Higher Risk of Fragility Fractures in Prostate Cancer Patients Treated with Combined Radium-223 and Abiraterone: Prednisone May Be the Culprit.

Abstract:

:Results from the ERA 223 trial of abiraterone combined with radium-223 among men with chemotherapy-naïve castration-resistant prostate cancer and bone metastases show no improvement in survival free from symptomatic skeletal events. We hypothesize that this finding might be attributable to bone loss induced by the concomitantly administered prednisone.

journal_name

Eur Urol

journal_title

European urology

authors

Dalla Volta A,Formenti AM,Berruti A

doi

10.1016/j.eururo.2019.01.026

subject

Has Abstract

pub_date

2019-06-01 00:00:00

pages

894-895

issue

6

eissn

0302-2838

issn

1873-7560

pii

S0302-2838(19)30069-7

journal_volume

75

pub_type

评论,社论
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