abstract：BACKGROUND: The support group "Arbeitskreis der Pankreatektomierten e. V. (AdP)" was founded in 1976 and is the largest group of individuals affected by pancreatic disease in Germany. Members of the AdP support patients with pancreatic disease. This patient-initiated, cross-sectional study intends to present the result...

journal_title：Zeitschrift fur Gastroenterologie

authors： Dimopoulos I,Meyer G,Elhabash SI,Sorleto M,Gartung C,Ewald N,Fetzner UK,Otto L,Möhlenbrock F,Uhl W,Gerdes B

更新日期：2021-01-27 00:00:00

abstract：:Infections caused by pathogens of the Mycobacterium tuberculosis complex, i. e., tuberculosis (TB), and the non-infectious, autoimmune disease sarcoidosis are among the most common granulomatous diseases worldwide. Typically, the lung is the primary site of infection and manifestation, respectively which makes the two...

journal_title：Zeitschrift fur Gastroenterologie

authors： Gernert JA,Sirtl S,Macke L,Wittmann E,Strueven AK,Schwarze V,Dichtl K,Neumann J,Mayerle J,Schulz C

更新日期：2021-01-01 00:00:00

abstract：AIM: To investigate feasibility and outcome the novel and favorable option of an endoscopic ultrasonography(EUS)-guided antegrade or even retrograde gall stone extraction via a transhepatic route in patients (pats.) with no option for the usual gold standard, ERCP. MATERIAL/METHODS: All consecutive pats. with cholangi...

journal_title：Zeitschrift fur Gastroenterologie

authors： Fueldner F,Meyer F,Will U

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND: Verrucous carcinoma of the esophagus is a rare disease leading to dysphagia, chest pain, and weight loss. The diagnosis is difficult because even repeated biopsies are often without tumor evidence. We present a patient with verrucous carcinoma of the esophagus and a literature review. CASE REPORT: A 64-yea...

journal_title：Zeitschrift fur Gastroenterologie

authors： Frieling T,Kreysel C,Blank M,Müller D,Euler P,Melchior I,Wullstein C,Hemmerlein B

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND: More and more gastroenterologists are not satisfied with their working conditions and run the risk of developing burnout symptoms. Little is known about the job satisfaction and burnout risk among physicians working in endoscopy units in Germany. This study examines the risk of burnout and job satisfaction ...

journal_title：Zeitschrift fur Gastroenterologie

authors： Adarkwah CC,Labenz J,Birkner B,Beilenhoff U,Hirsch O

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND: The aim of our study is to analyze viscosity characteristics of focal liver lesions (FLLs) and the diagnostic performance of shear wave dispersion (SWD) in differentiating benign and malignant FLLs. METHODS: Between January 2018 and April 2018, 58 consecutive patients (median age 57, age range 21-74 years,...

journal_title：Zeitschrift fur Gastroenterologie

authors： Dong Y,Qiu Y,Zhang Q,Yang D,Yu L,Wang WP,Dietrich CF

更新日期：2020-09-01 00:00:00

abstract：:The primary aim of the Prä-GIT study is to collect information on the prevalence and course of precancerous and early malignant lesions in the upper GIT (uGIT) as well as risk factors associated with these lesions in asymptomatic individuals. Study participants presenting for a screening colonoscopy will undergo an ad...

journal_title：Zeitschrift fur Gastroenterologie

authors： Ebigbo A,Römmele C,Meisinger C,Probst A,Beyer A,Arnold J,Beer F,Endlicher E,Schiffelholz W,Linseisen J,Messmann H

更新日期：2020-08-01 00:00:00

abstract：:Die COVID-19-Pandemie ist ein weltweiter Ausbruch von neu aufgetretenen Infektionen mit dem SARS-CoV-2-Virus, von denen weltweit derzeit mehr als 10.670.000 Menschen erkrankt sind bzw. waren. In Deutschland leiden ca. 450.000 Patienten an einer chronisch entzündlichen Darmerkrankung; diese Patienten benötigen in der R...

journal_title：Zeitschrift fur Gastroenterologie

authors： Autoren.,Collaborators:.

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND: Hepatic encephalopathy (HE) is a severe complication of liver cirrhosis with impairment of quality of life and prognosis. Management patterns among physicians have not been investigated yet. METHODS: A questionnaire containing 17 questions was sent out to 1468 gastroenterologists and 120 general practition...

journal_title：Zeitschrift fur Gastroenterologie

authors： Labenz C,Adarkwah CC,Wörns MA,Miehlke S,Hofmann WP,Buggisch P,Galle PR,Frieling T,Labenz J

更新日期：2020-01-01 00:00:00

abstract：:Increasing numbers of active tuberculosis in Germany were recorded in the last years. Thus, also extrapulmonary manifestations of tuberculosis gain clinical significance as differential diagnoses, especially when a metastatic tumor disease is suspected. We report the case of a 77-year-old male patient who presented wi...

journal_title：Zeitschrift fur Gastroenterologie

authors： Voit FM,Abdelhafez M,Rothe K,Slotta-Huspenina J,Gaa J,Schmid RM,Spinner CD

更新日期：2019-12-01 00:00:00

abstract：:Portal hypertension in patients with liver cirrhosis can be improved, not only by surgical or interventional shunt placements, but also by drug-only treatment. Many recent studies addressed the question whether any of these substances can improve survival of patients with liver cirrhosis when administered continuously...

journal_title：Zeitschrift fur Gastroenterologie

authors： Holstege A

更新日期：2019-08-01 00:00:00

abstract：OBJECTIVES: This study aimed to describe biologic treatment of German inflammatory bowel disease (IBD) patients, including biologics' dosage, health care resource use, and treatment-associated cost. METHODS: In this retrospective claims data analysis, all continuously insured adult IBD patients (Crohn's disease [CD] o...

journal_title：Zeitschrift fur Gastroenterologie

authors： Brandes A,Groth A,Gottschalk F,Wilke T,Ratsch BA,Orzechowski HD,Fuchs A,Deiters B,Bokemeyer B

更新日期：2019-07-01 00:00:00

abstract：:This guideline provides evidence-based key recommendations for diagnosis and therapy of complications of liver cirrhosis and upgrades the 2011 version. An interdisciplinary team of medical experts and patient support groups developed the guideline following the AWMF recommendations for evidence based consensus guideli...

journal_title：Zeitschrift fur Gastroenterologie

authors： Gerbes AL,Labenz J,Appenrodt B,Dollinger M,Gundling F,Gülberg V,Holstege A,Lynen-Jansen P,Steib CJ,Trebicka J,Wiest R,Zipprich A,Deutsche Gesellschaft für Allgemein- und Viszeralchirurgie (DGAV).,Deutsche Gesellschaft für Inner

更新日期：2019-05-01 00:00:00

abstract：:Hepatocellular carcinomas (HCC) that extend into the vena cava and the right atrium have a poor prognosis. Surgical approaches including partial hepatectomy and thrombectomy are the most frequently reported treatment options. However, most patients with advanced HCC are not eligible for complex surgical interventions ...

journal_title：Zeitschrift fur Gastroenterologie

authors： Zhan T,Sollors J,Steinebrunner N,Schlitt HJ,Stroszczynski C,Weiss KH,Ebert MP,Teufel A

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND: Eosinophilic esophagitis (EoE) is detected frequently in dysphagia and noncardiac chest pain. Management of patients with EoE may be complicated because EoE is associated frequently with esophageal motility disorders. We present the rare case of esophageal achalasia (EA) associated with eosinophilic infiltr...

journal_title：Zeitschrift fur Gastroenterologie

authors： Frieling T,Heise J,Kreysel C,Blank M,Hemmerlein B,Beccu L,Kuhlbusch-Zicklam R

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND: More than 250 000 patients suffer from chronic hepatitis C in Germany. Several potent, direct-acting antiviral drugs have been approved since 2014. The aim of the German Hepatitis C-Registry (DHC-R) is to describe the epidemiology and patient care of hepatitis C and to investigate the efficacy and safety of...

journal_title：Zeitschrift fur Gastroenterologie

authors： Hüppe D,Serfert Y,Buggisch P,Mauss S,Böker KHW,Müller T,Klinker H,Günther R,Berg T,Cornberg M,Niederau C,Sarrazin C,Simon KG,Zeuzem S,Manns MP,Wedemeyer H

更新日期：2019-01-01 00:00:00

abstract：:Patients with chronic inflammatory bowel disease (IBD) have a significantly increased risk of clinically relevant clostridial infection (CDI). In turn, CDI can increase IBD activity. Therefore, rapid diagnosis and therapy is required. Many diagnostic and treatment studies on patients with CDI without inflammatory bowe...

journal_title：Zeitschrift fur Gastroenterologie

authors： Stallmach A,Reuken PA,Teich N

更新日期：2018-11-01 00:00:00

abstract：:Increased acid reflux after meals is a key feature of gastro-esophageal reflux disease (GERD) and is the most important cause for patient symptoms, particularly heartburn and acid regurgitation. Chronic acid exposure also predisposes to associated pathologies including reflux esophagitis, esophageal stricture, Barrett...

journal_title：Zeitschrift fur Gastroenterologie

authors： Sauter M,Fox MR

更新日期：2018-10-01 00:00:00

abstract：INTRODUCTION: Assessment of disease activity in Crohn's disease (CD) and ulcerative colitis (UC) is usually based on the physician's evaluation of clinical symptoms, endoscopic findings, and biomarker analysis. The German Inflammatory Bowel Disease Activity Index for CD (GIBDICD) and UC (GIBDIUC) uses data from patient...

journal_title：Zeitschrift fur Gastroenterologie

authors： Hüppe A,Langbrandtner J,Häuser W,Raspe H,Bokemeyer B

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:With regard to quality of life and organ shortage, follow-up after liver transplantation (LT) should consider risk factors for allograft failure in order to avoid the need for re-LT and to improve the long-term outcome of recipients. Therefore, the aim of this study was to explore potential risk factors for ...

journal_title：Zeitschrift fur Gastroenterologie

authors： Huesing-Kabar A,Dohna CZ,Heinzow H,Cicinnati VR,Beckebaum S,Schmidt M,Gerth HU,Pohlen M,Wilms C,Palmes D,Schmidt HH,Kabar I

更新日期：2018-07-01 00:00:00

abstract：:Pancreatic cancer is one of the most lethal cancer diseases. For years, gemcitabine has been the standard of care and the only therapeutic option in patients with metastatic pancreatic cancer. Within the last years, new combination therapies have been established for first-line treatment, which significantly improve o...

journal_title：Zeitschrift fur Gastroenterologie

authors： Waidmann O,Pelzer U,Boeck S,Waldschmidt DT

更新日期：2018-06-01 00:00:00

abstract：INTRODUCTION:Gallstones are rarely mentioned in the medical texts of antiquity. The physician, Alexander of Tralles mentions-for the first time-stones in the gallbladder as a possible cause for obstructive jaundice. This designation is found in his textbook on medicine under the heading "obstruction of the liver". Base...

journal_title：Zeitschrift fur Gastroenterologie

authors： Ursin F,Steger F

更新日期：2018-03-01 00:00:00

abstract：:Introduction The common mastocytosis variant systemic mast cell activation syndrome (MCAS) may underlie at least a subset of patients with irritable bowel syndrome (IBS). A critical role of vitamin D (VD) in the stabilization of mast cells (MCs) with deficiency of VD resulting in MC activation has been demonstrated. I...

journal_title：Zeitschrift fur Gastroenterologie

authors： Wirz S,Hertfelder HJ,Seidel H,Homann J,Molderings GJ

更新日期：2017-12-01 00:00:00

abstract：:We report the case of a 70-year-old man who presented with hematochezia, anaemia, and severe abdominal pain 6 days after polypectomy. Contrast-enhanced ultrasound and computed tomography revealed no signs of free intra-abdominal air but showed intra-abdominal and intra-luminal bleeding. The patient was referred to col...

journal_title：Zeitschrift fur Gastroenterologie

authors： Neesse A,Grade M,Dango S,Ghadimi M,Ellenrieder V,Kunsch S,Amanzada A

更新日期：2017-10-01 00:00:00

abstract：:Proton pump inhibitors are among the most commonly used drugs worldwide. They are considered to be largely safe and cause little side-effects. We report a 69-year-old woman who suffered from erythematous plaques 2 months after initiating therapy with esomeprazole. The diagnosis of subacute cutaneous lupus erythematosu...

journal_title：Zeitschrift fur Gastroenterologie

authors： Gliem N,Broekaert SMC,Seitz CS,Schön MP,Ellenrieder V

更新日期：2017-09-01 00:00:00

abstract：:Gastric cancer and cancer of the oesophagogastric junction is diagnosed in the locally advanced or metastatic setting in 55 - 65 % of the cases and is generally treated with perioperative or palliative chemotherapy. For patients with metastatic disease, it is important to reliably determine the HER2 status for potenti...

journal_title：Zeitschrift fur Gastroenterologie

authors： Gaiser T,Hirsch D,Hofheinz RD

更新日期：2017-09-01 00:00:00

abstract：:Leptomeningeal carcinomatosis is a rare but serious complication of solid tumors such as melanoma, breast and lung cancer, as well as gastrointestinal carcinomas. Its clinical manifestation is highly variable, presenting as radicular pain with or without neurological deficits, as well as with headaches and hallucinato...

journal_title：Zeitschrift fur Gastroenterologie

authors： Höblinger A,Weber S,Tschirner F,Kröber S,Streetz K

更新日期：2017-07-01 00:00:00

abstract：:The term cholangiocarcinoma (CCA) comprises neoplasms of the intrahepatic, perihilar, and distal bile duct. Five-year survival rates of patients with CCA are below 20 %, and no targeted therapy could prove a benefit in comparison to the standard treatment of cisplatinum and gemcitabine. In recent years, next generatio...

journal_title：Zeitschrift fur Gastroenterologie

authors： Walter D,Hartmann S,Waidmann O

更新日期：2017-06-01 00:00:00

abstract：:Background and aims Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death worldwide. Infection with the hepatitis C virus (HCV) is one of the most frequent underlying diseases leading to HCC development. Sorafenib is the standard of care for HCC patients not amenable to local treatment, r...

journal_title：Zeitschrift fur Gastroenterologie

authors： Waidmann O,Peveling-Oberhag J,Eichler K,Schulze F,Vermehren J

更新日期：2017-06-01 00:00:00

abstract：:Patients with hepatocellular carcinoma (HCC) in cirrhosis have an increased risk for postoperative complications including liver failure. However, there is some evidence that the use of laparoscopy markedly decreases this risk. Patients Between 2010 - 2015, a total of 21 laparoscopic liver resections were performed fo...

journal_title：Zeitschrift fur Gastroenterologie

authors： Seehofer D,Sucher R,Schmelzle M,Öllinger R,Lederer A,Denecke T,Schott E,Pratschke J

更新日期：2017-05-01 00:00:00

abstract：:Background and aims Therapy of hepatocellular carcinoma (HCC) mainly depends on tumor stage and liver function. The aim of this study was to identify additional predictors of overall survival in HCC patients with a particular attention to multimodal therapies. Methods Six hundred and seven consecutive HCC-patients tre...

journal_title：Zeitschrift fur Gastroenterologie

authors： Göbel T,Graf D,Hosnowsky C,Blondin D,Knoefel WT,Häussinger D,Erhardt A

更新日期：2017-03-01 00:00:00

abstract：:Introduction and aims High-resolution esophageal manometry (HRM) has improved the diagnostic work-up of esophageal motility disorders. Simultaneous evaluation of bolus clearance delivers useful information about the function of tubular esophagus. We assessed bolus clearance in a combined HRM-impedance examination for ...

journal_title：Zeitschrift fur Gastroenterologie

authors： Zizer E,Seufferlein T,Hänle MM

更新日期：2017-02-01 00:00:00

abstract：:Background: Acute hepatitis B virus (HBV) infection is still a major cause of acute liver failure (ALF), necessitating a high rate of emergency liver transplantation (LTx). Acute infection is followed by high viral replication rates leading to hepatocyte death and, ultimately, ALF. The objective of treating HBV-induce...

journal_title：Zeitschrift fur Gastroenterologie

authors： Jochum C,Maischack F,Anastasiou OE,Verheyen J,Timm J,Bechmann L,Gerken G,Canbay A

更新日期：2016-12-01 00:00:00

abstract：:Fecal microbiota transplantation has gathered much attention due to its high efficacy in resolving recurrent Clostridium difficile infection. Until today, it is recognized as a safe procedure without any severe side effects. Patients with impaired conscious states suffering from recurrent episodes of aspiration are at...

journal_title：Zeitschrift fur Gastroenterologie

authors： Goeser F,Schlabe S,Ruiner CE,Kramer L,Strassburg CP,Spengler U

更新日期：2016-10-01 00:00:00

abstract：:Diagnosis of oesophageal motility disorders has been well established for many years now, although circadian gastrointestinal motility is still purely understood. So far, high-resolution manometry (HRM) is only available for short-term measurement in clinical practice to evaluate simultaneous pressure conditions throu...

journal_title：Zeitschrift fur Gastroenterologie

authors： Jell A,Wilhelm D,Ostler D,Feußner H,Hüser N

更新日期：2016-09-01 00:00:00

abstract：PURPOSE:In hepatic resections, there has been a high quality demand. The aim of this systematic clinical, prospective, unblinded unicenter observational study with two arms in an unselected patient cohort was to investigate whether hemostat device can significantly improve outcome in resective liver surgery, in particu...

journal_title：Zeitschrift fur Gastroenterologie

authors： Petersen M,Steinert R,Jannasch O,Venerito M,Meissner C,Kropf S,Albrecht R,Lippert H,Meyer F

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Changes in gastric and small bowel motility are a common clinical problem. Currently diagnostic options are limited because each method harbors certain disadvantages. It has been shown that the high-resolution three-dimensional magnetic detector system 3D-MAGMA is capable of reliably measuring gastric and sm...

journal_title：Zeitschrift fur Gastroenterologie

authors： Jacob VY,Stallmach A,Felber J

更新日期：2016-06-01 00:00:00

abstract：INTRODUCTION:Clinical trials and health services research are crucial pillars for improving patient care. This paper examines factors inhibiting and promoting the study activity and the knowledge and use of trial registries (e. g. DRKS, StudyBox) as an opportunity to learn about existing studies. MATERIAL AND METHODS:...

journal_title：Zeitschrift fur Gastroenterologie

authors： Kowalski C,Ferencz J,Benz S,Post S,Seufferlein T,Stinner B,Penzes O,Wesselmann S

更新日期：2016-05-01 00:00:00

abstract：:Appendico-ileal knotting is a very rare and widely unknown cause of closed loop bowel obstruction. In most cases it is discovered incidentally during surgery. We report a 59 year old female with a previous history of a total abdominal hysterectomy who presented with features of intestinal obstruction and was thought t...

journal_title：Zeitschrift fur Gastroenterologie

authors： Okello M,Kharono B,Mwaka E,Lock G

更新日期：2016-04-01 00:00:00

abstract：:The high regenerative potential of the liver is driven by parenchymal and non-parenchymal cells, which restore the original liver mass after injury by cell proliferation. The contribution of stem- and progenitor cells to liver regeneration is mainly observed when hepatocyte proliferation is impaired. However, the orig...

journal_title：Zeitschrift fur Gastroenterologie

authors： Kordes C,Sawitza I,Götze S,Schumacher E,Häussinger D

更新日期：2015-12-01 00:00:00