A Critical Evaluation of the Methodological Obstacles to Translating Cell-Based Research Into an Effective Treatment for People With Parkinson's Disease.

abstract：:Background and Purpose. Patients with chronic stroke may benefit from continuing rehabilitation training after hospital discharge. This study examined whether caregiver-mediated, home-based intervention (CHI) could improve physical functioning and social participation in these patients. Methods. A single-blind, random...

journal_title：Neurorehabilitation and neural repair

authors： Wang TC,Tsai AC,Wang JY,Lin YT,Lin KL,Chen JJ,Lin BY,Lin TC

更新日期：2015-01-01 00:00:00

abstract：:Background. Motoneuron loss is a severe medical problem that can result in loss of motor control and eventually death. We have previously demonstrated that partial motoneuron loss can result in dendritic atrophy and functional deficits in nearby surviving motoneurons, and that treatment with androgens can be neuroprot...

journal_title：Neurorehabilitation and neural repair

authors： Chew C,Sengelaub DR

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:. Mental practice through motor imagery improves subsequent motor performance and thus mental training is considered to be a potential tool in neuromotor rehabilitation. OBJECTIVE:. The authors investigated whether a circadian fluctuation of the motor imagery process occurs, which could be relevant in sched...

journal_title：Neurorehabilitation and neural repair

authors： Gueugneau N,Mauvieux B,Papaxanthis C

更新日期：2009-03-01 00:00:00

abstract：:Stroke recovery research involves distinct biological and clinical targets compared to the study of acute stroke. Guidelines are proposed for the pre-clinical modeling of stroke recovery and for the alignment of pre-clinical studies to clinical trials in stroke recovery. ...

journal_title：Neurorehabilitation and neural repair

authors： Corbett D,Carmichael ST,Murphy TH,Jones TA,Schwab ME,Jolkkonen J,Clarkson AN,Dancause N,Weiloch T,Johansen-Berg H,Nilsson M,McCullough LD,Joy MT

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Stroke patients with a low memory self-efficacy (MSE) report more memory complaints than patients with a high MSE. OBJECTIVE:The aim of this study was to examine the effect of a memory-training program on MSE in the chronic phase after stroke and to identify which patients benefit most from the MSE training...

journal_title：Neurorehabilitation and neural repair

authors： Aben L,Heijenbrok-Kal MH,van Loon EM,Groet E,Ponds RW,Busschbach JJ,Ribbers GM

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Several pilot studies have evoked interest in robot-assisted therapy (RAT) in children with cerebral palsy (CP). OBJECTIVE:To assess the effectiveness of RAT in children with CP through a single-blind randomized controlled trial. PATIENTS AND METHODS:Sixteen children with CP were randomized into 2 groups. ...

journal_title：Neurorehabilitation and neural repair

authors： Gilliaux M,Renders A,Dispa D,Holvoet D,Sapin J,Dehez B,Detrembleur C,Lejeune TM,Stoquart G

更新日期：2015-02-01 00:00:00

abstract：STATEMENT OF PROBLEM:To develop and evaluate a self-administered health-related quality of life (HRQOL) measure for peripheral neuropathy. METHODS:A field test measure of 162 items was developed that included the RAND-36 Health Survey as a generic core and a neuropathy-targeted supplement whose content was driven by r...

journal_title：Neurorehabilitation and neural repair

authors： Vickrey BG,Hays RD,Beckstrand M

更新日期：2000-01-01 00:00:00

abstract：:Background. High-intensity repetitive training is challenging to provide poststroke. Robotic approaches can facilitate such training by unweighting the limb and/or by improving trajectory control, but the extent to which these types of assistance are necessary is not known. Objective. The purpose of this study was to ...

journal_title：Neurorehabilitation and neural repair

authors： Raghavan P,Bilaloglu S,Ali SZ,Jin X,Aluru V,Buckley MC,Tang A,Yousefi A,Stone J,Agrawal SK,Lu Y

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Long-term use of a foot-drop stimulator applying functional electrical stimulation (FES) to the common peroneal nerve improves walking performance even when the stimulator is off. This "therapeutic" effect might result from neuroplastic changes. OBJECTIVE:To determine the effect of long-term use of a foot-d...

journal_title：Neurorehabilitation and neural repair

authors： Everaert DG,Thompson AK,Chong SL,Stein RB

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVE:To examine whether cerebral activity during passive movements decreases with time after stroke, and if reduced activity in the representation for the upper extremity can be reversed with training. METHODS:Brain activity was measured by functional magnetic resonance imaging (fMRI) during passive wrist flexion...

journal_title：Neurorehabilitation and neural repair

authors： Lindberg PG,Schmitz C,Engardt M,Forssberg H,Borg J

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:Alterations in the function of spinal neuronal circuits underlying locomotion after a spinal cord injury (SCI) are associated with changes in the behavior of spinal reflexes (SRs) in both rats and humans. In healthy subjects, the SR consists of a dominant early reflex component, whereas in chronic, severely ...

journal_title：Neurorehabilitation and neural repair

authors： Hubli M,Dietz V,Bolliger M

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Confidence about balance may be an important factor affecting self-efficacy for daily activities after stroke. OBJECTIVE:The authors investigated whether confidence changes and the parameters that may predict changes in self-perceived balance within the first year of community reintegration. METHODS:In thi...

journal_title：Neurorehabilitation and neural repair

authors： Yiu J,Miller WC,Eng JJ,Liu Y

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Contradictory results have been reported for transcranial direct current stimulation (tDCS) as treatment for tinnitus. The recently developed high-definition tDCS (HD tDCS) uses smaller electrodes to limit the excitation to the desired brain areas. OBJECTIVE:The current study consisted of a retrospective pa...

journal_title：Neurorehabilitation and neural repair

authors： Jacquemin L,Shekhawat GS,Van de Heyning P,Mertens G,Fransen E,Van Rompaey V,Topsakal V,Moyaert J,Beyers J,Gilles A

更新日期：2018-08-01 00:00:00

abstract：:Background. After stroke, recovery of movement in proximal and distal upper extremity (UE) muscles appears to follow different time courses, suggesting differences in their neural substrates. Objective. We sought to determine if presence or absence of motor evoked potentials (MEPs) differentially influences recovery o...

journal_title：Neurorehabilitation and neural repair

authors： Schambra HM,Xu J,Branscheidt M,Lindquist M,Uddin J,Steiner L,Hertler B,Kim N,Berard J,Harran MD,Cortes JC,Kitago T,Luft A,Krakauer JW,Celnik PA

更新日期：2019-07-01 00:00:00

abstract：PURPOSE:Sarcopenia and increased fat infiltration in muscle may play a role in the functional impairment and high risk for diabetes in stroke. Our purpose was to compare muscle volume and muscle attenuation across 6 muscles of the paretic and nonparetic thigh and examine the relationships between intramuscular fat and ...

journal_title：Neurorehabilitation and neural repair

authors： Ryan AS,Buscemi A,Forrester L,Hafer-Macko CE,Ivey FM

更新日期：2011-11-01 00:00:00

abstract：:The purpose of this study was to estimate the overall cost of managing focal spasticity after stroke (CVA) and traumatic brain injury (TBI) and the cost impact of individual treatments. Sixty physicians described management strategies over six treatment visits for four focal spasticity case studies (one upper and one ...

journal_title：Neurorehabilitation and neural repair

authors： Radensky PW,Archer JW,Dournaux SF,O'Brien CF

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Damage to the callosal motor fibers (CMFs) may affect motor recovery in patients with stroke. However, whether the severity of CMF impairment varies with lesion locations remains unclear. OBJECTIVE:To investigate (1) whether CMF impairment occurs after stroke and whether the impairment varies with lesion lo...

journal_title：Neurorehabilitation and neural repair

authors： Koh CL,Tang PF,Chen HI,Hsu YC,Hsieh CL,Tseng WI

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Stroke survivors can exhibit abnormally elevated oxygen consumption during walking. Therapeutic interventions can improve gait deficits and oxygen consumption. A practical measure of oxygen cost is not available. This study tested the usefulness of an indirect index of oxygen cost, the Physiological Cost Ind...

journal_title：Neurorehabilitation and neural repair

authors： Fredrickson E,Ruff RL,Daly JJ

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:Upper limb function plays a significant role in enhancing independence for individuals with tetraplegia. However, there is limited knowledge about the specific input of sensorimotor deficits on upper limb function. Thus the theoretical framework designed to develop the Graded Redefined Assessment of Strength...

journal_title：Neurorehabilitation and neural repair

authors： Kalsi-Ryan S,Beaton D,Curt A,Duff S,Jiang D,Popovic MR,Rudhe C,Fehlings MG,Verrier MC

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Peripheral axon regeneration is improved when the nerve lesion under consideration has recently been preceded by another nerve injury. This is known as the conditioning lesion effect (CLE). While the CLE is one of the most robust and well characterized means to enhance motor axon regeneration in experimental...

journal_title：Neurorehabilitation and neural repair

authors： Franz CK,Puritz A,Jordan LA,Chow J,Ortega JA,Kiskinis E,Heckman CJ

更新日期：2018-08-01 00:00:00

abstract：:Background The reliable stratification of homogeneous subgroups and the prediction of future clinical outcomes within heterogeneous neurological disorders is a particularly challenging task. Nonetheless, it is essential for the implementation of targeted care and effective therapeutic interventions. Objective This stu...

journal_title：Neurorehabilitation and neural repair

authors： Tanadini LG,Steeves JD,Hothorn T,Abel R,Maier D,Schubert M,Weidner N,Rupp R,Curt A

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Objective measures of functional walking remain scarce for individuals with incomplete spinal cord injury (ISCI). Hence, the authors developed the Spinal Cord Injury Functional Ambulation Profile (SCI-FAP), which encompasses the timed performance of 7 tasks, such as walking and negotiating obstacles, doors, ...

journal_title：Neurorehabilitation and neural repair

authors： Musselman K,Brunton K,Lam T,Yang J

更新日期：2011-03-01 00:00:00

abstract：:Background. Concussions affect nearly 3 million people a year and are the leading cause of traumatic brain injury-related emergency department visits among youth. Evidence shows neuromotor regions are sensitive to concussive events and that motor symptoms may be the earliest clinical manifestations of neurodegenerativ...

journal_title：Neurorehabilitation and neural repair

authors： Cantarero G,Choynowski J,St Pierre M,Anaya M,Statton M,Stokes W,Capaldi V,Chib V,Celnik P

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Ambulating on stairs is an important aspect of daily activities for many individuals with incomplete spinal cord injury (SCI), and little is known about the effect of training for this specific task. OBJECTIVE:The goal of this study was to determine whether staircase ascent training enhances motor recovery ...

journal_title：Neurorehabilitation and neural repair

authors： Singh A,Murray M,Houle JD

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Recovery of the sit-to-stand (StS) movement early after stroke could be improved by targeting physical therapy at the underlying movement deficits in those people likely to respond. AIM:To compare the movement characteristics of successful and failed StS movements in people early after stroke and identify w...

journal_title：Neurorehabilitation and neural repair

authors： Kerr A,Clark A,Pomeroy VM

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:This study investigated the relative effects of distributed constraint-induced therapy (CIT) and bilateral arm training (BAT) on motor performance, daily function, functional use of the affected arm, and quality of life in patients with hemiparetic stroke. METHODS:A total of 60 patients were r...

journal_title：Neurorehabilitation and neural repair

authors： Lin KC,Chang YF,Wu CY,Chen YA

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:In hemiplegic gait, step length typically differs in magnitude between paretic and nonparetic sides. However, the direction of step-length asymmetry varies across stroke patients. OBJECTIVE:The study sought to understand directional variations in step-length asymmetry in terms of asymmetries in forward foot...

journal_title：Neurorehabilitation and neural repair

authors： Roerdink M,Beek PJ

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Step length asymmetry (SLA) is a common hallmark of gait poststroke. Though conventionally viewed as a spatial deficit, SLA can result from differences in where the feet are placed relative to the body (step position strategy), the timing between foot strikes (step time strategy), or the velocity of the body...

journal_title：Neurorehabilitation and neural repair

authors： Finley JM,Long A,Bastian AJ,Torres-Oviedo G

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Community-dwelling, chronic stroke survivors are at risk of falling during turning and are more likely to sustain a hip fracture when they fall. OBJECTIVE:This study quantifies kinematic differences between stroke survivors (mean +/- SD: 38.3 +/- 31.3 months post-stroke, 59.9 +/- 10.1 years of age), with (n...

journal_title：Neurorehabilitation and neural repair

authors： Hollands KL,Hollands MA,Zietz D,Wing AM,Wright C,van Vliet P

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Many physical interventions can improve locomotor function in individuals with motor incomplete spinal cord injury (iSCI), although the training parameters that maximize recovery are not clear. Previous studies in individuals with other neurologic injuries suggest the intensity of locomotor training (LT) may...

journal_title：Neurorehabilitation and neural repair

authors： Brazg G,Fahey M,Holleran CL,Connolly M,Woodward J,Hennessy PW,Schmit BD,Hornby TG

更新日期：2017-10-01 00:00:00