Botulinum Toxin Conditioning Enhances Motor Axon Regeneration in Mouse and Human Preclinical Models.

abstract：OBJECTIVE:There are indications that perilesional and remote peripheral motor axons may degenerate after spinal cord injury (SCI). The authors investigated the magnitude and dependence on severity of SCI of this degeneration as well as whether motor axons so affected can recover. METHODS:The function of the peripheral...

journal_title：Neurorehabilitation and neural repair

authors： Van De Meent H,Hosman AJ,Hendriks J,Zwarts M,EM-SCI Study Group.,Schubert M

更新日期：2010-09-01 00:00:00

abstract：:Background. Reorganization in motor areas have been suggested after motor imagery training (MIT). However, motor imagery involves a large-scale brain network, in which many regions, andnot only the motor areas, potentially constitute the neural substrate for MIT. Objective. This study aimed to identify the targets for...

journal_title：Neurorehabilitation and neural repair

authors： Wang X,Wang H,Xiong X,Sun C,Zhu B,Xu Y,Fan M,Tong S,Sun L,Guo X

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Retraining walking following spinal cord injury using visually guided tasks may be especially efficacious because it engages the motor cortex, whose input may facilitate improvements in functional walking. OBJECTIVES:To contrast 2 methods of retraining, one emphasizing precise, visually guided walking over ...

journal_title：Neurorehabilitation and neural repair

authors： Yang JF,Musselman KE,Livingstone D,Brunton K,Hendricks G,Hill D,Gorassini M

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Although functional imaging and neurophysiological approaches reveal alterations in motor and premotor areas after stroke, insights into neurobiological events underlying these alterations are limited in human studies. OBJECTIVE:We tested whether cerebral metabolites related to neuronal and glial compartmen...

journal_title：Neurorehabilitation and neural repair

authors： Craciunas SC,Brooks WM,Nudo RJ,Popescu EA,Choi IY,Lee P,Yeh HW,Savage CR,Cirstea CM

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Robot-assisted therapy (RT) is a current promising intervention in stroke rehabilitation, but more research is warranted for examining its efficacy and the dose-benefit relation. The authors investigated the effects of higher intensity versus lower intensity RT on movements of forearm pronatio...

journal_title：Neurorehabilitation and neural repair

authors： Hsieh YW,Wu CY,Liao WW,Lin KC,Wu KY,Lee CY

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:and purpose. Mental practice (MP), which involves cognitive rehearsal of physical movements, is a noninvasive, inexpensive method of enabling repetitive, task-specific practice (RTP). Recent, randomized controlled data suggest that MP, when combined with an RTP therapy program, increases affected arm use and...

journal_title：Neurorehabilitation and neural repair

authors： Page SJ,Szaflarski JP,Eliassen JC,Pan H,Cramer SC

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Individuals with stroke often sustain bone loss on the hemiparetic side and are prone to fragility fractures. Exercise training may be a viable way to promote bone mineral density (BMD) and geometry in this population. OBJECTIVE:This was a pilot study to evaluate the effects of a 6-month treadmill exercise ...

journal_title：Neurorehabilitation and neural repair

authors： Pang MY,Lau RW

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Confidence about balance may be an important factor affecting self-efficacy for daily activities after stroke. OBJECTIVE:The authors investigated whether confidence changes and the parameters that may predict changes in self-perceived balance within the first year of community reintegration. METHODS:In thi...

journal_title：Neurorehabilitation and neural repair

authors： Yiu J,Miller WC,Eng JJ,Liu Y

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Cortical networks underlying motor imagery are functionally close to motor performance networks and can be activated by patients with severe motor disabilities. OBJECTIVE:The aim of the study was to examine the longitudinal effect of progressive motoneuron degeneration on cortical representation of motor im...

journal_title：Neurorehabilitation and neural repair

authors： Lulé D,Diekmann V,Kassubek J,Kurt A,Birbaumer N,Ludolph AC,Kraft E

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Gait impairments after stroke arise from dysfunction of one or several features of the walking pattern. Traditional rehabilitation practice focuses on improving one component at a time, which may leave certain features unaddressed or prolong rehabilitation time. Recent work shows that neurologically intact a...

journal_title：Neurorehabilitation and neural repair

authors： Cherry-Allen KM,Statton MA,Celnik PA,Bastian AJ

更新日期：2018-09-01 00:00:00

abstract：OBJECTIVE:This study investigated the blood lactate accumulation during two wheelchair-racing protocols. During exercise, energy is required, which causes metabolism to increase and blood lactate to accumulate. Proper training can reduce the amount of blood lactate accumulation and increase tolerance to blood lactate a...

journal_title：Neurorehabilitation and neural repair

authors： Cooper RA,Baldini FD,Boninger ML,Cooper R

更新日期：2001-01-01 00:00:00

abstract：:A major problem in neurorehabilitation is the lack of objective outcomes to measure movement quality. Movement quality features, such as coordination and stability, are essential for everyday motor actions. These features allow reacting to continuously changing environment or to resist external perturbations. Neurolog...

journal_title：Neurorehabilitation and neural repair

authors： Solnik S,Furmanek MP,Piscitelli D

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Dysphagia diagnosis is limited by our inability to evaluate the underlying neuromuscular pathology of swallowing. A novel approach using pharyngeal surface electromyography (PsEMG) has been reported in the literature. OBJECTIVE:Three exploratory projects were undertaken to provide data toward the validation...

journal_title：Neurorehabilitation and neural repair

authors： Doeltgen SH,Hofmayer A,Gumbley F,Witte U,Moran C,Carroll G,Huckabee ML

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVE:To systematically review the literature with meta-analysis to determine whether persistence of sensorimotor or physiological impairment exists between 4 weeks to 6 months post mild traumatic brain injury (mTBI), and assign level of evidence to findings. METHOD:The databases PubMed, pscyINFO, SPORTdiscus, Med...

journal_title：Neurorehabilitation and neural repair

authors： Galea OA,Cottrell MA,Treleaven JM,O'Leary SP

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:A recent review showed that no existing instrument measured the entire spectrum of health-related quality of life (HRQOL) in stroke patients. However, the HRQOL in stroke patients (HRQOLISP) questionnaire is valid and exceptionally comprehensive. Founded on a holistic model of human life, it comprises both p...

journal_title：Neurorehabilitation and neural repair

authors： Ojo Owolabi M

更新日期：2010-11-01 00:00:00

abstract：:Previous literature has suggested that reflex sympathetic dystrophy, also known as complex regional pain syndrome (CRPS) type 1, is a relatively common finding after a stroke. However, much of this data was obtained before patients routinely received early intensive inpatient rehabilitation. The purpose of this study ...

journal_title：Neurorehabilitation and neural repair

authors： Petchkrua W,Weiss DJ,Patel RR

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Bell's palsy (BP) is the most frequent form of peripheral palsy of the facial nerve. Prognosis for recovery is good for most patients; in the remaining cases, different grades of residual impairment persist. Physical therapy, in association with drug administration, aims to improve outcomes. OBJECTIVE:To as...

journal_title：Neurorehabilitation and neural repair

authors： Nicastri M,Mancini P,De Seta D,Bertoli G,Prosperini L,Toni D,Inghilleri M,Filipo R

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVE:Recent reports have indicated that bone marrow stromal cells (BMSCs) have the potential to improve neurological function when transplanted into models of central nervous system (CNS) disorders, including traumatic spinal cord injury. In this study, the authors aimed to clarify the underlying mechanism through...

journal_title：Neurorehabilitation and neural repair

authors： Shichinohe H,Kuroda S,Tsuji S,Yamaguchi S,Yano S,Lee JB,Kobayashi H,Kikuchi S,Hida K,Iwasaki Y

更新日期：2008-09-01 00:00:00

abstract：:The purpose of this study was to estimate the overall cost of managing focal spasticity after stroke (CVA) and traumatic brain injury (TBI) and the cost impact of individual treatments. Sixty physicians described management strategies over six treatment visits for four focal spasticity case studies (one upper and one ...

journal_title：Neurorehabilitation and neural repair

authors： Radensky PW,Archer JW,Dournaux SF,O'Brien CF

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:High-intensity, variable stepping training can improve walking speed in individuals poststroke, although neuromuscular strategies used to achieve faster speeds are unclear. We evaluated changes in joint kinetics and neuromuscular coordination following such training; movement strategies consistent with intac...

journal_title：Neurorehabilitation and neural repair

authors： Ardestani MM,Kinnaird CR,Henderson CE,Hornby TG

更新日期：2019-01-01 00:00:00

abstract：:The first Stroke Recovery and Rehabilitation Roundtable established a game changing set of new standards for stroke recovery research. Common language and definitions were required to develop an agreed framework spanning the four working groups: translation of basic science, biomarkers of stroke recovery, measurement ...

journal_title：Neurorehabilitation and neural repair

authors： Bernhardt J,Hayward KS,Kwakkel G,Ward NS,Wolf SL,Borschmann K,Krakauer JW,Boyd LA,Carmichael ST,Corbett D,Cramer SC

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Functional magnetic resonance imaging (fMRI) of motor impairment after stroke strongly depends on patient effort and capacity to make a movement. Hence fMRI has had limited use in clinical management. Alternatively, resting-state fMRI (ie, with no task) can elucidate the brain's functional connections by det...

journal_title：Neurorehabilitation and neural repair

authors： Golestani AM,Tymchuk S,Demchuk A,Goodyear BG,VISION-2 Study Group.

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Hemiparetic gait following stroke requires substantial energy consumption, which would promote deconditioning and disability. Optimal modalities for decreasing this energy cost remain challenging. Excessive energy consumption, however, seems to be mainly due to extra positive muscle work to substantially lif...

journal_title：Neurorehabilitation and neural repair

authors： Massaad F,Lejeune TM,Detrembleur C

更新日期：2010-05-01 00:00:00

abstract：:Background The reliable stratification of homogeneous subgroups and the prediction of future clinical outcomes within heterogeneous neurological disorders is a particularly challenging task. Nonetheless, it is essential for the implementation of targeted care and effective therapeutic interventions. Objective This stu...

journal_title：Neurorehabilitation and neural repair

authors： Tanadini LG,Steeves JD,Hothorn T,Abel R,Maier D,Schubert M,Weidner N,Rupp R,Curt A

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Objective measures of functional walking remain scarce for individuals with incomplete spinal cord injury (ISCI). Hence, the authors developed the Spinal Cord Injury Functional Ambulation Profile (SCI-FAP), which encompasses the timed performance of 7 tasks, such as walking and negotiating obstacles, doors, ...

journal_title：Neurorehabilitation and neural repair

authors： Musselman K,Brunton K,Lam T,Yang J

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:. Mental practice through motor imagery improves subsequent motor performance and thus mental training is considered to be a potential tool in neuromotor rehabilitation. OBJECTIVE:. The authors investigated whether a circadian fluctuation of the motor imagery process occurs, which could be relevant in sched...

journal_title：Neurorehabilitation and neural repair

authors： Gueugneau N,Mauvieux B,Papaxanthis C

更新日期：2009-03-01 00:00:00

abstract：:This article summarizes the proceedings of an NIH workshop on timing, intensity, and duration of rehabilitation for acute stroke and hip fracture. Participants concentrated on methodological issues facing investigators and suggested priorities for future research in this area. ...

journal_title：Neurorehabilitation and neural repair

authors： Weinrich M,Good DC,Reding M,Roth EJ,Cifu DX,Silver KH,Craik RL,Magaziner J,Terrin M,Schwartz M,Gerber L

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:Upper limb function plays a significant role in enhancing independence for individuals with tetraplegia. However, there is limited knowledge about the specific input of sensorimotor deficits on upper limb function. Thus the theoretical framework designed to develop the Graded Redefined Assessment of Strength...

journal_title：Neurorehabilitation and neural repair

authors： Kalsi-Ryan S,Beaton D,Curt A,Duff S,Jiang D,Popovic MR,Rudhe C,Fehlings MG,Verrier MC

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Environmental enrichment (EE) is a complex living milieu that has been shown to enhance functional recovery versus standard (STD) housing after experimental traumatic brain injury (TBI) and therefore may be considered a rodent correlate of rehabilitation. However, the typical EE paradigm consists of continuo...

journal_title：Neurorehabilitation and neural repair

authors： de Witt BW,Ehrenberg KM,McAloon RL,Panos AH,Shaw KE,Raghavan PV,Skidmore ER,Kline AE

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Some noninvasive brain-computer interface (BCI) systems are currently available for locked-in syndrome (LIS) but none have incorporated a statistical language model during text generation. OBJECTIVE:To begin to address the communication needs of individuals with LIS using a noninvasive BCI that involves rap...

journal_title：Neurorehabilitation and neural repair

authors： Oken BS,Orhan U,Roark B,Erdogmus D,Fowler A,Mooney A,Peters B,Miller M,Fried-Oken MB

更新日期：2014-05-01 00:00:00