Using Vision to Study Poststroke Recovery and Test Hypotheses About Neurorehabilitation.

Abstract:

:Approximately one-third of stroke patients suffer visual field impairment as a result of their strokes. However, studies using the visual pathway as a paradigm for studying poststroke recovery are limited. In this article, we propose that the visual pathway has many features that make it an excellent model system for studying poststroke neuroplasticity and assessing the efficacy of therapeutic interventions. First, the functional anatomy of the visual pathway is well characterized, which makes it well suited for functional neuroimaging studies of poststroke recovery. Second, there are multiple highly standardized and clinically available diagnostic tools and outcome measures that can be used to assess visual function in stroke patients. Finally, as a sensory modality, the assessment of vision is arguably less likely to be affected by confounding factors such as functional compensation and patient motivation. Given these advantages, and the general similarities between poststroke visual field recovery and recovery in other functional domains, future neurorehabilitation studies should consider using the visual pathway to better understand the physiology of neurorecovery and test potential therapeutics.

authors

Busza A,Schneider CL,Williams ZR,Mahon BZ,Sahin B

doi

10.1177/1545968319827569

subject

Has Abstract

pub_date

2019-02-01 00:00:00

pages

87-95

issue

2

eissn

1545-9683

issn

1552-6844

journal_volume

33

pub_type

杂志文章
  • Factors contributing to motor impairment and recovery after stroke.

    abstract::The goal of the present study was to examine factors affecting motor impairment and recovery in a primate model of cortical infarction. Microelectrode stimulation techniques were used to delineate the hand representation in the primary motor cortex (M1). Microinfarcts affecting approximately 30% of the hand representa...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/154596830001400406

    authors: Heddings AA,Friel KM,Plautz EJ,Barbay S,Nudo RJ

    更新日期:2000-01-01 00:00:00

  • Neuroprotective Effects of Exercise on the Morphology of Somatic Motoneurons Following the Death of Neighboring Motoneurons.

    abstract::Background. Motoneuron loss is a severe medical problem that can result in loss of motor control and eventually death. We have previously demonstrated that partial motoneuron loss can result in dendritic atrophy and functional deficits in nearby surviving motoneurons, and that treatment with androgens can be neuroprot...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968319860485

    authors: Chew C,Sengelaub DR

    更新日期:2019-08-01 00:00:00

  • Assessing Proprioception: A Systematic Review of Possibilities.

    abstract::Proprioception is a vital aspect of motor control and when degraded or lost can have a profound impact on function in diverse clinical populations. This systematic review aimed to identify clinically related tools to measure proprioceptive acuity, to classify the construct(s) underpinning the tools, and to report on t...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章,评审

    doi:10.1177/1545968315573055

    authors: Hillier S,Immink M,Thewlis D

    更新日期:2015-11-01 00:00:00

  • Searching for the "Active Ingredients" in Physical Rehabilitation Programs Across Europe, Necessary to Improve Mobility in People With Multiple Sclerosis: A Multicenter Study.

    abstract:BACKGROUND:Physical rehabilitation programs can lead to improvements in mobility in people with multiple sclerosis (PwMS). OBJECTIVE:To identify which rehabilitation program elements are employed in real life and how they might affect mobility improvement in PwMS. METHODS:Participants were divided into improved and n...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章,多中心研究

    doi:10.1177/1545968319834893

    authors: Kalron A,Feys P,Dalgas U,Smedal T,Freeman J,Romberg A,Conyers H,Elorriaga I,Gebara B,Merilainen J,Heric-Mansrud A,Jensen E,Jones K,Knuts K,Maertens de Noordhout B,Martic A,Normann B,O Eijnde B,Rasova K,Santoyo Medin

    更新日期:2019-04-01 00:00:00

  • Admission ambulation velocity predicts length of stay and discharge disposition following stroke in an acute rehabilitation hospital.

    abstract:BACKGROUND AND PURPOSE:Poststroke functional outcome and discharge disposition are influenced by age, lesion location and size, severity of neurological insult, prior functional ability, and social support. The effect of admission ambulation velocity on length of stay and discharge disposition has not been previously r...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968304272762

    authors: Rabadi MH,Blau A

    更新日期:2005-03-01 00:00:00

  • Auditory, Phonological, and Semantic Factors in the Recovery From Wernicke's Aphasia Poststroke: Predictive Value and Implications for Rehabilitation.

    abstract::Background. Understanding the factors that influence language recovery in aphasia is important for improving prognosis and treatment. Chronic comprehension impairments in Wernicke's aphasia (WA) are associated with impairments in auditory and phonological processing, compounded by semantic and executive difficulties. ...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968319868709

    authors: Robson H,Griffiths TD,Grube M,Woollams AM

    更新日期:2019-10-01 00:00:00

  • Cortical and spinal excitability changes after robotic gait training in healthy participants.

    abstract:BACKGROUND:Recent studies have proposed a role for robotic gait training in participants with acquired brain injury, but the effects on the excitability of cortical and spinal neurons even in healthy participants are uncertain. OBJECTIVE:To investigate changes in corticospinal excitability in healthy participants afte...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968308317973

    authors: Blicher JU,Nielsen JF

    更新日期:2009-02-01 00:00:00

  • Caregiver-mediated intervention can improve physical functional recovery of patients with chronic stroke: a randomized controlled trial.

    abstract::Background and Purpose. Patients with chronic stroke may benefit from continuing rehabilitation training after hospital discharge. This study examined whether caregiver-mediated, home-based intervention (CHI) could improve physical functioning and social participation in these patients. Methods. A single-blind, random...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1177/1545968314532030

    authors: Wang TC,Tsai AC,Wang JY,Lin YT,Lin KL,Chen JJ,Lin BY,Lin TC

    更新日期:2015-01-01 00:00:00

  • Defining the role of sensation, strength, and prehension for upper limb function in cervical spinal cord injury.

    abstract:BACKGROUND:Upper limb function plays a significant role in enhancing independence for individuals with tetraplegia. However, there is limited knowledge about the specific input of sensorimotor deficits on upper limb function. Thus the theoretical framework designed to develop the Graded Redefined Assessment of Strength...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968313490998

    authors: Kalsi-Ryan S,Beaton D,Curt A,Duff S,Jiang D,Popovic MR,Rudhe C,Fehlings MG,Verrier MC

    更新日期:2014-01-01 00:00:00

  • Quantification of Lower Extremity Kinesthesia Deficits Using a Robotic Exoskeleton in People With a Spinal Cord Injury.

    abstract:BACKGROUND:Our ability to sense movement is essential for motor control; however, the impact of kinesthesia deficits on functional recovery is not well monitored in the spinal cord injury (SCI) population. One problem is the lack of accurate and reliable tools to measure kinesthesia. OBJECTIVE:The purpose of this stud...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968315591703

    authors: Chisholm AE,Domingo A,Jeyasurya J,Lam T

    更新日期:2016-03-01 00:00:00

  • Repetitive mass practice or focused precise practice for retraining walking after incomplete spinal cord injury? A pilot randomized clinical trial.

    abstract:BACKGROUND:Retraining walking following spinal cord injury using visually guided tasks may be especially efficacious because it engages the motor cortex, whose input may facilitate improvements in functional walking. OBJECTIVES:To contrast 2 methods of retraining, one emphasizing precise, visually guided walking over ...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章,随机对照试验

    doi:10.1177/1545968313508473

    authors: Yang JF,Musselman KE,Livingstone D,Brunton K,Hendricks G,Hill D,Gorassini M

    更新日期:2014-05-01 00:00:00

  • Assessing the motor status score: a scale for the evaluation of upper limb motor outcomes in patients after stroke.

    abstract::The Motor Status Scale (MSS) measures shoulder, elbow (maximum score = 40), wrist, hand, and finger movements (maximum score = 42), and expands the measurement of upper extremity impairment and disability provided by the Fugl-Meyer (FM) score. This work examines the interrater reliability and criterion validity of the...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 临床试验,杂志文章

    doi:10.1177/154596830201600306

    authors: Ferraro M,Demaio JH,Krol J,Trudell C,Rannekleiv K,Edelstein L,Christos P,Aisen M,England J,Fasoli S,Krebs HI,Hogan N,Volpe BT

    更新日期:2002-09-01 00:00:00

  • A Critical Evaluation of the Methodological Obstacles to Translating Cell-Based Research Into an Effective Treatment for People With Parkinson's Disease.

    abstract::The remarkable scientific and technological advances in the field of cell research have not been translated into viable restorative therapies for brain disorders. In this article, we examine the best available evidence for the clinical efficacy of reconstructive intracerebral transplantation in people with Parkinson's...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968316635277

    authors: Polgar S,Karimi L,Buultjens M,Morris ME

    更新日期:2016-10-01 00:00:00

  • Upper limb robot-assisted therapy in cerebral palsy: a single-blind randomized controlled trial.

    abstract:BACKGROUND:Several pilot studies have evoked interest in robot-assisted therapy (RAT) in children with cerebral palsy (CP). OBJECTIVE:To assess the effectiveness of RAT in children with CP through a single-blind randomized controlled trial. PATIENTS AND METHODS:Sixteen children with CP were randomized into 2 groups. ...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章,随机对照试验

    doi:10.1177/1545968314541172

    authors: Gilliaux M,Renders A,Dispa D,Holvoet D,Sapin J,Dehez B,Detrembleur C,Lejeune TM,Stoquart G

    更新日期:2015-02-01 00:00:00

  • Movement Quality: A Novel Biomarker Based on Principles of Neuroscience.

    abstract::A major problem in neurorehabilitation is the lack of objective outcomes to measure movement quality. Movement quality features, such as coordination and stability, are essential for everyday motor actions. These features allow reacting to continuously changing environment or to resist external perturbations. Neurolog...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968320969936

    authors: Solnik S,Furmanek MP,Piscitelli D

    更新日期:2020-12-01 00:00:00

  • Effect of a foot-drop stimulator and ankle-foot orthosis on walking performance after stroke: a multicenter randomized controlled trial.

    abstract:BACKGROUND:Studies have demonstrated the efficacy of functional electrical stimulation in the management of foot drop after stroke. OBJECTIVE:To compare changes in walking performance with the WalkAide (WA) foot-drop stimulator and a conventional ankle-foot orthosis (AFO). METHODS:Individuals with stroke within the p...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1177/1545968313481278

    authors: Everaert DG,Stein RB,Abrams GM,Dromerick AW,Francisco GE,Hafner BJ,Huskey TN,Munin MC,Nolan KJ,Kufta CV

    更新日期:2013-09-01 00:00:00

  • Circadian modulation of mentally simulated motor actions: implications for the potential use of motor imagery in rehabilitation.

    abstract:BACKGROUND:. Mental practice through motor imagery improves subsequent motor performance and thus mental training is considered to be a potential tool in neuromotor rehabilitation. OBJECTIVE:. The authors investigated whether a circadian fluctuation of the motor imagery process occurs, which could be relevant in sched...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968308321775

    authors: Gueugneau N,Mauvieux B,Papaxanthis C

    更新日期:2009-03-01 00:00:00

  • Interference between cognition, double-limb support, and swing during gait in community-dwelling individuals poststroke.

    abstract:BACKGROUND:Dual tasking can interfere with activity after stroke. OBJECTIVE:The authors examined the interactions between 3 different cognitive tasks and the swing and double-limb support (DLS) components of the gait cycle in community-dwelling individuals poststroke. METHODS:Acquisition of cognitive and gait data we...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968309357926

    authors: Plummer-D'Amato P,Altmann LJ,Behrman AL,Marsiske M

    更新日期:2010-07-01 00:00:00

  • Reduced Purposeful Head Movements During Community Ambulation Following Unilateral Vestibular Loss.

    abstract:BACKGROUND:Individuals with unilateral vestibular hypofunction (UVH) alter their movement and reduce mobility to try to stabilize their gaze and avoid symptoms of dizziness and vertigo. OBJECTIVE:To determine if individuals with UVH 6 weeks after surgery demonstrate altered head and trunk kinematics during community a...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968318770271

    authors: Paul SS,Dibble LE,Walther RG,Shelton C,Gurgel RK,Lester ME

    更新日期:2018-04-01 00:00:00

  • Neuropathic Pain in Taxane-Induced Peripheral Neuropathy: Evidence for Exercise in Treatment.

    abstract::One in 2 Canadians is expected to acquire cancer in their lifetime. Many cancers, including breast, ovarian, and lung cancer, are treated using taxane chemotherapy with curative intent. A major adverse effect with the use of taxane chemotherapeutic agents is taxane-induced peripheral neuropathy (TIPN). Both positive (...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章,评审

    doi:10.1177/1545968319860486

    authors: Andersen Hammond E,Pitz M,Shay B

    更新日期:2019-10-01 00:00:00

  • Minimal detectable change and clinically important difference of the Stroke Impact Scale in stroke patients.

    abstract:OBJECTIVES:The purpose of this study was to establish the minimal detectable change (MDC) and clinically important differences (CIDs) of the physical domains of the Stroke Impact Scale (SIS) and to assess the proportions of patients' change scores exceeding the MDC and CIDs after stroke rehabilitation. METHODS:Seventy...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章,随机对照试验

    doi:10.1177/1545968309356295

    authors: Lin KC,Fu T,Wu CY,Wang YH,Liu JS,Hsieh CJ,Lin SF

    更新日期:2010-06-01 00:00:00

  • Assisted movement with enhanced sensation (AMES): coupling motor and sensory to remediate motor deficits in chronic stroke patients.

    abstract:BACKGROUND:Conventional methods of rehabilitation in patients with chronic, severe motor impairments after stroke usually do not lessen paresis. OBJECTIVE:A novel therapeutic approach (assisted movement with enhanced sensation [AMES]) was employed in a medical device phase I clinical trial to reduce paresis and spasti...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968308317437

    authors: Cordo P,Lutsep H,Cordo L,Wright WG,Cacciatore T,Skoss R

    更新日期:2009-01-01 00:00:00

  • Reliability and Responsiveness of Upper Limb Motor Assessments for Children With Central Neuromotor Disorders: A Systematic Review.

    abstract:BACKGROUND:To investigate the effectiveness of upper limb rehabilitation, sound measures of upper limb function, capacity, and performance are paramount. OBJECTIVES:This systematic review investigates reliability and responsiveness of upper limb measurement tools used in pediatric neurorehabilitation. METHODS:A 2-tie...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章,评审

    doi:10.1177/1545968315583723

    authors: Gerber CN,Labruyère R,van Hedel HJ

    更新日期:2016-01-01 00:00:00

  • A training paradigm to enhance motor recovery in contused rats: effects of staircase training.

    abstract:BACKGROUND:Ambulating on stairs is an important aspect of daily activities for many individuals with incomplete spinal cord injury (SCI), and little is known about the effect of training for this specific task. OBJECTIVE:The goal of this study was to determine whether staircase ascent training enhances motor recovery ...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968310378510

    authors: Singh A,Murray M,Houle JD

    更新日期:2011-01-01 00:00:00

  • Effects of Training Intensity on Locomotor Performance in Individuals With Chronic Spinal Cord Injury: A Randomized Crossover Study.

    abstract:BACKGROUND:Many physical interventions can improve locomotor function in individuals with motor incomplete spinal cord injury (iSCI), although the training parameters that maximize recovery are not clear. Previous studies in individuals with other neurologic injuries suggest the intensity of locomotor training (LT) may...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章,随机对照试验

    doi:10.1177/1545968317731538

    authors: Brazg G,Fahey M,Holleran CL,Connolly M,Woodward J,Hennessy PW,Schmit BD,Hornby TG

    更新日期:2017-10-01 00:00:00

  • Motor cortical disinhibition during early and late recovery after stroke.

    abstract:BACKGROUND:Functional neuroimaging studies show adaptive changes in areas adjacent and distant from the stroke. This longitudinal study assessed whether changes in cortical excitability in affected and unaffected motor areas after acute stroke correlates with functional and motor recovery. METHODS:We studied 13 patien...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968307313505

    authors: Manganotti P,Acler M,Zanette GP,Smania N,Fiaschi A

    更新日期:2008-07-01 00:00:00

  • Fatigue perceived by multiple sclerosis patients is associated with muscle fatigue.

    abstract:BACKGROUND:Fatigue is a debilitating symptom in multiple sclerosis (MS). Previous studies showed no association between fatigue as perceived by the patient and physiological measures of fatigability. OBJECTIVE:The authors investigated associations between perceived fatigue and measures of fatigability after correction...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968311416991

    authors: Steens A,de Vries A,Hemmen J,Heersema T,Heerings M,Maurits N,Zijdewind I

    更新日期:2012-01-01 00:00:00

  • Effects of treatment intensity in upper limb robot-assisted therapy for chronic stroke: a pilot randomized controlled trial.

    abstract:BACKGROUND AND OBJECTIVES:Robot-assisted therapy (RT) is a current promising intervention in stroke rehabilitation, but more research is warranted for examining its efficacy and the dose-benefit relation. The authors investigated the effects of higher intensity versus lower intensity RT on movements of forearm pronatio...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章,随机对照试验

    doi:10.1177/1545968310394871

    authors: Hsieh YW,Wu CY,Liao WW,Lin KC,Wu KY,Lee CY

    更新日期:2011-07-01 00:00:00

  • How long is the recovery of global aphasia? Twenty-five years of follow-up in a patient with left hemisphere stroke.

    abstract:BACKGROUND:Current knowledge regarding the time course of aphasia recovery is based on observations limited to the first years after stroke. OBJECTIVE:The authors studied long-term outcome (25 years) of language in a patient with global aphasia. METHODS:A 37-year-old man with global aphasia from a large ischemic lesi...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968310368962

    authors: Smania N,Gandolfi M,Aglioti SM,Girardi P,Fiaschi A,Girardi F

    更新日期:2010-11-01 00:00:00

  • The effects of treadmill exercise training on hip bone density and tibial bone geometry in stroke survivors: a pilot study.

    abstract:BACKGROUND:Individuals with stroke often sustain bone loss on the hemiparetic side and are prone to fragility fractures. Exercise training may be a viable way to promote bone mineral density (BMD) and geometry in this population. OBJECTIVE:This was a pilot study to evaluate the effects of a 6-month treadmill exercise ...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968309353326

    authors: Pang MY,Lau RW

    更新日期:2010-05-01 00:00:00