听力与言语-语言病理学

行为科学

医学伦理学

你正在浏览Nanotoxicology期刊下所有文献
  • Occupational exposure to graphene and silica nanoparticles. Part II: pilot study to identify a panel of sensitive biomarkers of genotoxic, oxidative and inflammatory effects on suitable biological matrices.

    abstract::The available biomonitoring studies on workers producing/handling nanomaterials (NMs) focused on potential effects on respiratory, immune and cardio-vascular system. Aim of this study was to identify a panel of sensitive biomarkers and suitable biological matrices to evaluate particularly genotoxic and oxidative effec...

    journal_title:Nanotoxicology

    pub_type: 杂志文章

    doi:10.1080/17435390.2020.1850903

    authors: Ursini CL,Fresegna AM,Ciervo A,Maiello R,Del Frate V,Folesani G,Galetti M,Poli D,Buresti G,Di Cristo L,Sabella S,Iavicoli S,Cavallo D

    更新日期:2020-12-29 00:00:00

  • The sp3/sp2 carbon ratio as a modulator of in vivo and in vitro toxicity of the chemically purified detonation-synthesized nanodiamond via the reactive oxygen species generation.

    abstract::Nanodiamonds have been suggested as biocompatible materials and are suitable for various biomedical applications, but little is known about how to synthesize safer nanodiamonds. Herein, seven different detonation-synthesized nanodiamonds (DNDs) with sequential sp3/sp2 carbon ratios were assembled by controlling the ch...

    journal_title:Nanotoxicology

    pub_type: 杂志文章

    doi:10.1080/17435390.2020.1813825

    authors: Lee DK,Ha S,Jeon S,Jeong J,Kim DJ,Lee SW,Cho WS

    更新日期:2020-11-01 00:00:00

  • Dosimetry in vitro - exploring the sensitivity of deposited dose predictions vs. affinity, polydispersity, freeze-thawing, and analytical methods.

    abstract::Dose-response by in vitro testing is only valid if the fraction of the particle dose that deposits onto adherent cells is known. Modeling tools such as the 'distorted grid' (DG) code are common practices to predict that fraction. As another challenge, workflow efficiency depends on parallelized sample preparation, for...

    journal_title:Nanotoxicology

    pub_type: 杂志文章

    doi:10.1080/17435390.2020.1836281

    authors: Keller JG,Quevedo DF,Faccani L,Costa AL,Landsiedel R,Werle K,Wohlleben W

    更新日期:2020-10-26 00:00:00

  • Role of inflammation in the malignant transformation of pleural mesothelial cells induced by multi-walled carbon nanotubes.

    abstract::Multi-walled carbon nanotubes (MWCNTs) are one of the most widely used types of novel nano-fiber materials. The aim of this study was to establish an experimental system based on actual exposure dosage and environments and explore the roles and mechanisms of inflammation in the malignant transformation of pleural meso...

    journal_title:Nanotoxicology

    pub_type: 杂志文章

    doi:10.1080/17435390.2020.1777477

    authors: Huang X,Tian Y,Shi W,Chen J,Yan L,Ren L,Zhang X,Zhu J

    更新日期:2020-09-01 00:00:00

  • Effect of titanium dioxide nanoparticles on DNA methylation in multiple human cell lines.

    abstract::Nanoscale titanium dioxide (TiO2) is manufactured in wide scale, with a range of applications in consumer products. Significant toxicity of TiO2 nanoparticles has, however, been recognized, suggesting considerable risk to human health. To evaluate fully their toxicity, assessment of the epigenetic action of these nano...

    journal_title:Nanotoxicology

    pub_type: 杂志文章

    doi:10.1080/17435390.2020.1723730

    authors: Pogribna M,Koonce NA,Mathew A,Word B,Patri AK,Lyn-Cook B,Hammons G

    更新日期:2020-05-01 00:00:00

  • Organ burden of inhaled nanoceria in a 2-year low-dose exposure study: dump or depot?

    abstract::No detailed information on in vivo biokinetics of CeO2 nanoparticles (NPs) following chronic low-dose inhalation is available. The CeO2 burden for lung, lung-associated lymph nodes, and major non-pulmonary organs, blood, and feces, was determined in a chronic whole-body inhalation study in female Wistar rats undertake...

    journal_title:Nanotoxicology

    pub_type: 杂志文章

    doi:10.1080/17435390.2020.1736355

    authors: Tentschert J,Laux P,Jungnickel H,Brunner J,Estrela-Lopis I,Merker C,Meijer J,Ernst H,Ma-Hock L,Keller J,Landsiedel R,Luch A

    更新日期:2020-05-01 00:00:00

  • Do the joint effects of size, shape and ecocorona influence the attachment and physical eco(cyto)toxicity of nanoparticles to algae?

    abstract::We systematically investigated how the combinations of size, shape and the natural organic matter (NOM)-ecocorona of gold (Au) engineered nanoparticles (ENPs) influence the attachment of the particles to algae and physical toxicity to the cells. Spherical (10, 60 and 100 nm), urchin-shaped (60 nm), rod-shaped (10 × 45...

    journal_title:Nanotoxicology

    pub_type: 杂志文章

    doi:10.1080/17435390.2019.1692381

    authors: Abdolahpur Monikh F,Arenas-Lago D,Porcal P,Grillo R,Zhang P,Guo Z,Vijver MG,J G M Peijnenburg W

    更新日期:2020-04-01 00:00:00

  • 28-Day inhalation toxicity study with evaluation of lung deposition and retention of tangled multi-walled carbon nanotubes.

    abstract::Lung deposition and retention measurements are now required by the newly revised OECD inhalation toxicity testing guidelines 412 and 413 when evaluating the clearance and biopersistence of poorly soluble nanomaterials, such as multi-walled carbon nanotubes (MWCNTs). However, evaluating the lung deposition concentratio...

    journal_title:Nanotoxicology

    pub_type: 杂志文章

    doi:10.1080/17435390.2019.1700568

    authors: Kim JK,Jo MS,Kim Y,Kim TG,Shin JH,Kim BW,Kim HP,Lee HK,Kim HS,Ahn K,Oh SM,Cho WS,Yu IJ

    更新日期:2020-03-01 00:00:00

  • The effects of nano-sized PbO on biomarkers of membrane disruption and DNA damage in a sub-chronic inhalation study on mice.

    abstract::Although the production of engineered nanoparticles increases our knowledge of toxicity and mechanisms of bioactivity during relevant exposures is lacking. In the present study mice were exposed to PbO nanoparticles (PbONP; 192.5 µg/m3; 1.93 × 106 particles/cm3) for 2, 5 and 13 weeks through continuous inhalation. The...

    journal_title:Nanotoxicology

    pub_type: 杂志文章

    doi:10.1080/17435390.2019.1685696

    authors: Bláhová L,Nováková Z,Večeřa Z,Vrlíková L,Dočekal B,Dumková J,Křůmal K,Mikuška P,Buchtová M,Hampl A,Hilscherová K,Bláha L

    更新日期:2020-03-01 00:00:00

  • Disposition and measured toxicity of zinc oxide nanoparticles and zinc ions against keratinocytes in cell culture and viable human epidermis.

    abstract::Suspensions of the UV filter, zinc oxide nanoparticles (ZnO NP), are widely used in sunscreen products. This paper compared the relative disposition and local cytotoxicity of ZnO NP, and zinc ions formed on its dissolution, against keratinocyte cultures and in the human epidermis (ex vivo) after application of suspens...

    journal_title:Nanotoxicology

    pub_type: 杂志文章

    doi:10.1080/17435390.2019.1692382

    authors: Holmes AM,Mackenzie L,Roberts MS

    更新日期:2020-03-01 00:00:00

  • Iron nanoparticle bio-interactions evaluated in Xenopus laevis embryos, a model for studying the safety of ingested nanoparticles.

    abstract::Iron nanoparticles (NPs) have been proposed as a tool in very different fields such as environmental remediation and biomedical applications, including food fortification against iron deficiency, even if there is still concern about their safety. Here, we propose Xenopus laevis embryos as a suitable model to investiga...

    journal_title:Nanotoxicology

    pub_type: 杂志文章

    doi:10.1080/17435390.2019.1685695

    authors: Bonfanti P,Colombo A,Saibene M,Fiandra L,Armenia I,Gamberoni F,Gornati R,Bernardini G,Mantecca P

    更新日期:2020-03-01 00:00:00

  • Copper oxide nanoparticles alter cellular morphology via disturbing the actin cytoskeleton dynamics in Arabidopsis roots.

    abstract::Copper oxide nanoparticles (CuO NPs) have severe nano-toxic effects on organisms. Limited data is available on influence of CuO NPs on plant cells. Here, the molecular mechanisms involved in the toxicity of CuO NPs are studied. Exposure to CuO NPs significantly increased copper content in roots (0.062-0.325 mg/g FW), ...

    journal_title:Nanotoxicology

    pub_type: 杂志文章

    doi:10.1080/17435390.2019.1678693

    authors: Jia H,Chen S,Wang X,Shi C,Liu K,Zhang S,Li J

    更新日期:2020-02-01 00:00:00

  • Assessment of potential toxicity of foodborne fluorescent nanoparticles from roasted pork.

    abstract::Foodborne nanoparticles (NPs) refer to the nanostructures generated during food processing, rather than the man-made nano-structural additives that are added to improve the property of food. In this research, discovery of fluorescent NPs in roasted pork was reported at different temperature of 180, 230, and 280 °C. Th...

    journal_title:Nanotoxicology

    pub_type: 杂志文章

    doi:10.1080/17435390.2019.1652943

    authors: Zhao X,Shan S,Li J,Cao L,Lv J,Tan M

    更新日期:2019-12-01 00:00:00

  • Exposure to Al2O3 nanoparticles facilitates conjugative transfer of antibiotic resistance genes from Escherichia coli to Streptomyces.

    abstract::The spread of antibiotic resistance genes (ARGs) has become a global environmental issue; it has been found that nanoparticles (NPs) can promote the transfer of ARGs between bacteria. However, it remains unclear whether NPs can affect this kind of conjugation in Streptomyces, which mainly conjugate with other bacteria...

    journal_title:Nanotoxicology

    pub_type: 杂志文章

    doi:10.1080/17435390.2019.1669731

    authors: Liu X,Tang J,Song B,Zhen M,Wang L,Giesy JP

    更新日期:2019-12-01 00:00:00

  • Elevated internalization and cytotoxicity of polydispersed single-walled carbon nanotubes in activated B cells can be basis for preferential depletion of activated B cells in vivo.

    abstract::Uptake of polydispersed acid-functionalized single-walled carbon nanotubes (AF-SWCNTs) in resting and LPS-activated B cells was studied using fluorescence-tagged AF-SWCNTs (FAF-SWCNTs). Activated B cells internalized substantially higher amounts of FAF-SWCNTs [76.5% AF-SWCNT+ B cells, mean fluorescence intensity (MFI)...

    journal_title:Nanotoxicology

    pub_type: 杂志文章

    doi:10.1080/17435390.2019.1593541

    authors: Dutt TS,Mia MB,Saxena RK

    更新日期:2019-08-01 00:00:00

  • Role of p53 in the chronic pulmonary immune response to tangled or rod-like multi-walled carbon nanotubes.

    abstract::The fiber-like shape of multi-walled carbon nanotubes (MWCNTs) is reminiscent of asbestos, suggesting they pose similar health hazards when inhaled, including pulmonary fibrosis and mesothelioma. Mice deficient in the tumor suppressor p53 are susceptible to carcinogenesis. However, the chronic pathologic effect of MWC...

    journal_title:Nanotoxicology

    pub_type: 杂志文章

    doi:10.1080/17435390.2018.1502830

    authors: Duke KS,Thompson EA,Ihrie MD,Taylor-Just AJ,Ash EA,Shipkowski KA,Hall JR,Tokarz DA,Cesta MF,Hubbs AF,Porter DW,Sargent LM,Bonner JC

    更新日期:2018-11-01 00:00:00

  • Biodistribution and biocompatibility of passion fruit-like nano-architectures in zebrafish.

    abstract::Passion fruit-like nano-architectures (NAs) are all-in-one platforms of increasing interest for the translation of metal nanoparticles into clinics. NAs are nature-inspired disassembling inorganic theranostics, which jointly combine most of the appealing behaviors of noble metal nanoparticles with their potential orga...

    journal_title:Nanotoxicology

    pub_type: 杂志文章

    doi:10.1080/17435390.2018.1498551

    authors: d'Amora M,Cassano D,Pocoví-Martínez S,Giordani S,Voliani V

    更新日期:2018-10-01 00:00:00

  • Antigenotoxic potential of boron nitride nanotubes.

    abstract::Boron and boron nitride nanotubes (BNNTs) are increasingly used in different industrial fields and, potentially, in some biomedical areas. As occurs with other nanomaterials (NMs), to increase our knowledge on their potential health hazards is a priority. Although in vitro approaches are a routine in getting biologica...

    journal_title:Nanotoxicology

    pub_type: 杂志文章

    doi:10.1080/17435390.2018.1482379

    authors: Demir E,Marcos R

    更新日期:2018-10-01 00:00:00

  • Gold nanoparticles ingested by oyster larvae are internalized by cells through an alimentary endocytic pathway.

    abstract::The biological fate of nanoparticles (NPs) taken up by organisms from their environment is a crucial issue for assessing ecological hazard. Despite its importance, it has scarcely been addressed due to the technical difficulties of doing so in whole organism in vivo studies. Here, by using transmission electron micros...

    journal_title:Nanotoxicology

    pub_type: 杂志文章

    doi:10.1080/17435390.2018.1487601

    authors: Noventa S,Hacker C,Correia A,Drago C,Galloway T

    更新日期:2018-10-01 00:00:00

  • Evaluation of toxicological and teratogenic effects of carbosilane glucose glycodendrimers in zebrafish embryos and model rodent cell lines.

    abstract::Glycodendrimers (Glyco-DDMs) represent a rapidly growing class of nanoparticles with promising properties for biomedical applications but concerns regarding the impact on human health and environment are still justified. Here we report, for the first time, the comparative study of in vivo developmental toxicity of car...

    journal_title:Nanotoxicology

    pub_type: 杂志文章

    doi:10.1080/17435390.2018.1475582

    authors: Liegertová M,Wrobel D,Herma R,Müllerová M,Šťastná LČ,Cuřínová P,Strašák T,Malý M,Čermák J,Smejkal J,Štofik M,Maly J

    更新日期:2018-10-01 00:00:00

  • Copper nanoparticles induce early fibrotic changes in the liver via TGF-β/Smad signaling and cause immunosuppressive effects in rats.

    abstract::Copper nanoparticles (Cu NPs) have various uses, including as additives in polymers/plastics, lubricants for metallic coating, and biomedical applications. We investigated the role of transforming growth factor (TGF)-β1 signaling in hepatic damage caused by Cu NPs and explored the effects of a 28-day repeated oral adm...

    journal_title:Nanotoxicology

    pub_type: 杂志文章

    doi:10.1080/17435390.2018.1472313

    authors: Lee IC,Ko JW,Park SH,Shin NR,Shin IS,Moon C,Kim SH,Yun WK,Kim HC,Kim JC

    更新日期:2018-08-01 00:00:00

  • Inflammation in the pleural cavity following injection of multi-walled carbon nanotubes is dependent on their characteristics and the presence of IL-1 genes.

    abstract::Upon inhalation, multi-walled carbon nanotubes (MWCNTs) may reach the subpleura and pleural spaces, and induce pleural inflammation and/or mesothelioma in humans. However, the mechanisms of MWCNT-induced pathology after direct intrapleural injections are still only partly elucidated. In particular, a role of the proin...

    journal_title:Nanotoxicology

    pub_type: 杂志文章

    doi:10.1080/17435390.2018.1465139

    authors: Arnoldussen YJ,Skaug V,Aleksandersen M,Ropstad E,Anmarkrud KH,Einarsdottir E,Chin-Lin F,Granum Bjørklund C,Kasem M,Eilertsen E,Apte RN,Zienolddiny S

    更新日期:2018-08-01 00:00:00

  • Elucidating differential nano-bio interactions of multi-walled andsingle-walled carbon nanotubes using subcellular proteomics.

    abstract::Understanding the relationship between adverse exposure events and specific material properties will facilitate predictive classification of carbon nanotubes (CNTs) according to their mechanisms of action, and a safe-by-design approach for the next generation of CNTs. Mass-spectrometry-based proteomics is a reliable t...

    journal_title:Nanotoxicology

    pub_type: 杂志文章

    doi:10.1080/17435390.2018.1465141

    authors: Ndika JDT,Sund J,Alenius H,Puustinen A

    更新日期:2018-08-01 00:00:00

  • Dendritic polyglycerol nanoparticles show charge dependent bio-distribution in early human placental explants and reduce hCG secretion.

    abstract::A thorough understanding of nanoparticle bio-distribution at the feto-maternal interface will be a prerequisite for their diagnostic or therapeutic application in women of childbearing age and for teratologic risk assessment. Therefore, the tissue interaction of biocompatible dendritic polyglycerol nanoparticles (dPG-...

    journal_title:Nanotoxicology

    pub_type: 杂志文章

    doi:10.1080/17435390.2018.1425496

    authors: Juch H,Nikitina L,Reimann S,Gauster M,Dohr G,Obermayer-Pietsch B,Hoch D,Kornmueller K,Haag R

    更新日期:2018-03-01 00:00:00

  • Reactive oxygen species damage drives cardiac and mitochondrial dysfunction following acute nano-titanium dioxide inhalation exposure.

    abstract::Nanotechnology offers innovation in products from cosmetics to drug delivery, leading to increased engineered nanomaterial (ENM) exposure. Unfortunately, health impacts of ENM are not fully realized. Titanium dioxide (TiO2) is among the most widely produced ENM due to its use in numerous applications. Extrapulmonary e...

    journal_title:Nanotoxicology

    pub_type: 杂志文章

    doi:10.1080/17435390.2017.1416202

    authors: Nichols CE,Shepherd DL,Hathaway QA,Durr AJ,Thapa D,Abukabda A,Yi J,Nurkiewicz TR,Hollander JM

    更新日期:2018-02-01 00:00:00

  • Fluorescent nanoparticles present in Coca-Cola and Pepsi-Cola: physiochemical properties, cytotoxicity, biodistribution and digestion studies.

    abstract::Foodborne nanoparticles (NPs) have drawn great attention due to human health concerns. This study reports the detection of the presence of fluorescent NPs, about 5 nm, in two of the most popular beverages, Coca-Cola (Coke) and Pepsi-Cola (Pepsi). The NPs contain H, C and O, three elements with a tunable emission and w...

    journal_title:Nanotoxicology

    pub_type: 杂志文章

    doi:10.1080/17435390.2017.1418443

    authors: Li S,Jiang C,Wang H,Cong S,Tan M

    更新日期:2018-02-01 00:00:00

  • Amplification of arsenic genotoxicity by TiO2 nanoparticles in mammalian cells: new insights from physicochemical interactions and mitochondria.

    abstract::Titanium dioxide nanoparticles (TiO2 NPs) have shown great adsorption capacity for arsenic (As); however, the potential impact of TiO2 NPs on the behavior and toxic responses of As remains largely unexplored. In the present study, we focused on the physicochemical interaction between TiO2 NPs and As(III) to clarify th...

    journal_title:Nanotoxicology

    pub_type: 杂志文章

    doi:10.1080/17435390.2017.1388861

    authors: Wang X,Liu Y,Wang J,Nie Y,Chen S,Hei TK,Deng Z,Wu L,Zhao G,Xu A

    更新日期:2017-10-01 00:00:00

  • Continuous in vitro exposure of intestinal epithelial cells to E171 food additive causes oxidative stress, inducing oxidation of DNA bases but no endoplasmic reticulum stress.

    abstract::The whitening and opacifying properties of titanium dioxide (TiO2) are commonly exploited when it is used as a food additive (E171). However, the safety of this additive can be questioned as TiO2 nanoparticles (TiO2-NPs) have been classed at potentially toxic. This study aimed to shed some light on the mechanisms behi...

    journal_title:Nanotoxicology

    pub_type: 杂志文章

    doi:10.1080/17435390.2017.1349203

    authors: Dorier M,Béal D,Marie-Desvergne C,Dubosson M,Barreau F,Houdeau E,Herlin-Boime N,Carriere M

    更新日期:2017-08-01 00:00:00

  • Oral subchronic exposure to silver nanoparticles causes renal damage through apoptotic impairment and necrotic cell death.

    abstract::Silver nanoparticles (AgNPs) are one of the most widely used nanomaterials. Following oral exposure, AgNPs can accumulate in various organs including kidneys where they show gender specific accumulation. There is limited information on their effect on renal system following long-term animal exposure especially at the ...

    journal_title:Nanotoxicology

    pub_type: 杂志文章

    doi:10.1080/17435390.2017.1343874

    authors: Tiwari R,Singh RD,Khan H,Gangopadhyay S,Mittal S,Singh V,Arjaria N,Shankar J,Roy SK,Singh D,Srivastava V

    更新日期:2017-06-01 00:00:00

  • Complete transformation of ZnO and CuO nanoparticles in culture medium and lymphocyte cells during toxicity testing.

    abstract::Here, we present evidence on complete transformation of ZnO and CuO nanoparticles, which are among the most heavily studied metal oxide particles, during 24 h in vitro toxicological testing with human T-lymphocytes. Synchrotron radiation-based X-ray absorption near edge structure (XANES) spectroscopy results revealed ...

    journal_title:Nanotoxicology

    pub_type: 杂志文章

    doi:10.1080/17435390.2017.1282049

    authors: Ivask A,Scheckel KG,Kapruwan P,Stone V,Yin H,Voelcker NH,Lombi E

    更新日期:2017-03-01 00:00:00

  • Toxicity of TiO2 nanoparticles on soil nitrification at environmentally relevant concentrations: Lack of classical dose-response relationships.

    abstract::Titanium-dioxide nanoparticles (TiO2-NPs) are increasingly released in agricultural soils through, e.g. biosolids, irrigation or nanoagrochemicals. Soils are submitted to a wide range of concentrations of TiO2-NPs depending on the type of exposure. However, most studies have assessed the effects of unrealistically hig...

    journal_title:Nanotoxicology

    pub_type: 杂志文章

    doi:10.1080/17435390.2017.1290845

    authors: Simonin M,Martins JM,Le Roux X,Uzu G,Calas A,Richaume A

    更新日期:2017-03-01 00:00:00

  • Distinct toxic interactions of TiO2 nanoparticles with four coexisting organochlorine contaminants on algae.

    abstract::Engineered nanoparticles are increasingly discharged into the environment. After discharge, these nanoparticles can interact with co-existing organic contaminants, resulting in a phenomena referred to as 'joint toxicity'. This study evaluated joint toxicities of TiO2 nanoparticles (TiO2NPs) with four different (atrazi...

    journal_title:Nanotoxicology

    pub_type: 杂志文章

    doi:10.1080/17435390.2017.1398358

    authors: Zhang S,Deng R,Lin D,Wu F

    更新日期:2017-01-01 00:00:00

  • Predicting toxic potencies of metal oxide nanoparticles by means of nano-QSARs.

    abstract:BACKGROUND:The enormous physicochemical and structural diversity of metal oxide nanoparticles (MeONPs) poses significant challenges to the testing of their biological uptake, biodistribution, and effects that can be used to develop understanding of key nano-bio modes of action. This has generated considerable uncertain...

    journal_title:Nanotoxicology

    pub_type: 杂志文章

    doi:10.1080/17435390.2016.1202352

    authors: Mu Y,Wu F,Zhao Q,Ji R,Qie Y,Zhou Y,Hu Y,Pang C,Hristozov D,Giesy JP,Xing B

    更新日期:2016-11-01 00:00:00

  • Translocation of 40 nm diameter nanowires through the intestinal epithelium of Daphnia magna.

    abstract::Nanowires (NWs) have unique electrical and optical properties of value for many applications including lighting, sensing, and energy harnessing. Consumer products containing NWs increase the risk of NWs being released in the environment, especially into aquatic ecosystems through sewage systems. Daphnia magna is a com...

    journal_title:Nanotoxicology

    pub_type: 杂志文章

    doi:10.1080/17435390.2016.1189615

    authors: Mattsson K,Adolfsson K,Ekvall MT,Borgström MT,Linse S,Hansson LA,Cedervall T,Prinz CN

    更新日期:2016-10-01 00:00:00

  • Occupational exposure limit for silver nanoparticles: considerations on the derivation of a general health-based value.

    abstract::With the increased production and widespread commercial use of silver nanoparticles (AgNPs), human and environmental exposures to silver nanoparticles are inevitably increasing. In particular, persons manufacturing and handling silver nanoparticles and silver nanoparticle containing products are at risk of exposure, p...

    journal_title:Nanotoxicology

    pub_type: 杂志文章

    doi:10.3109/17435390.2016.1148793

    authors: Weldon BA,M Faustman E,Oberdörster G,Workman T,Griffith WC,Kneuer C,Yu IJ

    更新日期:2016-09-01 00:00:00

  • Accurate and interpretable nanoSAR models from genetic programming-based decision tree construction approaches.

    abstract::The number of engineered nanomaterials (ENMs) being exploited commercially is growing rapidly, due to the novel properties they exhibit. Clearly, it is important to understand and minimize any risks to health or the environment posed by the presence of ENMs. Data-driven models that decode the relationships between the...

    journal_title:Nanotoxicology

    pub_type: 杂志文章

    doi:10.3109/17435390.2016.1161857

    authors: Oksel C,Winkler DA,Ma CY,Wilkins T,Wang XZ

    更新日期:2016-09-01 00:00:00

  • 28-Day inhalation toxicity of graphene nanoplatelets in Sprague-Dawley rats.

    abstract::Graphene, a two-dimensional engineered nanomaterial, is now being used in many applications, such as electronics, biological engineering, filtration, lightweight and strong nanocomposite materials, and energy storage. However, there is a lack of information on the potential health effects of graphene in humans based o...

    journal_title:Nanotoxicology

    pub_type: 杂志文章

    doi:10.3109/17435390.2015.1133865

    authors: Kim JK,Shin JH,Lee JS,Hwang JH,Lee JH,Baek JE,Kim TG,Kim BW,Kim JS,Lee GH,Ahn K,Han SG,Bello D,Yu IJ

    更新日期:2016-09-01 00:00:00

  • Safety and toxicity of nanomaterials for ocular drug delivery applications.

    abstract::Multifunctional nanomaterials are rapidly emerging for ophthalmic delivery of therapeutics to facilitate safe and effective targeting with improved patient compliance. Because of their extremely high area to volume ratio, nanomaterials often have physicochemical properties that are different from those of their larger...

    journal_title:Nanotoxicology

    pub_type: 杂志文章,评审

    doi:10.3109/17435390.2016.1153165

    authors: Mehra NK,Cai D,Kuo L,Hein T,Palakurthi S

    更新日期:2016-09-01 00:00:00

  • New insights in the acute toxic/genotoxic effects of CuO nanoparticles in the in vivo Drosophila model.

    abstract::Metal oxide nanoparticles are highly reactive from the biological point of view and, for this reason, it exists important reservations in regard human health impact. We used Drosophila as a promising in vivo model to diagnose the biological effects of copper oxide nanoparticles (CuO-NPs). Due to the potential role of ...

    journal_title:Nanotoxicology

    pub_type: 杂志文章

    doi:10.3109/17435390.2015.1121413

    authors: Alaraby M,Hernández A,Marcos R

    更新日期:2016-08-01 00:00:00

  • Harmful effects of silver nanoparticles on a complex detrital model system.

    abstract::The rapid proliferation of silver nanoparticles (AgNP) in industry and the environment requires realistic toxicity assessments based on approaches that consider the biological complexity of ecosystems. Here we assessed the acute toxicity of carbonate-coated AgNP and, for comparison, AgNO3 (Ag(+)) by using a model syst...

    journal_title:Nanotoxicology

    pub_type: 杂志文章

    doi:10.3109/17435390.2015.1117673

    authors: Tlili A,Cornut J,Behra R,Gil-Allué C,Gessner MO

    更新日期:2016-08-01 00:00:00

93 条记录 1/3 页 « 123 »