解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::The vulva can be affected by a variety of sexually transmitted infections as well as other common infections that are not typically related to sexual transmission. Vulvar infections may adversely affect the quality of life of the patients by causing discomfort and pain. Some of these infections, especially the ulcerat...
journal_title:Seminars in diagnostic pathology
pub_type: 杂志文章,评审
doi:10.1053/j.semdp.2020.09.012
更新日期:2021-01-01 00:00:00
abstract::Various types of lymphoid neoplasms can occur in the lung. Lung parenchyma, the pleura or the pleural cavity can be the primary site of a lymphoid neoplasm or can be involved secondarily as a result of systemic dissemination from a separate primary site. Recognition of pulmonary lymphoid neoplasms (PLN) has increased ...
journal_title:Seminars in diagnostic pathology
pub_type: 杂志文章,评审
doi:10.1053/j.semdp.2020.06.006
更新日期:2020-11-01 00:00:00
abstract::Hematopoietic neoplasms involving the spleen are uncommon, but T cell neoplasms involving the spleen are extremely rare. The rarity of splenic involvement by T cell neoplasms has resulted in a limited body of literature describing their splenic characteristics. As a result, our purpose in this review article is to pro...
journal_title:Seminars in diagnostic pathology
pub_type: 杂志文章,评审
doi:10.1053/j.semdp.2020.10.001
更新日期:2020-10-09 00:00:00
abstract::The identification and proper characterization of pathologic renal intratubular casts can be an arduous task, especially since they often admixed with non-pathologic casts, obfuscating debris and inflammation. The list of pathologic intratubular casts is long, and they can be easily missed or misdiagnosed without a th...
journal_title:Seminars in diagnostic pathology
pub_type: 杂志文章,评审
doi:10.1053/j.semdp.2020.02.001
更新日期:2020-05-01 00:00:00
abstract::Mature T-cell and NK-cell leukemias represent a clinically heterogeneous group of diseases, ranging from indolent expansions of large granular lymphocytes, to aggressive diseases that are associated with a fulminant clinical course. Recent advances in genomic methodologies have massively increased the understanding of...
journal_title:Seminars in diagnostic pathology
pub_type: 杂志文章,评审
doi:10.1053/j.semdp.2019.12.001
更新日期:2020-01-01 00:00:00
abstract::Paraneoplastic syndromes (PNS) are rare clinical syndromes due to the systemic effects of tumours; they are unrelated to tumour size, invasiveness or metastases. Recent years have seen considerable advances leading to improved understanding of their pathophysiology and increased recognition of new PNS entities and PNS...
journal_title:Seminars in diagnostic pathology
pub_type: 杂志文章,评审
doi:10.1053/j.semdp.2019.01.002
更新日期:2019-07-01 00:00:00
abstract::A variety of soft tissue and visceral neoplasms have been associated with constitutional symptoms and signs including fever, fatigue, arthritis and laboratory abnormalities such as elevated erythrocyte sedimentation rate, leukocytosis with marked neutrophilia, anemia, thrombocytosis and others. This review addresses t...
journal_title:Seminars in diagnostic pathology
pub_type: 杂志文章,评审
doi:10.1053/j.semdp.2019.02.001
更新日期:2019-07-01 00:00:00
abstract::Lower respiratory infections remain one of the top global causes of death and the emergence of new diseases continues to be a concern. In the first two decades of the 21st century, we have born witness to the emergence of newly recognized coronaviruses that have rapidly spread around the globe, including severe acute ...
journal_title:Seminars in diagnostic pathology
pub_type: 杂志文章,评审
doi:10.1053/j.semdp.2019.04.006
更新日期:2019-05-01 00:00:00
abstract::Spindle cell/pleomorphic lipomas are benign lipomatous neoplasms that show loss of RB1 and classically harbor components of mature adipose tissue, bland spindled cells and ropy collagen. This review highlights the clinicopathologic features and morphologic spectrum of spindle cell/pleomorphic lipoma, discusses an upda...
journal_title:Seminars in diagnostic pathology
pub_type: 杂志文章,评审
doi:10.1053/j.semdp.2019.02.005
更新日期:2019-03-01 00:00:00
abstract::Developmental abnormalities and malformations of the breast are rare and encompass a variety of genetic, syndromic, acquired and sporadic conditions. Abnormalities in development may include irregularities in the nipple areolar complex and/or the underlying glandular tissue, resulting in under or overdevelopment of br...
journal_title:Seminars in diagnostic pathology
pub_type: 杂志文章,评审
doi:10.1053/j.semdp.2018.11.007
更新日期:2019-01-01 00:00:00
abstract::Non-neoplastic skin lesions comprise a sizable group of disorders with variable etiologies and clinical manifestations. They can be grouped into vesiculopustular dermatitides; spongiotic and psoriasiform diseases; lichenoid dermatitides; lymphoid infiltrates of the dermis; granulomatous processes; bullous disorders; v...
journal_title:Seminars in diagnostic pathology
pub_type: 杂志文章,评审
doi:10.1053/j.semdp.2018.10.006
更新日期:2018-11-01 00:00:00
abstract::The alimentary tract serves as host to a large number of diseases. In the non-neoplastic group of disorders, conventional histochemistry continues to play an important diagnostic role. It is particularly important in recognizing specific infectious diseases, such as Helicobacter gastritis, Whipple disease, intestinal ...
journal_title:Seminars in diagnostic pathology
pub_type: 杂志文章,评审
doi:10.1053/j.semdp.2018.10.002
更新日期:2018-11-01 00:00:00
abstract::Nonspecific interstitial pneumonia (NSIP) is a form of chronic interstitial pneumonia that should be separated from the other idiopathic interstitial pneumonias, including most importantly, usual interstitial pneumonia (UIP). Diagnosis is predicated on identification of characteristic findings in a surgical lung biops...
journal_title:Seminars in diagnostic pathology
pub_type: 杂志文章
doi:10.1053/j.semdp.2018.09.002
更新日期:2018-09-01 00:00:00
abstract::Bronchoalveolar lavage (BAL) is a noninvasive and well-tolerated procedure that is performed with a fiberoptic bronchoscope in the wedged position within a selected bronchopulmonary segment. After it was introduced to clinical practice, BAL rapidly gained acceptance in a large number of centers as a procedure that cou...
journal_title:Seminars in diagnostic pathology
pub_type: 杂志文章,评审
doi:10.1053/j.semdp.2018.08.003
更新日期:2018-09-01 00:00:00
abstract::The recognition and reporting of stromal and vascular lesions of the lymph node is rife with difficulties including relative rarity, a lack of familiarity with lesions and the challenges of using ancillary studies appropriately. In this manuscript, we highlight a range of benign stromal and vascular abnormalities that...
journal_title:Seminars in diagnostic pathology
pub_type: 杂志文章,评审
doi:10.1053/j.semdp.2017.11.004
更新日期:2018-01-01 00:00:00
abstract::This article describes the various non-neoplastic lymphadenopathies that occur in patients infected with the human immunodeficiency virus (HIV), before or during the stage of acquired immunodeficiency syndrome (AIDS). The stages that develop during the HIV infection include: primary infection (acute infection, spread ...
journal_title:Seminars in diagnostic pathology
pub_type: 杂志文章,评审
doi:10.1053/j.semdp.2017.12.001
更新日期:2018-01-01 00:00:00
abstract::Spindle cell lesions of the breast are among the less common entities encountered in breast pathology. They encompass a whole spectrum of benign reactive lesions to high grade malignant neoplasms. An accurate diagnosis is important to ensure that the patient receives the appropriate management. While this group of con...
journal_title:Seminars in diagnostic pathology
pub_type: 杂志文章,评审
doi:10.1053/j.semdp.2017.05.012
更新日期:2017-09-01 00:00:00
abstract::Antiretroviral therapy has significantly improved the quality and length of life for those patients able to access effective and sustained treatment. The resulting restoration of the immune response is associated with a change in the clinical presentation of opportunistic infections, and the histologic reaction to pat...
journal_title:Seminars in diagnostic pathology
pub_type: 杂志文章,评审
doi:10.1053/j.semdp.2017.04.010
更新日期:2017-07-01 00:00:00
abstract::Cutaneous CD30+ T-cell lymphoproliferative disorders (CD30+ T-LPD) represent a spectrum encompassing lymphomatoid papulosis (LyP), primary cutaneous anaplastic large-cell lymphoma (pcALCL) and borderline lesions. They share the expression of CD30 as a common phenotypic marker. They differ however in their clinical pre...
journal_title:Seminars in diagnostic pathology
pub_type: 杂志文章,评审
doi:10.1053/j.semdp.2016.11.005
更新日期:2017-01-01 00:00:00
abstract::A tribute to Pepper's lasting contributions to Hepatopathology. ...
journal_title:Seminars in diagnostic pathology
pub_type: 传,历史文章,杂志文章
doi:10.1053/j.semdp.2016.08.002
更新日期:2016-11-01 00:00:00
abstract::Since its foundation by remarkably talented and insightful individuals, prominently including Pepper Dehner, pediatric soft tissue tumor pathology has developed at an immense rate. The morphologic classification of tumoral entities has extensively been corroborated, but has also evolved with refinement or realignment ...
journal_title:Seminars in diagnostic pathology
pub_type: 杂志文章,评审
doi:10.1053/j.semdp.2016.08.008
更新日期:2016-11-01 00:00:00
abstract::Small cell carcinoma of the lung (SCLC) is a well characterized form of lung cancer that is frequently already metastatic at diagnosis. Thus, patients with SCLC are usually treated with chemotherapy, and therefore emphasis has been placed on distinguishing that tumor from squamous cell carcinomas, large cell carcinoma...
journal_title:Seminars in diagnostic pathology
pub_type: 杂志文章,评审
doi:10.1053/j.semdp.2015.11.001
更新日期:2015-11-01 00:00:00
abstract::Neuroendocrine neoplasms (NENs) can often present with metastatic disease before the primary tumor is discovered. Metastatic lesions are generally classified as well differentiated and poorly differentiated for prognostic and therapeutic purposes. In addition, for well-differentiated neuroendocrine tumors (WDNETs), pa...
journal_title:Seminars in diagnostic pathology
pub_type: 杂志文章,评审
doi:10.1053/j.semdp.2015.09.013
更新日期:2015-11-01 00:00:00
abstract::Non-lymphoid small round blue cell tumors of the head and neck are particularly difficult to diagnose when metastatic to a lymph node. The cytopathologist or surgical pathologist evaluating these lesions has to be aware of the various non-hematopoetic neoplasms that present in the head and neck area that can mimic non...
journal_title:Seminars in diagnostic pathology
pub_type: 杂志文章
doi:10.1053/j.semdp.2014.12.011
更新日期:2015-07-01 00:00:00
abstract::Mucinous cystic neoplasms (MCNs) of the pancreas are primary pancreatic cyst-forming neoplasms that can be a precursor to invasive adenocarcinoma of the pancreas. MCNs occur almost exclusively in the distal pancreas of middle-aged women. MCNs typically show a "cyst-in-cyst" pattern of growth and are well encapsulated ...
journal_title:Seminars in diagnostic pathology
pub_type: 杂志文章,评审
doi:10.1053/j.semdp.2014.08.007
更新日期:2014-11-01 00:00:00
abstract::The spectrum of testicular tumors and tumor-like lesions that affect young patients (defined for purposes of this article as less than 20 years old) differs significantly from that in an older age group. Although germ cell tumors remain the single largest category, they are a smaller proportion than in adults. Further...
journal_title:Seminars in diagnostic pathology
pub_type: 杂志文章
doi:10.1053/j.semdp.2014.07.003
更新日期:2014-09-01 00:00:00
abstract::Uncommon tumors in the uterus present diagnostic challenges. In some cases, the tumor subtype is usually seen outside the gynecologic tract and the possibility of a uterine primary is not considered. In other cases, histologic overlap with more common uterine tumors leads to potential misdiagnosis. Finally, metastatic...
journal_title:Seminars in diagnostic pathology
pub_type: 杂志文章,评审
doi:10.1053/j.semdp.2014.03.006
更新日期:2014-05-01 00:00:00
abstract::Ischemia is a common type of gastrointestinal injury that can be clinically misdiagnosed due to its often mild and transient clinical presentation as well as a tendency to masquerade as other disorders. A wide range of etiologies can contribute to the development of ischemia. These include hypovolemic states, systemic...
journal_title:Seminars in diagnostic pathology
pub_type: 杂志文章,评审
doi:10.1053/j.semdp.2014.02.001
更新日期:2014-03-01 00:00:00
abstract::Vascular tumors of the bone represent a variety of neoplasms, ranging from benign hemangiomas and epithelioid hemangiomas to intermediate grade hemangioendotheliomas to frankly malignant angiosarcomas. Over the years, there has been considerable debate concerning the aggressivity, nomenclature, and mere existence of v...
journal_title:Seminars in diagnostic pathology
pub_type: 杂志文章,评审
doi:10.1053/j.semdp.2014.01.003
更新日期:2014-01-01 00:00:00
abstract::Genetic and genomic analyses of melanocytic tumors have yielded new opportunities for improvements in diagnostic accuracy for the distinction of nevus from melanoma and better selection of patients affected by melanoma for targeted treatment. Since chromosomal copy number changes are commonly found in malignant melano...
journal_title:Seminars in diagnostic pathology
pub_type: 杂志文章,评审
doi:10.1053/j.semdp.2013.11.002
更新日期:2013-11-01 00:00:00
abstract::Recent developments in molecular genetics have expanded the spectrum of disorders associated with pheochromocytomas (PCCs) and extra-adrenal paragangliomas (PGLs) and have increased the roles of pathologists in helping to guide patient care. At least 30% of these tumors are now known to be hereditary, and germline mut...
journal_title:Seminars in diagnostic pathology
pub_type: 杂志文章,评审
doi:10.1053/j.semdp.2013.06.006
更新日期:2013-08-01 00:00:00
abstract::Recognition of the different types of multinucleated giant cells in neoplastic and pseudotumoral lesions of the skin may be helpful in the differential diagnosis of these tumors. In this review, we will analyze the different types of multinucleated giant cells that can be found in nonepithelial cutaneous tumors and, m...
journal_title:Seminars in diagnostic pathology
pub_type: 杂志文章,评审
doi:10.1053/j.semdp.2012.01.004
更新日期:2013-02-01 00:00:00
abstract::Retroperitoneal fibrosis is one of the prototypic manifestations of immunoglobulin G4 (IgG4)-related disease (IgG4-RD), but there is growing evidence that the aorta is also involved. These 2 conditions are closely linked, and based on the epicenter of the disease, the clinical manifestations can be classified as retro...
journal_title:Seminars in diagnostic pathology
pub_type: 杂志文章,评审
doi:10.1053/j.semdp.2012.07.003
更新日期:2012-11-01 00:00:00
abstract::Tumors of the ampulla-pancreatobiliary tract are encountered increasingly; however, their staging can be highly challenging due to lack of familiarity. In this review article, the various issues encountered in staging of these tumors at the pathologic level are evaluated and possible solutions for daily practice as we...
journal_title:Seminars in diagnostic pathology
pub_type: 杂志文章,评审
doi:10.1053/j.semdp.2012.08.010
更新日期:2012-08-01 00:00:00
abstract::Follicular lymphoma is one of the most frequent lymphomas in the western hemisphere. The diagnosis of this lymphoma is based primarily on morphology and immunohistochemistry. Although the basic diagnostic principles have been unchanged for decades, the concept of lymphoma pathogenesis and subtyping is still being deve...
journal_title:Seminars in diagnostic pathology
pub_type: 杂志文章,评审
doi:10.1053/j.semdp.2011.02.006
更新日期:2011-05-01 00:00:00
abstract::Primary malignant bone tumors are rare sarcomas with an estimated frequency of about 2900 new cases per year; they constitute less than 0.2% of all cancers diagnosed in the United States. The diagnosis and management of these neoplasms require a team approach, which includes orthopaedic surgeons, radiologists, patholo...
journal_title:Seminars in diagnostic pathology
pub_type: 杂志文章,评审
doi:10.1053/j.semdp.2011.02.002
更新日期:2011-02-01 00:00:00
abstract::Endometrial carcinomas are a heterogenous group of tumors that show variable histologies, molecular abnormalities and clinical outcomes. The idea of rigid distinctions between tumor types is appealing to pathologists, gynecologists, researchers and patients, but in a recent study where high grade endometrial carcinoma...
journal_title:Seminars in diagnostic pathology
pub_type: 杂志文章,评审
doi:10.1053/j.semdp.2010.09.003
更新日期:2010-11-01 00:00:00
abstract::Nontumor lesions of the spinal cord and spine include developmental disorders, cystic tumor-like lesions, vascular disorders, infective diseases, demyelinating diseases, degenerative diseases, metabolic and toxic disorders, and spinal cord injury. In addition, diseases of the spine and extradural spaces secondarily ca...
journal_title:Seminars in diagnostic pathology
pub_type: 杂志文章,评审
doi:10.1053/j.semdp.2010.05.004
更新日期:2010-08-01 00:00:00
abstract::Lobular carcinoma is a special type of breast cancer that shows distinct clinical presentation, morphologic and molecular features, and clinical behavior, and its incidence is rising in recent years. Infiltrating lobular carcinoma (ILC) and its precursor lesions may result in diagnostic difficulties, particularly in t...
journal_title:Seminars in diagnostic pathology
pub_type: 杂志文章,评审
doi:10.1053/j.semdp.2009.12.009
更新日期:2010-02-01 00:00:00
abstract::Since mid-1996 we have operated a diagnostic robotic telepathology (TP) system at the Iron Mountain, Michigan, Department of Veterans Affairs Medical Center (VAMC) from the Milwaukee, Wisconsin VAMC, located some 220 miles away. No on-site pathologist is present in Iron Mountain. Instead, an experienced, well-trained ...
journal_title:Seminars in diagnostic pathology
pub_type: 杂志文章
doi:10.1053/j.semdp.2009.09.007
更新日期:2009-11-01 00:00:00