Role of p53 in the chronic pulmonary immune response to tangled or rod-like multi-walled carbon nanotubes.

abstract：:The printer is one of the most common office equipment. Recently, it was reported that toner formulations for printing equipment constitute nano-enabled products (NEPs) and contain engineered nanomaterials (ENMs) that become airborne during printing. To date, insufficient research has been performed to understand the ...

journal_title：Nanotoxicology

authors： Sisler JD,Pirela SV,Friend S,Farcas M,Schwegler-Berry D,Shvedova A,Castranova V,Demokritou P,Qian Y

更新日期：2015-01-01 00:00:00

abstract：:This study aims to assess the effects of Ag particles synthesised by a chemical (Ag 20, 200 nm) and biological method (Ag 23, 27 nm) in aquatic organisms: the bacterium Vibrio fischeri, the alga Desmodesmus subspicatus and the crustacean Daphnia magna. Ag particles exerted toxic effects in all organisms studied with A...

journal_title：Nanotoxicology

authors： Georgantzopoulou A,Balachandran YL,Rosenkranz P,Dusinska M,Lankoff A,Wojewodzka M,Kruszewski M,Guignard C,Audinot JN,Girija S,Hoffmann L,Gutleb AC

更新日期：2013-11-01 00:00:00

abstract：:Copper oxide nanoparticles (CuO NPs) have severe nano-toxic effects on organisms. Limited data is available on influence of CuO NPs on plant cells. Here, the molecular mechanisms involved in the toxicity of CuO NPs are studied. Exposure to CuO NPs significantly increased copper content in roots (0.062-0.325 mg/g FW), ...

journal_title：Nanotoxicology

authors： Jia H,Chen S,Wang X,Shi C,Liu K,Zhang S,Li J

更新日期：2020-02-01 00:00:00

abstract：:The addition of a transmitted electron detector to a scanning electron microscope (SEM) allows the recording of bright and dark field scanning transmission electron microscope (STEM) images and the corresponding in-lens secondary electron images from the same region of a thin sample. These combined imaging techniques ...

journal_title：Nanotoxicology

authors： Hondow N,Harrington J,Brydson R,Doak SH,Singh N,Manshian B,Brown A

更新日期：2011-06-01 00:00:00

abstract：:Little information exists on the toxicological hazards associated to organo-modified clays. We evaluated the cytotoxicity of a series of pristine and organo-modified nanoclays in different cell lines. The calculated IC50 values for cell viability ranged from 1.4 to 47 µg/mL for the six organoclays used and were above ...

journal_title：Nanotoxicology

authors： Janer G,Fernández-Rosas E,Mas del Molino E,González-Gálvez D,Vilar G,López-Iglesias C,Ermini V,Vázquez-Campos S

更新日期：2014-05-01 00:00:00

abstract：:Raphidocelis subcapitata is a freshwater algae species that constitutes the basis of many aquatic trophic chains. In this study, R. subcapitata was used as a model species to investigate the kinetics of uptake and elimination of silver nanoparticles (AgNP) in comparison to silver nitrate (AgNO3) with particular focus ...

journal_title：Nanotoxicology

authors： Ribeiro F,Gallego-Urrea JA,Goodhead RM,Van Gestel CA,Moger J,Soares AM,Loureiro S

更新日期：2015-01-01 00:00:00

abstract：:Iron nanoparticles (NPs) have been proposed as a tool in very different fields such as environmental remediation and biomedical applications, including food fortification against iron deficiency, even if there is still concern about their safety. Here, we propose Xenopus laevis embryos as a suitable model to investiga...

journal_title：Nanotoxicology

authors： Bonfanti P,Colombo A,Saibene M,Fiandra L,Armenia I,Gamberoni F,Gornati R,Bernardini G,Mantecca P

更新日期：2020-03-01 00:00:00

abstract：:Despite the rapid ongoing expansion in the use of nanomaterials, we still know little about their biological interaction and biodistribution within the human body. If medically relevant nanoparticles can cross specific cell barriers they may disseminate through the body beyond the original target and may reach particu...

journal_title：Nanotoxicology

authors： Correia Carreira S,Walker L,Paul K,Saunders M

更新日期：2015-05-01 00:00:00

abstract：:Inhalation of zinc oxide nanoparticles (ZnONP) has potential health impact. Because zinc ion may involve in the toxicity of ZnONP, we compared adverse effects of inhaled aerosolized ZnONP and zinc nitrate in mice. Aerosolized ZnONP and zinc nitrate were well-dispersed in the inhalation chamber. Inhalation of 0.86 mg/m...

journal_title：Nanotoxicology

authors： Chen JK,Ho CC,Chang H,Lin JF,Yang CS,Tsai MH,Tsai HT,Lin P

更新日期：2015-02-01 00:00:00

abstract：:Six TiO₂ and two CeO₂ nanomaterials with dry sizes ranging from 6-410 nm were tested for their ability to cause DNA centered free radicals in vitro in the concentration range of 10-3,000 ug/ml. All eight of the nanomaterials significantly increased the adduction of the spin trap agent 5,5-dimethyl-1-pyroline N-oxide (...

journal_title：Nanotoxicology

authors： Kitchin KT,Prasad RY,Wallace K

更新日期：2011-12-01 00:00:00

abstract：:Nanowires (NWs) have unique electrical and optical properties of value for many applications including lighting, sensing, and energy harnessing. Consumer products containing NWs increase the risk of NWs being released in the environment, especially into aquatic ecosystems through sewage systems. Daphnia magna is a com...

journal_title：Nanotoxicology

authors： Mattsson K,Adolfsson K,Ekvall MT,Borgström MT,Linse S,Hansson LA,Cedervall T,Prinz CN

更新日期：2016-10-01 00:00:00

abstract：:We systematically investigated how the combinations of size, shape and the natural organic matter (NOM)-ecocorona of gold (Au) engineered nanoparticles (ENPs) influence the attachment of the particles to algae and physical toxicity to the cells. Spherical (10, 60 and 100 nm), urchin-shaped (60 nm), rod-shaped (10 × 45...

journal_title：Nanotoxicology

authors： Abdolahpur Monikh F,Arenas-Lago D,Porcal P,Grillo R,Zhang P,Guo Z,Vijver MG,J G M Peijnenburg W

更新日期：2020-04-01 00:00:00

abstract：:Abstract To examine gold nanoparticle reprotoxicity, bovine spermatozoa were challenged with ligand-free or oligonucleotide-conjugated gold nanoparticles synthesized purely without any surfactants by laser ablation. Sperm motility declined at nanoparticle mass dose of 10 µg/ml (corresponding to ∼14 000 nanoparticles p...

journal_title：Nanotoxicology

authors： Taylor U,Barchanski A,Petersen S,Kues WA,Baulain U,Gamrad L,Sajti L,Barcikowski S,Rath D

更新日期：2014-08-01 00:00:00

abstract：:Multifunctional nanomaterials are rapidly emerging for ophthalmic delivery of therapeutics to facilitate safe and effective targeting with improved patient compliance. Because of their extremely high area to volume ratio, nanomaterials often have physicochemical properties that are different from those of their larger...

journal_title：Nanotoxicology

authors： Mehra NK,Cai D,Kuo L,Hein T,Palakurthi S

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:The enormous physicochemical and structural diversity of metal oxide nanoparticles (MeONPs) poses significant challenges to the testing of their biological uptake, biodistribution, and effects that can be used to develop understanding of key nano-bio modes of action. This has generated considerable uncertain...

journal_title：Nanotoxicology

authors： Mu Y,Wu F,Zhao Q,Ji R,Qie Y,Zhou Y,Hu Y,Pang C,Hristozov D,Giesy JP,Xing B

更新日期：2016-11-01 00:00:00

abstract：:If engineered nanomaterials are released into the environment, some are likely to end up associated with the food of animals due to aggregation and sorption processes. However, few studies have considered dietary exposure of nanomaterials. Here we show that zinc (Zn) from isotopically modified (67)ZnO particles is eff...

journal_title：Nanotoxicology

authors： Croteau MN,Dybowska AD,Luoma SN,Valsami-Jones E

更新日期：2011-03-01 00:00:00

abstract：:Titanium dioxide nanoparticles (TiO2 NPs) have shown great adsorption capacity for arsenic (As); however, the potential impact of TiO2 NPs on the behavior and toxic responses of As remains largely unexplored. In the present study, we focused on the physicochemical interaction between TiO2 NPs and As(III) to clarify th...

journal_title：Nanotoxicology

authors： Wang X,Liu Y,Wang J,Nie Y,Chen S,Hei TK,Deng Z,Wu L,Zhao G,Xu A

更新日期：2017-10-01 00:00:00

abstract：:The increasing presence of ZnO nanoparticles (NPs) in consumer products may be having a dramatic impact in aquatic environments. The evaluation of ZnO NP toxicity represents a great challenge. This study aimed at evaluating the cytotoxic effect of micro- and nanosized ZnO in a fish and a mammalian hepatoma cell line. ...

journal_title：Nanotoxicology

authors： Fernández-Cruz ML,Lammel T,Connolly M,Conde E,Barrado AI,Derick S,Perez Y,Fernandez M,Furger C,Navas JM

更新日期：2013-08-01 00:00:00

abstract：:With the increased production and widespread commercial use of silver nanoparticles (AgNPs), human and environmental exposures to silver nanoparticles are inevitably increasing. In particular, persons manufacturing and handling silver nanoparticles and silver nanoparticle containing products are at risk of exposure, p...

journal_title：Nanotoxicology

authors： Weldon BA,M Faustman E,Oberdörster G,Workman T,Griffith WC,Kneuer C,Yu IJ

更新日期：2016-09-01 00:00:00

abstract：:Enhanced in vitro human and ex vivo rat platelet aggregation from direct exposure to silver nanoparticles is previously reported. Given the increasing human use of engineered silver nanoscale products, platelet aggregation prompted by silver nanoparticles may contribute to human cardiovascular events. To understand ho...

journal_title：Nanotoxicology

authors： Smock KJ,Schmidt RL,Hadlock G,Stoddard G,Grainger DW,Munger MA

更新日期：2014-05-01 00:00:00

abstract：:The spread of antibiotic resistance genes (ARGs) has become a global environmental issue; it has been found that nanoparticles (NPs) can promote the transfer of ARGs between bacteria. However, it remains unclear whether NPs can affect this kind of conjugation in Streptomyces, which mainly conjugate with other bacteria...

journal_title：Nanotoxicology

authors： Liu X,Tang J,Song B,Zhen M,Wang L,Giesy JP

更新日期：2019-12-01 00:00:00

abstract：:Graphene, a two-dimensional engineered nanomaterial, is now being used in many applications, such as electronics, biological engineering, filtration, lightweight and strong nanocomposite materials, and energy storage. However, there is a lack of information on the potential health effects of graphene in humans based o...

journal_title：Nanotoxicology

authors： Kim JK,Shin JH,Lee JS,Hwang JH,Lee JH,Baek JE,Kim TG,Kim BW,Kim JS,Lee GH,Ahn K,Han SG,Bello D,Yu IJ

更新日期：2016-09-01 00:00:00

abstract：:The available biomonitoring studies on workers producing/handling nanomaterials (NMs) focused on potential effects on respiratory, immune and cardio-vascular system. Aim of this study was to identify a panel of sensitive biomarkers and suitable biological matrices to evaluate particularly genotoxic and oxidative effec...

journal_title：Nanotoxicology

authors： Ursini CL,Fresegna AM,Ciervo A,Maiello R,Del Frate V,Folesani G,Galetti M,Poli D,Buresti G,Di Cristo L,Sabella S,Iavicoli S,Cavallo D

更新日期：2020-12-29 00:00:00

abstract：:Silver nanoparticles (Ag-NPs) are used in a wide variety of products, prompting concerns regarding their potential environmental impacts. To accurately determine the toxicity of Ag-NPs it is necessary to differentiate between the toxicity of the nanoparticles themselves and the toxicity of ionic silver (Ag) released f...

journal_title：Nanotoxicology

authors： Sekine R,Khurana K,Vasilev K,Lombi E,Donner E

更新日期：2015-01-01 00:00:00

abstract：:Due to the increasing use of nanometric cerium oxide in applications, concerns about the toxicity of these particles have been raised and have resulted in a large number of studies. We report here on the interactions between 7 nm anionically charged cerium oxide particles and living mammalian cells. By a modification ...

journal_title：Nanotoxicology

authors： Ould-Moussa N,Safi M,Guedeau-Boudeville MA,Montero D,Conjeaud H,Berret JF

更新日期：2014-11-01 00:00:00

abstract：:Since nanomaterials are a heterogeneous group of substances used in various applications, risk assessment needs to be done on a case-by-case basis. Here the authors assess the risk (hazard and exposure) of a glass cleaner with synthetic amorphous silicon dioxide (SAS) nanoparticles during production and consumer use (...

journal_title：Nanotoxicology

authors： Michel K,Scheel J,Karsten S,Stelter N,Wind T

更新日期：2013-08-01 00:00:00

abstract：:ZnO nanoparticles (NPs) elicit significant adverse effects in various cell types, organisms and in the environment. The toxicity of nanoscale ZnO has often been ascribed to the release of zinc ions from the NPs but it is not yet understood to which extent these ions contribute to ZnO NP toxicity and what are the under...

journal_title：Nanotoxicology

authors： Buerki-Thurnherr T,Xiao L,Diener L,Arslan O,Hirsch C,Maeder-Althaus X,Grieder K,Wampfler B,Mathur S,Wick P,Krug HF

更新日期：2013-06-01 00:00:00

abstract：:A thorough understanding of nanoparticle bio-distribution at the feto-maternal interface will be a prerequisite for their diagnostic or therapeutic application in women of childbearing age and for teratologic risk assessment. Therefore, the tissue interaction of biocompatible dendritic polyglycerol nanoparticles (dPG-...

journal_title：Nanotoxicology

authors： Juch H,Nikitina L,Reimann S,Gauster M,Dohr G,Obermayer-Pietsch B,Hoch D,Kornmueller K,Haag R

更新日期：2018-03-01 00:00:00

abstract：:Despite the increasing commercial use of nanoparticles, little is known about their effects on placental inflammation and pregnancy complications. In this study, nanosilica (NS) particles upregulated the inflammasome component nucleotide-binding oligomerization domain-like receptor (NLR) family pyrin domain-containing...

journal_title：Nanotoxicology

authors： Shirasuna K,Usui F,Karasawa T,Kimura H,Kawashima A,Mizukami H,Ohkuchi A,Nishimura S,Sagara J,Noda T,Ozawa K,Taniguchi S,Takahashi M

更新日期：2015-01-01 00:00:00

abstract：:Lung deposition and retention measurements are now required by the newly revised OECD inhalation toxicity testing guidelines 412 and 413 when evaluating the clearance and biopersistence of poorly soluble nanomaterials, such as multi-walled carbon nanotubes (MWCNTs). However, evaluating the lung deposition concentratio...

journal_title：Nanotoxicology

authors： Kim JK,Jo MS,Kim Y,Kim TG,Shin JH,Kim BW,Kim HP,Lee HK,Kim HS,Ahn K,Oh SM,Cho WS,Yu IJ

更新日期：2020-03-01 00:00:00