abstract：:Due to the recent advances in diagnosis and management of patients with HER2-positive breast cancer, especially through novel HER2-targeted agents, cardiotoxicity becomes an emerging problem. Although chemotherapy significantly increases survival, the risk of cardiovascular disease development is high and still undere...

journal_title：Heart failure reviews

authors： Gonciar D,Mocan L,Zlibut A,Mocan T,Agoston-Coldea L

更新日期：2021-01-06 00:00:00

abstract：:Treatment of patients with heart failure with reduced ejection fraction (HFrEF) with currently available therapies reduces morbidity and mortality. However, implementation of these therapies is a problem with only few patients achieving guideline-recommended maximal doses of therapy. In an effort to improve guideline ...

journal_title：Heart failure reviews

authors： Stienen S,Bhatt A,Ferreira JP,Vaduganathan M,Januzzi J,Adams K,Tardif JC,Rossignol P,Zannad F

更新日期：2021-01-01 00:00:00

abstract：:Transthyretin amyloid cardiomyopathy (ATTR-CM) is a progressive, life-threatening disease characterized by deposition of insoluble amyloid fibrils in the myocardium, resulting in cardiac structural and functional abnormalities and ultimately heart failure. Disease frequency is reportedly lower in women than men, but s...

journal_title：Heart failure reviews

authors： Bruno M,Castaño A,Burton A,Grodin JL

更新日期：2021-01-01 00:00:00

abstract：:Diabetes is a key independent risk factor in the development of heart failure (HF) and a strong, adverse prognostic factor in HF patients. HF remains the primary cause of hospitalisation for diabetics and, as previous studies have shown, when HF occurs in these patients, intensive glycaemic control does not directly i...

journal_title：Heart failure reviews

authors： Dutka M,Bobiński R,Ulman-Włodarz I,Hajduga M,Bujok J,Pająk C,Ćwiertnia M

更新日期：2020-11-04 00:00:00

abstract：:Depression is associated with an increased risk of death in patients with heart failure (HF); however, the association between the use of antidepressants and HF prognoses remains controversial. Therefore, this meta-analysis aimed to evaluate the effect of antidepressants on the risk of death in HF patients. We retriev...

journal_title：Heart failure reviews

authors： He W,Zhou Y,Ma J,Wei B,Fu Y

更新日期：2020-11-01 00:00:00

abstract：:Cardiac hypertrophy (CH) is generally considered adaptive responses that may occur after myocardial infarction, pressure overload, volume overload, inflammatory heart muscle disease, or idiopathic dilated cardiomyopathy, whereas long-term stimulation eventually leads to heart failure (HF). However, the current molecul...

journal_title：Heart failure reviews

authors： Sun J,Wang C

更新日期：2020-11-01 00:00:00

abstract：:We aimed to study the cardiovascular and economic burden of diabetes mellitus (DM) in patients hospitalized for heart failure (HF) in the US and to assess the recent temporal trend. Data from the National Inpatient Sample were analyzed between 2005 and 2014. The prevalence of DM increased from 40.4 to 46.5% in patient...

journal_title：Heart failure reviews

authors： Mekhaimar M,Dargham S,El-Shazly M,Al Suwaidi J,Jneid H,Abi Khalil C

更新日期：2020-09-15 00:00:00

abstract：:Cardiac fibrosis stems from the changes in the expression of fibrotic genes in cardiac fibroblasts (CFs) in response to the tissue damage induced by various cardiovascular diseases (CVDs) leading to their transformation into active myofibroblasts, which produce high amounts of extracellular matrix (ECM) proteins leadi...

journal_title：Heart failure reviews

authors： Gorabi AM,Hajighasemi S,Kiaie N,Rosano GMC,Sathyapalan T,Al-Rasadi K,Sahebkar A

更新日期：2020-09-01 00:00:00

abstract：:There was a mistake in Prof. Giuseppe Massimo Claudio Rosano's affiliation. ...

journal_title：Heart failure reviews

authors： Mascolo A,Urbanek K,De Angelis A,Sessa M,Scavone C,Berrino L,Rosano GMC,Capuano A,Rossi F

更新日期：2020-09-01 00:00:00

abstract：:Coronavirus disease 2019 (COVID-19) is due to severe acute respiratory syndrome coronavirus (SARS-CoV)-2 which binds and enters the host cells through the angiotensin-converting enzyme (ACE)2. While the potential for benefit with the use of renin-angiotensin-aldosterone system inhibitors (RAASi) and the risks from sto...

journal_title：Heart failure reviews

authors： Triposkiadis F,Starling RC,Xanthopoulos A,Butler J,Boudoulas H

更新日期：2020-09-01 00:00:00

abstract：:Cor pulmonale is the condition in which the right ventricle undergoes morphological and/or functional changes due to diseases that affect the lungs, the pulmonary circulation, or the breathing process. Depending on the speed of onset of the pathological condition and subsequent effects on the right ventricle, it is po...

journal_title：Heart failure reviews

authors： Mandoli GE,Sciaccaluga C,Bandera F,Cameli P,Esposito R,D'Andrea A,Evola V,Sorrentino R,Malagoli A,Sisti N,Nistor D,Santoro C,Bargagli E,Mondillo S,Galderisi M,Cameli M,Working group of Echocardiography of Italian Society

更新日期：2020-08-29 00:00:00

abstract：:Functional capacity represents an important predictor for cardiovascular and all-cause mortality in patients with diabetes mellitus (DM). Impaired cardiopulmonary fitness is frequently seen in DM patients, and it might partly explain morbidity and mortality in these patients. There are several potential reasons that c...

journal_title：Heart failure reviews

authors： Tadic M,Grassi G,Cuspidi C

更新日期：2020-08-15 00:00:00

abstract：:Rheumatic heart disease (RHD) is a major cause of cardiovascular morbidity and mortality in low- and middle-income countries, where living conditions promote spread of group A β-haemolytic streptococcus. Autoimmune reactions due to molecular mimicry of bacterial epitopes by host proteins cause acute rheumatic fever (A...

journal_title：Heart failure reviews

authors： Lumngwena EN,Skatulla S,Blackburn JM,Ntusi NAB

更新日期：2020-07-11 00:00:00

abstract：:Recent cardiovascular outcome trials have highlighted the propensity of the antidiabetic agents, SGLT2 inhibitors (SGLT2is or -flozin drugs), to exert positive clinical outcomes in patients with cardiovascular disease at risk for major adverse cardiovascular events (MACEs). Of interest in cardiac diabetology is the ph...

journal_title：Heart failure reviews

authors： Nashawi M,Sheikh O,Battisha A,Mir M,Chilton R

更新日期：2020-06-24 00:00:00

abstract：:There is ongoing controversy regarding the association between loop diuretics (LD), especially in high doses, and adverse clinical outcomes in outpatients with heart failure (HF). We performed a systematic review of the evidence for LD in outpatients with HF. We searched MEDLINE, EMBASE, and Cochrane Clinical Trial Co...

journal_title：Heart failure reviews

authors： Kapelios CJ,Bonou Μ,Malliaras K,Athanasiadi E,Vakrou S,Skouloudi M,Masoura C,Barbetseas J

更新日期：2020-06-21 00:00:00

abstract：:This study aimed to evaluate the diagnostic performance of echocardiographic markers of heart failure with preserved ejection fraction (HFpEF) and left ventricular diastolic dysfunction (LVDD) in comparison with the gold standard of cardiac catheterization. Diagnosing HFpEF is challenging, as symptoms are non-specific...

journal_title：Heart failure reviews

authors： Dal Canto E,Remmelzwaal S,van Ballegooijen AJ,Handoko ML,Heymans S,van Empel V,Paulus WJ,Nijpels G,Elders P,Beulens JW

更新日期：2020-06-02 00:00:00

abstract：:Previous studies have reported superiority of mechanistic target-of-rapamycin (mTOR) antagonists (mTA) over calcineurin inhibitors (CNI) as part of maintenance immunosuppression (IS) in mitigating cardiac allograft vasculopathy (CAV) after heart transplantation (HT). MEDLINE and EMBASE were searched through October 20...

journal_title：Heart failure reviews

authors： Ueyama H,Kuno T,Takagi H,Alvarez P,Asleh R,Briasoulis A

更新日期：2020-05-18 00:00:00

abstract：:According to previous epidemiological studies, we can reduce the thickness of epicardial fat and improve cardiovascular risk factors through exercise, and the changes may depend on the form of exercise. We systemically reviewed published studies that evaluated exercise intervention on epicardial adipose tissue (EAT) l...

journal_title：Heart failure reviews

authors： Colonetti T,Grande AJ,Amaral MC,Colonetti L,Uggioni ML,da Rosa MI,Hernandez AV,Tse G,Liu T,Nerlekar N,Biondi-Zoccai G,Neto MG,Durães AR,Pontes-Neto O,Resende ES,Roever L

更新日期：2020-05-16 00:00:00

abstract：:Heart failure with preserved ejection fraction (HFpEF) accounts for almost one-half of all heart failure (HF) patients and continues to increase in prevalence. While mortality with heart failure with reduced ejection fraction (HFrEF) has decreased over the past few decades with use of evidence-based HFrEF therapy, mor...

journal_title：Heart failure reviews

authors： Moustafa A,Khan MS,Alsamman MA,Jamal F,Atalay MK

更新日期：2020-05-13 00:00:00

abstract：:It is over 4 years since the Prospective Comparison of angiotensin receptor/neprilysin inhibitor (ARNI) with ACEI to Determine Impact on Global Mortality and Morbidity in Heart Failure (PARADIGM-HF) trial was published in New England Journal of Medicine. The PARADIGM-HF trial was the one that contributed to the offici...

journal_title：Heart failure reviews

authors： Książczyk M,Lelonek M

更新日期：2020-05-01 00:00:00

abstract：:Sodium glucose cotransporter 2 (SGLT2) inhibitors reduce the rate of hospitalization for heart failure in individuals with type 2 diabetes, but the underlying mechanisms remain elusive. Modestly elevated circulating β-hydroxybutyrate (βOHB) during treatment with SGLT2 inhibitors causes different beneficial effects on ...

journal_title：Heart failure reviews

authors： Hattori Y

更新日期：2020-05-01 00:00:00

abstract：:Chronic myeloid leukemia (CML) is a myeloproliferative disorder characterized by neoplastic transformation of pluripotent cells due to a typical cytogenetic and molecular mutation known as Philadelphia (Ph) chromosome. In 2001, the introduction of the tyrosine kinasis inhibitor (TKI) imatinib as a therapeutic strategy...

journal_title：Heart failure reviews

authors： Casavecchia G,Galderisi M,Novo G,Gravina M,Santoro C,Agricola E,Capalbo S,Zicchino S,Cameli M,De Gennaro L,Righini FM,Monte I,Tocchetti CG,Brunetti ND,Cadeddu C,Mercuro G

更新日期：2020-05-01 00:00:00

abstract：:The spectrum of ischemic heart diseases, encompassing acute myocardial infarction to heart failure, represents the leading cause of death worldwide. Although extensive progress in cardiovascular diagnoses and therapy has been made, the prevalence of the disease continues to increase. Cardiac regeneration has a promisi...

journal_title：Heart failure reviews

authors： Li H,Bao M,Nie Y

更新日期：2020-04-18 00:00:00

abstract：:Cardiac fibrosis is associated with non-ischemic dilated cardiomyopathy, increasing its morbidity and mortality. Cardiac fibroblast is the keystone of fibrogenesis, being activated by numerous cellular and humoral factors. Macrophages, CD4+ and CD8+ T cells, mast cells, and endothelial cells stimulate fibrogenesis dir...

journal_title：Heart failure reviews

authors： Cojan-Minzat BO,Zlibut A,Agoston-Coldea L

更新日期：2020-03-13 00:00:00

abstract：:β-Adrenergic receptors (βARs) belong to a large family of cell surface receptors known as G protein-coupled receptors (GPCRs). They are coupled to Gs protein (Gαs) for the activation of adenylyl cyclase (AC) yielding cyclic AMP (CAMP), and this provides valuable responses, which can affect the cardiac function such as...

journal_title：Heart failure reviews

authors： Ali DC,Naveed M,Gordon A,Majeed F,Saeed M,Ogbuke MI,Atif M,Zubair HM,Changxing L

更新日期：2020-03-01 00:00:00

abstract：:Dilated cardiomyopathy (DCM) represents one of the primary cardiomyopathies and may lead to heart failure and sudden death. Until recently, ventricular arrhythmias were considered to be a direct consequence of the systolic dysfunction of the left ventricle (LV) and guidelines for implantable cardioverter defibrillator...

journal_title：Heart failure reviews

authors： Zegkos T,Panagiotidis T,Parcharidou D,Efthimiadis G

更新日期：2020-02-13 00:00:00

abstract：:The prevalence of heart failure (HF), including reduced ejection fraction (HFrEF) and preserved ejection fraction (HFpEF), has increased significantly worldwide. However, the prognosis and treatment of HF are still not good. Recent studies have demonstrated that high-density lipoprotein (HDL) plays an important role i...

journal_title：Heart failure reviews

authors： Jackson AO,Meng J,Tang H,Yin K

更新日期：2020-01-27 00:00:00

abstract：:Acute heart failure hospitalizations complicated by diuretic resistance are associated with worse outcomes. Yet, quantification of the frequency and accompanying risk from loop diuretic resistance is limited by the absence of a comprehensive definition with universal clinical application. Herein, we outline limitation...

journal_title：Heart failure reviews

authors： Cox ZL,Testani JM

更新日期：2020-01-01 00:00:00

abstract：:Uric acid, the metabolic mediator of gout and urate renal stones, is associated with increased cardiovascular risk burden. Hyperuricemia is an old emerging metabolic disorder, and interaction among uric acid and cardiovascular diseases has been clearly described. Several illness including hypertension, myocardial infa...

journal_title：Heart failure reviews

authors： Borghi C,Palazzuoli A,Landolfo M,Cosentino E

更新日期：2020-01-01 00:00:00

abstract：:Myocarditis (MCD) is a type of inflammatory disease in which inflammatory cells infiltrate the myocardium, leading to cardiac dysfunction, myocardial necrosis, and fibrosis. Although it has been reported that MCD is mediated by T cells, the immune system is complex and includes many types of immune cells that interact...

journal_title：Heart failure reviews

authors： Hua X,Song J

更新日期：2019-11-01 00:00:00

abstract：:Heart failure with preserved ejection fraction (HFpEF) is a common disorder generating high mortality and important morbidity prevalence, with a very limited medical treatment available. Studies have shown that the pathophysiological hallmark of this condition is an elevated left intra-atrial pressure (LAP), exertiona...

journal_title：Heart failure reviews

authors： Burlacu A,Simion P,Nistor I,Covic A,Tinica G

更新日期：2019-09-01 00:00:00

abstract：:Heart failure (HF) is a chronic, systemic disorder that presents a serious and growing public health problem due to its high prevalence, mortality, and cost of care. Due to the aging of the population and medical advances that prolong the life of HF patients, more effective, widespread strategies for improved HF manag...

journal_title：Heart failure reviews

authors： Abu-Sawwa R,Dunbar SB,Quyyumi AA,Sattler ELP

更新日期：2019-07-01 00:00:00

abstract：:Accumulation of macrophages within the artery wall is an eminent feature of atherosclerotic plaques. Macrophages are influenced by various plaque microenvironmental stimuli, such as oxidized lipids, cytokines, and senescent erythrocytes, and thereby polarize into two main phenotypes called proinflammatory M1 and anti-...

journal_title：Heart failure reviews

authors： Momtazi-Borojeni AA,Abdollahi E,Nikfar B,Chaichian S,Ekhlasi-Hundrieser M

更新日期：2019-05-01 00:00:00

abstract：:Iron deficiency (ID) is a common and ominous comorbidity in heart failure (HF) and predicts worse outcomes, independently of the presence of anaemia. Accumulated data from animal models of systemic ID suggest that ID is associated with several functional and structural abnormalities of the heart. However, the exact ro...

journal_title：Heart failure reviews

authors： Kobak KA,Radwańska M,Dzięgała M,Kasztura M,Josiak K,Banasiak W,Ponikowski P,Jankowska EA

更新日期：2019-03-01 00:00:00

abstract：:The underlying mechanism for clinical and biochemical manifestations of chronic heart failure (HF) may be due in part to neurohumoral adaptations, such as activation of the renin-angiotensin-aldosterone and sympathetic nervous systems in the periphery and the brain. Internet search and discussion with colleagues are t...

journal_title：Heart failure reviews

authors： Singh RB,Hristova K,Fedacko J,El-Kilany G,Cornelissen G

更新日期：2019-03-01 00:00:00

abstract：:Heart failure (HF) is a clinical syndrome caused by a decline in cardiac systolic or diastolic function, which leaves the heart unable to pump enough blood to meet the normal physiological requirements of the human body. It is a serious disease burden worldwide affecting nearly 23 million patients. The concept that he...

journal_title：Heart failure reviews

authors： Chen L,Song J,Hu S

更新日期：2019-01-01 00:00:00

abstract：:Heart failure is a complex clinical syndrome associated with a significant morbidity and mortality burden. Reductions in left ventricular (LV) function trigger adaptive mechanisms, leading to structural changes within the LV and the potential development of dyssynchronous ventricular activation. This is the substrate ...

journal_title：Heart failure reviews

authors： Sieniewicz BJ,Gould J,Porter B,Sidhu BS,Teall T,Webb J,Carr-White G,Rinaldi CA

更新日期：2019-01-01 00:00:00

abstract：:Heart failure (HF) is the leading cause of hospitalization in the USA. Despite advances in pharmacologic management, the incidence of HF is on the rise and survivability is persistently reduced. Sympathetic overdrive is implicated in the pathophysiology of HF, particularly HF with reduced ejection fraction (HFrEF). Ta...

journal_title：Heart failure reviews

authors： Devgun J,Jobanputra YB,Arustamyan M,Chait R,Ghumman W

更新日期：2018-07-01 00:00:00

abstract：:Although mineralocorticoid antagonists (MRAs) have been proposed as effective fourth-line blood pressure (BP) lowering agents in resistant hypertension, this effect in heart failure is undetermined. In this synthesis of heart failure randomized controlled trials (RCTs), we evaluated the extent of BP lowering following...

journal_title：Heart failure reviews

authors： Bazoukis G,Thomopoulos C,Tse G,Tsioufis C

更新日期：2018-07-01 00:00:00

abstract：:Heart failure is a complex disease process, the manifestation of various cardiac and noncardiac abnormalities. General treatment approaches for heart failure have remained the same over the past decades despite the advent of novel therapies and monitoring modalities. In the same vein, the readmission rates for heart f...

journal_title：Heart failure reviews

authors： Njoroge JN,Cheema B,Ambrosy AP,Greene SJ,Collins SP,Vaduganathan M,Mebazaa A,Chioncel O,Butler J,Gheorghiade M

更新日期：2018-07-01 00:00:00