Abstract：
:Heart failure is a complex clinical syndrome associated with a significant morbidity and mortality burden. Reductions in left ventricular (LV) function trigger adaptive mechanisms, leading to structural changes within the LV and the potential development of dyssynchronous ventricular activation. This is the substrate targeted during cardiac resynchronisation therapy (CRT); however, around 30-50% of patients do not experience benefit from this treatment. Non-response occurs as a result of pre-implant, peri-implant and post implant factors but the technical constraints of traditional, transvenous epicardial CRT mean they can be challenging to overcome. In an effort to improve response, novel alternative methods of CRT delivery have been developed and of these endocardial pacing, where the LV is stimulated from inside the LV cavity, appears the most promising.
journal_name
Heart Fail Revjournal_title
Heart failure reviewsauthors
Sieniewicz BJ,Gould J,Porter B,Sidhu BS,Teall T,Webb J,Carr-White G,Rinaldi CAdoi
10.1007/s10741-018-9734-8subject
Has Abstractpub_date
2019-01-01 00:00:00pages
41-54issue
1eissn
1382-4147issn
1573-7322pii
10.1007/s10741-018-9734-8journal_volume
24pub_type
杂志文章,评审abstract：:Cardiotoxicity is a well-known side effect of doxorubicin (DOX), but the mechanisms leading to this phenomenon are still not completely clear. Prediction of drug-induced dysfunction onset is difficult and is still largely based on detection of cardiac troponin (cTn), a circulating marker of heart damage. In the last y...
journal_title：Heart failure reviews
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doi：10.1007/s10741-017-9653-0
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journal_title：Heart failure reviews
pub_type： 杂志文章,评审
doi：10.1007/s10741-019-09851-9
更新日期：2020-01-01 00:00:00
abstract：:Rheumatic heart disease (RHD) is a major cause of cardiovascular morbidity and mortality in low- and middle-income countries, where living conditions promote spread of group A β-haemolytic streptococcus. Autoimmune reactions due to molecular mimicry of bacterial epitopes by host proteins cause acute rheumatic fever (A...
journal_title：Heart failure reviews
pub_type： 杂志文章,评审
doi：10.1007/s10741-020-09993-1
更新日期：2020-07-11 00:00:00
abstract：:Brief ischemia to the myocardium initiates a cascade of biochemical events in cardiac myocytes that protects the heart muscle during subsequent ischemic insults. This phenomenon is called ischemic preconditioning. If an acute myocardial infarction is preceded by preinfarction angina, it results in smaller infarction s...
journal_title：Heart failure reviews
pub_type： 杂志文章,评审
doi：10.1007/s10741-007-9037-y
更新日期：2007-12-01 00:00:00
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journal_title：Heart failure reviews
pub_type： 杂志文章,评审
doi：10.1007/s10741-015-9475-x
更新日期：2015-07-01 00:00:00
abstract：:Cell transplantation is emerging as a new treatment designed tot improve the poor outcome of patients with cardiac failure. Its rationale is that implantation of contractile cells into postinfarction scars can functionally rejuvenate these areas. Primarily for practical reasons, autologous skeletal myoblasts have been...
journal_title：Heart failure reviews
pub_type： 杂志文章,评审
doi：10.1023/a:1024705214292
更新日期：2003-07-01 00:00:00
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journal_title：Heart failure reviews
pub_type： 杂志文章,评审
doi：10.1007/s10741-005-6801-8
更新日期：2004-10-01 00:00:00
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journal_title：Heart failure reviews
pub_type： 杂志文章,评审
doi：10.1007/s10741-020-09996-y
更新日期：2020-06-24 00:00:00
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journal_title：Heart failure reviews
pub_type： 杂志文章,评审
doi：10.1007/s10741-007-9002-9
更新日期：2007-03-01 00:00:00
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journal_title：Heart failure reviews
pub_type： 杂志文章,评审
doi：10.1007/s10741-018-9685-0
更新日期：2018-05-01 00:00:00
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journal_title：Heart failure reviews
pub_type： 杂志文章,评审
doi：10.1007/s10741-013-9403-x
更新日期：2014-09-01 00:00:00
abstract：:The prevalence of heart failure (HF) is increasing. A distinction is made between diastolic HF (preserved left ventricular ejection fraction (LVEF)) and systolic HF (reduced LVEF). Advanced glycation end-products (AGEs) are crystallized proteins that accumulate during ageing, but are particularly increased in patients...
journal_title：Heart failure reviews
pub_type： 杂志文章,评审
doi：10.1007/s10741-010-9225-z
更新日期：2012-03-01 00:00:00
abstract：:The evolving paradigm of heart failure has now been expanded to include the favorable neurohormonal, structural and hemodynamic profile of B-type natriuretic peptide [BNP]. As a marker of left ventricular dysfunction, BNP is a practical tool that facilitates diagnosis, contributes to prognostic evaluations and tracks ...
journal_title：Heart failure reviews
pub_type： 杂志文章,评审
doi：10.1023/a:1026107701983
更新日期：2003-10-01 00:00:00
abstract：:Due to the recent advances in diagnosis and management of patients with HER2-positive breast cancer, especially through novel HER2-targeted agents, cardiotoxicity becomes an emerging problem. Although chemotherapy significantly increases survival, the risk of cardiovascular disease development is high and still undere...
journal_title：Heart failure reviews
pub_type： 杂志文章,评审
doi：10.1007/s10741-020-10072-8
更新日期：2021-01-06 00:00:00
abstract：:Pulmonary arterial hypertension (PAH) is a subcategory of pulmonary hypertension (PH) that comprises a group of disorders with similar pulmonary vascular pathology. Though PH is common, the estimated incidence of IPAH is 1-3 cases per million, making it a rare disease. The hemodynamic definition of PAH is a mean pulmo...
journal_title：Heart failure reviews
pub_type： 杂志文章,评审
doi：10.1007/s10741-015-9510-y
更新日期：2016-05-01 00:00:00
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journal_title：Heart failure reviews
pub_type： 杂志文章,评审
doi：10.1007/s10741-012-9316-0
更新日期：2013-01-01 00:00:00
abstract：:Diabetes mellitus is a chronic disease requiring lifelong control with hypoglycemic agents that must demonstrate excellent efficacy and safety profiles. In patients taking glucose-lowering drugs, hypoglycemia is a common cause of death associated with arrhythmias, increased thrombus formation, and specific effects of ...
journal_title：Heart failure reviews
pub_type： 杂志文章,评审
doi：10.1007/s10741-017-9647-y
更新日期：2018-05-01 00:00:00
abstract：:Functional capacity represents an important predictor for cardiovascular and all-cause mortality in patients with diabetes mellitus (DM). Impaired cardiopulmonary fitness is frequently seen in DM patients, and it might partly explain morbidity and mortality in these patients. There are several potential reasons that c...
journal_title：Heart failure reviews
pub_type： 杂志文章,评审
doi：10.1007/s10741-020-10015-3
更新日期：2020-08-15 00:00:00
abstract：:It is well established that cardiac remodeling plays a pivotal role in the development of heart failure, a leading cause of death worldwide. Meanwhile, sympathetic hyperactivity is an important factor in inducing cardiac remodeling. Therefore, an in-depth understanding of beta-adrenoceptor signaling pathways would hel...
journal_title：Heart failure reviews
pub_type： 杂志文章,评审
doi：10.1007/s10741-013-9417-4
更新日期：2014-11-01 00:00:00
abstract：:Heart failure (HF) is a common complication in patients with type 2 diabetes and it is closely associated with high morbidity and mortality rate. The incidence of cardiovascular events in patients with diabetes is related to high levels of glycemia, expressed by increase of HbA1c levels. However, there is little evide...
journal_title：Heart failure reviews
pub_type： 杂志文章,评审
doi：10.1007/s10741-018-9669-0
更新日期：2018-05-01 00:00:00
abstract：:Diabetes is a global epidemic and a leading cause of death with more than 422 million patients worldwide out of whom around 392 million alone suffer from type 2 diabetes (T2D). Sodium-glucose cotransporter 2 inhibitors (SGLT2i) are novel and effective drugs in managing glycemia of T2D patients. These inhibitors gained...
journal_title：Heart failure reviews
pub_type： 杂志文章,评审
doi：10.1007/s10741-017-9665-9
更新日期：2018-05-01 00:00:00
abstract：:Heart failure with preserved ejection fraction (HFpEF) accounts for almost one-half of all heart failure (HF) patients and continues to increase in prevalence. While mortality with heart failure with reduced ejection fraction (HFrEF) has decreased over the past few decades with use of evidence-based HFrEF therapy, mor...
journal_title：Heart failure reviews
pub_type： 杂志文章,评审
doi：10.1007/s10741-020-09958-4
更新日期：2020-05-13 00:00:00
abstract：:Objective and validated measures of depression/distress (anxiety and anger) are available and readily usable at the bedside or in clinic. Foremost among these is the Patient's Health Questionnaire--an adaptation of DSM IV criteria for Major Depressive Disorder that permits administration and scoring by nursing or phys...
journal_title：Heart failure reviews
pub_type： 杂志文章,评审
doi：10.1007/s10741-007-9046-x
更新日期：2009-03-01 00:00:00
abstract：:Heart failure (HF) is a chronic, systemic disorder that presents a serious and growing public health problem due to its high prevalence, mortality, and cost of care. Due to the aging of the population and medical advances that prolong the life of HF patients, more effective, widespread strategies for improved HF manag...
journal_title：Heart failure reviews
pub_type： 杂志文章,评审
doi：10.1007/s10741-019-09781-6
更新日期：2019-07-01 00:00:00
abstract：:The discovery of cardiac natriuretic peptides two decades ago has lead to considerable research to investigate their biochemical and physiological properties. Clearly the heart is not just a pump but is also an endocrine organ that together with the kidneys control volume overload. The natriuretic peptides are a group...
journal_title：Heart failure reviews
pub_type： 杂志文章,评审
doi：10.1023/a:1026182912461
更新日期：2003-10-01 00:00:00
abstract：:In this paper, two different aspects of the relationship between chronic kidney disease and sudden cardiac death (SCD) have been reviewed. In end-stage renal disease patients, SCD risk is increased, and among patients implanted with a cardioverter defibrillator (ICD), dialysed ones carry a superior relative risk compa...
journal_title：Heart failure reviews
pub_type： 杂志文章,评审
doi：10.1007/s10741-010-9210-6
更新日期：2011-11-01 00:00:00
abstract：BACKGROUND:Transient left ventricular apical ballooning syndrome also called Tako-Tsubo cardiomyopathy is defined as a syndrome consisting of stress induced apical ballooning of the left ventricle and normal coronary arteries. The majority of the published reports are case reports or case series with a small number of ...
journal_title：Heart failure reviews
pub_type： 杂志文章,meta分析
doi：10.1007/s10741-005-8555-8
更新日期：2005-12-01 00:00:00
abstract：:Heart failure (HF) is associated with a high morbidity and mortality in the Western World. Our knowledge of the epidemiology, pathophysiology, and therapy has improved dramatically during the last 20 years. Pharmacological treatment, as it stands today, is a combination of preventive and symptomatic strategies. The ma...
journal_title：Heart failure reviews
pub_type： 杂志文章,评审
doi：10.1007/s10741-006-9482-z
更新日期：2006-06-01 00:00:00
abstract：:Descriptions of the pathophysiology of heart failure have gone through a substantial evolution in the last 50 years. It is now recognised that heart failure can occur in the presence and also in the absence of a reduction in left ventricular function. In the former situation, this classically has been described to lea...
journal_title：Heart failure reviews
pub_type： 杂志文章,评审
doi：10.1007/s10741-012-9344-9
更新日期：2013-07-01 00:00:00
abstract：BACKGROUND:Whether mechanical restraint of the left ventricle (LV) can influence remodeling following myocardial infarction (MI) remains poorly understood. The following discussion details three studies examining the effects of surgically placing a cardiac support device (CSD) over the entire epicardial surface, on inf...
journal_title：Heart failure reviews
pub_type： 杂志文章
doi：10.1007/s10741-005-4640-2
更新日期：2005-06-01 00:00:00
