Ag nanoparticles: size- and surface-dependent effects on model aquatic organisms and uptake evaluation with NanoSIMS.

abstract：:The spread of antibiotic resistance genes (ARGs) has become a global environmental issue; it has been found that nanoparticles (NPs) can promote the transfer of ARGs between bacteria. However, it remains unclear whether NPs can affect this kind of conjugation in Streptomyces, which mainly conjugate with other bacteria...

journal_title：Nanotoxicology

authors： Liu X,Tang J,Song B,Zhen M,Wang L,Giesy JP

更新日期：2019-12-01 00:00:00

abstract：:We systematically investigated how the combinations of size, shape and the natural organic matter (NOM)-ecocorona of gold (Au) engineered nanoparticles (ENPs) influence the attachment of the particles to algae and physical toxicity to the cells. Spherical (10, 60 and 100 nm), urchin-shaped (60 nm), rod-shaped (10 × 45...

journal_title：Nanotoxicology

authors： Abdolahpur Monikh F,Arenas-Lago D,Porcal P,Grillo R,Zhang P,Guo Z,Vijver MG,J G M Peijnenburg W

更新日期：2020-04-01 00:00:00

abstract：:There is a paucity of data regarding the safety of administering solid gold nanoparticles (AuNPs) in large animal tumor models. We assessed the acute toxicity and biodistribution of 5 nm and 25 nm solid AuNPs in New Zealand White rabbits (n = 6 in each) with implanted liver Vx2 tumors 24 h after intravenous injection....

journal_title：Nanotoxicology

authors： Glazer ES,Zhu C,Hamir AN,Borne A,Thompson CS,Curley SA

更新日期：2011-12-01 00:00:00

abstract：:Nanowires (NWs) have unique electrical and optical properties of value for many applications including lighting, sensing, and energy harnessing. Consumer products containing NWs increase the risk of NWs being released in the environment, especially into aquatic ecosystems through sewage systems. Daphnia magna is a com...

journal_title：Nanotoxicology

authors： Mattsson K,Adolfsson K,Ekvall MT,Borgström MT,Linse S,Hansson LA,Cedervall T,Prinz CN

更新日期：2016-10-01 00:00:00

abstract：:Little information exists on the toxicological hazards associated to organo-modified clays. We evaluated the cytotoxicity of a series of pristine and organo-modified nanoclays in different cell lines. The calculated IC50 values for cell viability ranged from 1.4 to 47 µg/mL for the six organoclays used and were above ...

journal_title：Nanotoxicology

authors： Janer G,Fernández-Rosas E,Mas del Molino E,González-Gálvez D,Vilar G,López-Iglesias C,Ermini V,Vázquez-Campos S

更新日期：2014-05-01 00:00:00

abstract：:The levels of exposure and internal doses of nanomaterials are becoming more and more important for estimating the health effects resulting from exposure to nanomaterials. Health surveillance can be used as an indicator of whether exposure is occurring, rather than in determining if levels of exposure are safe. We hav...

journal_title：Nanotoxicology

authors： Lee JH,Mun J,Park JD,Yu IJ

更新日期：2012-09-01 00:00:00

abstract：:Copper nanoparticles (Cu NPs) have various uses, including as additives in polymers/plastics, lubricants for metallic coating, and biomedical applications. We investigated the role of transforming growth factor (TGF)-β1 signaling in hepatic damage caused by Cu NPs and explored the effects of a 28-day repeated oral adm...

journal_title：Nanotoxicology

authors： Lee IC,Ko JW,Park SH,Shin NR,Shin IS,Moon C,Kim SH,Yun WK,Kim HC,Kim JC

更新日期：2018-08-01 00:00:00

abstract：:Growing experimental evidences suggest the existence of direct relationships between the surface chemistry of nanomaterials and their biological effects. Herein, we have employed computational approaches to design a set of biologically active carbon nanotubes (CNTs) with controlled protein binding and cytotoxicity. Qu...

journal_title：Nanotoxicology

authors： Fourches D,Pu D,Li L,Zhou H,Mu Q,Su G,Yan B,Tropsha A

更新日期：2016-01-01 00:00:00

abstract：:Iron nanoparticles (NPs) have been proposed as a tool in very different fields such as environmental remediation and biomedical applications, including food fortification against iron deficiency, even if there is still concern about their safety. Here, we propose Xenopus laevis embryos as a suitable model to investiga...

journal_title：Nanotoxicology

authors： Bonfanti P,Colombo A,Saibene M,Fiandra L,Armenia I,Gamberoni F,Gornati R,Bernardini G,Mantecca P

更新日期：2020-03-01 00:00:00

abstract：:Engineered nanoparticles are increasingly used in medical applications and day-to-day consumer products, leading to concerns about the potential environmental and human health impacts. Silver nanoparticles are particularly prevalent because of their use as anti-bacterial agents in many commonly available products. Nan...

journal_title：Nanotoxicology

authors： Kermanizadeh A,Chauché C,Balharry D,Brown DM,Kanase N,Boczkowski J,Lanone S,Stone V

更新日期：2014-08-01 00:00:00

abstract：:Understanding the relationship between adverse exposure events and specific material properties will facilitate predictive classification of carbon nanotubes (CNTs) according to their mechanisms of action, and a safe-by-design approach for the next generation of CNTs. Mass-spectrometry-based proteomics is a reliable t...

journal_title：Nanotoxicology

authors： Ndika JDT,Sund J,Alenius H,Puustinen A

更新日期：2018-08-01 00:00:00

abstract：:The rapid proliferation of silver nanoparticles (AgNP) in industry and the environment requires realistic toxicity assessments based on approaches that consider the biological complexity of ecosystems. Here we assessed the acute toxicity of carbonate-coated AgNP and, for comparison, AgNO3 (Ag(+)) by using a model syst...

journal_title：Nanotoxicology

authors： Tlili A,Cornut J,Behra R,Gil-Allué C,Gessner MO

更新日期：2016-08-01 00:00:00

abstract：:The use of imaging tools to probe nanoparticle-cell interactions will be crucial to elucidating the mechanisms of nanoparticle-induced toxicity. Of particular interest are mechanisms associated with cell penetration, translocation and subsequent accumulation inside the cell, or in cellular compartments. The objective ...

journal_title：Nanotoxicology

authors： Tantra R,Knight A

更新日期：2011-09-01 00:00:00

abstract：:A thorough understanding of nanoparticle bio-distribution at the feto-maternal interface will be a prerequisite for their diagnostic or therapeutic application in women of childbearing age and for teratologic risk assessment. Therefore, the tissue interaction of biocompatible dendritic polyglycerol nanoparticles (dPG-...

journal_title：Nanotoxicology

authors： Juch H,Nikitina L,Reimann S,Gauster M,Dohr G,Obermayer-Pietsch B,Hoch D,Kornmueller K,Haag R

更新日期：2018-03-01 00:00:00

abstract：:Despite the rapid ongoing expansion in the use of nanomaterials, we still know little about their biological interaction and biodistribution within the human body. If medically relevant nanoparticles can cross specific cell barriers they may disseminate through the body beyond the original target and may reach particu...

journal_title：Nanotoxicology

authors： Correia Carreira S,Walker L,Paul K,Saunders M

更新日期：2015-05-01 00:00:00

abstract：:Raphidocelis subcapitata is a freshwater algae species that constitutes the basis of many aquatic trophic chains. In this study, R. subcapitata was used as a model species to investigate the kinetics of uptake and elimination of silver nanoparticles (AgNP) in comparison to silver nitrate (AgNO3) with particular focus ...

journal_title：Nanotoxicology

authors： Ribeiro F,Gallego-Urrea JA,Goodhead RM,Van Gestel CA,Moger J,Soares AM,Loureiro S

更新日期：2015-01-01 00:00:00

abstract：:Effects of maternal pulmonary exposure to carbon black (Printex 90) on gestation, lactation and DNA strand breaks were evaluated. Time-mated C57BL/6BomTac mice were exposed by inhalation to 42 mg/m(3) Printex 90 for 1 h/day on gestation days (GD) 8-18, or by four intratracheal instillations on GD 7, 10, 15 and 18, wit...

journal_title：Nanotoxicology

authors： Jackson P,Hougaard KS,Boisen AM,Jacobsen NR,Jensen KA,Møller P,Brunborg G,Gutzkow KB,Andersen O,Loft S,Vogel U,Wallin H

更新日期：2012-08-01 00:00:00

abstract：:Certain types of carbon nanotubes (CNT) can evoke inflammation, fibrosis and mesothelioma in vivo, raising concerns about their potential health effects. It has been recently postulated that NLRP3 inflammasome activation is important in the CNT-induced toxicity. However, more comprehensive studies of the protein secre...

journal_title：Nanotoxicology

authors： Palomäki J,Sund J,Vippola M,Kinaret P,Greco D,Savolainen K,Puustinen A,Alenius H

更新日期：2015-01-01 00:00:00

abstract：:Although the production of engineered nanoparticles increases our knowledge of toxicity and mechanisms of bioactivity during relevant exposures is lacking. In the present study mice were exposed to PbO nanoparticles (PbONP; 192.5 µg/m3; 1.93 × 106 particles/cm3) for 2, 5 and 13 weeks through continuous inhalation. The...

journal_title：Nanotoxicology

authors： Bláhová L,Nováková Z,Večeřa Z,Vrlíková L,Dočekal B,Dumková J,Křůmal K,Mikuška P,Buchtová M,Hampl A,Hilscherová K,Bláha L

更新日期：2020-03-01 00:00:00

abstract：:Despite the wide use of silver nanoparticles (nano Ag), its toxicity still remains poorly understood. In this report, nano Ag induced an increase in platelet aggregation and procoagulant activation which are the key contributors to thrombotic diseases. In freshly isolated human platelets, nano Ag induced platelet aggr...

journal_title：Nanotoxicology

authors： Jun EA,Lim KM,Kim K,Bae ON,Noh JY,Chung KH,Chung JH

更新日期：2011-06-01 00:00:00

abstract：:The effect of non-functionalized and amino-functionalized multiwall carbon nanotube (CNT) exposure, as well as the impact of CNT presence on coexistent pesticide accumulation, was investigated in lettuce (Lactuca sativa L.). Lettuce seeds were sown directly into CNT-amended vermiculite (1000 mg L(-1)) to monitor phyto...

journal_title：Nanotoxicology

authors： Hamdi H,De La Torre-Roche R,Hawthorne J,White JC

更新日期：2015-03-01 00:00:00

abstract：:The current study tests the hypothesis that multi-walled carbon nanotubes (MWCNT) with different surface chemistries exhibit different bioactivity profiles in vivo. In addition, the study examined the potential contribution of the NLRP3 inflammasome in MWCNT-induced lung pathology. Unmodified (BMWCNT) and MWCNT that w...

journal_title：Nanotoxicology

authors： Sager TM,Wolfarth MW,Andrew M,Hubbs A,Friend S,Chen TH,Porter DW,Wu N,Yang F,Hamilton RF,Holian A

更新日期：2014-05-01 00:00:00

abstract：:No detailed information on in vivo biokinetics of CeO2 nanoparticles (NPs) following chronic low-dose inhalation is available. The CeO2 burden for lung, lung-associated lymph nodes, and major non-pulmonary organs, blood, and feces, was determined in a chronic whole-body inhalation study in female Wistar rats undertake...

journal_title：Nanotoxicology

authors： Tentschert J,Laux P,Jungnickel H,Brunner J,Estrela-Lopis I,Merker C,Meijer J,Ernst H,Ma-Hock L,Keller J,Landsiedel R,Luch A

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:The enormous physicochemical and structural diversity of metal oxide nanoparticles (MeONPs) poses significant challenges to the testing of their biological uptake, biodistribution, and effects that can be used to develop understanding of key nano-bio modes of action. This has generated considerable uncertain...

journal_title：Nanotoxicology

authors： Mu Y,Wu F,Zhao Q,Ji R,Qie Y,Zhou Y,Hu Y,Pang C,Hristozov D,Giesy JP,Xing B

更新日期：2016-11-01 00:00:00

abstract：:Upon inhalation, multi-walled carbon nanotubes (MWCNTs) may reach the subpleura and pleural spaces, and induce pleural inflammation and/or mesothelioma in humans. However, the mechanisms of MWCNT-induced pathology after direct intrapleural injections are still only partly elucidated. In particular, a role of the proin...

journal_title：Nanotoxicology

authors： Arnoldussen YJ,Skaug V,Aleksandersen M,Ropstad E,Anmarkrud KH,Einarsdottir E,Chin-Lin F,Granum Bjørklund C,Kasem M,Eilertsen E,Apte RN,Zienolddiny S

更新日期：2018-08-01 00:00:00

abstract：:Multifunctional nanomaterials are rapidly emerging for ophthalmic delivery of therapeutics to facilitate safe and effective targeting with improved patient compliance. Because of their extremely high area to volume ratio, nanomaterials often have physicochemical properties that are different from those of their larger...

journal_title：Nanotoxicology

authors： Mehra NK,Cai D,Kuo L,Hein T,Palakurthi S

更新日期：2016-09-01 00:00:00

abstract：:Enhanced in vitro human and ex vivo rat platelet aggregation from direct exposure to silver nanoparticles is previously reported. Given the increasing human use of engineered silver nanoscale products, platelet aggregation prompted by silver nanoparticles may contribute to human cardiovascular events. To understand ho...

journal_title：Nanotoxicology

authors： Smock KJ,Schmidt RL,Hadlock G,Stoddard G,Grainger DW,Munger MA

更新日期：2014-05-01 00:00:00

abstract：:Here, we present evidence on complete transformation of ZnO and CuO nanoparticles, which are among the most heavily studied metal oxide particles, during 24 h in vitro toxicological testing with human T-lymphocytes. Synchrotron radiation-based X-ray absorption near edge structure (XANES) spectroscopy results revealed ...

journal_title：Nanotoxicology

authors： Ivask A,Scheckel KG,Kapruwan P,Stone V,Yin H,Voelcker NH,Lombi E

更新日期：2017-03-01 00:00:00

abstract：:With the advent of nanoparticles produced in high quantities and employed in products or processes, the need to evaluate their potential toxicological effects is necessary. For this purpose, biopersistence studies are needed to assess the possible effects of nanoparticles in parallel with a proper characterization. Th...

journal_title：Nanotoxicology

authors： Lozano O,Mejia J,Masereel B,Toussaint O,Lison D,Lucas S

更新日期：2012-05-01 00:00:00

abstract：:Engineered nanoparticles are increasingly discharged into the environment. After discharge, these nanoparticles can interact with co-existing organic contaminants, resulting in a phenomena referred to as 'joint toxicity'. This study evaluated joint toxicities of TiO2 nanoparticles (TiO2NPs) with four different (atrazi...

journal_title：Nanotoxicology

authors： Zhang S,Deng R,Lin D,Wu F

更新日期：2017-01-01 00:00:00