Y,Liu J,Liu HG,Yang M,Hu Y

更新日期：2020-05-05 00:00:00

abstract：BACKGROUND:Previous studies have suggested that primary degeneration of hair cells causes secondary degeneration of spiral ganglion neurons (SGNs), but the effect of SGN degeneration on hair cells has not been studied. In the adult mouse inner ear ouabain can selectively and permanently induce the degeneration of type ...

journal_title：Chinese medical journal

authors： Yuan Y,Chi F

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To review the relationship between personal behavior and cultural factors and reproductive tract infections (RTIs). METHODS:An English-language literature search using MEDLINE (1994-1998), Social Science Index (1994-1998), and informal discovery. Any original researches and reviews related to RTIs' epidemiol...

journal_title：Chinese medical journal

authors： Guo S

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND:Hirayama disease is a rare disease characterized by juvenile-onset of asymmetric amyotrophy, of which etiology has not been clarified. The aim of our study was to investigate the clinical and neurophysiologic characteristics of Hirayama disease. METHODS:Neurophysiological tests, including nerve conduction s...

journal_title：Chinese medical journal

authors： Wang XN,Cui LY,Liu MS,Guan YZ,Li BH,DU H

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Although obstructive sleep apnea (OSA) has been recognized as a major risk factor for cardiovascular complications and its clinical features are well characterized, it is difficult to replicate the OSA hypoxic model in humans. We aimed to establish an experimental rabbit model for chronic OSA and to explore ...

journal_title：Chinese medical journal

authors： Xu LF,Zhou XF,Hu K,Tang S,Luo YC,Lu W

更新日期：2017-02-20 00:00:00

abstract：:Cellular and humoral immune functions in Chinese hemophiliacs with and without human immunodeficiency virus (HIV) infection were compared with those of healthy controls. There was a significant increase in peripheral T8 cells and a significant decrease of peripheral T4 cells as well as the T4/T8 ratio in 3 hemophiliac...

journal_title：Chinese medical journal

authors： Tang DJ,Pang XG

更新日期：1991-10-01 00:00:00

abstract：OBJECTIVE:To understand the relationship among congenital choledochal cyst, anomalous junction of pancreaticobiliary duct (AJPBD) and pancreatitis. METHODS:25 children with choledochal cyst treated in our hospital were included in this study. Their ages ranged from 2 months to 14 years. Intraoperative cholangiography ...

journal_title：Chinese medical journal

authors： Zhao L,Li Z,Ma H,Zhang X,Mou X,Zhang D,Lin W,Niu A

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:Susceptibility to coronary artery disease (CAD) and diabetes is encoded by distinct, tightly-linked single nucleotide polymorphisms on chromosome 9p21. This study aimed to examine the association of variant rs1333049 on chromosome 9p21.3 with early-onset and severity of CAD in Chinese patients with and witho...

journal_title：Chinese medical journal

authors： Wang W,Peng WH,Lu L,Zhang RY,Zhang Q,Wang LJ,Chen QJ,Shen WF

更新日期：2011-01-01 00:00:00

abstract：:Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. The heart is one of the most important oxygen delivery organs, and dysfunction significantly increases the mortality of the body. Hence, the heart has been studied in sepsis for over half a century. However, th...

journal_title：Chinese medical journal

authors： Wang J,Wang XT,Liu DW,Zhang HM,Su LX

更新日期：2020-09-20 00:00:00

abstract：BACKGROUND:There are few reports of microsurgical treatment of dorsum sellae meningiomas-which, because of location, size, and differences in growth direction, clinical presentations, degree of surgical difficulty, have varied posttreatment sequelae. In pursuit of an optimal microsurgical treatment option for dorsum se...

journal_title：Chinese medical journal

authors： Geng SM,Zhang JT,Zhang LW,Wu Z,Wang ZC

更新日期：2009-08-20 00:00:00

abstract：OBJECTIVE:To study the pharmacodynamics of vecuronium,atracurium, mivacurium and rocuronium in patients with end-stage renal failure. METHODS:Forty-six patients with end-stage renal failure scheduled for renal transplantation and 53 patients with normal renal function were given either vecuronium, atracurium, mivacuri...

journal_title：Chinese medical journal

authors： Ma H,Zhuang X

更新日期：2002-11-01 00:00:00

abstract：:Of 40 patients with cervical spine tumor treated from 1980 to 1990, 24 had a primary tumor and 16 a metastatic tumor. Thirty-four patients were operated on through anterior and 5 through posterior approach. Preoperative neck pain was relieved and muscular strength of shoulder and arm increased after operation. Total e...

journal_title：Chinese medical journal

authors： Liu HK,Liu ZD

更新日期：1992-07-01 00:00:00

abstract：Background:Facing the increasing prevalence of gestational diabetes mellitus (GDM), this study aimed to evaluate the management of GDM and its association with adverse pregnancy outcomes. Methods:The data of 996 inpatients with GDM who terminated pregnancies in our hospital from January 2011 to December 2015 were coll...

journal_title：Chinese medical journal

authors： Feng R,Liu L,Zhang YY,Yuan ZS,Gao L,Zuo CT

更新日期：2018-05-05 00:00:00

abstract：BACKGROUND:The Dynamic Interspinous Assisted Motion (DIAM) system was designed to stabilize degenerative spinal segments without fusion surgery, maintain segment motion and prevent adjacent segment degeneration. The aim of this study was to investigate clinical efficacy of the DIAM system in treatment of degenerative l...

journal_title：Chinese medical journal

authors： Zhao Y,Wang YP,Qiu GX,Zhao H,Zhang JG,Zhou X

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Osteoarthritis (OA) is the most common form of human polyarthritis. Many genetic factors have been implicated in OA. It was reported that a polymorphism in the gene of interleukin-6 (IL-6) was associated with OA of knee. The aim of this study was to determine whether functional IL-6 promoter -174G/C (rs18007...

journal_title：Chinese medical journal

authors： Ai Z,Ning X,Shou T,Tang W,Luo Y,Zhang J

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:There are no conclusive studies evaluating the interaction between icariin and exercise for treatment of osteoporosis; the efficacy and safety of this treatment combination remains to be evaluated. The purpose of this study was to investigate the effects of icariin treatment combined with exercise therapy on...

journal_title：Chinese medical journal

authors： Liu M,Zhong C,He RX,Chen LF

更新日期：2012-05-01 00:00:00

abstract：:Psoralen (PSO) was found cytotoxic against in vitro cultured human mucoepidermoid carcinoma cells of MEC-1 cell line. Its IC50 value was 8.6 micrograms/ml, and relative antitumor activity (RAA) 15. PSO suppressed DNA synthesis, damaged microvilli and cell membrane, and induced degeneration of mitochondria. It inhibite...

journal_title：Chinese medical journal

authors： Wu JZ,Situ ZQ,Wang W,Chen JY,Liu B

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:Sacroiliac (SI) screw fixation is a demanding technique, with a high rate of screw malposition due to the complex pelvic anatomy. TiRobot™ is an orthopedic surgery robot which can be used for SI screw fixation. This study aimed to evaluate the accuracy of robot-assisted placement of SI screws compared with a...

journal_title：Chinese medical journal

authors： Wang JQ,Wang Y,Feng Y,Han W,Su YG,Liu WY,Zhang WJ,Wu XB,Wang MY,Fan YB

更新日期：2017-11-05 00:00:00

abstract：:Type 2 diabetes mellitus and metabolic disorders have become an epidemic globally. However, the pathogenesis remains largely unclear and the prevention and treatment are still limited. In addition to environmental factors during adulthood, early life is the critical developmental window with high tissue plasticity, wh...

journal_title：Chinese medical journal

authors： Zhou LY,Deng MQ,Zhang Q,Xiao XH

更新日期：2020-08-20 00:00:00

abstract：BACKGROUND:The gradually increasing changes in a human hyperlipidemic diet along with chronic stress might play an important role in the increased numbers of fatty liver. This study investigated the effects of Ilex asprella root decoction on related genes of lipid metabolism in chronic stress in hyperlipidemic fatty li...

journal_title：Chinese medical journal

authors： Hu XY,Shu XC,Guo Y,Ma Y

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) is a rare but potentially life-threatening congenital heart defect. A retrospective analysis was carried out to elucidate the surgical outcomes of ALCAPA in infants and children using follow-up echocardiography. METHODS:From Sep...

journal_title：Chinese medical journal

authors： Gao Y,Zhang J,Huang GY,Liang XC,Jia B,Ma XJ

更新日期：2017-10-05 00:00:00

abstract：OBJECTIVE:To analyze the effect and mechanism of hyperbaric oxygen (HBO) treatment for severe brain injury (SBI). METHODS:Fifty-five patients were divided into a treatment group of 35 patients and a control group of 20 patients. We observed the alterations of clinical, brain electric earth map (BEAM), endothelin (ET) ...

journal_title：Chinese medical journal

authors： Ren H,Wang W,Ge Z,Zhang J

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:Serum antinuclear antibodies (ANAs) are positive in some patients with chronic lymphocytic leukemia (CLL), but the prognostic value of ANAs remains unknown. The aim of this study was to evaluate the role of ANAs as a prognostic factor in CLL. METHODS:This study retrospectively analyzed clinical data from 21...

journal_title：Chinese medical journal

authors： Sun Q,Wang L,Zhu HY,Miao Y,Wu W,Liang JH,Cao L,Xia Y,Wu JZ,Wang Y,Wang R,Fan L,Xu W,Li JY

更新日期：2019-03-05 00:00:00

abstract：BACKGROUND:As an X-linked recessive way, arginine vasopressin receptor 2 (AVPR2) gene mutation resulted in a hereditary disease - congenital nephrogenic diabetes insipidus (CNDI). We found a suspect clinical CNDI pedigree. In order to identify the genetic etiology, we performed the genetic analysis. METHODS:The clinic...

journal_title：Chinese medical journal

authors： Shen Y,Lai X,Xiao X,Li J,Yu R,Gao H,Zhang M

更新日期：2014-01-01 00:00:00

abstract：:Myocardial revascularization by Nd: YAG laser used in rats with myocardial infarction was studied. The left coronary artery was ligated and the laser channels with a diameter of 300 microns were made immediately by 2.5-4.2 W lasersonics YAG unit. After 24 hours, the rats were killed. Evaluation included hemodynamics, ...

journal_title：Chinese medical journal

authors： Guo JX,Pan J,Ma L,Chen MZ,Xu H,Shi AY

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND:A simple, safe and effective therapeutic strategy for traumatic instability of the subaxial cervical spine, as well as its prognostic assessment, is still controversial. METHODS:The therapeutic options for 83 patients of traumatic instability of the subaxial cervical spine, whose average age was 35 years, w...

journal_title：Chinese medical journal

authors： Cao P,Liang Y,Gong YC,Zheng T,Zhang XK,Wu WJ

更新日期：2008-08-05 00:00:00

abstract：: ...

journal_title：Chinese medical journal

authors： Du Y,Zhao YX,Liu W,Zhang JW,Yan ZX,Zhou YJ

更新日期：2018-11-20 00:00:00