abstract：:The nomogram reported by Gandaglia et al (The key combined value of multiparametric magnetic resonance imaging, and magnetic resonance imaging-targeted and concomitant systematic biopsies for the prediction of adverse pathological features in prostate cancer patients undergoing radical prostatectomy. Eur Urol 2020;77:...

journal_title：European urology

authors： Diamand R,Ploussard G,Roumiguié M,Oderda M,Benamran D,Fiard G,Quackels T,Assenmacher G,Simone G,Van Damme J,Malavaud B,Iselin C,Descotes JL,Roche JB,Peltier A,Roumeguère T,Albisinni S

更新日期：2021-02-01 00:00:00

abstract：CONTEXT:In response to growing concerns over rising costs and major variation in quality, improving value for patients has been proposed as a fundamentally new strategy for how healthcare should be delivered, measured, and remunerated. OBJECTIVE:To systematically review the literature regarding the implementation and ...

journal_title：European urology

authors： Reitblat C,Bain PA,Porter ME,Bernstein DN,Feeley TW,Graefen M,Iyer S,Resnick MJ,Stimson CJ,Trinh QD,Gershman B

更新日期：2021-01-04 00:00:00

abstract：CONTEXT:The European Association of Urology (EAU) Guidelines Panel on Upper Urinary Tract Urothelial Carcinoma (UTUC) has prepared updated guidelines to aid clinicians in the current evidence-based management of UTUC and to incorporate recommendations into clinical practice. OBJECTIVE:To provide an overview of the EAU...

journal_title：European urology

authors： Rouprêt M,Babjuk M,Burger M,Capoun O,Cohen D,Compérat EM,Cowan NC,Dominguez-Escrig JL,Gontero P,Hugh Mostafid A,Palou J,Peyronnet B,Seisen T,Soukup V,Sylvester RJ,Rhijn BWGV,Zigeuner R,Shariat SF

更新日期：2021-01-01 00:00:00

abstract：:The burden of prostate cancer is increasing. Therefore, we need to implement a contemporary, organized, risk-stratified program for early detection to reduce both the harm from the disease and potential overdiagnosis and overtreatment, while avoiding underdiagnosis to considerably improve the harm-to-benefit ratio. ...

journal_title：European urology

authors： Van Poppel H,Hogenhout R,Albers P,van den Bergh RCN,Barentsz JO,Roobol MJ

更新日期：2020-12-28 00:00:00

abstract：BACKGROUND:Radical perineal prostatectomy (RPP) has been revived with the advent of single-port (SP) robotic surgery. However, its interest and precise role need to be evaluated and better defined. OBJECTIVE:To describe in detail the technique of SP-RPP and compare initial perioperative outcomes with those of multipor...

journal_title：European urology

authors： Lenfant L,Garisto J,Sawczyn G,Wilson CA,Aminsharifi A,Kim S,Schwen Z,Bertolo R,Kaouk J

更新日期：2020-12-20 00:00:00

abstract：BACKGROUND:Activating mutations in AKT1 and PIK3CA are undercharacterised in metastatic castration-resistant prostate cancer (mCRPC), but are linked to activation of phosphatidylinositol 3-kinase (PI3K) signalling and sensitivity to pathway inhibitors in other cancers. OBJECTIVE:To determine the prevalence, genomic co...

journal_title：European urology

authors： Herberts C,Murtha AJ,Fu S,Wang G,Schönlau E,Xue H,Lin D,Gleave A,Yip S,Angeles A,Hotte S,Tran B,North S,Taavitsainen S,Beja K,Vandekerkhove G,Ritch E,Warner E,Saad F,Iqbal N,Nykter M,Gleave ME,Wang Y,Annala

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Despite recent technical innovations in the treatment of benign prostatic hyperplasia (BPH), retrograde ejaculation is still one of the most frequent adverse effects, with a major impact on patients' quality of life. OBJECTIVE:To evaluate the efficacy of our technique of urethral-sparing robotic-assisted si...

journal_title：European urology

authors： Porpiglia F,Checcucci E,Amparore D,Niculescu G,Volpi G,Piramide F,De Cillis S,Manfredi M,Autorino R,Fiori C

更新日期：2020-10-05 00:00:00

abstract：BACKGROUND:Robot-assisted thrombectomy (RAT) for inferior vena cava (IVC) thrombus (RAT-IVCT) is being increasingly reported. However, the techniques and indications for robot-assisted cavectomy (RAC) for IVC thrombus are not well described. OBJECTIVE:To develop a decision-making program and analyze multi-institutiona...

journal_title：European urology

authors： Shi T,Huang Q,Liu K,Du S,Fan Y,Yang L,Peng C,Shen D,Wang Z,Gao Y,Gu L,Niu S,Ai Q,Li H,Liu F,Li Q,Wang H,Guo A,Fu B,Yang X,Zhang X,Wang D,Wang D,Guo H,Li H,Olivero A,Fam XI,Ma X,Wang B,Zhang X

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Over the years, several techniques for performing robot-assisted prostatectomy have been implemented in an effort to achieve optimal oncological and functional outcomes. OBJECTIVE:To provide an evidence-based description and video-based illustration of currently available dissection techniques for robotic p...

journal_title：European urology

authors： Martini A,Falagario UG,Villers A,Dell'Oglio P,Mazzone E,Autorino R,Moschovas MC,Buscarini M,Bravi CA,Briganti A,Sawczyn G,Kaouk J,Menon M,Secco S,Bocciardi AM,Wang G,Zhou X,Porpiglia F,Mottrie A,Patel V,Tewari AK

更新日期：2020-10-01 00:00:00

abstract：:Preclinical models and early clinical data suggest an interplay between the gut microbiome and response to immunotherapy in solid tumors including metastatic renal cell carcinoma (mRCC). We sought to characterize the stool microbiome of mRCC patients receiving a checkpoint inhibitor (CPI) and to assess treatment-relat...

journal_title：European urology

authors： Salgia NJ,Bergerot PG,Maia MC,Dizman N,Hsu J,Gillece JD,Folkerts M,Reining L,Trent J,Highlander SK,Pal SK

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:The feasibility and efficacy of robot-assisted radical prostatectomy (RARP) in locally advanced prostate cancer (PCa) patients with iT3 lesion at magnetic resonance imaging (MRI) are currently not explored. OBJECTIVE:To describe our revised RARP technique (ie, superextended RARP [SE-RARP]) for PCa patients ...

journal_title：European urology

authors： Mazzone E,Dell'Oglio P,Rosiello G,Puliatti S,Brook N,Turri F,Larcher A,Beato S,Andras I,Wisz P,Pandey A,De Groote R,Schatteman P,De Naeyer G,D'Hondt F,Mottrie A

更新日期：2020-09-14 00:00:00

abstract：BACKGROUND:Recently, robot-assisted kidney transplantation (RAKT) was recently introduced as renal replacement mini-invasive surgery. OBJECTIVE:To report surgical technique, including tips and tricks, and the learning curve for RAKT. DESIGN, SETTING, AND PARTICIPANTS:All consecutive RAKTs performed in the five highes...

journal_title：European urology

authors： Gallioli A,Territo A,Boissier R,Campi R,Vignolini G,Musquera M,Alcaraz A,Decaestecker K,Tugcu V,Vanacore D,Serni S,Breda A

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Muscle-invasive bladder cancer (MIBC) is the second most common genitourinary malignancy, and is associated with high morbidity and mortality. Recently, molecular subtypes of MIBC have been identified, which have important clinical implications. OBJECTIVE:In the current study, we tried to predict the molecu...

journal_title：European urology

authors： Woerl AC,Eckstein M,Geiger J,Wagner DC,Daher T,Stenzel P,Fernandez A,Hartmann A,Wand M,Roth W,Foersch S

更新日期：2020-08-01 00:00:00

abstract：:Preliminary data suggest that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is associated with higher mortality among cancer patients, particularly in those on systemic therapy. It is unclear whether this applies to patients receiving immune checkpoint inhibitors (ICIs). In this case series, 7...

journal_title：European urology

authors： Szabados B,Abu-Ghanem Y,Grant M,Choy J,Bex A,Powles T

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Cyclic high-dose testosterone injections, also known as bipolar androgen therapy (BAT), is a novel treatment strategy for patients with metastatic castration-resistant prostate cancer (mCRPC). BAT has shown clinical activity in prior studies enrolling men with mCRPC and may potentially restore sensitivity to...

journal_title：European urology

authors： Markowski MC,Wang H,Sullivan R,Rifkind I,Sinibaldi V,Schweizer MT,Teply BA,Ngomba N,Fu W,Carducci MA,Paller CJ,Marshall CH,Eisenberger MA,Luo J,Antonarakis ES,Denmeade SR

更新日期：2020-07-02 00:00:00

abstract：BACKGROUND:Level III-IV robot-assisted inferior vena cava (IVC) thrombectomy (RA-IVCT) has been reported in limited series. OBJECTIVE:To report our initial series of level III-IV RA-IVCT with step-by-step procedures and 1-yr outcomes. DESIGN, SETTING, AND PARTICIPANTS:From November 2014 to January 2018, 13 patients w...

journal_title：European urology

authors： Wang B,Huang Q,Liu K,Fan Y,Peng C,Gu L,Shi T,Zhang P,Chen W,Du S,Niu S,Liu R,Zhao G,Li Q,Xiao C,Wang R,Li S,Wang M,Liu F,Wang H,Li H,Ma X,Zhang X

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Renal cell carcinomas (RCCs) are a heterogeneous group of neoplasms. Recent sequencing studies revealed various molecular features associated with histologic RCC subtypes, including chromophobe renal cell carcinoma (ChRCC). OBJECTIVE:To characterize the gene expression and biomarker signatures associated wi...

journal_title：European urology

authors： Skala SL,Wang X,Zhang Y,Mannan R,Wang L,Narayanan SP,Vats P,Su F,Chen J,Cao X,Siddiqui J,Argani P,Cieślik MP,Giordano TJ,Chinnaiyan AM,Dhanasekaran SM,Mehra R

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Magnetic resonance imaging (MRI) has been proposed as a staging tool for bladder cancer (BC), but its use has been limited by its high costs and limited availability. Microultrasound (mUS) is a novel technology capable of providing high-resolution images of the prostate. OBJECTIVE:To test the feasibility of...

journal_title：European urology

authors： Saita A,Lughezzani G,Buffi NM,Hurle R,Nava L,Colombo P,Diana P,Fasulo V,Paciotti M,Elefante GM,Lazzeri M,Guazzoni G,Casale P

更新日期：2020-06-01 00:00:00

abstract：:Current guidelines recommend conservative management as the preferred option for most low-risk prostate cancer cases, with certain possible exceptions (age <55yr, African Americans, and high-volume grade group 1). Although previous studies have documented substantial heterogeneity in the uptake of conservative managem...

journal_title：European urology

authors： Loeb S,Byrne NK,Wang B,Makarov DV,Becker D,Wise DR,Lepor H,Walter D

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Previous studies on coronavirus disease 2019 (COVID-19) have focused on populations with normal immunity, but lack data on immunocompromised populations. OBJECTIVE:To evaluate the clinical features and outcomes of COVID-19 pneumonia in kidney transplant recipients. DESIGN, SETTING, AND PARTICIPANTS:A total...

journal_title：European urology

authors： Zhu L,Gong N,Liu B,Lu X,Chen D,Chen S,Shu H,Ma K,Xu X,Guo Z,Lu E,Chen D,Ge Q,Cai J,Jiang J,Wei L,Zhang W,Chen G,Chen Z

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:A surgical adverse incident (AI) is defined as any deviation from the normal operative course. Current complication-grading systems mostly focus on postoperative events. OBJECTIVE:To propose an intraoperative AI classification (EAUiaiC) to facilitate reporting. DESIGN, SETTING, AND PARTICIPANTS:The classif...

journal_title：European urology

authors： Biyani CS,Pecanka J,Rouprêt M,Jensen JB,Mitropoulos D

更新日期：2020-05-01 00:00:00

abstract：:No data are available on the surgical safety of radical cystectomy (RC) and pelvic lymph node dissection (PLND) after the administration of checkpoint inhibitors. We aimed at reporting the first prospective rigorous assessment of perioperative outcomes after RC and extended PLND following neoadjuvant pembrolizumab in ...

journal_title：European urology

authors： Briganti A,Gandaglia G,Scuderi S,Gallina A,Colombo R,Fossati N,Barletta F,Pellegrino A,Nocera L,Montorsi F,Necchi A

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Acquiring multiparametric magnetic resonance images of the prostate is not a simple "push-button" approach. OBJECTIVE:To show how image acquisition of prostate multiparametric Magnetic Resonance Imaging (mpMRI) can be optimized. DESIGN, SETTING, AND PARTICIPANTS:Image protocols, magnetic field strength cho...

journal_title：European urology

authors： Engels RRM,Israël B,Padhani AR,Barentsz JO

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Single-port robotic surgery is being adopted for various surgical procedures. There have been interest in and clinical use of single-port robot-assisted radical prostatectomy (spRARP), but little reported data on feasibility and early outcomes. OBJECTIVE:To describe our institution's initial experience with...

journal_title：European urology

authors： Agarwal DK,Sharma V,Toussi A,Viers BR,Tollefson MK,Gettman MT,Frank I

更新日期：2020-03-01 00:00:00

abstract：CONTEXT:There have been substantial changes in the management of men with metastatic hormone-sensitive prostate cancer (mHSPC) over the past 5 yr, with upfront combination therapies replacing androgen-deprivation therapy (ADT) alone. A range of therapies have entered the space with no clear answer regarding their compa...

journal_title：European urology

authors： Sathianathen NJ,Koschel S,Thangasamy IA,Teh J,Alghazo O,Butcher G,Howard H,Kapoor J,Lawrentschuk N,Siva S,Azad A,Tran B,Bolton D,Murphy DG

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Standard management in the UK for high-risk stage 1 nonseminoma germ cell tumours of the testis (NSGCTT) is two cycles of adjuvant bleomycin, etoposide (360 mg/m2), and cisplatin (BE360P) chemotherapy, or surveillance. OBJECTIVE:To test whether one cycle of BE500P achieves similar recurrence rates to two cy...

journal_title：European urology

authors： Cullen M,Huddart R,Joffe J,Gardiner D,Maynard L,Hutton P,Mazhar D,Shamash J,Wheater M,White J,Goubar A,Porta N,Witts S,Lewis R,Hall E,111 Trial Management Group.

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:The majority of patients with overactive bladder (OAB) are aged >65yr. There has been no prospectively designed study assessing treatment efficacy with the β3-adrenoreceptor agonist, mirabegron, specifically in this age group. OBJECTIVE:A phase IV study comparing flexibly dosed mirabegron versus placebo in ...

journal_title：European urology

authors： Wagg A,Staskin D,Engel E,Herschorn S,Kristy RM,Schermer CR

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:The role of elective whole-pelvis radiotherapy (WPRT) remains controversial. Few studies have investigated it in Gleason grade group (GG) 5 prostate cancer (PCa), known to have a high risk of nodal metastases. OBJECTIVE:To assess the impact of WPRT on patients with GG 5 PCa treated with external-beam radiot...

journal_title：European urology

authors： Sandler KA,Cook RR,Ciezki JP,Ross AE,Pomerantz MM,Nguyen PL,Shaikh T,Tran PT,Stock RG,Merrick GS,Demanes DJ,Spratt DE,Abu-Isa EI,Wedde TB,Lilleby W,Krauss DJ,Shaw GK,Alam R,Reddy CA,Song DY,Klein EA,Stephenson A

更新日期：2020-01-01 00:00:00

abstract：CONTEXT:Previous studies have reported significant variation in prostate cancer rates and trends mainly due to differences in detection practices, availability of treatment, and underlying genetic susceptibility. OBJECTIVE:To assess recent worldwide prostate cancer incidence, mortality rates, and trends using up-to-da...

journal_title：European urology

authors： Culp MB,Soerjomataram I,Efstathiou JA,Bray F,Jemal A

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Metastatic castration-resistant prostate cancer (mCRPC) is the lethal form of the disease. Several recent studies have identified genomic alterations in mCRPC, but the clinical implications of these genomic alterations have not been fully elucidated. OBJECTIVE:To use whole-genome sequencing (WGS) to assess ...

journal_title：European urology

authors： Chen WS,Aggarwal R,Zhang L,Zhao SG,Thomas GV,Beer TM,Quigley DA,Foye A,Playdle D,Huang J,Lloyd P,Lu E,Sun D,Guan X,Rettig M,Gleave M,Evans CP,Youngren J,True L,Lara P,Kothari V,Xia Z,Chi KN,Reiter RE,Maher

更新日期：2019-11-01 00:00:00

abstract：CONTEXT:This overview presents the updated European Association of Urology (EAU) guidelines for non-muscle-invasive bladder cancer (NMIBC), TaT1, and carcinoma in situ (CIS). OBJECTIVE:To provide practical recommendations on the clinical management of NMIBC with a focus on clinical presentation and recommendations. E...

journal_title：European urology

authors： Babjuk M,Burger M,Compérat EM,Gontero P,Mostafid AH,Palou J,van Rhijn BWG,Rouprêt M,Shariat SF,Sylvester R,Zigeuner R,Capoun O,Cohen D,Escrig JLD,Hernández V,Peyronnet B,Seisen T,Soukup V

更新日期：2019-11-01 00:00:00

abstract：:The European Randomized study of Screening for Prostate Cancer (ERSPC) has shown a 20% relative reduction in prostate cancer mortality after 16yr [rate ratio (RR) 0.80], but centers varied by attendance, screen interval, biopsy compliance, contamination in the control arm, and treatments. We used a microsimulation mod...

journal_title：European urology

authors： Heijnsdijk EAM,Adolfsson J,Auvinen A,Roobol MJ,Hugosson J,de Koning HJ

更新日期：2019-09-01 00:00:00

abstract：:Antimuscarinics are commonly used to treat overactive bladder, but increase anticholinergic burden, which has been associated with multiple adverse outcomes in older patients. We advocate for standardization of anticholinergic risk assessment and reevaluation of anticholinergic prescribing practices for the elderly. ...

journal_title：European urology

authors： Pierce H,Thomas D,Asfaw T,Chughtai B

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Vesicovaginal fistula (VVF) is a distressing disorder in women. The transvaginal method of VVF repair is generally preferred, as its minimally invasive nature appears to offer several advantages compared with the abdominal approach, including decreased pain and blood loss and reduced hospital stay. A common ...

journal_title：European urology

authors： Luo DY,Shen H

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Active surveillance (AS) has become the recommended management strategy for men with low-risk prostate cancer. However, there is considerable uncertainty about the optimal follow-up schedule in terms of the tests to perform and their frequency. OBJECTIVE:To assess the costs and benefits of different AS foll...

journal_title：European urology

authors： Sathianathen NJ,Konety BR,Alarid-Escudero F,Lawrentschuk N,Bolton DM,Kuntz KM

更新日期：2019-06-01 00:00:00

abstract：:Results from the ERA 223 trial of abiraterone combined with radium-223 among men with chemotherapy-naïve castration-resistant prostate cancer and bone metastases show no improvement in survival free from symptomatic skeletal events. We hypothesize that this finding might be attributable to bone loss induced by the con...

journal_title：European urology

authors： Dalla Volta A,Formenti AM,Berruti A

更新日期：2019-06-01 00:00:00

abstract：CONTEXT:Current literature suggests that several pathophysiological factors and mechanisms might be responsible for the nonspecific symptom complex of overactive bladder (OAB). OBJECTIVE:To provide a comprehensive analysis of the potential pathophysiology underlying detrusor overactivity (DO) and OAB. EVIDENCE ACQUIS...

journal_title：European urology

authors： Peyronnet B,Mironska E,Chapple C,Cardozo L,Oelke M,Dmochowski R,Amarenco G,Gamé X,Kirby R,Van Der Aa F,Cornu JN

更新日期：2019-06-01 00:00:00

abstract：:The impact of biochemical recurrence (BCR) after radical treatment of prostate cancer on oncological outcomes remains unclear. A new European Association of Urology BCR risk stratification (low and high risk) has been proposed. To validate these risk groups, we retrospectively analyzed data for 1125 post-radical prost...

journal_title：European urology

authors： Tilki D,Preisser F,Graefen M,Huland H,Pompe RS

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:The extent of lymph node dissection (LND) in bladder cancer (BCa) patients at the time of radical cystectomy may affect oncologic outcome. OBJECTIVE:To evaluate whether extended versus limited LND prolongs recurrence-free survival (RFS). DESIGN, SETTING, AND PARTICIPANTS:Prospective, multicenter, phase-III...

journal_title：European urology

authors： Gschwend JE,Heck MM,Lehmann J,Rübben H,Albers P,Wolff JM,Frohneberg D,de Geeter P,Heidenreich A,Kälble T,Stöckle M,Schnöller T,Stenzl A,Müller M,Truss M,Roth S,Liehr UB,Leißner J,Bregenzer T,Retz M

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:The Rotterdam European Randomized Study of Screening for Prostate Cancer risk calculators (ERSPC-RCs) help to avoid unnecessary transrectal ultrasound-guided systematic biopsies (TRUS-Bx). Multivariable risk stratification could also avoid unnecessary biopsies following multiparametric magnetic resonance ima...

journal_title：European urology

authors： Alberts AR,Roobol MJ,Verbeek JFM,Schoots IG,Chiu PK,Osses DF,Tijsterman JD,Beerlage HP,Mannaerts CK,Schimmöller L,Albers P,Arsov C

更新日期：2019-02-01 00:00:00