Upregulation of drug sensitivity of multidrug-resistant SGC7901/VCR human gastric cancer cells by bax gene transduction.

abstract：OBJECTIVE:To investigate the occurrence and extent of apoptosis in the course of restenosis. METHODS:The experimental models of vessel narrowness and intima thickness were established in minipigs' iliac arteries by balloon injury and specimens were retrieved on the 1st, 3rd, 6th, 12th and 30th days for dynamic observa...

journal_title：Chinese medical journal

authors： Huang J,Yin H,Leng J,Yao Y,Yao R,Peng T,Li J

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Orthostatic intolerance (OI) is a common disease at pediatric period which has a serious impact on physical and mental health of children. The purpose of this study was to investigate the effect of related factors on the prognosis of children with OI. METHODS:The subjects were 170 children with OI, includin...

journal_title：Chinese medical journal

authors： Li Y,Li H,Li X,Li X,Jin H

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To study the clinicopathologic features and immunoprofile of angiomyofibroblastoma (AMF) with emphasis on differential diagnosis. METHODS:Seven vulvar, two vaginal and one perineal angiomyofibroblastomas were evaluated by light microscopy and immunohistochemistry. The immunohistochemical studies were perform...

journal_title：Chinese medical journal

authors： Wang J,Sheng W,Tu X,Shi D,Zhu X,Zhang R

更新日期：2000-11-01 00:00:00

abstract：:To investigate the HBV infection and its replication in Chinese patients with chronic liver disease, polymerase chain reaction (PCR) was employed to detect hepatitis B virus DNA in sera of 410 patients with chronic liver disease and liver samples from 188 patients. The HBV DNA detectability in all serum samples was 58...

journal_title：Chinese medical journal

authors： Zhang YY,Guo LS,Li L,Zhang YD,Hao LJ,Hansson BG,Nordenfelt E

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Prediabetes is an early stage of β-cell dysfunction presenting as insulin resistance. Evidences suggest that endoplasmic reticulum (ER) stress is involved in the pathogenesis of type 2 diabetes mellitus and prediabetes. In a Chinese population with prediabetes, we investigated single nucleotide polymorphisms...

journal_title：Chinese medical journal

authors： Feng N,Ma X,Wei X,Zhang J,Dong A,Jin M,Zhang H,Guo X

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Using tissue Doppler imaging and conventional echocardiographic technique, we examined the cardiac function and synchronicity in individuals with isolated right bundle branch block (RBBB) or left bundle branch block (LBBB) and assessed the relationship between QRS duration and synchronicity. METHODS:Subject...

journal_title：Chinese medical journal

authors： Niu HX,Hua W,Zhang S,Sun X,Wang FZ,Chen KP,Wang H,Chen X

更新日期：2006-05-20 00:00:00

abstract：OBJECTIVE:To explore the mechanism of autoimmune hemolysis and establish a more sensitive test for autoimmune hemolytic anemia (AIHA). METHODS:IgG subclasses were tested in 40 patients with idiopathic or secondary AIHA by Coombs test with monoclonal antibodies. Hb, TBil, RC and FHb, as hemolytic parameters, were used ...

journal_title：Chinese medical journal

authors： Li Z,Shao Z,Xu Y,Shen L,Chen G,Zhang Y,Chu Y

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND:It has been proved that sevoflurane postconditioning (SpostC) could protect the heart against myocardial ischemia/reperfusion injury, however, there has been few research focused on the electrophysiological effects of SpostC. The objective of the study was to investigate the effects of SpostC on action poten...

journal_title：Chinese medical journal

authors： Gong JS,Yao YT,Fang NX,Huang J,Li LH

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVE:To study the analgesic mechanism of gabapentin, an anticonvulsant, during antinociceptive clinical treatment. METHODS:Whole-cell voltage-clamp recordings were taken from adult rat spinal cord slices to investigate the effect of gabapentin on primary afferent A delta-fiber evoked excitatory postsynaptic curre...

journal_title：Chinese medical journal

authors： Liu Z,Xu R,Yang K

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:Psoriasis is a chronic inflammatory skin disease, affecting about 0.6% of the Chinese population. Many patients are not well controlled by conventional treatments, thus there is need for new treatment regimens. In this study, we assessed the efficacy and safety of secukinumab in Chinese patients with moderat...

journal_title：Chinese medical journal

authors： Cai L,Zhang JZ,Yao X,Gu J,Liu QZ,Zheng M,Zhang SF,Xu JH,Li CX,Cheng H,Guo Q,Pan WL,Li SQ,Li RY,Guo ZP,Song ZQ,Li SS,Dong XQ,Wang L,Fu R,Regnault P,Charef P,Mazur R,Patekar M

更新日期：2020-11-20 00:00:00

abstract：BACKGROUND:Aerosolized amikacin (AA) is a current option for the management of ventilator-associated pneumonia (VAP) caused by multidrug-resistant Gram-negative bacteria (MDR-GNB), as it is reported that AA could increase the alveolar level of the drug without increasing systemic toxicity. This study aimed to evaluate ...

journal_title：Chinese medical journal

authors： Liu C,Zhang YT,Peng ZY,Zhou Q,Hu B,Zhou H,Li JG

更新日期：2017-05-20 00:00:00

abstract：BACKGROUND:Phosphorous magnetic resonance spectroscopy ((31)P-MRS) has been successfully applied to study intracellular membrane compounds and high-energy phosphate metabolism. This study aimed to evaluate the capability of dynamic (31)P-MRS for assessing energy metabolism and mitochondrial function in skeletal muscle ...

journal_title：Chinese medical journal

authors： Wu FY,Tu HJ,Qin B,Chen T,Xu HF,Qi J,Wang DH

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:A correct thyroid function reference range is important for the accurate diagnosis of thyroid disease during pregnancy. However, there is no consensus on whether thyroid function reference ranges in Chinese population should follow the America Thyroid Association (ATA) guidelines. This study aimed to establi...

journal_title：Chinese medical journal

authors： Yang X,Meng Y,Zhang Y,Zhang C,Guo F,Yang S,Ding R,Fan JX

更新日期：2019-03-05 00:00:00

abstract：BACKGROUND:Aquaporin-1 (AQP1) has involved in fluid transport in diverse pulmonary edema diseases. Our study aimed to explore the dynamic changes of AQP1 in pulmonary water metabolism in rats following traumatic brain injury (TBI) and the protective effect provided by shenmai injection. METHODS:Sixty male Sprague Dawl...

journal_title：Chinese medical journal

authors： Bai Y,Yao HX,Hu ML,Wang LR,Jin LD,Wang WT,Lin LN

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Several difficulties can arise from wide-neck cerebral aneurysms when treated with endovascular embolization. We aimed to investigate the effect of endovascular treatment of intracranial aneurysms using coil embolization plus an Enterprise stent. METHODS:Forty patients were treated with coil embolization pl...

journal_title：Chinese medical journal

authors： Xu X,Shang XM,Cui JZ,Wang DY

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Hospital-acquired pneumonia (HAP) is the most common hospital-acquired infection in China with substantial morbidity and mortality. But no specific risk assessment model has been well validated in patients with HAP. The aim of this study was to investigate the published risk assessment models that could pote...

journal_title：Chinese medical journal

authors： Wen JN,Li N,Guo CX,Shen N,He B

更新日期：2020-12-03 00:00:00

abstract：BACKGROUND:Endovenous laser ablation (EVLA) is an improved method to treat varicose great saphenous veins (GSV) with a high satisfactory rate. This study aimed to evaluate the efficiency and safety of treatment by EVLA procedures with ultrasound-guided perivenous tumescence. METHODS:Thirty-one patients (31 limbs) with...

journal_title：Chinese medical journal

authors： Chen JQ,Xie H,Deng HY,Yuan K,Zhang JW,Zhang H,Zhang L

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVE:To choose one optimal extrinsic positive end-expiratory pressure (PEEPe) for ventilated patients with chronic obstructive pulmonary disease (COPD) and to compare two methods for choosing the optimal level of PEEPe. METHODS:Ten ventilated patients with COPD were included in the study. First, static intrinsic ...

journal_title：Chinese medical journal

authors： Kong W,Wang C,Yang Y,Huang K,Jiang C

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:Respiratory syncytial virus (RSV) is a common pathogen in the lower respiratory tract of infants and children. Recent studies have shown that in adults, especially in the elderly population who have relatively weak immunity, lower respiratory tract infection is not uncommon. RSV was detected in 22% hospitali...

journal_title：Chinese medical journal

authors： Li W,Shen HH

更新日期：2007-01-05 00:00:00

abstract：:Percutaneous balloon mitral valvuloplasty (PBMV) was successfully performed in 50 selected patients with mitral stenosis by using Inoue pillow-shaped balloon and Inoue technique. The average diameter of balloon used was 26.9 +/- 0.9 mm. 90% (45/50) of cases had either double or single mitral commissura split. Of the r...

journal_title：Chinese medical journal

authors： Fang WY,Yu WX,Lu ZX,Li XM,Bu DX,Xu WL

更新日期：1994-09-01 00:00:00

abstract：:After cis-diamminedichloroplatinum ethylcellulose microcapsules (CDDPmc) and unencapsulated CDDP were infused into the hepatic arteries of New Zealand rabbits, both CDDP concentrations in the circulating blood and in hepatic tissue were measured at different time intervals. In the rabbits infused with CDDPmc, the CDDP...

journal_title：Chinese medical journal

authors： Wang Y,Wu MC,Zhang XH

更新日期：1992-02-01 00:00:00

abstract：OBJECTIVE:To review the origin, diagnosis, treatment and public health concern of New Delhi metallo-β-lactamase (NDM)-producing bacteria. DATA SOURCES:We searched database for studies published in English. The database of PubMed from 2007 to 2015 was used to conduct a search using the keyword term "NDM and Acinetobact...

journal_title：Chinese medical journal

authors： Wei WJ,Yang HF,Ye Y,Li JB

更新日期：2015-07-20 00:00:00

abstract：BACKGROUND:Over 70% of the total tissue weight in the cartilage matrix consists of water, and the early-stage osteoarthritic cartilage is characterized by swelling. Water transport in the cartilage matrix and across the membranes of chondrocytes may be important in normal and pathological conditions of cartilage. The p...

journal_title：Chinese medical journal

authors： Meng JH,Ma XC,Li ZM,Wu DC

更新日期：2007-12-20 00:00:00

abstract：:131 cases of epidemic hepatitis from two villages in Xinjiang, were admitted to the provisional infectious diseases hospital from February to April 1987. In 125 (95%) patients neither anti-HAV IgM nor anti-HBc IgM were positive. 118 (90%) were drinking water from a local stream of the Hotan River. The study was conduc...

journal_title：Chinese medical journal

authors： Wang XC,Liu XM,Tan CZ,Liu R,Luo SL,Yue XH,Qin F,Bu ZR,Tian X,Song DY

更新日期：1990-11-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of red orpiment on cell morphology, expression of promyelocytic leukemia (PML) mRNA and its protein localization in NB4 and HL-60 cell lines. METHODS:Cell morphology was assayed by Wright's staining and fluorescence staining, while PML mRNA expression was determined by RT-PCR. PML ...

journal_title：Chinese medical journal

authors： Zhong L,Chen F,Han J,Shao N,Ouyang R

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:To investigate the efficacy of continuous renal replacement therapy (CRRT) versus intermittent hemodialysis (IHD) in patients with severe acute renal failure (ARF). METHODS:One hundred and ninety-three severe ARF patients who received renal support between December 1978 and December 1998 were involved in thi...

journal_title：Chinese medical journal

authors： Ji D,Gong D,Xie H,Xu B,Liu Y,Li L

更新日期：2001-11-01 00:00:00

abstract：:The solid pseudopapillary tumors of the pancreas (SPTP) are rare tumors, which are commonly found in adolescent women. Radical surgical resection of the primary tumor or metastases is the standard treatment for SPTP and could achieve long-term survival. We reported a case of a 20-year-old female with multiple liver me...

journal_title：Chinese medical journal

authors： Li JX,Wu H,Huang JW,Prasoon P,Zeng Y

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Stereotactic radiosurgery is an alternative to resection of intracranial cerebral arteriovenous malformations (AVMs), while it will fail in some cases. This study aimed to evaluate the changes after stereotactic radiosurgery for AVMs. METHODS:Nineteen cases with cerebral AVMs had failure after stereotactic ...

journal_title：Chinese medical journal

authors： Liu WM,Ye X,Zhao YL,Wang S,Zhao JZ

更新日期：2008-06-20 00:00:00

abstract：BACKGROUND:Cigarette smoke induces an acute but persisting inflammation in peripheral blood and airway in chronic obstructive pulmonary disease (COPD), and CD8(+) Tc-lymphocytes are considered as a key role in this process. We aimed to investigate the Tc-lymphocytes immunodeviation in system and local airway of COPD pa...

journal_title：Chinese medical journal

authors： Yu MQ,Liu XS,Wang JM,Xu YJ

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Precise evaluation of the live donor's liver is the most important factor for the donor's safety and the recipient's prognosis in living donor liver transplantation (LDLT). Our study assessed the clinical value of computer-assisted three-dimensional quantitative assessment and a surgical planning tool for do...

journal_title：Chinese medical journal

authors： Wei L,Zhu ZJ,Lü Y,Jiang WT,Gao W,Zeng ZG,Shen ZY

更新日期：2013-04-01 00:00:00