Update on cholangiocarcinoma: potential impact of genomic studies on clinical management.

abstract：:Background: Acute hepatitis B virus (HBV) infection is still a major cause of acute liver failure (ALF), necessitating a high rate of emergency liver transplantation (LTx). Acute infection is followed by high viral replication rates leading to hepatocyte death and, ultimately, ALF. The objective of treating HBV-induce...

journal_title：Zeitschrift fur Gastroenterologie

authors： Jochum C,Maischack F,Anastasiou OE,Verheyen J,Timm J,Bechmann L,Gerken G,Canbay A

更新日期：2016-12-01 00:00:00

abstract：:Liver fibrosis is the final common pathway in a variety of liver diseases. To model liver fibrosis in mice is important as mechanisms not only of fibrogenesis, but also of fibrolysis, need to be clearly defined. Also, small rodents present a possibility to test potential treatments in vivo. Today, there are several mo...

journal_title：Zeitschrift fur Gastroenterologie

authors： Weiler-Normann C,Herkel J,Lohse AW

更新日期：2007-01-01 00:00:00

abstract：:Measurement of chromogranin A (CgA) level in blood can be used to monitor neuroendocrine tumours. However CgA level may also be elevated in several other endocrine and non-endocrine diseases. Here, we report on a patient with an incidental left-sided adrenal tumour and elevated CgA level. Adrenalectomy did not confirm...

journal_title：Zeitschrift fur Gastroenterologie

authors： Wiedmann MW,Mössner J,Stumvoll M,Führer D

更新日期：2009-07-01 00:00:00

abstract：:The following publication is an overview looking at diagnostic and therapeutic possibilities related to interventional procedures for diseases of the pancreas. We emphasize the description of the technique and show meaningful indications and limitations. ...

journal_title：Zeitschrift fur Gastroenterologie

authors： Tomczak RJ,Görich J,Gabelmann A,Krämer S,Rilinger N,Brambs HJ

更新日期：2000-11-01 00:00:00

abstract：:The mechanism of the diarrheogenic effect of bile acids and fatty acids is incompletely understood. In order to study their effects on motility we tested sodium deoxycholate and sodium ricinoleate in their actions on the spontaneous mechanical and myoelectrical activity of the isolated circular muscle of the cat colon...

journal_title：Zeitschrift fur Gastroenterologie

authors： Wienbeck M,Karaus M

更新日期：1983-08-01 00:00:00

abstract：BACKGROUND:Helicobacter pylori is a human pathogen that causes chronic gastritis and peptic ulcers. Epidemiological studies demonstrated that individuals who are blood group 0 positive or represent non-secretors of their blood group antigens are more likely to develop peptic ulcers. The Lewis(b) blood group antigen has...

journal_title：Zeitschrift fur Gastroenterologie

authors： Keller R,Dinkel KC,Christl SU,Fischbach W

更新日期：2002-05-01 00:00:00

abstract：:Gastrointestinal stromal tumours (GIST) occur mostly as sporadic solitary lesions involving the tubular GI tract and are only rarely associated with other benign or malignant neoplasms or occur as part of a multi-neoplastic disease as in the setting of Carney's triad and von Recklinghausen's disease. We analysed a tot...

journal_title：Zeitschrift fur Gastroenterologie

authors： Agaimy A,Wuensch PH

更新日期：2005-09-01 00:00:00

abstract：:12% of the rectal biopsies (19% of the patients) showed epitheloid cell granulomas in clinically definite Crohn's disease. In colonic biopsies such granulomata were visible in 14% (22% of the patients). Granulomata were scarcely seen in normal or slightly inflamed mucosa. They were mostly found together with crypt abs...

journal_title：Zeitschrift fur Gastroenterologie

authors： Schmitz-Moormann P,Malchow H,Miller B,Brandes JW

更新日期：1979-05-01 00:00:00

abstract：:Endoscopic sclerotherapy to stop acute gastrointestinal haemorrhage is simple as well as inexpensive in comparison to laser or electrocoagulation. In this paper a report on our experiences during the last five years is given. 187 patients with different bleeding sites in the upper and lower digestive tract have been t...

journal_title：Zeitschrift fur Gastroenterologie

authors： Soehendra N

更新日期：1983-06-01 00:00:00

abstract：:A case report is given on two patients receiving halothane anesthesia while beeing treated with isoniacid, ethambutol and rifampicin. Following halothane anesthesia, both patients developed a severe liver disease with encephalopathy grade III. We observed a moderate increase of bilirubin and SGOT and a more severe inc...

journal_title：Zeitschrift fur Gastroenterologie

authors： Schmidt-Wilcke HA,Wolfert W,Grundmann E

更新日期：1977-08-01 00:00:00

abstract：:Patients with hepatocellular carcinoma (HCC) in cirrhosis have an increased risk for postoperative complications including liver failure. However, there is some evidence that the use of laparoscopy markedly decreases this risk. Patients Between 2010 - 2015, a total of 21 laparoscopic liver resections were performed fo...

journal_title：Zeitschrift fur Gastroenterologie

authors： Seehofer D,Sucher R,Schmelzle M,Öllinger R,Lederer A,Denecke T,Schott E,Pratschke J

更新日期：2017-05-01 00:00:00

abstract：:In 19 patients with gastrointestinal tumors the diagnosis was made by ultrasound. 7 patients were examined for further investigation of an abdominal mass; 12 patients, presented with symptoms suggesting malignants, e. g. weight loss, vomiting, fever, abdominal pain, and/or anaemia from bloodloss were first investigate...

journal_title：Zeitschrift fur Gastroenterologie

authors： Schwerk WB,Braun B

更新日期：1978-07-01 00:00:00

abstract：:We report a rare case of a 52 year old patient with multiple gastric wall abscesses. In 1987 a selective proximal vagotomy was performed. Because of non-specific gastric symptoms in 1993 an endoscopy and an endoscopic ultrasound was performed at another hospital which resulted in the likely diagnosis of multiple leiom...

journal_title：Zeitschrift fur Gastroenterologie

authors： Messmann H,Hollerbach S,Gross V,Holstege A,Büttner R,Schmidt J,Hohenberger W,Schölmerich J

更新日期：1995-03-01 00:00:00

abstract：:The distribution of class I (A, B, C) and class II (DR antigens) histocompatibility antigens (HLA) was examined in 82 patients with hepatocellular carcinoma (HCC) and in 147 patients with chronic liver disease as controls. The diagnosis of HCC was confirmed by histological examination of liver tissue. HLA-B15 antigen ...

journal_title：Zeitschrift fur Gastroenterologie

authors： Golubovic G,Stajic M,Stolic I,Nikolic JA,Neskovic AN,Pandey L

更新日期：1996-01-01 00:00:00

abstract：:In a randomized placebo-controlled parallel and double-blind study the gastroduodenal effects of 20 mg piroxicam daily was evaluated endoscopically in the presence of ranitidine 150 mg bid or 300 mg bid in 31 healthy volunteers. Drugs were taken over a period of 14 days. Endoscopies were performed at entry and repeate...

journal_title：Zeitschrift fur Gastroenterologie

authors： Müller P,Leucht U,Simon B

更新日期：1992-12-01 00:00:00

abstract：:Implantation of the ureters in the sigma is practicable as far as cystectomy or congential malformations are concerned. The problem of the development of sigma-rectum polyps following ureterosigmoidostomy (uss) is being discussed within the description of three own case reports. The polyp of our first case is classif...

journal_title：Zeitschrift fur Gastroenterologie

authors： Köpp W,Dienes HP,Schmidt R

更新日期：1980-03-01 00:00:00

abstract：:A 29-year-old man presented with abdominal cramps and bloody diarrhoea. Blood tests revealed elevated C-reactive protein (21.3 mg/dL; normal range 0.01 - 0. 82 mg/dL) and white blood cells (28200/μL, normal range 4000 - 10000/μL). Stool tests were negative for enteropathogenic bacteria and Clostridium difficile toxins...

journal_title：Zeitschrift fur Gastroenterologie

authors： Scheppach W,Reissmann N,Breunig E,Konwisorz A,Schwarz TF,Müller JG,Tappe D

更新日期：2012-02-01 00:00:00

abstract：:The amino acid consumption test (AACT) during exogenous stimulation with secretin and CCK was proposed as a sensitive and highly specific test for detection of exocrine pancreatic insufficiency. To further investigate the diagnostic value of this test we measured the AACT in comparison with the pancreolauryl serum tes...

journal_title：Zeitschrift fur Gastroenterologie

authors： Kemmer TP,Malfertheiner P,Häberle H,Pohlandt F,Friess H,Büchler M,Ditschuneit H

更新日期：1992-06-01 00:00:00

abstract：:Background and aims Therapy of hepatocellular carcinoma (HCC) mainly depends on tumor stage and liver function. The aim of this study was to identify additional predictors of overall survival in HCC patients with a particular attention to multimodal therapies. Methods Six hundred and seven consecutive HCC-patients tre...

journal_title：Zeitschrift fur Gastroenterologie

authors： Göbel T,Graf D,Hosnowsky C,Blondin D,Knoefel WT,Häussinger D,Erhardt A

更新日期：2017-03-01 00:00:00

abstract：:Iatrogenic perforation of the upper gastrointestinal tract is one of the most serious complications of upper gastrointestinal endoscopy, with high rates of morbidity and mortality. Treatment is challenging because stent placement or surgical repair of the perforation in this area is often impossible. We report on two ...

journal_title：Zeitschrift fur Gastroenterologie

authors： Möschler O,Müller MK

更新日期：2014-03-01 00:00:00

abstract：:This guideline provides evidence-based key recommendations for diagnosis and therapy of complications of liver cirrhosis and upgrades the 2011 version. An interdisciplinary team of medical experts and patient support groups developed the guideline following the AWMF recommendations for evidence based consensus guideli...

journal_title：Zeitschrift fur Gastroenterologie

authors： Gerbes AL,Labenz J,Appenrodt B,Dollinger M,Gundling F,Gülberg V,Holstege A,Lynen-Jansen P,Steib CJ,Trebicka J,Wiest R,Zipprich A,Deutsche Gesellschaft für Allgemein- und Viszeralchirurgie (DGAV).,Deutsche Gesellschaft für Inner

更新日期：2019-05-01 00:00:00

abstract：:The high regenerative potential of the liver is driven by parenchymal and non-parenchymal cells, which restore the original liver mass after injury by cell proliferation. The contribution of stem- and progenitor cells to liver regeneration is mainly observed when hepatocyte proliferation is impaired. However, the orig...

journal_title：Zeitschrift fur Gastroenterologie

authors： Kordes C,Sawitza I,Götze S,Schumacher E,Häussinger D

更新日期：2015-12-01 00:00:00

abstract：:During the last years the per-capita-consumption of pure alcohol in the Federal Republic of Germany is slightly decreasing. In 1986 every person consumed an average of 11.5 litres of pure alcohol (146.4 litres of beer, 23.3 litres of wine and 6.1 litres of spirits). The amount of the alcohol addicts must be estimated ...

journal_title：Zeitschrift fur Gastroenterologie

authors： Ziegler H

更新日期：1988-10-01 00:00:00

abstract：:Chronic hepatitis C virus infection can be associated with mixed cryoglobulinemia and systemic vasculitis. The pathogenesis remains poorly understood. 55 consecutive patients with chronic HCI infection (anti-HCV- and serum HCV RNA-positive) were studies prospectively. Cryoglobulinemia was detected in 28 patients (51%)...

journal_title：Zeitschrift fur Gastroenterologie

authors： Hartmann H,Schott P,Polzien F,Mihm S,Uy A,Kaboth U,Pardowitz I,Ramadori G

更新日期：1995-11-01 00:00:00

abstract：:The human gut is colonised by about one kilogram of commensal bacteria. These microorganisms are a potential threat, thus an efficient defence system is crucial in preventing bacterial translocation and infection. Besides other mechanisms of protection humans produce antimicrobial peptides (AMPs) that are able to kill...

journal_title：Zeitschrift fur Gastroenterologie

authors： Schroeder BO,Stange EF,Wehkamp J

更新日期：2012-11-01 00:00:00

abstract：:This report presents a female patient suffering from chronic diarrhea, who developed palpable purpura on the lower extremities 8 weeks after onset of the gastrointestinal symptoms. Biopsies obtained from the colon and skin showed leukocytoclastic vasculitis. Possible triggers or underlying diseases could not be found,...

journal_title：Zeitschrift fur Gastroenterologie

authors： Schartner E,Höflmayer D,Müller-Knespel EM,Dzirlo L,Haunold I,Dawid M,Stanek-Kalchhauser D,Weiss P,Klimpfinger M

更新日期：2013-01-01 00:00:00

abstract：:The oesophagus, stomach and pancreas are primary target organs for ethanol-related diseases. In the oesophagus and stomach, ethanol induces motility disorders and mucosal lesions that are dose-dependent and reversible under acute conditions. Chronic consumption of alcohol causes a significant increase in the risk for ...

journal_title：Zeitschrift fur Gastroenterologie

authors： Siegmund SV,Singer MV

更新日期：2005-08-01 00:00:00

abstract：CASE REPORT:A 72-year-old female patient with known neurofibromatosis type 1 was admitted to the hospital with symptomatic anaemia and a history of melaena. Upper and lower endoscopy did not show any signs of bleeding. Ultrasound and computed tomography revealed an abdominal mass. The histological analysis of a US-guid...

journal_title：Zeitschrift fur Gastroenterologie

authors： Köppen S,Wejda B,Dormann A,Hoffmeister D,Stolte M,Huchzermeyer H

更新日期：2004-10-01 00:00:00

abstract：INTRODUCTION:The exact source of phospholipase A2 is unknown. In this context the liver is discussed because the secretion of phospholipase A2 could be initiated during an acute phase response. PATIENTS AND METHODS:Three groups of patients were prospectively established: A liver resection (n = 12); B control (n = 22; ...

journal_title：Zeitschrift fur Gastroenterologie

authors： Gerhard F,Treusch H,Hofmann GE,Büssow M,Hanisch E

更新日期：1997-04-01 00:00:00

abstract：:Cystic fibrosis (CF) is the most common autosomal recessive disease in the Caucasian population. The primary cellular defect, the reduced expression of the cystic fibrosis transmembrane conductance regulator (CFTR), leading to a chloride secretory defect, is present in all epithelial cells of endodermal and mesodermal...

journal_title：Zeitschrift fur Gastroenterologie

authors： Bargon J,Stein J,Dietrich CF,Müller U,Caspary WF,Wagner TO

更新日期：1999-08-01 00:00:00