abstract：BACKGROUND:Somatosensory deficits are prevalent after stroke, but effective interventions are limited. Brain stimulation of the contralesional primary somatosensory cortex (S1) is a promising adjunct to peripherally administered rehabilitation therapies. OBJECTIVE:To assess short-term effects of repetitive transcrania...

journal_title：Neurorehabilitation and neural repair

authors： Pundik S,Skelly M,McCabe J,Akbari H,Tatsuoka C,Plow EB

更新日期：2021-01-29 00:00:00

abstract：:A major problem in neurorehabilitation is the lack of objective outcomes to measure movement quality. Movement quality features, such as coordination and stability, are essential for everyday motor actions. These features allow reacting to continuously changing environment or to resist external perturbations. Neurolog...

journal_title：Neurorehabilitation and neural repair

authors： Solnik S,Furmanek MP,Piscitelli D

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Wrist-worn accelerometry provides objective monitoring of upper-extremity functional use, such as reaching tasks, but also detects nonfunctional movements, leading to ambiguity in monitoring results. OBJECTIVE:Compare machine learning algorithms with standard methods (counts ratio) to improve accuracy in de...

journal_title：Neurorehabilitation and neural repair

authors： Lum PS,Shu L,Bochniewicz EM,Tran T,Chang LC,Barth J,Dromerick AW

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Current available therapies for Parkinson disease (PD) have strong limitations, and patients usually present with refractory symptoms despite all efforts. Deep brain stimulation (DBS), which has been used in PD patients for decades (since 1987), has best indications for symptoms like tremor, motor fluctuatio...

journal_title：Neurorehabilitation and neural repair

authors： Garcia BB,Junior ER,Araújo MFP,Simplício H

更新日期：2020-11-01 00:00:00

abstract：:Background. Concussions affect nearly 3 million people a year and are the leading cause of traumatic brain injury-related emergency department visits among youth. Evidence shows neuromotor regions are sensitive to concussive events and that motor symptoms may be the earliest clinical manifestations of neurodegenerativ...

journal_title：Neurorehabilitation and neural repair

authors： Cantarero G,Choynowski J,St Pierre M,Anaya M,Statton M,Stokes W,Capaldi V,Chib V,Celnik P

更新日期：2020-09-01 00:00:00

abstract：:Background. Stroke is one of the most common causes of physical disability worldwide. The majority of survivors experience impairment of movement, often with lasting deficits affecting hand dexterity. To date, conventional rehabilitation primarily focuses on training compensatory maneuvers emphasizing goal completion ...

journal_title：Neurorehabilitation and neural repair

authors： Mawase F,Cherry-Allen K,Xu J,Anaya M,Uehara S,Celnik P

更新日期：2020-08-01 00:00:00

abstract：:Background. Mesenchymal stem cell (MSC)-derived exosomes play a critical role in regenerative medicine. Objective. To determine the dose- and time-dependent efficacy of exosomes for treatment of traumatic brain injury (TBI). Methods. Male rats were subjected to a unilateral moderate cortical contusion. In the dose-res...

journal_title：Neurorehabilitation and neural repair

authors： Zhang Y,Zhang Y,Chopp M,Zhang ZG,Mahmood A,Xiong Y

更新日期：2020-07-01 00:00:00

abstract：:Background. Although dopaminergic medication improves dual task walking in people with Parkinson disease (PD), the underlying neural mechanisms are not yet fully understood. As prefrontal cognitive resources are involved in dual task walking, evaluation of the prefrontal cortex (PFC) is required. Objective. To investi...

journal_title：Neurorehabilitation and neural repair

authors： Orcioli-Silva D,Vitório R,Nóbrega-Sousa P,da Conceição NR,Beretta VS,Lirani-Silva E,Gobbi LTB

更新日期：2020-07-01 00:00:00

abstract：:Background. Reorganization in motor areas have been suggested after motor imagery training (MIT). However, motor imagery involves a large-scale brain network, in which many regions, andnot only the motor areas, potentially constitute the neural substrate for MIT. Objective. This study aimed to identify the targets for...

journal_title：Neurorehabilitation and neural repair

authors： Wang X,Wang H,Xiong X,Sun C,Zhu B,Xu Y,Fan M,Tong S,Sun L,Guo X

更新日期：2020-04-01 00:00:00

abstract：:Background. High-intensity repetitive training is challenging to provide poststroke. Robotic approaches can facilitate such training by unweighting the limb and/or by improving trajectory control, but the extent to which these types of assistance are necessary is not known. Objective. The purpose of this study was to ...

journal_title：Neurorehabilitation and neural repair

authors： Raghavan P,Bilaloglu S,Ali SZ,Jin X,Aluru V,Buckley MC,Tang A,Yousefi A,Stone J,Agrawal SK,Lu Y

更新日期：2020-02-01 00:00:00

abstract：:Background. Severe poststroke arm impairment is associated with greater activation of the nonlesioned hemisphere during movement of the affected arm. The circumstances under which this activation may be adaptive or maladaptive remain unclear. Objective. To identify the functional relevance of key lesioned and nonlesio...

journal_title：Neurorehabilitation and neural repair

authors： Harrington RM,Chan E,Rounds AK,Wutzke CJ,Dromerick AW,Turkeltaub PE,Harris-Love ML

更新日期：2020-01-01 00:00:00

abstract：:Despite negative association in cognition and memory, mice harboring Val66Met BDNF SNP (BDNFM/M) exhibit enhanced motor recovery accompanied by elevated excitatory synaptic markers VGLUT1 and VGLUT2 in striatum contralateral to unilateral ischemic stroke. The cortico-striatal pathway is a critical gateway for plastici...

journal_title：Neurorehabilitation and neural repair

authors： Qin L,Actor-Engel HS,Woo MS,Shakil F,Chen YW,Cho S,Aoki C

更新日期：2019-12-01 00:00:00

abstract：:Objective. Stroke recovery is a multidimensional process influenced by biological and psychosocial factors. To understand the latter, we mapped the social networks of stroke patients, analyzing their changes and effects on physical function at 3 and 6 months after stroke. Methods. We used a quantitative social network...

journal_title：Neurorehabilitation and neural repair

authors： Dhand A,Lang CE,Luke DA,Kim A,Li K,McCafferty L,Mu Y,Rosner B,Feske SK,Lee JM

更新日期：2019-11-01 00:00:00

abstract：:Background. Understanding the factors that influence language recovery in aphasia is important for improving prognosis and treatment. Chronic comprehension impairments in Wernicke's aphasia (WA) are associated with impairments in auditory and phonological processing, compounded by semantic and executive difficulties. ...

journal_title：Neurorehabilitation and neural repair

authors： Robson H,Griffiths TD,Grube M,Woollams AM

更新日期：2019-10-01 00:00:00

abstract：:One in 2 Canadians is expected to acquire cancer in their lifetime. Many cancers, including breast, ovarian, and lung cancer, are treated using taxane chemotherapy with curative intent. A major adverse effect with the use of taxane chemotherapeutic agents is taxane-induced peripheral neuropathy (TIPN). Both positive (...

journal_title：Neurorehabilitation and neural repair

authors： Andersen Hammond E,Pitz M,Shay B

更新日期：2019-10-01 00:00:00

abstract：:Background. Motoneuron loss is a severe medical problem that can result in loss of motor control and eventually death. We have previously demonstrated that partial motoneuron loss can result in dendritic atrophy and functional deficits in nearby surviving motoneurons, and that treatment with androgens can be neuroprot...

journal_title：Neurorehabilitation and neural repair

authors： Chew C,Sengelaub DR

更新日期：2019-08-01 00:00:00

abstract：:Background. After stroke, recovery of movement in proximal and distal upper extremity (UE) muscles appears to follow different time courses, suggesting differences in their neural substrates. Objective. We sought to determine if presence or absence of motor evoked potentials (MEPs) differentially influences recovery o...

journal_title：Neurorehabilitation and neural repair

authors： Schambra HM,Xu J,Branscheidt M,Lindquist M,Uddin J,Steiner L,Hertler B,Kim N,Berard J,Harran MD,Cortes JC,Kitago T,Luft A,Krakauer JW,Celnik PA

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Recovery of the sit-to-stand (StS) movement early after stroke could be improved by targeting physical therapy at the underlying movement deficits in those people likely to respond. AIM:To compare the movement characteristics of successful and failed StS movements in people early after stroke and identify w...

journal_title：Neurorehabilitation and neural repair

authors： Kerr A,Clark A,Pomeroy VM

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Physical rehabilitation programs can lead to improvements in mobility in people with multiple sclerosis (PwMS). OBJECTIVE:To identify which rehabilitation program elements are employed in real life and how they might affect mobility improvement in PwMS. METHODS:Participants were divided into improved and n...

journal_title：Neurorehabilitation and neural repair

authors： Kalron A,Feys P,Dalgas U,Smedal T,Freeman J,Romberg A,Conyers H,Elorriaga I,Gebara B,Merilainen J,Heric-Mansrud A,Jensen E,Jones K,Knuts K,Maertens de Noordhout B,Martic A,Normann B,O Eijnde B,Rasova K,Santoyo Medin

更新日期：2019-04-01 00:00:00

abstract：:Approximately one-third of stroke patients suffer visual field impairment as a result of their strokes. However, studies using the visual pathway as a paradigm for studying poststroke recovery are limited. In this article, we propose that the visual pathway has many features that make it an excellent model system for ...

journal_title：Neurorehabilitation and neural repair

authors： Busza A,Schneider CL,Williams ZR,Mahon BZ,Sahin B

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:High-intensity, variable stepping training can improve walking speed in individuals poststroke, although neuromuscular strategies used to achieve faster speeds are unclear. We evaluated changes in joint kinetics and neuromuscular coordination following such training; movement strategies consistent with intac...

journal_title：Neurorehabilitation and neural repair

authors： Ardestani MM,Kinnaird CR,Henderson CE,Hornby TG

更新日期：2019-01-01 00:00:00

abstract：:Implementation is the use of strategies to adopt and integrate evidence-based health interventions and to change practice patterns. In their article, "Implementation-the missing link in the research translation pipeline," Lynch et al1 report that only a small fraction of published stroke rehabilitation research in lea...

journal_title：Neurorehabilitation and neural repair

authors： Morrato EH

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Gait impairments after stroke arise from dysfunction of one or several features of the walking pattern. Traditional rehabilitation practice focuses on improving one component at a time, which may leave certain features unaddressed or prolong rehabilitation time. Recent work shows that neurologically intact a...

journal_title：Neurorehabilitation and neural repair

authors： Cherry-Allen KM,Statton MA,Celnik PA,Bastian AJ

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Peripheral axon regeneration is improved when the nerve lesion under consideration has recently been preceded by another nerve injury. This is known as the conditioning lesion effect (CLE). While the CLE is one of the most robust and well characterized means to enhance motor axon regeneration in experimental...

journal_title：Neurorehabilitation and neural repair

authors： Franz CK,Puritz A,Jordan LA,Chow J,Ortega JA,Kiskinis E,Heckman CJ

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Contradictory results have been reported for transcranial direct current stimulation (tDCS) as treatment for tinnitus. The recently developed high-definition tDCS (HD tDCS) uses smaller electrodes to limit the excitation to the desired brain areas. OBJECTIVE:The current study consisted of a retrospective pa...

journal_title：Neurorehabilitation and neural repair

authors： Jacquemin L,Shekhawat GS,Van de Heyning P,Mertens G,Fransen E,Van Rompaey V,Topsakal V,Moyaert J,Beyers J,Gilles A

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Damage to the callosal motor fibers (CMFs) may affect motor recovery in patients with stroke. However, whether the severity of CMF impairment varies with lesion locations remains unclear. OBJECTIVE:To investigate (1) whether CMF impairment occurs after stroke and whether the impairment varies with lesion lo...

journal_title：Neurorehabilitation and neural repair

authors： Koh CL,Tang PF,Chen HI,Hsu YC,Hsieh CL,Tseng WI

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Individuals with unilateral vestibular hypofunction (UVH) alter their movement and reduce mobility to try to stabilize their gaze and avoid symptoms of dizziness and vertigo. OBJECTIVE:To determine if individuals with UVH 6 weeks after surgery demonstrate altered head and trunk kinematics during community a...

journal_title：Neurorehabilitation and neural repair

authors： Paul SS,Dibble LE,Walther RG,Shelton C,Gurgel RK,Lester ME

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Motor training alone or combined with transcranial direct current stimulation (tDCS) positioned over the motor cortex (M1) improves motor function in chronic stroke. Currently, understanding of how tDCS influences the process of motor skill learning after stroke is lacking. OBJECTIVE:To assess the effects o...

journal_title：Neurorehabilitation and neural repair

authors： Hamoudi M,Schambra HM,Fritsch B,Schoechlin-Marx A,Weiller C,Cohen LG,Reis J

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVE:To systematically review the literature with meta-analysis to determine whether persistence of sensorimotor or physiological impairment exists between 4 weeks to 6 months post mild traumatic brain injury (mTBI), and assign level of evidence to findings. METHOD:The databases PubMed, pscyINFO, SPORTdiscus, Med...

journal_title：Neurorehabilitation and neural repair

authors： Galea OA,Cottrell MA,Treleaven JM,O'Leary SP

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:There is a need to identify reliable biomarkers of spinal cord injury recovery for clinical practice and clinical trials. OBJECTIVE:Our objective was to correlate serum albumin levels with spinal cord injury neurological outcomes. METHODS:We performed a secondary analysis of patients with traumatic spinal ...

journal_title：Neurorehabilitation and neural repair

authors： Tong B,Jutzeler CR,Cragg JJ,Grassner L,Schwab JM,Casha S,Geisler F,Kramer JLK

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Many physical interventions can improve locomotor function in individuals with motor incomplete spinal cord injury (iSCI), although the training parameters that maximize recovery are not clear. Previous studies in individuals with other neurologic injuries suggest the intensity of locomotor training (LT) may...

journal_title：Neurorehabilitation and neural repair

authors： Brazg G,Fahey M,Holleran CL,Connolly M,Woodward J,Hennessy PW,Schmit BD,Hornby TG

更新日期：2017-10-01 00:00:00

abstract：:The first Stroke Recovery and Rehabilitation Roundtable established a game changing set of new standards for stroke recovery research. Common language and definitions were required to develop an agreed framework spanning the four working groups: translation of basic science, biomarkers of stroke recovery, measurement ...

journal_title：Neurorehabilitation and neural repair

authors： Bernhardt J,Hayward KS,Kwakkel G,Ward NS,Wolf SL,Borschmann K,Krakauer JW,Boyd LA,Carmichael ST,Corbett D,Cramer SC

更新日期：2017-09-01 00:00:00

abstract：:Stroke recovery research involves distinct biological and clinical targets compared to the study of acute stroke. Guidelines are proposed for the pre-clinical modeling of stroke recovery and for the alignment of pre-clinical studies to clinical trials in stroke recovery. ...

journal_title：Neurorehabilitation and neural repair

authors： Corbett D,Carmichael ST,Murphy TH,Jones TA,Schwab ME,Jolkkonen J,Clarkson AN,Dancause N,Weiloch T,Johansen-Berg H,Nilsson M,McCullough LD,Joy MT

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Recovery from stroke is often said to have "plateaued" after 6 to 12 months. Yet training can still improve performance even in the chronic phase. Here we investigate the biomechanics of accuracy improvements during a reaching task and test whether they are affected by the speed at which movements are practi...

journal_title：Neurorehabilitation and neural repair

authors： Hammerbeck U,Yousif N,Hoad D,Greenwood R,Diedrichsen J,Rothwell JC

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The course of central and peripheral motor recovery after cervical spinal cord injury (SCI) may be investigated by electrophysiological measures. The goal of this study was to compare the 2 over the first year after injury in relation to motor gains. METHODS:Compound motor action potentials (C...

journal_title：Neurorehabilitation and neural repair

authors： Petersen JA,Spiess M,Curt A,Weidner N,Rupp R,Abel R,EM-SCI Study Group.,Schubert M

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:The use of exercise in amyotrophic lateral sclerosis (ALS) is controversial. Although moderate exercise appears to be beneficial for limb muscles in ALS, the effects of exercise on bulbar muscles such as the tongue have not been studied. OBJECTIVE:To determine the effects of tongue force training on bulbar ...

journal_title：Neurorehabilitation and neural repair

authors： Ma D,Shuler JM,Kumar A,Stanford QR,Tungtur S,Nishimune H,Stanford JA

更新日期：2017-02-01 00:00:00

abstract：:The remarkable scientific and technological advances in the field of cell research have not been translated into viable restorative therapies for brain disorders. In this article, we examine the best available evidence for the clinical efficacy of reconstructive intracerebral transplantation in people with Parkinson's...

journal_title：Neurorehabilitation and neural repair

authors： Polgar S,Karimi L,Buultjens M,Morris ME

更新日期：2016-10-01 00:00:00

abstract：OBJECTIVE:To investigate the individual occurrence of walking-related motor fatigue in persons with multiple sclerosis (PwMS), according to disability level and disease phenotype.Study design This was a cross-sectional, multinational study.Participants They were 208 PwMS from 11 centers with Expanded Disability Status ...

journal_title：Neurorehabilitation and neural repair

authors： Leone C,Severijns D,Doležalová V,Baert I,Dalgas U,Romberg A,Bethoux F,Gebara B,Santoyo Medina C,Maamâgi H,Rasova K,Maertens de Noordhout B,Knuts K,Skjerbaek A,Jensen E,Wagner JM,Feys P

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Our ability to sense movement is essential for motor control; however, the impact of kinesthesia deficits on functional recovery is not well monitored in the spinal cord injury (SCI) population. One problem is the lack of accurate and reliable tools to measure kinesthesia. OBJECTIVE:The purpose of this stud...

journal_title：Neurorehabilitation and neural repair

authors： Chisholm AE,Domingo A,Jeyasurya J,Lam T

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:To investigate the effectiveness of upper limb rehabilitation, sound measures of upper limb function, capacity, and performance are paramount. OBJECTIVES:This systematic review investigates reliability and responsiveness of upper limb measurement tools used in pediatric neurorehabilitation. METHODS:A 2-tie...

journal_title：Neurorehabilitation and neural repair

authors： Gerber CN,Labruyère R,van Hedel HJ

更新日期：2016-01-01 00:00:00