Abstract：
BACKGROUND:Morphologic imaging after radiofrequency ablation (RFA) of liver metastases is hampered by an inflammatory response in the ablation margin, making the identification of local tumor progression (LTP) difficult. The aim of this study was to evaluate the efficacy of early (18)F-FDG PET/CT scanning to monitor the effectiveness of RFA in colorectal liver metastases. METHODS:Twelve patients with 20 metastases were treated with RFA for colorectal liver metastases. They underwent PET/CT within 2 weeks before RFA and within 24 hours after RFA (so termed "early PET/CT"). PET/CT was repeated at 1, 3, and 6 months, and then every 6 months after ablation. The standard of reference was based on available clinical and radiological follow-up data. RESULTS:Early PET/CT revealed total photopenia in 16 RFA-treated metastases, which were found to be without residual tumor on the final PET/CT scan. Three RFA-treated metastases with focal uptake were identified as local tumor progression, which necessitated further treatment. One RFA-treated metastasis with rim-shaped uptake was regarded as inflammation. The results of the early PET/CT scanning were consistent with the findings of the final follow-up. CONCLUSIONS:PET/CT performed within 24 hours after RFA can effectively detect whether residual tumor exists for colorectal cancer liver metastases. The results can guide further treatment, and may improve the efficacy of RFA.
journal_name
Chin Med J (Engl)journal_title
Chinese medical journalauthors
Liu ZY,Chang ZH,Lu ZM,Guo QYsubject
Has Abstractpub_date
2010-07-01 00:00:00pages
1690-4issue
13eissn
0366-6999issn
2542-5641journal_volume
123pub_type
杂志文章abstract：BACKGROUND:In county-level tuberculosis (TB) dispensaries in China, the accurate diagnosis of sputum smear-negative pulmonary tuberculosis (SNPT) needs to be improved by developing and validating clinical and radiographic predictors. METHODS:The study was conducted simultaneously in three counties per province in Chon...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
更新日期：2013-01-01 00:00:00
abstract：OBJECTIVE:To observe the characteristics of coronary microvascular lesions (CML) in the autopsied elderly cases with hypertensive left ventricular hypertrophy (LVH) and the difference of CML among the groups of essential hypertension (EHT), coronary heart disease (CHD) and diabetes (NIDDM) also with LVH. METHODS:A ret...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
更新日期：2002-05-01 00:00:00
abstract：:T cell subsets in peripheral blood were phenotyped in 56 patients with different stages of Schistosomiasis japonica, including 17 with acute, 14 with chronic and 25 with advanced infection. The activity of interleukin-1 (IL-1) produced by peripheral blood mononuclear cells (PBMC) induced by lipopolysaccharide (LPS) in...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
更新日期：1993-03-01 00:00:00
abstract：BACKGROUND:Fractional flow reserve (FFR) has become an increasingly important index when making decisions with respect to revascularization of coronary artery stenosis. However, the pressure guidewire used in obtaining FFR measurements is difficult to control and manipulate in certain complex coronary artery lesions, r...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：10.4103/0366-6999.152664
更新日期：2015-03-20 00:00:00
abstract：BACKGROUND:It remains controversial whether patients with Stage II colorectal cancer would benefit from adjuvant chemotherapy after radical resection. The aim of this study was to establish two mathematical models to identify the suitable patients for adjuvant chemotherapy. METHODS:The current study comprised of two s...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：10.4103/0366-6999.213432
更新日期：2017-09-05 00:00:00
abstract：BACKGROUND:Pancreatic cancer is a highly malignant tumor affecting an ever increasing number of patients with a mean 5-year survival rate below 4%. Therefore, gene therapy for cancer has become a potential novel therapeutic modality. In this study we sought to determine the inhibitory effects of adenovirus-mediated hum...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
更新日期：2008-10-20 00:00:00
abstract：BACKGROUND:The decreased degradation of extra-cellular matrix proteins plays an important role in the onset of diabetic nephropathy. Matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of metalloproteinase-1 (TIMP-1), which are members of the matrix metalloproteinase family, are associated with this process. Angiot...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
更新日期：2007-11-05 00:00:00
abstract：BACKGROUND:Retinol binding protein 4 (RBP4), as an adipocyte secreted cytokine, was recently found to be inversely correlated with expression of glucose transporter 4 (GLUT4) in insulin resistance (IR) state and to have an intimate relationship with IR and type 2 diabetes mellitus (T2DM). The present study aimed to eva...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
更新日期：2008-11-05 00:00:00
abstract：OBJECTIVE:To investigate the occurrence and extent of apoptosis in the course of restenosis. METHODS:The experimental models of vessel narrowness and intima thickness were established in minipigs' iliac arteries by balloon injury and specimens were retrieved on the 1st, 3rd, 6th, 12th and 30th days for dynamic observa...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：BACKGROUND:Although transient ischemic attacks (TIA) is a clinical diagnosis, imaging findings are important for its diagnosis and treatment. This study evaluated the value and limitations of conventional CT, CT cerebral perfusion imaging and transcranial Doppler sonography (TCD) in patients with TIA. METHODS:Conventi...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
更新日期：2005-11-05 00:00:00
abstract：PURPOSE:To review the current status of multimodality treatment and lymphadenectomy in the management of esophageal cancer. DATA SOURCES:Literature review. STUDY SELECTION:Multimodality treatment and lymphadenectomy in esophageal cancer. DATA EXTRACTION:Results in research papers published selected by literature sea...
journal_title：Chinese medical journal
pub_type： 杂志文章,评审
doi：
更新日期：1997-11-01 00:00:00
abstract：OBJECTIVE:To study if the functions of C gene and its promotor are related to the pathogenesis of hepatitis B and to describe their hot spot mutations in Chinese patients. DATA SOURCES:We have studied this subject in recent years. A mini-review is based on some unpublished works. DATA SELECTION:The sequence data of C...
journal_title：Chinese medical journal
pub_type： 杂志文章,评审
doi：
更新日期：1999-02-01 00:00:00
abstract：:Endolymphatic sac papillary tumor (ELST) is an extremely rare and aggressive tumor characterized by hearing loss and temporal bone destruction. A case with clinical, imaging, pathologic and treatment data is reported and relevant literature is reviewed. A 25-year-old woman, with ELST underwent craniotomy for tumor sub...
journal_title：Chinese medical journal
pub_type： 杂志文章,评审
doi：
更新日期：2011-11-01 00:00:00
abstract：:Serial cerebrospinal fluid immunoglobulin parameters were determined with the method of single radial immunodiffusion in 419 cases of 20 kinds of neurological diseases. The results were compared with the normal values of 36 subjects of corresponding ages and statistically analyzed. The authors believe that the elevate...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
更新日期：1989-03-01 00:00:00
abstract：BACKGROUND:Generalized glucocorticoid resistance syndrome is a rare familial or sporadic condition characterized by generalized, partial, target-tissue insensitivity to glucocorticoids. This syndrome is partially caused by mutations in the human glucocorticoid receptor (hGR) gene. The clinical spectrum of generalized g...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
更新日期：2011-02-01 00:00:00
abstract：BACKGROUND:The emergence of bacterial resistance to commonly used antibiotics, such as macrolides, is complicating the management of respiratory tract infections (RTIs). Telithromycin, a ketolide antimicrobial structurally related to macrolides, is approved for the treatment of community-acquired RTIs, and shows lower ...
journal_title：Chinese medical journal
pub_type： 杂志文章,meta分析
doi：
更新日期：2013-01-01 00:00:00
abstract：BACKGROUND:Phosphorous magnetic resonance spectroscopy ((31)P-MRS) has been successfully applied to study intracellular membrane compounds and high-energy phosphate metabolism. This study aimed to evaluate the capability of dynamic (31)P-MRS for assessing energy metabolism and mitochondrial function in skeletal muscle ...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
更新日期：2012-01-01 00:00:00
abstract：OBJECTIVE:To study the severe acute respiratory syndrome (SARS)-associated coronavirus genotype and its characteristics. METHODS:A SARS-associated coronavirus isolate named ZJ01 was obtained from throat swab samples taken from a patient in Hangzhou, Zhejing province. The complete genome sequence of ZJ01 consisted of 2...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
更新日期：2003-09-01 00:00:00
abstract：OBJECTIVE:To investigate the efficacy of continuous renal replacement therapy (CRRT) versus intermittent hemodialysis (IHD) in patients with severe acute renal failure (ARF). METHODS:One hundred and ninety-three severe ARF patients who received renal support between December 1978 and December 1998 were involved in thi...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
更新日期：2001-11-01 00:00:00
abstract：BACKGROUND:Although there are several drugs and drug combinations for the treatment of Pneumocystis carinii (P. carinii) pneumonia, all drugs have the toxicity as well as low efficacy. Iron chelators have been proposed as a source of new drugs for combating these infections. We hypothesized that iron chelators would su...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
更新日期：2004-11-01 00:00:00
abstract：:In 123 cases of transient ischemic attacks, 72 were followed up for 22 years. The percentage of complete stroke was 46.5% and the fatality rate 47.9%. Causes of death, survival rate by life table, limitation of indication of neurovascular surgical operation and rehabilitation of survived patients were studied. The cau...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
更新日期：1990-09-01 00:00:00
abstract：BACKGROUND:T8590C polymorphism of CYP4A11 has been associated with hypertension, though with conflicting results. The aim of this study was to quantitatively summarize the evidence for CYP4A11 T8590C polymorphism and hypertension risk. METHODS:Electronic search of PubMed and the Chinese Biomedicine database was conduc...
journal_title：Chinese medical journal
pub_type： 杂志文章,meta分析
doi：
更新日期：2014-01-01 00:00:00
abstract：BACKGROUND:One of the reasons for poor neuroregeneration after central nervous system injury is the presence of inhibitory factors such as Nogo. Here, we tested the inhibition of Nogo by RNA interference both in vitro and in vivo, using recombinant adenovirus-mediated transfection of short hairpin RNAs, to explore a ne...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
更新日期：2012-11-01 00:00:00
abstract：BACKGROUND:Volatile anesthetics (VAs) may affect varied and complex physiology processes by manipulating Ca(2+)-calmodulin (CaM). However, the detailed mechanism about the action of VAs on CaM has not been elucidated. This study was undertaken to examine the effects of VAs on the conformational change, hydrophobic site...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
更新日期：2012-09-01 00:00:00
abstract：BACKGROUND:Insulin-like growth factor-II mRNA-binding protein 3 (IMP3) is a newly identified mRNA-binding protein that is involved in embryogenesis and carcinogenesis of some malignant tumors. The aim of this study was to detect the expression of IMP3 protein in gastric adenocarcinoma (GAC) and the correlation with cli...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
更新日期：2010-12-01 00:00:00
abstract：Background:Development of innovative immunotherapy is imperative to improve the poor survival of the nasopharyngeal carcinoma (NPC) patients. In this study, we evaluated the T cell response to melanoma-associated antigen (MAGE)-A1, MAGE-A3, or synovial sarcoma X-2 (SSX-2) in the peripheral blood of treatment-naive NPC ...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：10.4103/0366-6999.232791
更新日期：2018-06-05 00:00:00
abstract：BACKGROUND:The aim of this research was to analyze the perioperative factors of regular hepatectomy and irregular hepatectomy. The superiority of the clinical application of the two methods was compared in the perioperative period. METHODS:From 1986 to 2011, 1798 patients underwent consecutive liver resections with re...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
更新日期：2014-01-01 00:00:00
abstract：OBJECTIVE:To investigate molecular events of exocytosis in cultured human pheochromocytoma cells with stimulation. METHODS:The cultured pheochromocytoma cells prepared from human adrenal pheochromocytoma tumor were stimulated for the release of catecholamines by depolarization with the administration of 50 mmol/L KCl....
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
更新日期：1998-04-01 00:00:00
abstract：BACKGROUND:Hospital-acquired pneumonia (HAP) is the most common hospital-acquired infection in China with substantial morbidity and mortality. But no specific risk assessment model has been well validated in patients with HAP. The aim of this study was to investigate the published risk assessment models that could pote...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：10.1097/CM9.0000000000001252
更新日期：2020-12-03 00:00:00
abstract：BACKGROUND:Borderline gastrointestinal stromal tumors (GISTs) are intermediate tumors between benign and malignant variants; however, the clinical and pathological features of borderline GISTs remain poorly defined. This study aimed to characterize GISTs and to identify a set of borderline criteria for practical use. ...
journal_title：Chinese medical journal
pub_type： 杂志文章
doi：
更新日期：2010-09-01 00:00:00
