解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract:PURPOSE:The liver segments divided by Couinaud classification method are used to understand the functional anatomy of liver, which is significant in hepatic resection surgery. In Couinaud classification method, each third-order branch of the portal vein (PV) defines the supplied territory of a corresponding liver segme...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14745
更新日期:2021-02-02 00:00:00
abstract:PURPOSE:The goal of this work is to propose a new multichannel method correcting for systematic thickness disturbances and to evaluate its precision in relevant radiation dosimetry applications. METHODS:The eigencolor ratio technique is introduced and theoretically developed to provide a method correcting for thicknes...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14742
更新日期:2021-02-01 00:00:00
abstract:PURPOSE:To investigate the feasibility of using the high Zeff storage phosphor material BaFBrI:Eu2+ in conjunction with the low Zeff storage phosphor material KCl:Eu2+ for simultaneous proton dose and linear energy transfer (LET) measurements by 1) measuring the fundamental optical and dosimetric properties of BaFBrI:E...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14748
更新日期:2021-02-01 00:00:00
abstract:PURPOSE:To evaluate the treatment planning system (TPS) performance of the ZAP-X stereotactic radiosurgery (SRS) system through nondosimetric, dosimetric, and end-to-end (E2E) tests. METHODS:A comprehensive set of TPS commissioning and validation tests were developed using published guidelines. Nondosimetric validatio...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14740
更新日期:2021-01-28 00:00:00
abstract:PURPOSE:A nanodosimeter is a type of detector which measures single ionizations in a small gaseous volume in order to obtain ionization cluster size probability distributions for characterization of radiation types. Working nanodosimeter detectors are usually bulky machines which require a lot of space. In this work, t...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14738
更新日期:2021-01-28 00:00:00
abstract:PURPOSE:Precise segmentation of clinical target volume (CTV) is the key to stomach cancer radiotherapy. We proposed a novel stochastic width - deep neural network (SW-DNN) for better automatically contouring stomach CTV METHODS: SW-DNN was an end-to-end approach, of which the core component was a novel SW mechanism tha...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14733
更新日期:2021-01-27 00:00:00
abstract::Most detectors in current positron emission tomography (PET) scanners and prototypes use lutetium oxyorthosilicate (LSO) or lutetium yttrium oxyorthosilicate (LYSO) scintillators. The aim of this work is to provide a complete set of background energy spectra, due to the scintillator intrinsic radioactivity, for a wide...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14729
更新日期:2021-01-21 00:00:00
abstract:PURPOSE:Water equivalent diameter (WED) is the preferred surrogate for patient size in CT. It is better than geometric size surrogates and patient weight/height/BMI/age because it correlates the best with x-ray attenuation. The administration of oral/IV contrast agents increases a patient's attenuation and should there...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14721
更新日期:2021-01-13 00:00:00
abstract:PURPOSE:Material-specific imaging and virtual monochromatic imaging/analysis are the two forms of spectral imaging in CT implemented via either energy-integration or photon-counting data acquisition. Aimed at further understanding the fundamentals and providing guidelines on its design and implementation, we quantitati...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14708
更新日期:2021-01-07 00:00:00
abstract::The use of dedicated magnetic resonance simulation (MR-SIM) platforms in Radiation Oncology has expanded rapidly, introducing new equipment and functionality with the overall goal of improving the accuracy of radiation treatment planning. However, this emerging technology presents a new set of challenges that need to ...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14695
更新日期:2021-01-01 00:00:00
abstract:PURPOSE:Stationary computed tomography (s-CT) conceptually offers several advantages over existing rotating gantry-based CT. Over the last 40 yr, s-CT has been investigated using different technological approaches. We are developing a s-CT system specifically for head/brain imaging using carbon nanotube (CNT)-based fie...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14696
更新日期:2020-12-31 00:00:00
abstract:PURPOSE:Accurate segmentation of lung and infection in COVID-19 computed tomography (CT) scans plays an important role in the quantitative management of patients. Most of the existing studies are based on large and private annotated datasets that are impractical to obtain from a single institution, especially when radi...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14676
更新日期:2020-12-23 00:00:00
abstract:PURPOSE:The segmentation accuracy of medical images was improved by increasing the number of training samples using a local image warping technique. The performance of the proposed method was evaluated in the segmentation of breast masses, prostate and brain tumors, and lung nodules. METHODS:We propose a simple data a...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14651
更新日期:2020-12-10 00:00:00
abstract:PURPOSE:For stereotactic radiosurgery (SRS), accurate evaluation of dose-volume metrics for small structures is necessary. The purpose of this study was to compare the DVH metric capabilities of five commercially available SRS DVH analysis tools (Eclipse, Elements, Raystation, MIM, and Velocity). METHODS:DICOM RTdose ...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14645
更新日期:2020-12-09 00:00:00
abstract:PURPOSE:To develop a computer-driven and thus less user-dependent method, allowing for a simple and straightforward generation of a Monte Carlo (MC) beam model of a scanned proton and carbon ion beam delivery system. METHODS:In a first step, experimental measurements were performed for proton and carbon ion energies i...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14647
更新日期:2020-12-07 00:00:00
abstract:PURPOSE:The local depth dose gradient and the displacement correction factor for Farmer-type ionization chambers are quantified for reference dosimetry at shallow depth in single-layer scanned proton fields. METHOD:Integrated radial profiles as a function of depth (IRPDs) measured at three proton therapy centers were ...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14554
更新日期:2020-12-01 00:00:00
abstract:INTRODUCTION:Ultrasound (US) guidance of the prostate has long been conducted using a transabdominal (TA) approach. More recently, a transperineal (TP) approach has been made available for image guidance. Our aim was to determine if both methods produced similar alignments within the same patients. MATERIALS AND METHO...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14522
更新日期:2020-12-01 00:00:00
abstract:PURPOSE:The number of pencil beam scanned proton therapy (PBS-PT) facilities equipped with cone-beam computed tomography (CBCT) imaging treating thoracic indications is constantly rising. To enable daily internal motion monitoring during PBS-PT treatments of thoracic tumors, we assess the performance of Motion-Aware Re...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14521
更新日期:2020-12-01 00:00:00
abstract:PURPOSE:Tumor motion during radiotherapy can cause a reduction in target dose coverage and an increase in healthy tissue exposure. Tumor motion is not strictly translational and often exhibits complex six degree-of-freedom (6DoF) translational and rotational motion. Although the dosimetric impact of prostate tumor tran...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14502
更新日期:2020-12-01 00:00:00
abstract:PURPOSE:Total and regional body composition are important indicators of health and mortality risk, but their measurement is usually restricted to controlled environments in clinical settings with expensive and specialized equipment. A method that approaches the accuracy of the current gold standard method, dual-energy ...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14492
更新日期:2020-12-01 00:00:00
abstract:PURPOSE:To develop a method of (a) calculating the dose rate of voxels within a proton field delivered using pencil beam scanning (PBS), and (b) reporting a representative dose rate for the PBS treatment field that enables correspondence between multiple treatment modalities. This method takes into account the unique s...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14456
更新日期:2020-12-01 00:00:00
abstract:OBJECTIVE:To develop an anthropomorphic, deformable and multimodal pelvis phantom with positron emission tomography extension for radiotherapy (ADAM PETer). METHODS:The design of ADAM PETer was based on our previous pelvis phantom (ADAM) and extended for compatibility with PET and use in 3T magnetic resonance imaging ...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14597
更新日期:2020-11-18 00:00:00
abstract:PURPOSE:The research is to develop a novel CNN-based adversarial deep learning method to improve and expedite the multi-organ semantic segmentation of CT images and to generate accurate contours on pelvic CT images. METHODS:Planning CT and structure datasets for 120 patients with intact prostate cancer were retrospect...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14580
更新日期:2020-11-05 00:00:00
abstract:PURPOSE:For the past two decades, high-Z nanoparticles have been of high interest to improve the therapeutic outcomes of radiation therapy, especially for low-energy X-rays. Monte Carlo (MC) simulations have been used to evaluate the boost of dose deposition induced by Auger electrons near the nanoparticle surface, by ...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14576
更新日期:2020-11-04 00:00:00
abstract:PURPOSE:Melanoma is the most lethal of the three primary skin cancers, including also basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), which are less lethal. The accepted diagnosis process involves manually observing a suspicious lesion through a Dermascope (i.e., a magnifying glass), followed by a biopsy....
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14471
更新日期:2020-11-01 00:00:00
abstract:PURPOSE:Body composition is known to be associated with many diseases including diabetes, cancers, and cardiovascular diseases. In this paper, we developed a fully automatic body tissue decomposition procedure to segment three major compartments that are related to body composition analysis - subcutaneous adipose tissu...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14465
更新日期:2020-11-01 00:00:00
abstract:PURPOSE:Automatic breast ultrasound (ABUS) imaging has become an essential tool in breast cancer diagnosis since it provides complementary information to other imaging modalities. Lesion segmentation on ABUS is a prerequisite step of breast cancer computer-aided diagnosis (CAD). This work aims to develop a deep learnin...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14569
更新日期:2020-10-30 00:00:00
abstract:PURPOSE:Monitoring of physiological parameters is a major concern in Intensive Care Units (ICU) given their role in the assessment of vital organ function. Within this context, one issue is the lack of efficient noncontact techniques for respiratory monitoring. In this paper, we present a novel noncontact solution for ...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14557
更新日期:2020-10-28 00:00:00
abstract:PURPOSE:In this work the performance of a compact multiresolution and multicontrast x-ray phase system based on edge illumination is investigated. It has been designed for small animal imaging and with a limited footprint for ease of deployment in laboratories. METHODS:The presented edge illumination system is based o...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14553
更新日期:2020-10-27 00:00:00
abstract:PURPOSE:To develop and test the feasibility of a two-pass iterative reconstruction algorithm with material decomposition designed to obtain quantitative iodine measurements in digital breast tomosynthesis. METHODS:Contrast-enhanced mammography has shown promise as a cost-effective alternative to magnetic resonance ima...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14400
更新日期:2020-10-01 00:00:00
abstract:PURPOSE:Tissue textures have been recognized as biomarkers for various clinical tasks. In computed tomography (CT) image reconstruction, it is important but challenging to preserve the texture when lowering x-ray exposure from full- toward low-/ultra-low dose level. Therefore, this paper aims to explore the texture-dos...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14449
更新日期:2020-10-01 00:00:00
abstract:PURPOSE:A dosimetry evaluation model for treatment planning of esophageal radiation therapy is developed using a deep learning model. The model predicts dose volume histogram (DVH) from distance to target histogram (DTH) based on stacked de-noise auto-encoder (SDAE) and one-dimensional convolutional network (1D-CN). M...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14434
更新日期:2020-10-01 00:00:00
abstract:PURPOSE:X-ray microbeam radiation therapy is a preclinical concept for tumor treatment promising tissue sparing and enhanced tumor control. With its spatially separated, periodic micrometer-sized pattern, this method requires a high dose rate and a collimated beam typically available at large synchrotron radiation faci...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14433
更新日期:2020-10-01 00:00:00
abstract:PURPOSE:The response of human cells to applied electrical signals depends on the cellular health status, because it is influenced by the composition and structure of the main cellular components. Therefore, electrical impedance-based techniques can be considered as sensitive tools to investigate healthy or disease stat...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14425
更新日期:2020-10-01 00:00:00
abstract:PURPOSE:High resolution three-dimensional (3D) magnetic resonance (MR) images are well suited for automated cartilage segmentation in the human knee joint. However, volumetric scans such as 3D Double-Echo Steady-State (DESS) images are not routinely acquired in clinical practice which limits opportunities for reliable ...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14421
更新日期:2020-10-01 00:00:00
abstract:PURPOSE:Radiotherapy, especially with charged particles, is sensitive to executional and preparational uncertainties that propagate to uncertainty in dose and plan quality indicators, for example, dose-volume histograms (DVHs). Current approaches to quantify and mitigate such uncertainties rely on explicitly computed e...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14414
更新日期:2020-10-01 00:00:00
abstract:PURPOSE:Particle therapy is becoming increasingly available world-wide for precise tumor targeting, its favorable depth dose deposition, and increased biological damage to tumor tissue compared to conventional photon therapy. As demand increases for improved robustness and conformality, next-generation secondary dose c...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14417
更新日期:2020-10-01 00:00:00
abstract:PURPOSE:Anatomical variations occur during head and neck (H&N) radiotherapy treatment. kV cone-beam computed tomography (CBCT) images can be used for daily dose monitoring to assess dose variations owing to anatomic changes. Deep learning methods (DLMs) have recently been proposed to generate pseudo-CT (pCT) from CBCT ...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14387
更新日期:2020-10-01 00:00:00
abstract:PURPOSE:Recently, brain tumor segmentation has made important progress. However, the quality of manual labels plays an important role in the performance, while in practice, it could vary greatly and in turn could substantially mislead the learning process and decrease the accuracy. We need to design a mechanism to comb...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14480
更新日期:2020-09-24 00:00:00
abstract:PURPOSE:Automated segmentation could improve the efficiency of modeling-based pelvic organ prolapse (POP) evaluations. However, segmentation performance is limited by the blurry soft tissue boundaries. In this study, we aimed to present a hybrid solution for uterus, rectum, bladder, and levator ani muscle segmentation ...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14377
更新日期:2020-09-01 00:00:00